Our newest study is now published. Here we show that GLP-1Rs are expressed in the lymphatic vasculature and enriched in LECs. And pharmacological activation by semaglutide enhances the pumping capacity of collectors.
onlinelibrary.wiley.com/doi/10.1111/...
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GLP‐1 Receptors Are Enriched in the Lymphatic Endothelium and Their Pharmacological Activation With Semaglutide Improves the Pumping Capacity of Lymphatic Vessels
Objectives
Recent clinical studies have suggested that glucagon-like peptide-1 receptor (GLP-1R) agonists may be effective therapies to treat or reduce the risk of developing secondary lymphedema. I.....