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Changyang Linghu

@changyanglinghu.bsky.social
146 followers 282 following 24 posts

Assistant Professor at UMich, PhD at MIT, NIH Director's New Innovator Awardee, MIT Technology Review's Innovator Under 35, www.spatialbiodynamics.org

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Changyang Linghu @changyanglinghu.bsky.social · 23/06/2026
What if you could record cytosolic activities or archive proteins on an intracellular tape across time? 📼 Introducing: 🔍 CytoSense records protease & kinase signaling activities 📦 CytoCatch archives cytosolic proteins along CytoTape Preprint: doi.org/10.64898/202... 🧵Thread (1/7)
CyTRACE schematic - CytoSense and CytoCatch
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Changyang Linghu @changyanglinghu.bsky.social · 22/05/2026
Introducing GLOBE—a new technology for brain-wide, single-cell recording of cellular activity in vivo. GLOBE can continuously record from nearly a quarter million individual neurons simultaneously across a mouse brain. Preprint out on bioRxiv: doi.org/10.64898/202... 🧵(1/6)
Recording scalability in vivo
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Changyang Linghu @changyanglinghu.bsky.social · 26/01/2026
Our CytoTape work is published today in Nature @nature.com! CytoTape is a genetically encoded, flexible, intracellular protein tape recorder for spatiotemporally scalable and multiplexed recording of cellular activities continuously across weeks in vitro and in vivo. www.nature.com/articles/s41...
CytoTape in a neuron
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