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Mary Schulz

@maryschulz.bsky.social
51 followers 79 following 10 posts

PhD Candidate in @jcastorena.bsky.social Castorena Lab at Tulane BMS

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Mary Schulz @maryschulz.bsky.social · 24/06/2026
Excited to share that our recent paper showing GLP-1R agonism directly improves the pumping capacity of lymphatic vessels is featured on the journal cover! doi.org/10.1111/micc... @jcastorena.bsky.social
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Jorge Castorena @jcastorena.bsky.social · 05/06/2026
Our newest study is now published. Here we show that GLP-1Rs are expressed in the lymphatic vasculature and enriched in LECs. And pharmacological activation by semaglutide enhances the pumping capacity of collectors. onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
GLP‐1 Receptors Are Enriched in the Lymphatic Endothelium and Their Pharmacological Activation With Semaglutide Improves the Pumping Capacity of Lymphatic Vessels
Objectives Recent clinical studies have suggested that glucagon-like peptide-1 receptor (GLP-1R) agonists may be effective therapies to treat or reduce the risk of developing secondary lymphedema. I.....
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Mary Schulz @maryschulz.bsky.social · 06/03/2026
Had a wonderful time presenting our work, catching up with friends, and learning so much at #GRCLymphatics in Italy! @jcastorena.bsky.social
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bioRxiv Physiology @biorxiv-physio.bsky.social · 27/12/2025
GLP-1R Agonism Directly Improves the Pumping Capacity of Murine Collecting Lymphatic Vessels www.biorxiv.org/content/10.64898/20…
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Mary Schulz @maryschulz.bsky.social · 27/12/2025
Pumped to share our new preprint showing GLP-1R agonism directly improves lymphatic contractility!
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Jorge Castorena @jcastorena.bsky.social · 13/08/2025
Very proud of my student @maryschulz.bsky.social, who just received a NOA for her NIH-F31 project to study obesity-induced lymphatic dysfunction and explore novel therapeutics. Also, her recent paper (www.ahajournals.org/doi/10.1161/...), has been highlighted by an Editorial at ATVB. Congrats, Mary!
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Hao Yin @haoyin.bsky.social · 19/06/2025
scRNAseq of🐭collecting lymphatic vessels😎 Cell type-specific #LymphaticEndothelialCell vs peri-lymphatic myeloid cell contributions of TRPV4 in distinct stages of lymphatic contractile activity @maryschulz.bsky.social @jcastorena.bsky.social #ATVB 2025 www.ahajournals.org/doi/full/10....
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Mary Schulz @maryschulz.bsky.social · 15/06/2025
Grateful for the opportunity to present our research at #LymphaticForum2025 in Chicago and learn about all the cutting edge research in lymphatics! Special thanks to LE&RN for the travel award! @jcastorena.bsky.social
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Mary Schulz @maryschulz.bsky.social · 02/06/2025
Excited to share our work on TRPV4 channels in lymphatic contractile function! www.ahajournals.org/doi/10.1161/... @jcastorena.bsky.social @ahajournals.bsky.social @ahascience.bsky.social
ahajournals.org
Regulation of Collecting Lymphatic Vessel Contractile Function by TRPV4 Channels | Arteriosclerosis, Thrombosis, and Vascular Biology
BACKGROUND: Dysregulation of TRPV4 (transient receptor potential vanilloid type 4)–mediated signaling has been associated with inflammation and tissue fibrosis, both of which are key features in the p...
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Jorge Castorena @jcastorena.bsky.social · 01/05/2025
Our study with Mike Davis showing that a component of the lymphatic contractile impairment in db/db mice is mediated by the activation of KATP channels in lymphatic muscle cells, in part due to chronic metabolic stress associated with elevated glucose, is now out. www.frontiersin.org/journals/phy...
frontiersin.org
Frontiers | Chronic metabolic stress impairs lymphatic contractility via activation of KATP channels in a mouse model of Type-2 diabetes
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Vincenza Cifarelli, PhD @cifarelliv.bsky.social · 12/03/2025
Our latest publication investigating the role of #palmitoylation in #lymphatic endothelial integrity. Big shoutout to Silvia Gonzalez-Nieves, Simon GUIGNARD and Thi Nguyen for their incredible work and dedication. 👏👏 www.sciencedirect.com/science/arti...
sciencedirect.com
Insulin regulates lymphatic endothelial integrity via palmitoylation
Lipid metabolism plays a critical role in lymphatic endothelial cell (LEC) development and vessel maintenance. Altered lipid metabolism is associated …
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Mary Schulz @maryschulz.bsky.social · 22/01/2025
Not science related, but had to document the monumental snowstorm that happened in NOLA yesterday! ❄️
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