iiinova — where your digital self keeps evolving

Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 25/09/2026

Microbial studies need more than answers. They need scale. 🧬 One Vega SPRQ-Nx run can support up to 384 microbial de novo assembly samples, 96 shotgun metagenomic profiling communities, or 1,536 Kinnex 16S rRNA communities. 📖 Download the playbook: bit.ly/4zJLPV4

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Jeremy Wilkinson @jewilki.bsky.social · 22/09/2026

I’m very excited for these exceptional projects! Congrats again to the winners.

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 23/06/2026

Missed us at #ASMicrobe 2026? Move from research to implementation with our updated pre-clinical playbook, now enhanced with new clinical data, cancer research applications, and expanded technical guidance. Download the guide: bit.ly/4mpZ85b #PacBio #MicrobialGenomics #ClinicalResearch

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Jeremy Wilkinson @jewilki.bsky.social · 18/06/2026

When are you making the switch from wrong reads to long reads? Check out Rob Knight’s presentation on this for metagenomics at the link below!

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Jeremy Wilkinson @jewilki.bsky.social · 11/06/2026

I hope you’ll join us for this webinar rebroadcast with me online to answer any questions you may have about PacBio for #longread #microbiome and #metagenomics. In case you missed it last September.

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 05/06/2026

Fewer than 1% of microbes have been identified. Our new blog explores how PacBio HiFi sequencing delivers the strain-level resolution needed to see them clearly: bit.ly/4ujuLRQ At #ASMicrobe in D.C. today? Stop by booth #1325 to see our systems and chat with our team!

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 07/06/2026

It is the final day of #ASMicrobe 2026! Don't miss your last chance to stop by booth #1325. Meet our team, see live demos of our Vega and Revio systems, and learn how #PacBio HiFi sequencing can advance your microbial genomics research. See you there!

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Jeremy Wilkinson @jewilki.bsky.social · 02/06/2026

Apply with your metagenomics projects! Let me know if you have any questions.

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 26/05/2026

SPRQ-Nx chemistry is now shipping worldwide, bringing sub-$300 HiFi genomes to the Revio platform! This global rollout cuts sequencing costs by 30%, making it easier than ever to scale high-throughput workflows Full press release here: bit.ly/49HwmcL #SPRQNx #PacBio #HiFisequencing #Revio

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 21/05/2026

Long-read sequencing has come a long way. With SPRQ-Nx chemistry, PacBio has driven costs down to $6 per Gb. New to HiFi? Download our Starter Kit to get a technology guide, decision tree, and planning checklist. Get the kit here: bit.ly/41ePDxQ #TheresHiFiForThat #PacBio #HiFisequencing

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Jeremy Wilkinson @jewilki.bsky.social · 20/05/2026

Hope you’ll join us for this webinar!

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 20/05/2026

Wondering if your lab can actually afford HiFi long-read sequencing? In question 4, we break down the cost. A 20x human genome on Revio with SPRQ-Nx runs at about $300, giving you premium #PacBio accuracy on a budget. Watch the full breakdown here: bit.ly/4cBxnVp #TheresHiFiForThat

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Reposted by Jeremy Wilkinson

Gang Fang @gangfang.bsky.social · 19/05/2026

Glad that our paper is out today in @cp-cellhostmicrobe.bsky.social A baby received a routine course of amoxicillin. In that infant's #gut 💩, we could see something remarkable, already present **before** the antibiotic arriveda single strain 🦠 of #Akkermansia muciniphila was already running 1/n

cell.com

Epigenetic phase variation in the gut microbiome enhances bacterial adaptation

Ni et al. show that epigenetic phase variation (ePV)—gene expression changes mediated by bacterial DNA methylation—is prevalent in the human gut microbiome and associated with fluctuating environments...

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Jeremy Wilkinson @jewilki.bsky.social · 19/05/2026

We’re at the #sfafmeeting. My first time being at this conference since 2017. Looking forward to lots of great talks and conversations. Come see us if you’re here. @pacbio.bsky.social #HiFi #longreads

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Jeremy Wilkinson @jewilki.bsky.social · 18/05/2026

Stop by and say hi if you’ll be at ASM!

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Jeremy Wilkinson @jewilki.bsky.social · 06/05/2026

We hope you’ll join us for this webinar!

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Jeremy Wilkinson @jewilki.bsky.social · 28/04/2026

I’d love to catch up if you’ll be at APHL! See you there.

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 13/04/2026

Excitement is building in Barcelona! 🇪🇸 #PacBioPRISM 2026 is officially here. We’re kicking things off with 200+ guests and 25+ expert-led talks on the way. We can't wait to see the latest in HiFi sequencing and discovery over the next few days. #PacBio

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 26/03/2026

Successful AI models are built on data that is high-quality, complete, and rich in biological context. Basecamp Research is using PacBio HiFi sequencing to move beyond fragmented snapshots and build a richer map of biology. Read the blog here: bit.ly/4svvj6N #PacBio #HiFisequencing #Genomics

bit.ly

How HiFi metagenomic sequencing is powering AI-driven discovery with Basecamp Research - PacBio

Basecamp Research’s recent selection of PacBio HiFi sequencing to support its Trillion Gene Atlas initiative highlights an important shift in biological AI.

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Jeremy Wilkinson @jewilki.bsky.social · 18/03/2026

Very excited for this MASSIVE #metagenomics project and can't wait to see everything that will be discovered! #longreads

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Reposted by Jeremy Wilkinson

Gang Fang @gangfang.bsky.social · 05/02/2026

New Preprint 📢 from our team 🔎 Critical assessment of #intratumor and #low #biomass #microbiome using #longread sequencing Some studies suggest bacteria 🦠 live inside tumors and influence cancer treatment. But there’s also been a major #debate: in these very low-microbe tissue samples, how much 1/

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 26/01/2026

🎬✨Now streaming: BEYOND THE BENCH This season features: • Santosha Vardhana on immune cell exhaustion and RNA splicing • Andor Kiss on bringing HiFi into teaching • Birgitt Schüele on repeat expansions across populations Press play → bit.ly/4oLrOXu #BeyondTheBench #PacBio #TheresHiFiForThat

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Jeremy Wilkinson @jewilki.bsky.social · 15/01/2026

I’m now at the wastewater symposium! Come say hi if you’re here and talk about high accuracy #longread sequencing for #microbial, #microbiome, and #metagenomics. @pacbio.bsky.social

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 08/01/2026

Introducing CiFi from #PacBio and UC Davis! It combines 3C with HiFi long reads to generate chromosome-scale, haplotype-resolved assemblies from a single SMRT Cell. Minimal samples, fewer runs, and maximum insight into complex genomes. Discover CiFi with us at #PAG33. Details: bit.ly/4qLpVvb

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 04/12/2025

Countdown starts now. The genomics series we’ve all been waiting for – a #PacBio original series. Trailer’s out. Premiere’s coming. Add it to your watchlist 👇 🔗 bit.ly/4oLrOXu

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 19/11/2025

Just 5 spots left! Apply for your chance to attend a 2026 genomics conference with flights, hotel, and registration covered. Meet HiFi sequencing experts and take your research further. Apply now: bit.ly/4oJQxvy #PacBio #TheresHiFiForThat #HiFisequencing #Conferences

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 19/11/2025

#Antimicrobial resistance is a global threat but understanding it starts with complete data. #PacBio HiFi reveals more complete plasmids, resistance genes, & mobile elements with high accuracy. Let’s sequence smarter to fight antimicrobial resistance. 🔗 bit.ly/4rgthrd #AMR

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 30/10/2025

The 2026 #PacBio Genomics Conference Giveaway is LIVE! Travel, registration, and hotel on us. Here’s why showing up matters, straight from Amino Chain’s Jelani Clarke. 👉 Apply here: bit.ly/4oJQxvy #TheresHiFiForThat #PacBio #Conferences

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Jeremy Wilkinson @jewilki.bsky.social · 03/11/2025

I’ll be at AMP. If you’ll be there, let me know and maybe we can catch up.

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Jeremy Wilkinson @jewilki.bsky.social · 18/10/2025

We’re at another @zymoresearch.bsky.social Biofestival at Harvard University. Come say hi if you’re here. @pacbio.bsky.social

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 17/10/2025

👀 ICYMI: During ASHG, we unveiled the next era of SMRT Cells and our new SPRQ-Nx chemistry on Revio, enabling comprehensive genomes for under $300 at scale. Beta access is now open, and spots are limited. Read our press release for more details: bit.ly/4o06eyH #ASHG25 #PacBio #SPRQNx #Revio

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 17/10/2025

Our #ASHG25 PacBio Industry Workshop begins in one hour at 12:00pm in Room 153ABC, Level 1! Join speakers from Genome Institute of Singapore and Johns Hopkins University to celebrate 25 years of genomics, HiFi sequencing advances, and collaborative discoveries. #PacBio #ASHG #HiFisequencing

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Jeremy Wilkinson @jewilki.bsky.social · 17/10/2025

We’re at the @zymoresearch.bsky.social biofestival at the University of Maryland. Come say hi if you’re here. @pacbio.bsky.social

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Reposted by Jeremy Wilkinson

MVLS Shared Research Facilities @mvls-srf.bsky.social · 16/10/2025

We are very excited to offer PacBio Long Read Sequencing in @molecularanalysis.bsky.social ! If you are interested, please get in touch: www.gla.ac.uk/colleges/mvl... You can also save the date - 14 Nov - as we will be hosting reps from PacBio. More details to follow!

Poster with an image of a PacBio Vega instrument, and the text: Molecular Analysis; New Technology; PacBio Vega Long Read Sequencing;
Genome Assembly:
Novel strains
CpG methylation
Metagenomics:
Species and strain resolution
Transcriptomics:
de novo assembly
Differential splicing

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Reposted by Jeremy Wilkinson

Dan Portik @dportik.bsky.social · 15/10/2025

Another #metagenome assembly algorithm for #PacBio HiFi data - introducing Alice! I'll be very interested to see how this performs on some of our trickier datasets. More broadly, I'm happy to see continual development of tools for long-read #metagenomics. doi.org/10.1101/2025...

doi.org

Alice: fast and haplotype-aware assembly of high-fidelity reads based on MSR sketching

We introduce Mapping-friendly Sequence Reduction (MSR) sketches, a sketching method for high-fidelity (HiFi) long reads, and Alice, an as-sembler that operates directly on these sketches. MSR produces...

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Reposted by Jeremy Wilkinson

BYTESEU @byteseu.bsky.social · 15/10/2025

South Korea selects PacBio HiFi Technology for National Pangenome Project www.byteseu.com/1453735 South Korea selects PacBio HiFi Technology for National Pangenome Project October 14, 2025 | Tuesday | News More than 1,000 Korean genomes to be sequenced for global reference standards …

byteseu.com

South Korea selects PacBio HiFi Technology for National Pangenome Project - Bytes Europe

October 14, 2025 | Tuesday | News

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 14/10/2025

#PacBio announces major upcoming advances for #Revio and #Vega designed to lower genome costs, expand multiomic capabilities, and support regulated research. The SPRQ-Nx chemistry, now in beta access, delivers complete genomes for under $300 at scale. View the press release: bit.ly/4o06eyH

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Reposted by Jeremy Wilkinson

Allison G @assemblerag.bsky.social · 01/10/2025

Here are a few highlights: We first identified a 1.58 Mbp plasmid in an infant gut metagenome thanks to @pacbio.bsky.social sequencing. The average bacterial genome size in these communities is usually less than 5 Mbp so this was curious to us. We then found similar elements in other infants.

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Reposted by Jeremy Wilkinson

Allison G @assemblerag.bsky.social · 01/10/2025

Most plasmids described in E. coli are small compared to the megaplasmids we identified here! Check out the preprint if you want to learn about these mysterious large elements and their potential functions 🧬. I’m very grateful to have had the opportunity to work on this in @banfieldlab.bsky.social

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Jeremy Wilkinson @jewilki.bsky.social · 25/09/2025

In the latest issue of DDW Journal, I explore how long-read genomics is driving high-resolution microbiome profiling and why precision microbiomics is set to become the next foundational layer in the drug discovery toolkit. 🧬 Read the full article here. 👉 bit.ly/4mq1xwp #microbiome #longreads

bit.ly

DDW Fall 2025 - Drug Discovery World (DDW)

The DDW Fall issue examines why there is a need for a universal pneumococcal vaccine, why China might be the next global biopharma powerhouse and looks at developments in microbiome research and the t...

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Jeremy Wilkinson @jewilki.bsky.social · 25/09/2025

Join us tomorrow if you can. Link below to register.

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 16/09/2025

Science award? (The Scientist’s Top Innovations 2025) ✅ Design award? (Fast Company’s Innovation by Design 2025) ✅ Sequencer that’s turning heads everywhere? Vega. 🔥 #Vega #PacBio #HiFiSequencing

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 17/09/2025

Microbes may be small, but the discoveries they drive are huge! 🦠 This #InternationalMicroorganismDay, see how #PacBio HiFi sequencing is uncovering microbial mysteries, from mapping hidden HIV-1 reservoirs to revealing novel AMR pathways. Details here: bit.ly/4mSgPeL

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Reposted by Jeremy Wilkinson

Hutlab @hutlab.bsky.social · 17/09/2025

Long and Kelsey just won the 2025 Microbiome SMRT Grant for HiFi shotgun metagenomics!! They will collaborate to optimize PacBio-compatible protocols for gut metagenomics, specifically generating high quality long-read data from IBD patients. Congrats to both! 🎉 🎉 www.pacb.com/blog/2025-mi...

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Reposted by Jeremy Wilkinson

PacBio @pacbio.bsky.social · 15/09/2025

The 2025 Long-Read Low Pass SMRT Grant for plant + animal sciences is now open! 🌱🐾 Apply to win free PacBio HiFi sequencing for your conservation or agricultural research. Submit your 100-word proposal today: bit.ly/3IgrReu #PacBio #SMRTGrant #HiFisequencing

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