Sign in

IGFL

@igflyon.bsky.social
673 followers 90 following 34 posts

A strong focus on integrative, organism-level research at the interfaces of evolution, development & integrative physiology studied in lots of model systems igfl.ens-lyon.fr

PostsRepliesMedia
IGFL @igflyon.bsky.social · 01/06/2026
🧠 IGFL External seminar | @dulaclab.bsky.social (Harvard/HHMI) deciphers the neural circuits underlying instinctive social behaviors (parenting, mating, aggression) and how the brain drives adaptive behavioral changes during sickness. What a treat! 🧠
Catherine Dulac presenting her work on social isolation
171
IGFL @igflyon.bsky.social · 17/02/2026
L’IGFL recrute un•e Professeur•e des Universités en biologie moléculaire (CNU 64), UCBL Lyon 1. Enseignement L2-M2 (Biochimie et Biologie Moléculaire) + projet en biologie moléculaire des eucaryotes au sein de l’IGFL. Détails: shorturl.at/K5Dno #Recrutement #BiologieMoleculaire
Annonce officielle de l’IGFL pour le recrutement du poste cité ci-dessus
068
IGFL @igflyon.bsky.social · 29/01/2026
IGFL external seminar Birds keep losing their penises, repeatedly. Not by chance. Anamaria Necsulea (LBBE Lyon) shows how changes in gene regulation and non-coding DNA drive convergent developmental loss of the male phallus across avian evolution.
White IGFL seminar flyer. Top left: IGFL logo in pink. Center top: title “External seminars – IGFL” above a stylized blue question mark. Speaker name: Anamaria Necsulea.
Laboratory of the speaker: Laboratoire de biométrie et biologie évolutive (LBBE, Lyon).
Invited by: Eglantine Heude.
Date: 29/01/2026.
Title: “Convergent evolution of genomes and phenotypes in birds.”

Abstract summarizes comparative and functional evolutionary genomics in birds, focusing on convergent phenotypic evolution. Main case study: repeated reduction or loss of the intermittent male phallus in multiple avian lineages. The work analyzes hundreds of bird genomes to identify parallel changes in protein-coding genes, non-coding regulatory elements, and gene expression associated with this developmental and evolutionary transition.

Bottom section: short CV detailing PhD (University of Lyon), postdoc in Lausanne, junior group leader at EPFL, and current CNRS researcher at LBBE studying evolution of gene regulation and phenotypes.
Right side: portrait photo of the speaker outdoors, smiling, short hair, wearing a dark top.
021
IGFL @igflyon.bsky.social · 23/06/2025
Excited to host Jean Livet (Institut de la Vision) at IGFL Lyon on June 30th! He’ll share how multicolor labeling and large-volume microscopy reveal the topography and topology of central sensory circuits. A must for connectomics fans! 🧠🔬✨
Flyer announcing a seminar by Jean Livet from the Institut de la Vision, hosted by Jonathan Enriquez at IGFL Lyon on June 30th, 2025. The talk is titled “Topography and topology in a central sensory neuronal projection.” The abstract explains that in the vertebrate brain, sensory pathways connect neuronal relays with high precision over long distances. To study these circuits, dense single-neuron tracing and large-volume microscopy are used. Jean Livet will discuss their efforts in connectomic mapping using multicolor labeling, focusing on an auditory relay to reveal its topographical and topological organization. The flyer also includes a short bio: Jean Livet completed his PhD on motor neuron development at IBDM Marseille, developed the Brainbow labeling method during his postdoc with Jeff W. Lichtman in the USA, and has led the “neurogenesis and circuit development” team at the Institut de la Vision since 2008.
010
IGFL @igflyon.bsky.social · 02/06/2025
🦋 Butterflies and beyond! Steven Van Belleghem is now at IGFL revealing how genomes evolve into pangenomes, shaping adaptation and gene regulation in butterflies and Daphnia. Don’t miss this dive into the mysteries of evolution! #EvolutionaryGenomics
Cartoon of Steven Van Belleghem riding a giant beetle over green islands, holding a camera and flying scientific papers. A hawk and butterfly accompany him, symbolizing his evolutionary genomics research on butterflies, Daphnia, and beetles.
010
IGFL @igflyon.bsky.social · 16/05/2025
🧬 From genomes to pangenomes to adaptation! Join us June 2 at 11am in Salle des Thèses (IGFL) for Steven Van Belleghem’s talk on how structural genome variation and regulatory elements drive evolution—featuring butterflies, beetles, and Daphnia. 🦋🪲🦐
001
IGFL @igflyon.bsky.social · 05/05/2025
Live now at IGFL: Laure Bally-Cuif (Institut Pasteur) is sharing her fascinating work on the heterogeneity of adult neural stem cells. A deep dive into brain plasticity in action! #Neuroscience #IGFL #StemCells @zenlabpasteur.bsky.social
050
IGFL @igflyon.bsky.social · 25/04/2025
🧠 Seminar alert! Laure Bally-Cuif (Pasteur Institute) will present: "Individual cell heterogeneities and population dynamics for adult neural stem cell maintenance" She will show how neural stem cell sub-populations sustain neurogenesis in zebrafish. 📅 05/05/25, 11am, Salle Condorcet ENS Lyon
141
IGFL @igflyon.bsky.social · 07/04/2025
Time to go mad! Thank you @zaycha.bsky.social for inviting @mads100tist.bsky.social for exciting science on somatosensory neuron diversity.
0153
IGFL @igflyon.bsky.social · 01/04/2025
IGFL will be going mad next Monday, when we host @mads100tist.bsky.social, directly from Basel! We are looking forward to hearing an exciting talk!
172
IGFL @igflyon.bsky.social · 17/03/2025
Guest lecture today on Drosophila brain metabolism. Exciting results by Prof. Stefanie Schirmeier from TU Dresden.
The drosophila brain
030
IGFL @igflyon.bsky.social · 13/03/2025
Seminar alert! 🧠🔬 Prof. Stefanie Schirmeier (TU Dresden) presents "Metabolic flexibility of the Drosophila nervous system" on March 17th, 11 am at Salle Condorcet. Explore glial cells & adaptive metabolism! #Neuroscience #Metabolism
Title of the presentation
Metabolic flexibility of the Drosophila nervous system
Short abstract
Neuronal function consumes large amounts of energy. This energy needs to be provided in order to maintain homeostasis. To deal with this disproportionate demand, glial cells support neurons metabolically. Like their mammalian counterparts, Drosophila glial cells are very glycolytically active and provide lactate to the neurons under optimal conditions. Upon suboptimal conditions, several aspects of brain metabolism can be adapted. On the one hand, nutrient uptake into the nervous system is regulated to ensure nervous system function. On the other hand, glial cellular metabolism can adapt to changing conditions. E.g. when carbohydrate supply is not sufficient to meet the metabolic needs of the neurons, the glial cells switch to ß-oxidation of fatty acids and produce ketone bodies as an alternate fuel that they supply to neurons. It turns out that glial metabolism can be adapted to different conditions, like starvation or cold exposure, in different ways to ensure neuronal function.
Short CV
Stefanie Schirmeier graduated from the University of Bayreuth (Germany) and joined Dominique Ferrandon’s team at the University of Strasbourg (France), where she studied host-pathogen interactions using Drosophila melanogaster as a model. She contributed to a genome-wide genetic screen and discovered the compensatory proliferation of intestinal stem cells in response to gut infection, as well as identifying a bacterial virulence factor required to counteract the cellular immune response.
She then moved to the University of Münster (Germany) for a postdoctoral position, joining Christian Klämbt’s team and later establishing her own research group there. Stefanie focused on investigating the physiology and metabolism of glial cells and uncovered their role in neuronal nutritional support via the astrocyte-neuron lactate shuttle.
Since 2021, Stefanie has been a professor at Dresden Technic…
053
IGFL @igflyon.bsky.social · 10/01/2025
🌱 New findings on kelp zygotes! Bénédicte Charrier’s team shows how alginate forms a corset, shaping early cell fate. 🔬 Read the Scientific Reports paper: www.nature.com/articles/s41... 🖼️ Kelp zygote: alginate corset (green), nucleus (blue), chloroplasts (red). Length: 30 µm.
020
IGFL @igflyon.bsky.social · 26/11/2024
Congratulations @francoisleulier.bsky.social, recipient of the Jaffé Prize - Fondation de l'Institut de France. This award honors work or experiences aimed at advancing progress and the well-being of humanity.
4153
IGFL @igflyon.bsky.social · 07/02/2024
Poste d'IE à pourvoir dans l'équipe "Physiologie intégrative des interactions hôte/microbes". Les candidatures sont à déposer exclusivement sur le portail emploi du CNRS.
Poste à pourvoir d'IE en microscopie et immunohistochimie à l'IGFL. Plus d'infos: filipe.de_vadder@ens-lyon.fr.
004
IGFL @igflyon.bsky.social · 20/01/2024
Nous recrutons un•e assistant•e de direction. Les candidatures sont à envoyer à direction.igfl@ens-lyon.fr.
Poste d’attaché•e de direction à l’IGFL. Pour plus d’informations contactez direction.igfl@ens-lyon.fr.
001
IGFL @igflyon.bsky.social · 04/01/2024
On January 20th, IGFL will open its doors to present several marine model organisms igfl.ens-lyon.fr/news/de-l-oc...
De l'océan au laboratoire: à la rencontre des organismes modèles marins
036
IGFL @igflyon.bsky.social · 04/01/2024
The Spatial-Cell-ID team is hiring a postdoc or research engineer in image analysis applied to spatial transcriptomics
000