Simon Snoeck @simonsnoeck.bsky.social · 18/09/2026Complementary "CTNIP-SCREW-DEP/HSL3-NUT-DEPR" reads: 10.1016/j.molp.2025.10.005 (wheat) and 10.1016/j.xplc.2026.102074 184
Reposted by Simon SnoeckJack Rhodes @jackrhodes.bsky.social · 10/09/2026An embryo-derived peptide signal directs endosperm polarity in Arabidopsisscience.orgAn embryo-derived peptide signal directs endosperm polarity in ArabidopsisAngiosperm seed formation requires the coordinated development of the products of double fertilization—the embryo and the endosperm. The endosperm mediates efficient nutrient transfer from surrounding... 04722
Reposted by Simon SnoeckNew Phytologist @newphyt.bsky.social · 15/07/2026A tomato MIK2-clade receptor is involved in the perception of a Fusarium-derived elicitor Maroschek et al. nph.onlinelibrary.wiley.com/doi/10.1111/... 0118
Reposted by Simon SnoeckMauricio Contreras @mpcontreras.bsky.social · 20/05/2026Check out our latest work! AlphaFold 3 revealed a transient immune receptor complex that eluded biochemical studies for almost a decade 🤯 We describe a conserved structural logic underlying sensor–helper communication in an NLR immune receptor network 🧵👇 19843
Reposted by Simon SnoeckLin-Jie Shu @linjieshu.bsky.social · 19/05/2026A new "LORE" paper is out from Ranf lab at TUM in Germany and University of Fribourg in Switzerland: www.biorxiv.org/content/10.6... Fatty acid-sensing receptors were previously only described in Arabidopsis. Do they function the same way in other plants?biorxiv.org 295
Simon Snoeck @simonsnoeck.bsky.social · 09/12/2025Much like the Island Domain shifting its shape, our preprint has transformed too @natcomms.nature.com rdcu.be/eTOhFrdcu.beβ-sheet stabilization of the island domain underlies ligand-induced LRR-RP activation of plant immune signalingNature Communications - Using AI-based structural modeling, the authors reveal the ligand-binding and subsequent receptor complex formation mechanisms of three LRR-RP-type plant PRRs and propose a... 0115
Reposted by Simon SnoeckMichael Hothorn @structplantbio.bsky.social · 25/10/2025By the @cellsensing.bsky.social and Zipfel labs: The plant receptor kinase HSL3 senses a cyclic, disulfide-bond stabilized peptide phytocytokine. www.biorxiv.org/content/10.1... 02916
Simon Snoeck @simonsnoeck.bsky.social · 01/08/2025Is my bike a Fabaceae? San Bernardino pass, wowie! 010
Simon Snoeck @simonsnoeck.bsky.social · 09/07/2025Shedding light on the structure-function mechanisms of LRR-RPs. Our research merges #AlphaFold3, years of literature and functional validation to reveal diverse ligand-binding mechanisms and a conserved co-receptor association mechanism. www.biorxiv.org/content/10.1... 12815
Reposted by Simon SnoeckAlexey Amunts @amunts.bsky.social · 04/07/2025Speak up to prevent a major loss for the field. CASP, which helped shaping structural biology including AlphaFold is on the verge of shutting down. NIH funding has lapsed, UC Davis support ends and the core team is being let go. Painfully shortsighted.science.orgExclusive: Famed protein structure competition nears end as NIH grant money runs outAgency silent on funding renewal for contest that inspired creation of AIs that predicted how proteins would fold 06546
Reposted by Simon SnoeckbioRxiv Plant Bio @biorxiv-plants.bsky.social · 23/05/2025MIK2 clade receptor function in perception of a Fusarium-derived elicitor is conserved among different plant families www.biorxiv.org/content/10.1101/202… 065