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Brant Isakson

@brantisakson.bsky.social
236 followers 234 following 40 posts

How do cells in the microcirculation talk? That’s my jam. Also known as @conn_pann_fun on ol’ Twitter. I’ve been at UVA a lonnnnng time. ♥️🦕 physiology

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Reposted by Brant Isakson
Jonathan Jaggar @jaggarlab.bsky.social · 27/03/2026
Our review on Potassium Channels in Vascular Smooth Muscle Cells is out at Physiological Reviews. More than 150 pages long and citing more than 1500 articles, this herculean effort was co-authored by Tessa Garrud and Dan Collier. journals.physiology.org/doi/full/10....
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Reposted by Brant Isakson
UVA CVRC @uvacvrc.bsky.social · 11/07/2025
Why travel to Denmark to collect samples from a giraffe's heart? @brantisakson.bsky.social lab members Skylar Loeb and @lukedunaway.bsky.social made the trip to learn more about diastolic heart failure. Red more: www.cvrc.virginia.edu/cvrc-trainee... #cardiology #medsky
cvrc.virginia.edu
CVRC Trainees Travel Abroad to Collect a Giraffe Heart – Robert M. Berne Cardiovascular Research Center
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Reposted by Brant Isakson
Manuel F. Navedo @mfnavedo.bsky.social · 10/07/2025
Excited to pre-release the latest from the lab on how arterial myocyte Panx1 controls vascular reactivity in diabetes. Massive effort from the M&M Team in collaboration with @brantisakson.bsky.social and Xiang Lab
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Brant Isakson @brantisakson.bsky.social · 20/06/2025
Happy Donut Friday!
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Brant Isakson @brantisakson.bsky.social · 13/06/2025
Happy Donut Friday—Love the Cville Donut selections! 🍩
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Brant Isakson @brantisakson.bsky.social · 05/06/2025
🍷 Cheers C’ville! www.nytimes.com/2025/05/28/d...
nytimes.com
Virginia Is Finally for Wine Lovers
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Brant Isakson @brantisakson.bsky.social · 23/05/2025
TGIF!
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Brant Isakson @brantisakson.bsky.social · 23/05/2025
Happy Donut Friday to all that celebrate!
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Brant Isakson @brantisakson.bsky.social · 16/05/2025
Happy Donut Friday! Sbrocco’s for the win!
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Brant Isakson @brantisakson.bsky.social · 07/05/2025
Our first giraffe heart acquisition has caused an epic Isakson Lab Slack blowup this morning 🦒🦒
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Brant Isakson @brantisakson.bsky.social · 05/05/2025
Jammin’
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Brant Isakson @brantisakson.bsky.social · 30/04/2025
Guesses? Hint: not human/mouse/rat
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Reposted by Brant Isakson
Luke Dunaway @lukedunaway.bsky.social · 24/04/2025
Headed to #APS2025! Two great talks tomorrow from the Isakson Lab in the MCS session. Wyatt Shug (8:30AM) will present on basophil-endothelial crosstalk, and Skylar Loeb (10:50AM) will present the novel identification and impact of hemoglobin-alpha in cardiac lymphatics. @brantisakson.bsky.social
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Reposted by Brant Isakson
Stirling Churchman @stirlingchurchman.bsky.social · 21/04/2025
My father-in-law, Jack Strominger, and I wrote a letter to the @wsj.com editor about the current threats to science due to Trump's funding freeze. Please repost! www.wsj.com/opinion/scie...
wsj.com
Opinion | Science Suffers With Trump’s Funding Freeze
America’s scientific enterprise demands reliable stewardship, not destabilizing political intervention.
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Brant Isakson @brantisakson.bsky.social · 21/04/2025
Some of the strong work by Melissa Luse rounding her PhD. Love the story, and I think it opens up some new ideas in endothelial lipid handling and overall questions roles for NO… www.ahajournals.org/doi/10.1161/...
ahajournals.org
Nitrosation of CD36 Regulates Endothelial Function and Serum Lipids | Arteriosclerosis, Thrombosis, and Vascular Biology
BACKGROUND: During obesity, endothelial cells (ECs) become lipid laden, leading to endothelial dysfunction. We tested posttranslational modification on CD36 that may regulate EC lipid accumulation. ...
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Reposted by Brant Isakson
UVA CVRC @uvacvrc.bsky.social · 04/04/2025
Want to stay current with cardiology at UVA? Check out our starter pack! If you're a cardiologist at UVA and want to be included in the list, DM us! go.bsky.app/3NVEjJ5
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Brant Isakson @brantisakson.bsky.social · 30/03/2025
Lab outing, snuggling baby goats!🐐🐐
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Reposted by Brant Isakson
UVA CVRC @uvacvrc.bsky.social · 20/03/2025
@lukedunaway.bsky.social, PhD, recently received an @americanheart.bsky.social Career Development Award to study iron's role in chronic kidney disease. Luke is a postdoc in @brantisakson.bsky.social's Lab and member of our Cardiovascular Training Program. Congratulations! #CardioSky #MedSky
cvrc.virginia.edu
Luke Dunaway, PhD, Wins AHA Award for Chronic Kidney Disease Research – Robert M. Berne Cardiovascular Research Center
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Brant Isakson @brantisakson.bsky.social · 21/02/2025
Happy Donut Friday! C’ville’s very own Belle for the win…
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Brant Isakson @brantisakson.bsky.social · 07/02/2025
some good distraction tonight from the political crazies
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Brant Isakson @brantisakson.bsky.social · 07/02/2025
Happy Donut Friday!
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Brant Isakson @brantisakson.bsky.social · 31/01/2025
Happy Donut Friday!
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Reposted by Brant Isakson
ferrutxoart.bsky.social @ferrutxoart.bsky.social · 26/01/2025
Qunkasaura is the last dinosaur described in Spain, a large titanosaur that lived alongside Lohuecotitan at the Lo Hueco site, in the province of Cuenca #paleoart
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Brant Isakson @brantisakson.bsky.social · 17/01/2025
Happy donut Friday!🍩
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Brant Isakson @brantisakson.bsky.social · 07/01/2025
🦕🦕 I’m happy this fun little book is finally out exploring how the physiology of the sauropod dino helped contribute to its dominance on earth for so long. However, I think I’ll stick to my day job 😁 🦕🦕
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Brant Isakson @brantisakson.bsky.social · 20/12/2024
Happy Donut Friday to these three! Zuza received an AHA for work on Piezo2, Wyatt received BOTH an AHA and a F31 for work on basophils, and Skylar received an F31 for work on lymphatic alpha globin! Honored to have them in lab! (Pic from 2024 NAVBO)
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Brant Isakson @brantisakson.bsky.social · 18/12/2024
From our lab to yours, happy holidays!
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Brant Isakson @brantisakson.bsky.social · 13/12/2024
First “Happy Donut Friday” on Bluesky!
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Brant Isakson @brantisakson.bsky.social · 12/12/2024
Delighted to share ongoing translation of our discovery that alpha globin-eNOS is a potent regulator of NO in endothelium. In this work, the mechanism is confirmed in humans with alpha thalassemia, and our HbaX peptide used to dilate sickle cell arteries n/🧵 www.ahajournals.org/doi/abs/10.1...
ahajournals.org
Sickle Trait and Alpha Thalassemia Increase NOS-Dependent Vasodilation of Human Arteries Through Disruption of Endothelial Hemoglobin-eNOS Interactions | Circulation
BACKGROUND: Severe malaria is associated with impaired nitric oxide (NO) synthase (NOS)–dependent vasodilation, and reversal of this deficit improves survival in murine models. Malaria might have sele...
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Brant Isakson @brantisakson.bsky.social · 22/11/2024
1970s Chrome-plated sauropod 🦕
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Reposted by Brant Isakson
Timothy Hla @hlatim.bsky.social · 18/11/2024
Exciting Gordon conference on vascular cell biology - Jan 2025 in Ventura, CA org by Karen Hirschi, @UVA www.grc.org/vascular-cel...
grc.org
2025 Vascular Cell Biology Conference GRC
The 2025 Gordon Research Conference on Vascular Cell Biology will be held in Ventura, California. Apply today to reserve your spot.
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Brant Isakson @brantisakson.bsky.social · 06/11/2024
I’m finally migrating to bluer skies…
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