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Jiarui Mi @jiaruimi.bsky.social · 05/06/2025

nice overview of the mechanisms of beta cell regeneration! Big congrats!!!

Reposted by Jiarui Mi

Olov Andersson @o-andersson-lab.bsky.social · 01/06/2025

Our paper has been out for a while but was included in today's issue, featuring our cover suggestion made by the brilliant Mattias Karlen www.nature.com/nchembio/vol... @ckarampelias.bsky.social @uu.se

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Reposted by Jiarui Mi

Christos Karampelias @ckarampelias.bsky.social · 14/03/2025

Happy to share our work on pancreatic ductal organoids from the human-relevant pig model across developmental stages ranging from embryonic to adult animals and using them for drug screening applications from the @heikolickert.bsky.social lab. #PancSky #devbio 🧪🧬 www.biorxiv.org/content/10.1... /1

biorxiv.org

Benchmarking porcine pancreatic ductal organoids for drug screening applications

Primary human pancreatic ductal organoids (HPDO) have emerged as a model to study pancreas biology and disease. Yet, donor material availability, and a lack of extensive benchmarking limits the range ...

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Reposted by Jiarui Mi

Arnau Sebé-Pedrós @arnausebe.bsky.social · 03/03/2025

We offer three new positions to join BCA Phase 0: 1. A full-stack developer to work on the BCA database with @ebi.embl.org 2. A senior research technician to develop sc methods 3. A bioinformatician to analyze new atlases with @sangerinstitute.bsky.social Details below. Please, share and repost.

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Reposted by Jiarui Mi

Prisca Liberali @priscaliberali.bsky.social · 15/01/2025

A perfect start in the new year! 🌱 Regenerating tissues are just an amazing spatio temporal controlled process! Our new manuscript explores how cell heterogeneity and bistability orchestrate intestinal regeneration. 🧵 biorxiv.org/cgi/content/...

biorxiv.org

Cell heterogeneity and fate bistability drive tissue patterning during intestinal regeneration

Tissue regeneration relies on the ability of cells to undergo de novo patterning. While tissue patterning has been viewed as the transition from initially identical un-patterned cells to an arrangemen...

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Reposted by Jiarui Mi

Carissa Birznieks @c-birznieks.bsky.social · 24/02/2025

Such a cool paper!! #PancSky

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Reposted by Jiarui Mi

Christos Karampelias @ckarampelias.bsky.social · 02/01/2025

I tried to make a feed for news and discussions on all things pancreas biology (exocrine and endocrine!). You can post with the hashtags #PancSky #BetaCellSky #EndocrineSky . Let me know if it is useful and how to modify to make it better! bsky.app/profile/did:...

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Reposted by Jiarui Mi

Max Wilkinson @maxewilkinson.bsky.social · 01/03/2025

we recently found some really neat RNA-guided DNA-cutting systems in phages. Despite remarkable similarities to CRISPR systems, including encoding guide RNAs in arrays, they appear entirely evolutionarily distinct (but definitely related to snoRNAs 🤓) We decided to call them TIGR-Tas systems 🐯

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Reposted by Jiarui Mi

The Rockefeller University @rockefeller.edu · 05/02/2025

Rockefeller's @cicacanesso.bsky.social talks to The Scientist about her recent work with @danmucida.bsky.social and @victora.bsky.social on how cell-cell interactions help drive tolerogenic or inflammatory responses to the maelstrom of antigens passing through the gut.

the-scientist.com

How Does the Gut Immune System Distinguish Between Friends and Foes?

Cell-cell interactions help drive tolerogenic or inflammatory responses to the maelstrom of antigens passing through the gut.

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Reposted by Jiarui Mi

Fabian Theis @fabiantheis.bsky.social · 22/01/2025

Excited to see Moscot (moscot-tools.org) published in @Nature! We scaled Optimal Transport (OT) in single-cell genomics & added multimodality together with spatiotemporal trajectory inference, finding exciting new biology in the pancreas! 🚀 Read at www.nature.com/articles/s41...

nature.com

Mapping cells through time and space with moscot - Nature

Moscot is an optimal transport approach that overcomes current limitations of similar methods to enable multimodal, scalable and consistent single-cell analyses of datasets across spatial and temporal...

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Jiarui Mi @jiaruimi.bsky.social · 11/01/2025

👍👍 thank you for the fabulous team work!

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