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Hemmo Meyer Lab

@hemmo-lab.bsky.social
208 followers 132 following 24 posts

Exploring the molecular biology of #ubiquitin and #VCPp97 -mediated stress responses in cells, #proteostasis, #lysophagy, #autophagy, #DNArepair. udue.de/qmTDR

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Reposted by Hemmo Meyer Lab
Center of Medical Biotechnology @unidue-zmb.bsky.social · 15/10/2026
🎓👏 Congratulations @pinkigahlot.bsky.social of the @hemmo-lab.bsky.social on receiving the award for the Best Doctoral Thesis of the Faculty of Biology at the @unidue.bsky.social´s Dies Academicus 2026! © UDE/Eventfotograf.in
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 02/10/2026
The Meyer lab at the excellent #EMBOUbiquitin meeting near Bari, Italy, with stunning talks and posters, and ample opportunity to discuss #ubiquitin signaling. Thx to Yogesh and the whole organizing team.
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 04/09/2026
@lsajournal.org doi.org/10.26508/lsa... Paper out: Cool dTAG approach by Dani and Maike for acute perturbation of the #VCP/p97 system nailing down a function during DNA #replication. #ubiquitin. @crc1430.bsky.social @unidue-zmb.bsky.social Thanks to our collaborators, the Beli and Boos labs.
doi.org
Induced degradation of Ufd1 reveals regulation of cohesin by the VCP/p97Ufd1-Npl4 complex
The AAA ATPase VCP/p97 has emerged as a critical regulator of ubiquitin and chromatin-associated processes but progress in understanding has been hampered by the complexity of p97 functions and the va...
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 08/07/2026
Fun at this year‘s Meyer lab outing with city rallye and barbeque at beautiful Gruga park. Now back to work!
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Reposted by Hemmo Meyer Lab
CRC 1430 @crc1430.bsky.social · 03/07/2026
What a great evening at this years' company run in Essen! 🏃‍♀️🏃‍♂️🎉 Several CRC 1430 groups, including @hemmo-lab.bsky.social and @icce-unidue.bsky.social, joined the race. Great teamwork, great spirit, and lots of fun—both on and off the course! 💙 #CRC1430 #TeamScience @unidue-zmb.bsky.social
group of people from various groups of the ZMB, University of Duisburg-Essen in their sports outfit after running 5km at the company run Essen 2026. Everyone looks very happy.
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 02/07/2026
Brilliant PhD thesis defense by Daniella Munro concluding a tour de force analysis of Ufd1-Npl4 substrates using induced-degradation. Watch out for her paper…
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 01/07/2026
Our opinion article is out now on: Disentangling the response to lysosomal damage journals.biologists.com/jcs/article-... It discusses the concept of lysosome regeneration and the tools and reporters for diverse branches of the pathway. Great to work with coauthors Akiko and Shuhei.
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 26/06/2026
Concluding an exciting and productive mini-research term with Bruno Antonny and the talented Thomas Chouly (Barelli Group) at Université Côte d‘Azur. Merci pour l’hospitalité et des discussions stimulantes.
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 29/05/2026
Fantastic #autophagy meeting on the Oslo Fjord. Great talks and plenty of time and activities for discussion. Thanks to Anne, Ivan, Sharon and the other organizers for a great event.
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 13/05/2026
Cdc48/p97 nibbling on #ubiquitin! Cool single molecule analysis study by the Tans group (with us) out now. rdcu.be/firGK
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 30/04/2026
Great #ubfriends2026 meeting in Vienna. Presented our data on FAF1/2 mediated substrate loading onto VCP/p97. Fantastic talks, discussions and hospitality. Big thank you to the organizers! #ubiquitin
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Reposted by Hemmo Meyer Lab
Hellerschmied Lab @hellerschmiedlab.bsky.social · 27/03/2026
Excellent talk by our @unidue-zmb.bsky.social colleague Pinki Galhot from @hemmo-lab.bsky.social @imprs-lm.bsky.social 👏 #MK2026 @gbmev.bsky.social
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 20/03/2026
Finally celebrating Matthi‘s paper publication on p97‘s accessory adapters. Great job. doi.org/10.1126/scia...
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 06/03/2026
VCP/p97’s accessory adapters (FAF1, FAF2, UBXN7) boost unfolding and subsequent proteasomal degradation. #ubiquitin. Our paper is out now: Science Advances www.science.org/doi/10.1126/...
science.org
The accessory adapters FAF1, FAF2, and UBXN7 accelerate proteasomal degradation by increasing prior p97-mediated substrate unfolding
A group of accessory adapters positions the p97 adapter Ufd1 to boost substrate unfolding and subsequent proteasomal degradation.
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Reposted by Hemmo Meyer Lab
SFB Targeted Protein Degradation @sfb-tpd-vienna.bsky.social · 10/01/2026
Thrilled to be hosting Brenda Schulman, @aakritijain.bsky.social, @crismayorruiz.bsky.social @davidbalchin.bsky.social, @hemmo-lab.bsky.social, Ian Ganley, @kirsteinlab.bsky.social, Juliette Fedry, @elliottlab.bsky.social & @plantophagy.bsky.social - BIG THANKS for accepting the invitation 🙏
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 11/12/2025
The Meyer lab Xmas dinner once again with traditional German skittle competition. We won! 🎳
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 06/11/2025
Fantastic and productive meeting with the labs of Tamotsu Yoshimori, Shuhei Nakamura, Akiko Kuma at #Osaka University. Discussing perspectives of #microautophagy in th #lysosome regeneration after damage. Thanks so much for hosting me.
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 05/11/2025
Meeting new and old friends at the JPS conference in Kyoto, Japan. Presented our newest data on the #Lysosome Damage Response. #ATXN3 Thanks to the organizers.
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 20/10/2025
ATG9A assists lysosome membrane repair. Our preview on the Tooze lab’s paper is now online and free thru this link: authors.elsevier.com/a/1lzTz5Sx5g...
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 10/08/2025
Excellent thesis defense by Pinki Gahlot concluding brillant work on a sensor module, SPG20-ITCH that detects lipid packing defects in the limiting membrane of permeabilized #lysosomes and initiates #lysophagy.
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Reposted by Hemmo Meyer Lab
The EMBO Journal @embojournal.org · 30/07/2025
ATXN3-p97 facilitates #lysosomal restoration after damage by deubiquitinating LAMP2 and targeting it for degradation via microautophagy Hemmo Meyer and coworkers @hemmo-lab.bsky.social www.embopress.org/doi/full/10....
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 17/07/2025
Fun at the lab outing
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Reposted by Hemmo Meyer Lab
CRC 1430 @crc1430.bsky.social · 19/05/2025
A successful @crc1430.bsky.social PhD Career Day is behind us! Thank you to all participants for the lively discussions and to our six guest speakers for their valuable insights. We enjoyed a day full of career advice, inspiring talks, and great networking over dinner. #PhDCareers #JobsAfterPhD
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Reposted by Hemmo Meyer Lab
Malte Gersch @maltegersch.bsky.social · 04/05/2025
Thank you again Chuna Choudhary from @choudharylabcpr.bsky.social at CPR in Copenhagen for visiting us last week for an exiting CRC1430 @crc1430.bsky.social seminar and for discussing the systems properties of ubiquitination www.cell.com/cell/fulltex...
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 23/04/2025
We are looking for a PhD student with interest in protein biochemistry on a really cool project “Cooperation of deubiquitinating enzymes and VCP/p97 in cellular stress responses”. Build your own reactions! fully funded. apply with code 193-25. #ubiquitin
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Reposted by Hemmo Meyer Lab
CRC 1430 @crc1430.bsky.social · 17/02/2025
Concluding a productive @crc1430.bsky.social retreat with our PIs, exploring the 'Molecular Mechanisms of Cell State Transitions'. Thanks to everyone for the engaging discussions and collaborative efforts that made this retreat truly impactful! #ScienceInAction #ResearchCollaboration
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 08/04/2025
Can’t believe the fantastic Dana Branzei has joined our faculty in Essen and the #CRC1430! Esteemed expert in DNA replication and repair, Humboldt-Professor, and zabaione connaisseuse. #UDE
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 26/03/2025
Another excellent Frankfurt meeting #fcqc2025 on cellular quality control. Fantastic speaker lineup, discussions and hospitality. Thx to the organizers. #ubiquitin #autophagy fcqc.de
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 19/03/2025
Great visit in Kiel Biochemistry with Elmar Wolf, Paul Saftig, M. Damme, M. Voß. Talking exciting (lysosome) science at the beautiful Kiel Fjord.
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 11/03/2025
New VCP/p97 review article. Report on the excellent VCP meeting at CalTech last year and great overview on VCP and VCP disease. doi.org/10.1016/j.nb...
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 10/03/2025
Different ways to target substrate proteins to the VCP/p97 unfolding machine: www.frontiersin.org/journals/mol...
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Hemmo Meyer Lab @hemmo-lab.bsky.social · 10/03/2025
Our review on the lysosomal damage response is Open Access: www.annualreviews.org/content/jour...
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