Modeling the synovium on a chip for studying the interactions between lymphatic vasculature and synoviocytes in rheumatoid arthritis, Kraus, Samantha E, Cano, Issahy, Kim, Soo Jin, Lee, Esak

The lymphatic system—integral to fluid balance, immune surveillance, and lipid absorption—is frequently overlooked despite its vital roles. Traditional research modalities, including static two-dimens...

A new study revealed how a deadly form of pancreatic cancer enters the bloodstream, solving a long-standing mystery of how the disease spreads and identifying a promising target for therapy.

A Cornell-led study has revealed how a deadly form of pancreatic cancer enters the bloodstream, solving a long-standing mystery of how the disease spreads and identifying a promising target for therapy.

Seventy-four early-career engineers have been selected to participate in the 2025 The Grainger Foundation Frontiers of Engineering Symposium.

Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest cancers, and its rapid spread depends on tumor cells breaching blood vessels through a process called intravasation.

Breaching the vascular barrier is a critical step in pancreatic ductal adenocarcinoma (PDAC) metastasis, yet the mechanisms enabling this process remain incompletely understood. Transforming growth fa...

Research funded by the National Eye Institute has identified the signaling mechanism that triggers steroid-induced glaucoma by creating a 3D “eye-on-a-chip” platform that mimics the flow of ocular flu...

"Human eye lymphatics-on-a-chip” microphysiological system to understand glaucoma mechanisms.

Increased intraocular pressure due to decreased outflow of aqueous humor from the anterior chamber of the eye is a major risk factor for the development of glaucoma, a leading cause of blindness. A ne...

Lu et al. created a human ocular outflow on-chip, composed of 3D Schlemm’s canal endothelium surrounded by trabecular meshwork and draining interstitial fluid, revealing ALK5/VEGFC signaling as a ther...