Reposted by NicDan O'Hara @skeuomorphology.bsky.social · 08/10/2026The PCR positivity map is out and the national average has risen again to 10.65% in England, 5.4% in Scotland. Scottish data is as of 4 days ago (Sunday); English data is as of 3 days ago (Monday). jamestindall.info/skeuomorphol... 1/8 36040
Reposted by NicAdam @abrokenbattery.bsky.social · 02/10/2026"This is the opposite of how science ought to work." George Monbiot on those pushing "false and dangerous" cures for #MECFS, "entrenched" in their beliefs and doubling down rather than admit the "great harm" to the lives of thousands of people. 512944
Reposted by NicDan O'Hara @skeuomorphology.bsky.social · 01/10/2026The PCR positivity map is out. Adjusted national positivity in England is up to 9.3%. We're still waiting for this week's Scottish data. I'll update the thread when it's out. jamestindall.info/skeuomorphol... 1/6 37935
Reposted by NicDan O'Hara @skeuomorphology.bsky.social · 22/09/2026Last time I posted this on here I got in bother Anyway, here's an update as of two days ago 1115
Reposted by NicLong Covid Kids @longcovidkids.bsky.social · 09/09/2026.🧵 1/7 When Long Covid affects a child’s education, attendance is only part of the story. As a new school year begins, new research looks beyond whether children are present in school, to learning, attention and friendships. #Education #InclusiveEducation #Attendance 22014
Reposted by NicDan O'Hara @skeuomorphology.bsky.social · 03/09/2026The PCR positivity map is out and positivity is up by just over a percentage point both in England and Scotland. These are the highest levels we've seen since November last year. The lull has been welcome, but it's over. jamestindall.info/skeuomorphol... 1/8 72316
Reposted by NicConor Browne @brownecfm.bsky.social · 25/08/2026I dislike sharing anecdotes, but I genuinely feel compelled to inform you all that in the past week I have found out that two more people I know have Long Covid, and that a family friend is still shielding. As you all know already, 'normality' is fundamentally a veneer. 1029266
Reposted by NicDan O'Hara @skeuomorphology.bsky.social · 27/08/2026The PCR positivity map is out. Unfortunately we're still waiting for the Scottish data, so here's an update for England only, where positivity has nudged up again. I'll add Scots data when we get it. jamestindall.info/skeuomorphol... 1/8 31610
Reposted by NicProf Cath Noakes @cathnoakes.bsky.social · 18/06/2025Warm nights and very hot days. Can be hard to stay cool especially in a city during a heatwave, but there’s some things you can do to help. 🧵1/ 11810
Reposted by NicEd Hutchinson @socialinfluenza.bsky.social · 07/05/2026🚨New paper!🚨 Our study showing that H5N1 influenza viruses can remain infectious in unpasteurised milk for, basically, as long as you are likely to encounter that milk has now been published: www.microbiologyresearch.org/content/jour... 28642
Reposted by NicChris Ponting @cgatist.bsky.social · 28/05/2026Important Long Covid findings suggesting "that approx 1 in 6 [US] patients with COVID-19 develops postacute sequelae, predominantly chronic conditions currently invisible to surveillance systems, representing an accumulating rather than resolving health care burden" jamanetwork.com/journals/jam...jamanetwork.comLong COVID Persistence and Surveillance Gaps Across 58 US HospitalsThis cohort study quantifies the gap between true postacute sequelae of SARS-CoV-2 burden and diagnostic code–based estimates, determines the proportion representing chronic disease, and characterizes... 12514
Reposted by NicAdam @abrokenbattery.bsky.social · 10/05/2026Update on Savannah: Cyclizine was restored 2 weeks after arriving in Devon, which immediately enabled her to start eating again. After nearly 3 months of “relentless agony and begging”, oxycodone injections were also restored to a level that controls her pain.gofundme.comDonate to #SevereMErgency:Save Savannah from dying inside NHS hospital, organized by Sam PearceVery Severe ME patient 23 year-old Savannah Victora-May is at … Sam Pearce needs your support for #SevereMErgency:Save Savannah from dying inside NHS hospital 12411
Reposted by NicConor Browne @brownecfm.bsky.social · 26/02/20261. '(Dr. Avindra) Nath is less cautious. Drawing on patterns he’s seen across autopsies, imaging studies and long-term clinical assessments, as well as population data showing elevated dementia risk after Covid, he’s convinced the virus can accelerate neurodegenerative... archive.is/2026.02.25-1...archive.is 19538
Reposted by NicLinsey Marr @linseymarr.bsky.social · 23/02/2026Our latest paper shows that most aerosol sampling methods may underestimate infectious virus in air. We observed 100x more infectious flu virus and SARS-CoV-2 if it deposited directly on cells (more realistic) rather than in liquid first and then transferred to cells. pubs.acs.org/doi/full/10....pubs.acs.orgLoss of Infectivity of Influenza Virus and SARS-CoV-2 during Aerosol SamplingOur understanding of transmission of influenza virus and other respiratory viruses is limited by the difficulty of detecting infectious viruses in aerosol particles. Most aerosol sampling methods are believed to contribute to virus inactivation, but the magnitude of this sampling artifact is unknown. To investigate this question, we aerosolized influenza A virus (IAV) and SARS-CoV-2 suspended in human saliva into a small chamber (3.7 L). Aerosols settled for 10 min onto either cells or a thin layer of liquid medium that was immediately transferred to cells for plaque assay. Aerosols that deposited directly onto cells led to the formation of 100× more plaque forming units (PFU) compared to aerosols that deposited first into liquid medium. Further experiments ruled out uneven aerosol distribution in the chamber or inefficient virus recovery as causes of this discrepancy. These findings indicate that aerosolized IAV and SARS-CoV-2 lost infectivity by approximately 2 log10 PFU within ∼10 min unless they attached to cells quickly. As natural infection via inhalation occurs by direct deposition of the virus onto cells, we hypothesize that sampling directly onto cells more accurately reflects the potential for exposure to lead to infection. 417877
Reposted by NicAdam @abrokenbattery.bsky.social · 19/02/2026Update on Savannah: They are now urgently seeking any UK doctors or hospitals willing to provide TPN and restart cyclizine. If no safe option is found, they are even considering treatment abroad. If you have suggestions, please fill in the form tally.so/r/81KxGOtally.soPlease share any trusted doctors for (very) severe pwME. UK or Western Europe. NHS or private.Made with Tally, the simplest way to create forms. 11611
Nic @janenico.bsky.social · 16/02/2026Savannah is facing severe neglect at Queen Elizabeth Hospital due to lack of proper care for her severe ME. I hope she can be moved to a hospice, a lack of training is no excuse for the shameful behaviour of the staff imvolved here gofund.me/9774c5fd2gofund.meDonate to #SevereMErgency:Save Savannah from dying inside NHS hospital, organized by Sam PearceVery Severe ME patient 23 year-old Savannah Victora-May is at … Sam Pearce needs your support for #SevereMErgency:Save Savannah from dying inside NHS hospital 000
Reposted by NicDan O'Hara @skeuomorphology.bsky.social · 12/02/2026The PCR positivity map is out, and positivity has risen to 2.75% in England. Adjusted for non-reporting we make it 3.34%. In Scotland there's been a sharp upturn to 4.37%. jamestindall.info/skeuomorphol... 1/9 11210
Reposted by NicME/CFS Science @mecfsscience.org · 15/12/20251) New factsheet: ME/CFS - information for medical professionals (6 pages). Written by Prof. Emeritus Jonathon Edwards and members of the Science for ME forum. A valuable text, useful to bookmark. A couple of quotes from key paragraphs 👇 13411
Reposted by NicConor Browne @brownecfm.bsky.social · 12/12/2025Delighted to have the opportunity to discuss the current influenza surge in today's Belfast Telegraph; the virus itself, what we should be doing to mitigate it - vaccination, ventilation, masks - and how infection control has become ideological. www.belfasttelegraph.co.uk/news/health/...belfasttelegraph.co.uk‘Not a pleasant Christmas for the NHS’: ‘Super flu’ mutation will further stress NI healthcare system, says biorisk expertThe early surge in a so-called ‘super flu’ strain of the influenza virus is going to “dramatically stress” the Northern Ireland healthcare service in the run-up to Christmas, a biorisk expert has said... 517266
Reposted by NicTrish Greenhalgh @trishgreenhalgh.bsky.social · 12/12/2025What Steve said. There has never been a study in which high-quality, well-fitting masks were actually WORN that did not show a significant impact on disease transmission. Many mask studies failed to take account of post-allocation confounders (non-adherence + non-mask people choosing to mask). 424991
Reposted by NicTrish Greenhalgh @trishgreenhalgh.bsky.social · 10/12/2025Should you wear a mask if you've got symptomatic flu? YES. If you wear it at home *from the onset of your symptoms*, your family members are much less likely to catch flu from you (but you must avoid unmasked co-sleeping and eating around same table - have your meals alone). 1/ 10510196
Reposted by NicConor Browne @brownecfm.bsky.social · 07/12/2025'Speaking on RTÉ's This Week, Mr Gloster* added that hospital emergency department attendance was at its "highest ever" last Monday' Highest ever. *The HSE Chief Executive. www.rte.ie/news/2025/12...rte.ieIMO warns that flu has hit Ireland 'fast and hard'The Irish Medical Organisation has warned that the flu has hit Ireland "fast and hard" and will add enormous strain to the already stretched public hospital system. 16936
Reposted by NicPaul Mainwood @paulmainwood.bsky.social · 02/12/2025So the flu peak was very temporary. Test numbers say influenza in the UK has just jumped back into huge growth this week: +76% up. Sustained, that would be very bad news. Measles cases have suddenly stepped up too. Don't like either of those. www.gov.uk/government/p...gov.ukNOIDs causative agents: week 48 (week ending 30 November 2025) 01711
Reposted by NicMike Honey @mikehoney.bsky.social · 02/12/2025Some concerning signals of a fresh wave of COVID in Germany, well after the earlier XFG.* peak. Could be seasonal factors, but that momentum shift looks too sharp IMO. The rise of BA.3.2.* is a possibility. Note the sequencing data lags by several weeks. threadreaderapp.com/thread/19947... 🧵threadreaderapp.comThread by @rv_enigma on Thread Reader App@rv_enigma: Covid-19 am 29.11.25: ↗️, 7TM~1000‼️ R_Berichte (FT-korr): 1,09 R_Meldungen (adj.) 1,11 R_Hospitalisierung: ↗️1,06 R_Meldungen(3 Wochen): 1,05 Verdopplungszeit: ~2 Monate Inkl. DZF 70: Fäl... 54615
Reposted by NicEsther @elhopkins.bsky.social · 02/12/2025www.dutchnews.nl/2025/12/eigh...dutchnews.nlEight kittens die of bird flu, pet owners warned to be alert - DutchNews.nlEight kittens in the Netherlands have died from bird flu, the first confirmed deaths among young animals, agriculture minister Femke Wiersma told MPs. The kittens were born on a goat farm and seven ha... 1104
Reposted by NicDenis - The COVID Info Guy @thecovidinfoguy.bsky.social · 29/11/2025"The problem with Long COVID is that most of society would rather not see it. We want to believe the pandemic was just a bad dream we awoke from years ago. (When I hear someone say during COVID, in the past tense, I want to flip a table.)" #LongCOVID Source: archive.md/7Rer1 322178
Reposted by NicConor Browne @brownecfm.bsky.social · 31/10/20251. I read a study that hinted at this over a year ago. Although the overall individual risk seems to be small, there will be impacts at the population level. The effects of pathogens are an inconvenient truth for MAHA. Non paywalled link in next post. www.washingtonpost.com/health/2025/...washingtonpost.comCovid in pregnancy tied to autism, developmental issues, study saysA study published in the journal Obstetrics and Gynecology analyzed more than 18,100 births in Massachusetts of children born to women who contracted the virus starting in the early months of the pand... 46228
Reposted by NicDr Satoshi Akima, FRACP @toshiakima.bsky.social · 24/10/2025Detection of Anti-SARS-CoV-2 Mucosal Immunoglobulin A in Clinical Saliva Samples After a Dose of Novavax COVID-19 Vaccineonlinelibrary.wiley.comDetection of Anti‐SARS‐CoV‐2 Mucosal Immunoglobulin A in Clinical Saliva Samples After a Dose of Novavax COVID‐19 VaccineImmunoglobulin (Ig) A acts as a first line of defense against respiratory pathogens. Mucosal IgA in salivary and nasal passages has a rapid response to antigens and can play a protective role against... 58022
Reposted by NicBinita Kane @binitakane.bsky.social · 12/10/2025We don’t fully understand what this means yet - but could be a marker on ongoing inflammation and endothelial damage, which is a precursor to cardiovascular disease. 0143
Reposted by NicBinita Kane @binitakane.bsky.social · 11/10/2025**PREPRINT** from Harvard & Massachusetts General - children with Long COVID show markedly increased levels of fibrinaloid microclots in their blood. The highest levels appear in those with persistent SARS-CoV-2 spike protein in circulation. www.researchsquare.com/article/rs-7...researchsquare.comQuantification of fibrinaloid clots in plasma from pediatric Long COVID patients using a microfluidic assayLong COVID (LC) impacts one in five children after an acute SARS-CoV-2 infection. Typical LC symptoms include fatigue, brain fog, pain, and shortness of breath, which can significantly impact individu... 410442
Reposted by NicME/CFS Science @mecfsscience.org · 03/10/20251) 🇳🇴 Ola Didrik Saugstad and his colleagues report about the first specialised care unit for severely and very severely affected ME/CFS patients. It opened in 2021 in Norway. The authors report the results from the first 3 years. 12411
Reposted by NicDan O'Hara @skeuomorphology.bsky.social · 02/10/2025The PCR positivity map is out, and it's evident that everywhere is seeing a significant surge. UKHSA positivity has risen to 11.83%. Adjusted for non-reporting areas, we make that 13.77%. jamestindall.info/skeuomorphol... 1/8 32824
Reposted by NicConor Browne @brownecfm.bsky.social · 19/09/2025Fundamentally, the reason I avoid Covid is because all - all - of the elements of my life that bring me joy and fulfillment rest on my cardiovascular fitness and / or my cognition. I'm not going to risk a virus wrecking that, as I've seen happen to way too many people I know. 4453131
Reposted by NicConor Browne @brownecfm.bsky.social · 16/09/20251. Pandemics shape politics and societies. Collective trauma is a powerful force, as is societal reaction to governmental responses to reduce transmission. This is not controversial; humanity experienced it after The Spanish Flu. 212235
Reposted by NicLinsey Marr @linseymarr.bsky.social · 14/09/2025GIFTED, UNLOCKED ARTICLE: www.wsj.com/business/air... with expert input from @joeallenjoe.bsky.social This is disturbing. I'm considering adding a respirator with activated carbon to my travel kit.wsj.comToxic Fumes Are Leaking Into Airplanes, Sickening Crews and PassengersDoctors compare brain effects to concussions in NFL players. A Wall Street Journal investigation shows such incidents are increasingly common. 77429
Reposted by Nicsarah boothby @swastrosarah.bsky.social · 08/09/2025as her advocates. As a reg SW, I have emailed to share PFD report, NHS Devon clinical guidance, and newly published NHS e-Learning module 3: a lot to digest for any busy hospital. As yet no invitation to join Zoom or MSTeams meeting. #pwME, please post support to Savannah. She is afraid for her life 0248
Reposted by Nicsarah boothby @swastrosarah.bsky.social · 08/09/2025🧵 Savannah update - please share widely. Formerly known as Gigi, Savannah (S) is in Room 4, Ward 1, Queen Elizabeth Hospital, Woolwich with very severe ME. All her energy is being spent on calling for help. There is a virtual MDT 10.30 tomorrow. S has asked that Dr Weir and I be invited to join 1/2 13620
Reposted by NicConor Browne @brownecfm.bsky.social · 07/09/2025The mindset that drives me to avoid Covid is exactly the same mindset that has kept me sober for over 18 years: recognition of the dangers of normalisation and complacency, a desire to optimise my health, and knowing that fleeting doubts are easily quashed by seeing consequences. 620740
Reposted by NicDan O'Hara @skeuomorphology.bsky.social · 04/09/2025The PCR positivity map is out, and while things may have calmed a little in Cumbria, and in Devon, everywhere else looks to be rising. jamestindall.info/skeuomorphol... 1/7 21414
Reposted by NicLinsey Marr @linseymarr.bsky.social · 02/09/2025We have policies/laws/regulations to ensure that our food and water are clean and safe. Why not for air, too? Typical amounts taken in per day: food = 4 lb water = 3 lb air = 30 lb 2448114
Reposted by NicMike Honey @mikehoney.bsky.social · 23/08/2025Here's the latest variant picture for the United Kingdom, to early August. The XFG.* "Stratus" variant remained dominant, growing to 67%. NB.1.8.1 "Nimbus" fell to 15%. #COVID19 #UK #XFG #Stratus #NB_1_8_1 #Nimbus 🧵 1163
Reposted by NicME/CFS Science @mecfsscience.org · 24/08/20251) Very preliminary data but Dutch researchers report that antibodies of Long Covid patients caused more cultured muscles cells to die. 24119
Reposted by NicME/CFS Science @mecfsscience.org · 22/08/20251) Interesting presentation by Anouk Slaghekke at the 2025 Berlin conference. This Dutch team found that small blood vessels of patients with ME/CFS and Long Covid are clocked up with Collagen IV. 33719
Reposted by NicDan O'Hara @skeuomorphology.bsky.social · 21/08/2025There's a lot of low/no testing in and around London. But if we look at areas still doing good testing, like Thurrock, we see almost vertical spikes. 5/7 102
Reposted by NicDan O'Hara @skeuomorphology.bsky.social · 21/08/2025The PCR positivity map is out. National positivity has risen to 8.83% - but remember the data only goes up to the 15th, 7 days ago. Everywhere in orange or darker on the map is above that figure. jamestindall.info/skeuomorphol... 1/7 21010
Reposted by NicME/CFS Science @mecfsscience.org · 21/08/20251) In a new genetics project supported by @MEResearchUK, Dr Alkisti Manousaki from the University of Leicester will study X chromosome inactivation in ME/CFS. This could help clarify why females are approximately 4 times more likely to develop ME/CFS than males. 12910
Reposted by NicMiriam E. Tucker @miriametucker.bsky.social · 20/08/2025“What had once felt like a rare or niche diagnosis now seemed to be everywhere, impossible to ignore.” - Brittany Adler, MD, of Johns Hopkins, re post-infectious chronic illness that goes by many names but has no dedicated medical specialty. #POTS #MECFS www.medscape.com/viewarticle/...medscape.comWhere Is the Medical Home for Postinfectious Illness?A rheumatologist calls for greater awareness among her colleagues but also emphasizes that these patients require multidisciplinary care. 54025
Reposted by NicConor Browne @brownecfm.bsky.social · 19/08/2025With the caveat that the study this article is referencing is a preprint, a 35% risk increase for Long Covid following reinfection is both significant and concerning. The study also provides more evidence that vaccination reduces risk; it's worth reading in full. 311231
Reposted by NicDavid Tuller @davetuller1.bsky.social · 16/08/2025In a meta-analysis of Long COVID interventions, most RCTs included were at high risk of bias and the quality of evidence for outcomes measured was overwhelmingly of low or very-low quality. Yet authors claim "high-certainty" evidence for exercise interventions. Huh?? virology.ws/2025/08/16/t...virology.wsTrial By Error: Lancet Paper Claims "Exercise" Should be "Prioritized" in Long COVID Rehabilitation | Virology BlogBy David Tuller, DrPH Added: On X, @mecfsskeptic has posted a very useful thread explaining how loosely the investigators applied the meaning of "Long ... 3457
Reposted by NicMike Honey @mikehoney.bsky.social · 16/08/2025[heavy sigh] With the NB.1.8.1 "Nimbus" and XFG.* "Stratus" variants carving up dominance around the globe, it is time to ponder which variant might drive the next wave. The leading contenders at this point are PY.1.1.1 and XFV. #COVID19 #PY_1_1_1 #XFV 🧵 24918