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Institute of Developmental & Regenerative Medicine

@idrm.ox.ac.uk
328 followers 82 following 105 posts

The Institute of Developmental & Regenerative Medicine combines cardiovascular science, neuroscience and immunology to develop new drugs and therapies.

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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 17/07/2026
The Oxford-ZEISS Centre of Excellence in Biomedical Imaging between @kiroxford.bsky.social and the Institute of Developmental & Regenerative Medicine has become the first to acquire the new ZEISS Lightfield 4D system. Read more: www.idrm.ox.ac.uk/news-and-fea...
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 24/06/2026
We were delighted to bring colleagues together to celebrate Prof Paul Riley's election to the Fellowship of the Royal Society. In true IDRM fashion, Paul used the occasion to recognise the many researchers, collaborators and colleagues who have contributed to the Institute's success.
Scientists gathered at the IDRM cafe to celebrate. Many people with their backs to the camera.Left to right, Prof Matthew Wood, Prof Paul Riley, and Prof Carlo Rinaldi smile at the camera.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 09/06/2026
In a new expert commentary, Associate Professor Thomas Roberts discusses a paper published in Gene Therapy, which examines the progress and challenges of AAV microdystrophin gene replacement therapies for #DuchenneMuscularDystrophy. Read more: tinyurl.com/2rzbyv6s
A scientist looking through a microscope with labe equipment around her
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 27/05/2026
We are excited to share that Professor Paul Riley has been elected to the Fellowship of the Royal Society, the UK’s national academy of sciences, for his outstanding contribution to regenerative medicine and cardiovascular science. www.idrm.ox.ac.uk/news-and-fea... @oxforddpag.bsky.social
Professor Riley is facing forward and smiling at the camera with a blurred building in the background. A red banner beneath his headshot reads 'Professor Paul Riley Royal Society Fellow'. The IDRM and University of Oxford logos appear at the bottom in white against a dark blue background.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 14/04/2026
The Oxford-ZEISS CoE in Biomedical Imaging, between the IDRM and @kiroxford.bsky.social at @ox.ac.uk, in collaboration with @zeiss-microscopy.bsky.social, is developing a new cutting-edge imaging technology: Selective Plane Illumination Lattice Light Sheet Microscopy. 🔗https://tinyurl.com/mu6xvpwc
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 26/03/2026
📢Exciting opportunity for postdocs! The IDRM is offering a Transition Fellowship for outstanding researchers at an intermediate/career development stage. Apply now: lnkd.in/eYkYUAhB #FellowshipOpportunity #Postdoc #InterdisciplinaryResearch @paediatrics.ox.ac.uk
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 18/03/2026
Spring has arrived at the IDRM! As research in developmental biology and regenerative medicine pushes boundaries within IDRM's laboratories, our scientists can take a look outside and enjoy the view of the blossoming trees in our Japanese garden. 🌸 @ox.ac.uk
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 10/03/2026
New research from the Roberts Group @ribomedicine.bsky.social at IDRM explores a new way to increase the body’s own production of BDNF, a key brain protein involved in neuron health, learning and memory. Read the paper: tinyurl.com/ydwxk49d
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 25/02/2026
Spring has arrived at the IDRM just in time for Green Action Week! We are taking action by promoting our book swap, recycling, and Beauty Banks sustainable initiatives. Our bug houses made for pollinators are spring-ready too — with a ladybird already spotted 🐞 #GreenActionWeek #Sustainability
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 11/02/2026
International Women and Girls in Science Day 👩‍🔬✨ We’re proud to support brilliant women at the IDRM, including Dr Andia Redpath, Dr Inhye Park, Dr Sophie Payne and Dr Susann Bruche, who recently took part in the EMBO Laboratory Leadership Course. Read more 👉 tinyurl.com/mrxurm52
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 16/01/2026
In December, we hosted the EMBO Lab Leadership Course with NDM and the Dunn School of Pathology. We spoke to Dr Sophie Payne, Dr Susann Bruche, Dr Inhye Park and Dr Andia Redpath about what they learned about leadership and leading their own research teams. Read more: tinyurl.com/mrxurm52
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 16/12/2025
This week’s scientific image, submitted by the Holländer Lab, is titled “The birth of immunity: spatial transcriptomics illuminating the thymus at E14.5.” The image uses spatial transcriptomics to visualise gene expression patterns across the embryonic thymus at day 14.5.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 11/12/2025
This week’s scientific image, created by Ehsan Razaghi, DPhil student, Simões lab, is titled “Immune-mediated spatial orchestration of cardiac regeneration in zebrafish, 5 days post cryoinjury.” His research focuses on the role of the immune system in heart regeneration after myocardial infarction.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 10/12/2025
A huge congratulations to Joe Day, former Communications & Operations Apprentice and current Business Development & Engagement Officer at the IDRM, on winning the Shining Star Apprentice Award at the 2025 University of Oxford Apprenticeship Awards!
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 04/12/2025
This week’s scientific image, contributed by Dr Emma Haberman from the Riley and Holländer groups, is titled “Atrial Architecture.” Her work investigates the role of T cell-mediated autoimmunity in the progression of heart failure after myocardial infarction.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 28/11/2025
New from Dr Matthew Stower and the Srinivas Group at IDRM 👇 Calcium signalling turns out to be essential for setting up the embryo’s anterior-posterior body axis. Using light-sheet microscopy, the team captured calcium activity in early mouse embryos. Read more: tinyurl.com/5999kkm8
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 27/11/2025
This week's scientific video, created by Dr Shifaan Thowfeequ from the Shankar Srinivas lab, is titled “Chasing the wave – in search of the origins of the first heartbeat.” The video captures the mechanical and chemical dynamics of an embryonic chick heart as it first forms and starts to beat.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 25/11/2025
Thanks to everyone who joined us for last week’s Get To Know Each Other event at the IDRM, and to all our fantastic speakers and poster presenters who made the afternoon such a success!
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 20/11/2025
This week’s featured scientific image, "From blueprint to beating - engineering human cardiac development in a dish," comes from Selin Tüzüner (Simões Group), whose work was selected as a finalist in the BHF Reflections of Research competition. Read more: lnkd.in/dQ4rZR9t #ScientificImaging
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 19/11/2025
✨ Monthly Featured Member ✨ Meet Mary Deadman, who recently retired after an incredible 44 years at the University, most recently as Laboratory Manager for the Holländer Group. Mary has supported countless projects and colleagues throughout her career. 🔗Read more: shorturl.at/SWhc5
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 13/11/2025
This Christmas, we’re teaming up with the Department of Paediatrics to support #Sleigh2Give and bring festive cheer to children in hospitals and families across Oxfordshire. 🎁✨ Donate brand new, unwrapped gifts by 12 Dec to help make the holidays a little brighter.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 12/11/2025
Today’s scientific image of the week, “Cellular Hummingbird”, comes from Elizabeth Figueroa-Juárez. 🧫 She’s modelling atherosclerosis in vitro using hiPSC-derived endothelial cells. ✨ The colours and shape reminded her of hummingbirds—“gods’ messengers from the afterlife,” in Mayan legend.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 06/11/2025
Today’s #ScientificImage — “Where Vessels Begin,” comes from @degrainger.bsky.social, a postdoctoral researcher in IDRM's Stone group. 💬"We are working to understand how blood and lymphatic vessels form during embryonic development and how organ-specific characteristics of these vessels arise."
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 03/11/2025
Last week's spooky creations, courtesy of IDRM's Mommersteeg Group, were carved just in time for Halloween! @tillymommersteeg.bsky.social
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 30/10/2025
Rise of the Arteries — a lightsheet image capturing the intricate vascular network of a developing mouse heart. By visualising endothelial and smooth muscle cells in 3D, researchers at IDRM reveal the beauty of coronary vessel formation. 📷 Credit: Konstantinos Miti & Polen Bareke
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 02/10/2025
New research led by @klekkos.bsky.social and @tillymommersteeg.bsky.social at the IDRM and DPAG has uncovered an essential role for oxidative metabolism in heart regeneration. Read the full paper here: www.nature.com/articles/s44... Read the overview of the study: tinyurl.com/2syythet
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 28/08/2025
Meet Antonio Garcia Guerra, a Postdoctoral Research Scientist in the Rinaldi Group, and our August featured member. Antonio's research focuses on cell-specific gene editing in neuromuscular disease. Find out more about his research: www.linkedin.com/feed/update/... @oxfordpaediatrics.bsky.social
A notebook style graphic outlining the most recent IDRM featured member, Antonio Garcia Guerra.

The following information is listed:
Postdoctoral Research Scientist
Rinaldi Group
Research Focus: Cell-specific gene editing in neuromuscular disease.

The IDRM logo is placed in the left hand corner, with a portrait of Antonio on the right.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 18/08/2025
How do you turn cutting-edge science into a business idea? We spoke with Dr Sophie Payne (IDRM, DPAG), a postdoctoral researcher, about her journey on the Oxford Venture Builder, where she pitched her enhancer-based gene therapy idea. Read the full interview: lnkd.in/dx27XkV8
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 11/08/2025
🎉Congratulations to the IDRM's Professor Sarah De Val on being awarded the title of Professor of Cardiovascular Science by the University of Oxford 🎉 #CardiovascularScience #AcademicAchievement #WomenInSTEM
Square photo showing the head and shoulders of a woman against a blurred background and outlined by a red and yellow gradient border. On the right hand sign is white text on a blue background that reads: Professor of Cardiovascular Science. Congratulations to Sarah De Val, Group Leader within the IDRM Cardiovascular Theme, who has been awarded the title of Professor of Cardiovascular Science by the University of Oxford. To the bottom left are logos for the Institute of Developmental & Regenerative Medicine, and for the University of Oxford.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 30/07/2025
🎉Huge congratulations to Dr Nancy Stathopoulou, IDRM Transition Fellow @oxfordpaediatrics.bsky.social who has been awarded the BHF Intermediate Science Research Fellowship by the @thebhf.bsky.social. Nancy’s work focuses on epigenetics in cardiac development and congenital heart disease.
Dark blue background with white text. Institute of Developmental & Regenerative Medicine logo sits in top left corner with text to the right reading: BHF Fellowship Awarded. Photo of researcher awarded is on the left highlighted within a thin frame that from red to yellow from left to right. Main text reads: Though congenital heart disease (CHD) is the most common birth defect, its causes are often unknown. This fellowship award will support Nancy's research toward understanding heart development with the ultimate aim of progressing CHD diagnosis and future therapies. Dr Nancy Stathopoulou, BHF Intermediate Basic Science Research Fellow.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 25/07/2025
👋Meet Konstantinos Lekkos, a DPhil Student in the Mommersteeg group, and our most recent featured member. Kostas' research focuses on the role of oxidative metabolism in zebrafish heart regeneration. Find out more about his research: www.linkedin.com/feed/update/... @oxforddpag.bsky.social
Square image with a background designed to look like lined note paper. Title reads as Featured Member. On the right is a faux polaroid photo of the featured member, Konstantinos Lekkos, with his name below his image. On the left are three bullet points that state 1. his job role of DPhil Student, 2. he is a member of the Mommersteeg Group, and 3. his research focus which is the role of oxidative metabolism in zebrafish heart regeneration. A dark blue band stretches across the bottom of the square to highlight a white Institute of Developmental & Regenerative Medicine logo.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 21/07/2025
🎉 Congratulations to Konstantinos Lekkos, a 2nd year DPhil student in the Mathilda Mommersteeg Group. Kostas won first prize at this year’s Oxford MRC-DTP Symposium with his talk on a novel discovery in zebrafish metabolism and heart regeneration. @oxforddpag.bsky.social
Photo shows an image of someone receiving a certificate. There is a lecturn on the right with a figure next to it holding a sheet of paper. The figure is smiling and walking towards the camera. To the left are a row of 4 people mid-clap standing in front of a screen where the words 'Awards Ceremony and Close) are partially visible. The photo is framed with two microscopy images - the left hand side is red and white on a black background, the right hand side has cells imaged in greens, blues and white on a black background. At the bottom of the frame is the logo for the Institute of Developmental & Regenerative Medicine.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 03/07/2025
It is day 3 of our #ResearchAppreciationDay2025 countdown! Dr Filipa Simões and team reveal how immune cells shape the heart from the earliest stages and guide regeneration in species like zebrafish. 🔬 Read the review: shorturl.at/kIYBf
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 02/07/2025
Next up in our countdown to #ResearchAppreciationDay2025, we are spotlighting public engagement at the IDRM! IDRM researchers took part in Pint of Science 2025, bringing research and more to local Oxford pubs. Thanks to everyone who helped make it happen! 🔗 Read more: shorturl.at/z3yUI
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 01/07/2025
Kicking off our countdown to #ResearchAppreciationDay, we’re spotlighting a study from the Stone Group at the IDRM, published in Nature Cardiovascular Research. The paper reveals that lymphatic endothelial cells can arise directly from mesenchymal progenitors, bypassing the venous endothelium.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 25/06/2025
👋Meet Claudio Cortes Rodriguez, a Postdoctoral Research Fellow in the Riley group, and our most recent featured member. Claudio's research focuses on uncovering the cause of defects in the heart wall. Find out more about Claudio's research: lnkd.in/ebKNJ-zE @oxforddpag.bsky.social
Square image with a background designed to look like lined note paper. Title reads as Featured Member. On the right is a faux polaroid photo of the featured member, Claudio Cortes Rodriguez, with his name below his image. On the left are three bullet points that state 1. his job role of Postdoctural Research Fellow, 2. he is a member of the Riley Group, and 3. his research focus which is uncovering the cause behind heart wall defects. A dark blue band stretches across the bottom of the square to highlight a white Institute of Developmental & Regenerative Medicine logo.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 19/06/2025
This #CleanAirDay, we’re highlighting the small changes and big ambitions shaping sustainability at the IDRM. Yesterday’s biodiversity walk through the Lye Valley was a good reminder of what we’re working to protect: clean air, healthy ecosystems, and time to connect with nature.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 09/06/2025
Exciting news! Dr Jacinta Kalisch-Smith, @jkalism.bsky.social, has been awarded a BHF fellowship to explore how placental blood vessels support fetal growth and development. Her research could change how we detect and prevent complications during pregnancy. 🔗 Read more: shorturl.at/OVzqq
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 23/05/2025
👋Meet Anna Catarina Ferreria, a Research Assistant in the Stathopoulou Group, and our most recent featured member. Catarina's research focuses on understanding how epigenetic factors contribute to congenital heart disease. Read more: lnkd.in/ezEdRRDm @oxfordpaediatrics.bsky.social
Square image with a background designed to look like lined note paper. Title reads as Featured Member. On the right is a faux polaroid photo of the featured member, Anna Catarina Ferreria, with her name below her image. On the left are three bullet points that state 1) her job role of Research Assistant, 2) she is a member of the Stathopoulou Group, and 3) her research focus of how epigenetic factors contribute to congenital heart disease. A dark blue band stretches across the bottom of the square to highlight a white Institute of Developmental & Regenerative Medicine logo
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 20/05/2025
🐝 Today on #WorldBeeDay, we're celebrating the buzz around IDRM! Our garden is alive with pollinators, drawn in by our blooming flowers and purpose-built bug houses. Pictured below: a ladybird, a bee, and a snail. Small but important reminders of the role of biodiversity in healthy lives.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 14/05/2025
It’s #MentalHealthAwarenessWeek, and this year’s theme is community. Feeling safe, supported and seen, especially at work, makes all the difference to our mental wellbeing. Let’s build workplaces where people feel able to speak up and get the support they need.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 12/05/2025
Researchers from the MDUK Oxford Neuromuscular Centre at IDRM ran the Oxford Town & Gown 10k in support of Muscular Dystrophy UK. Thanks to generous support and a successful bake sale, the team raised over £1,300. Congratulations to everyone who participated!
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 02/05/2025
New research from the @oliverastone.bsky.social Stone Group shows that lymphatic endothelial cells can arise directly from mesenchymal progenitors, bypassing venous endothelium. Read our conversation with the researchers to learn more: lnkd.in/dSV7W-8r 📄 Paper: lnkd.in/gz5v_ibH
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 29/04/2025
Today on #WorldImmunologyDay, we're spotlighting the immune system with this image, shared by DPhil student Andreas Tarcevski (Holländer group). It shows a cross-section of an embryo mapped for gene expression. In blue, we see the thymus - a key organ for adaptive immunity and T-cell formation.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 25/04/2025
👋Meet Ambra Speciale, a DPhil Student in the Rinaldi Group, and our most recent featured member. Her research focuses on understanding how changes in RNA editing contribute to neurological disorders. Read more lnkd.in/ezHzDZCp or hear Ambra talk bsky.app/profile/idrm... @pintofscience.uk
Square image with a background designed to look like lined note paper. Title reads as Featured Member. On the left is a faux polaroid photo of the featured member, Ambra Speciale, with their name below their headshot. On the right are three bullet points that state 1. their job role of DPhil Student, 2. they are a member of the Rinaldi Group, and 3. an overview of their research focus which is understanding how changes in RNA editing may contribute to neurological disorders. A dark blue band stretches across the bottom of the square to highlight a white Institute of Developmental & Regenerative Medicine logo.
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 23/04/2025
Come and quench your thirst for knowledge at the @pintofscience festival Oxford, 19–21 May 2025! #pint25 The Battle Against Our Own Genes: learn about treating rare genetic disorders from the IDRM's Stephan Sanders and Ambra Speciale Grab your tickets here: pintofscience.co.uk/events/oxford
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 22/04/2025
🌍 Happy Earth Day! At IDRM, we believe in world-changing science and everyday sustainability. From coffee log recycling to greener labs, small actions add up 🌱 #EarthDay2025 #GreenLabs
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 17/04/2025
In view of the upcoming holiday, we'd like to wish you Happy Easter from all of us at the IDRM! 🔬 Hope your weekend is filled with egg-citement, rest, and a few sweet experiments🧪 #Easter #IDRM #Oxford
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 15/04/2025
April is #StressAwarenessMonth — a perfect time to reflect on wellbeing in the workplace. Anna K. Shaffner, who previously gave a wellbeing seminar at the IDRM, reminds us that: “Exhaustion is a warning sign... We must allow ourselves guilt-free breaks.” #MentalHealth
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Institute of Developmental & Regenerative Medicine @idrm.ox.ac.uk · 10/04/2025
Congratulations to the IDRM team who helped raise over £3,400 for @thebhf.bsky.social in this year’s Go Red Challenge 🎉 Oxford placed second nationally, with creative fundraising events including bake sales, a wine & cheese night, and CPR training. Read more: lnkd.in/dudTWsbY
Two IDRM researchers stood behind the BHF bake sale stand
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