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Jeff Lange

@jeffjlange.bsky.social
972 followers 1K following 147 posts

Microscopist, biologist, chemist Opinions expressed are my own.

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Reposted by Jeff Lange
Science Magazine @science.org · 05/10/2026
Exclusive: A new analysis refutes James Watson’s claim that he was the first to recognize the significance of the famed photograph 51. scim.ag/4rTKck8
scim.ag
How did Rosalind Franklin miss the helix in her iconic DNA image? She didn’t
New analysis refutes James Watson’s claim he was first to recognize significance of famed photograph 51
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Jeff Lange @jeffjlange.bsky.social · 30/07/2026
Drosophila stem cells can count! Super cool!
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Reposted by Jeff Lange
Carl Zimmer @carlzimmer.com · 22/07/2026
Did Thoreau encounter contagious cancer? A new study finds transmissible tumors in catfish--and raises questions about whether they could arise in humans someday. Gift link: nyti.ms/4whfi6v
nyti.ms
Deep in This Lake, a Contagious Cancer Is Spreading (Gift Article)
Transmissible tumors have been reported in a handful of animal species, but never before among fish. Is it possible in humans?
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Jeff Lange @jeffjlange.bsky.social · 15/06/2026
You might call them fire flies, but I call them lightning bugs, either way there's a whole lot of them!
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Jeff Lange @jeffjlange.bsky.social · 04/06/2026
Has anyone observed mNeonGreen getting brighter after photobleaching?
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Reposted by Jeff Lange
Sarah Gilmour @sarahgilmour.bsky.social · 13/05/2026
🚨Preprint alert! If you you’ve been following the centromere field recently, you’ve seen some (excellent) work showing that repeat copy number is highly variable in centromere region leading to massive variation in size. Here we try to understand how that variation impacts centromere functionality:
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Reposted by Jeff Lange
bioRxiv Genetics @biorxiv-genetic.bsky.social · 12/05/2026
Pericentromeric repeat copy number tunes heterochromatin dosage to control chromosome segregation and gene expression in fission yeast www.biorxiv.org/content/10.64898/20…
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Jeff Lange @jeffjlange.bsky.social · 01/05/2026
pmc.ncbi.nlm.nih.gov/articles/PMC... Researchers are exploring the possibility that eating a "false morel" that generates a toxin (gyromitrin) gave rise to a cluster of ALS cases in a small town in the French Alps. This paper specifically identifies the mushrooms. G. venenata and G. esculenta.
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Reposted by Jeff Lange
Gummy Arts @gummyarts.bsky.social · 22/04/2026
Earth, 2026 Topps style, based on recent Artemis II images #EarthDay
Colored-pencil card drawing of Earth, based on the “Earthset” photo taken by Artemis II astronaut Christina Koch
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Jeff Lange @jeffjlange.bsky.social · 13/03/2026
Has anyone tried Solid Phase MicroExtraction (SPME) for lipids analysis? If so, what kind of SPME fiber did you use?
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Reposted by Jeff Lange
Liyang Shi @liyangshi.bsky.social · 31/01/2026
Transposable elements determine 3D genome organization—beyond CTCF binding #TEsky link.springer.com/article/10.1...
link.springer.com
Dissecting the contribution of transposable elements to interphase chromosome structure - Genome Biology
Background Transposable elements (TEs) occupy nearly half of the human genome and play diverse biological roles. Despite their abundance, the extent to which TEs contribute to three-dimensional (3D) g...
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Reposted by Jeff Lange
Changyang Linghu @changyanglinghu.bsky.social · 26/01/2026
Our CytoTape work is published today in Nature @nature.com! CytoTape is a genetically encoded, flexible, intracellular protein tape recorder for spatiotemporally scalable and multiplexed recording of cellular activities continuously across weeks in vitro and in vivo. www.nature.com/articles/s41...
CytoTape in a neuron
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Reposted by Jeff Lange
Stowers Grad School @stowersgrad.bsky.social · 14/01/2026
🚨 Last chance to apply! 🚨Applications for the 2026 Summer Scholars Program close this Friday, 1/16. Spend 8 weeks doing hands-on #research in a world-class lab. 📽️⬇️Hear from former Summer Scholars + APPLY now → bit.ly/3SDVdGo
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Reposted by Jeff Lange
Stowers Grad School @stowersgrad.bsky.social · 26/11/2025
⏰ Final call! Applications for our #PhD program close December 1. Don’t miss your chance to train with world-class scientists in an independently fully funded program. #GradSchool Apply today → bit.ly/44VM6DI
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Jeff Lange @jeffjlange.bsky.social · 24/11/2025
Several years ago I switched to drinking mostly decaf coffee. I still have a single cup of regular per day, but decaf is part of life now. I went to a coffee shop to do some work and I ordered a decaf carmel latte. This did not go according to plan...
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Reposted by Jeff Lange
Jeremy Berg @jeremymberg.bsky.social · 21/11/2025
My quote of the day You build on failure. You use it as a stepping stone. Close the door on the past. You don't try to forget the mistakes, but you don't dwell on it. You don't let it have any of your energy, or any of your time, or any of your space. Johnny Cash
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Reposted by Jeff Lange
Irina Bezsonova @irinabezsonova.bsky.social · 06/10/2025
This October I’m drawing 1 molecule a day inspired by proteins in pdb @rcsbpdb.bsky.social Day 5 Prompt DEER Pdb 4YXH Two molecules of a deer prion protein decorate its head. Misfolded prions can make other prions to misfold causing neurodegenerative diseases in mammals. Next: PIERCE Suggestions?
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Jeff Lange @jeffjlange.bsky.social · 05/11/2025
I don't use AI on an everyday basis or nearly at all. I have been looking for a paper which I remember that showed expansion of bio samples so large that they are visible to the naked eye. I asked copilot and it found it immediately. It even gave me a real link that worked. I am devastated.
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Reposted by Jeff Lange
Stowers Grad School @stowersgrad.bsky.social · 25/10/2025
What makes #StowersGrad distinct from other #PhD programs? Our students are not limited to only learning under their PI. Experts throughout the Institute in our 16 Technology Centers offer additional learning opportunities. Learn more + apply now: bit.ly/44VM6DI
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Reposted by Jeff Lange
Stowers Institute @stowersinstitute.bsky.social · 20/10/2025
A new @sciam.bsky.social feature explores #research from the Halfmann Lab, revealing that our cells contain immune proteins that can instantly form crystals—triggering the cell to sacrifice itself when a virus invades. #SciSky 🔗 Read here: www.scientificamerican.com/article/cell...
scientificamerican.com
Cells Have a Death Switch That Protects Us from Viruses but Also Leads to Aging
A special class of immune proteins protect us from pathogens but also drive inflammation and cell death
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Jeff Lange @jeffjlange.bsky.social · 16/10/2025
It's always funny to see these. The bar for effort on these type emails is so low. I believe in you, you can do it.
An image showing a salutation from an email I received that says "Dear Jeffrey," followed by "Dear [First Name],"
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Jeff Lange @jeffjlange.bsky.social · 10/10/2025
Has anyone tried using mesoscope.scripps.edu/beta/index.h... and CellPAINT2D to try to illustrate/simulate phase separation? You can make multivalent interactions, but they don't unbind, at least that I can figure out.
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Reposted by Jeff Lange
Stowers Institute @stowersinstitute.bsky.social · 11/09/2025
This week is #CRC25 — our annual Crossroads Research Conference! A time for our community to connect, share discoveries, and spark new collaborations. Hear from attendees including @jeffjlange.bsky.social & @juliannahaug.bsky.social ⬇️
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Reposted by Jeff Lange
Stowers Grad School @stowersgrad.bsky.social · 08/09/2025
Applications for our #PhD program are NOW OPEN! Our independently fully funded program allows students to focus entirely on #research & growth, exploring their own questions while learning from top experts in the field. #GradSchool Apply now: bit.ly/44VM6DI
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Reposted by Jeff Lange
Matt Gibson @mgstowers.bsky.social · 14/08/2025
Cnidarian-Microbe Interactions Fully-funded postdoctoral position is available in the Gibson Lab at the Stowers Institute to investigate any aspect of cnidarian-microbe interactions. Strong background in coral symbiosis or eukaryotic microbiology preferred. Contact Matt Gibson: mg2@stowers.org
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Jeff Lange @jeffjlange.bsky.social · 29/08/2025
A little Friday distraction, is the sound a Mac plays when you turn it on the final chord from A Day in the Life by the Beatles? This is a clip of the song in question. youtube.com/clip/UgkxZZ3...
youtube.com
YouTube
Share your videos with friends, family, and the world
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Jeff Lange @jeffjlange.bsky.social · 08/06/2025
Sweet! Very excited to read this paper on the transcriptome AND proteome of stress granules both from yeast and mammalian after treatment with azide/arsenite. www.cell.com/cell-reports... I've always wondered if the contents are there by accident, or on purpose to maintain the phase/granule.
cell.com
Large-scale purifications reveal yeast and human stress granule cores are heterogeneous particles with complex transcriptomes and proteomes
Demeshkina and Ferré-D'Amaré purify stress granule cores from yeast and mammalian cells. These cytoplasmic ribonucleoproteins are a conserved response of eukaryotic cells to stressors; their dysregula...
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Reposted by Jeff Lange
Stowers Grad School @stowersgrad.bsky.social · 05/05/2025
Today we celebrate the accomplishments of our 2025 graduates! #GraduationDay #PhD
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Jeff Lange @jeffjlange.bsky.social · 03/05/2025
It's a beautiful day for disc golf!
A beautiful blue sky with a few puffy clouds above a disc golf tee pad which faces a few trees in the fairway with trees lining the far away landscape.
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Reposted by Jeff Lange
Stowers Institute @stowersinstitute.bsky.social · 07/03/2025
Meet Jeff Lange, Senior Research Scientist, in this #RoadToResearch Q&A! "I hope to inspire early-career researchers to be curious and, in turn, have a far-reaching impact on humanity and human health as a whole." Read more: bit.ly/3Fd0nVm
bit.ly
Road to Research: Q&A with Jeff Lange, Senior Research Scientist
"I hope to inspire early-career researchers to be curious and, in turn, have a far-reaching impact on humanity and human health as a whole."
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Reposted by Jeff Lange
Darren Thomson @darrenthomson.bsky.social · 03/01/2025
I'm looking to database organelle dyes which work in fungi. Please comment if you can contribute w/ details. We regularly see @mrccmm.bsky.social that some don't work in some fungi, but I just don't think it's been tested properly #Mycoscopy I started this w/ Alex Lichius years ago, tip of the 🧊!
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Reposted by Jeff Lange
Stowers Institute @stowersinstitute.bsky.social · 04/02/2025
The Institute mourns the loss of R. Scott Hawley, PhD. A brilliant scientist, cherished colleague, and true mentor. Scott's contributions to our understanding of genetics and passion for training the next generation of scientists will forever be remembered. bit.ly/3WPqqYG
bit.ly
Remembering R. Scott Hawley, Ph.D.
A Legacy of Scientific Excellence and Mentorship
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Jeff Lange @jeffjlange.bsky.social · 25/01/2025
Deleting my 20 year old Facebook account. It's harder to do it than I thought it would be. I originally joined earlier than that when my University became eligible to join. But I nuked that first profile in 2004. Downloading your data takes time...plan ahead.
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Jeff Lange @jeffjlange.bsky.social · 03/01/2025
Here's a way to brighten up your Friday! The manatees are back in Florida for the winter and that means you get to watch them on live webcam feeds. savethemanatee.org/manatees/web... Enjoy!
savethemanatee.org
Webcams | Save the Manatee Club
Manatee webcams offer live footage of these gentle giants in their natural habitat, both above-water and underwater. Watch now!
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Jeff Lange @jeffjlange.bsky.social · 30/12/2024
Up for the sunrise this morning and it did not disappoint!
Picture showing the sunrise this morning. The sky is painted in red, orange, yellow and dark blue with the dark landscape at the bottom.
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Jeff Lange @jeffjlange.bsky.social · 21/11/2024
Working on our first attempt at ONE microscopy today. www.nature.com/articles/s41... Very exciting!
nature.com
One-step nanoscale expansion microscopy reveals individual protein shapes - Nature Biotechnology
Combining expansion microscopy with super-resolution radial fluctuations captures the morphology of single proteins.
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Jeff Lange @jeffjlange.bsky.social · 15/11/2024
Fluorescence Friday huh? How about this wild spindle from Xenopus tissue culture cells? This was taken last week during out Cell Biology grad module. I'll try posting a video in the comments to this post. I tried an animated gif already and it didn't seem to work.
An image showing a triple spindle during mitosis from a binucleated cell in a Xenopus tissue culture system.
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Reposted by Jeff Lange
zack chiang @zchiang.bsky.social · 11/11/2024
7 years ago, I met a junior fellow named Jason Buenrostro who blew me away with a vision of futuristic genomic technologies Today, we (Ajay Labade, Caroline Comenho) are excited to share our first steps into that future: Expansion in situ genome sequencing 1/
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Jeff Lange @jeffjlange.bsky.social · 11/11/2024
Gonna send this out there one more time since there are so many new people here. Any info would be appreciated!
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Jeff Lange @jeffjlange.bsky.social · 10/11/2024
This is pretty epic!
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Jeff Lange @jeffjlange.bsky.social · 07/11/2024
Has anyone been to the American Physical Society's March meeting (now apparently called the APS Global Physics Summit) specifically looking for biophys content? How does it compare the Biophysical Society conference? Or how does it compare to other large meetings (ASCB, SFN, ?) you may have been to?
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Reposted by Jeff Lange
Beth Cimini 🔬💻📊 @bethcimini.bsky.social · 06/11/2024
Made a starter pack for microscopy and image analysis - please (self-)nominate additions! go.bsky.app/Nwa91pC
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Jeff Lange @jeffjlange.bsky.social · 31/10/2024
Pretty good pumpkins from the kiddos this year! Happy Halloween!
A carved pumpkin showing the sand worm from BeetlejuiceA carved pumpkin showing Linus from It's the Great Pumpkin Charlie Brown when he gets a rock.
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Reposted by Jeff Lange
Matthias Nau @matthiasnau.bsky.social · 30/10/2024
Want to make beautiful scientific figures? Easy! The NIH released a library of 2000+ free scientific illustrations called *BioArt*. Check it out! bioart.niaid.nih.gov #AcademicSky #PsychSciSky 🧠🟦 🧪
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Gummy Arts @gummyarts.bsky.social · 28/10/2024
Polio vaccine pioneer Jonas Salk, born on this date in 1914
Colored-pencil card drawing of Jonas Salk
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Jeff Lange @jeffjlange.bsky.social · 23/10/2024
I voted! Can the ads please stop now!?
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Jeff Lange @jeffjlange.bsky.social · 17/10/2024
Doing a journal club on this paper this morning: www.nature.com/articles/s41... I'm excited to get into it!
nature.com
One-step nanoscale expansion microscopy reveals individual protein shapes - Nature Biotechnology
Combining expansion microscopy with super-resolution radial fluctuations captures the morphology of single proteins.
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Jeff Lange @jeffjlange.bsky.social · 16/10/2024
We were able to find the comet tonight! Google Pixel camera FTW!
Picture showing the comet Atlas with streaked out tail lights of cars on the highway below.
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Jeff Lange @jeffjlange.bsky.social · 09/10/2024
Now that Twitter for me is gone for good, can we please get the National Weather Service regional accounts moved over here? That's one thing I definitely miss about Twitter.
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Jeff Lange @jeffjlange.bsky.social · 09/10/2024
I haven't posted there in almost a year, but today it's official.
Twitter icon showing my old account is deactivated.
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