iiinova — where your digital self keeps evolving

Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 16/10/2025

🥤#KidneyStone prevention — diet that protects your #kidneys 👇 🔗 doi.org/10.1136/post... #Nephrology #Urology

Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 02/08/2025

🔍Proteinuria in monoclonal gammopathy? Don’t miss the diagnostic clues! 🚰uAPR < 40%? Think tubular 🧪uAPR > 40%? Glomerular path ahead From cast nephropathy to MGRS, biopsy is 🔑 📉LC ≤10%= cast nephropathy 📊LC >10%= #LCPT 🧬 #MGRS = Biopsy it 🔗 doi.org/10.1016/j.lp... #NephSky #MGRS #MM #Medsky

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 17/06/2025

📉 Why are infections so common—and deadly—in people with chronic kidney disease? 🧠 SIDKD (Secondary Immune Deficiency of Kidney Disease) affects gut health, immune cells, metabolism & more. This visual breaks it down beautifully 👇 🔗 doi.org/10.1097/IMNA... 🆕 🧬 Nephrologists, time to zoom in!

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 16/06/2025

🚨NEW Weapons vs #MDR bugs! 💉Explore 3️⃣ hot β-lactam/β-lactamase inhibitor combos: 🦠 Cefepime/enmetazobactam 🦠 Aztreonam/avibactam 🦠 Sulbactam/durlobactam ⚖️💧Renal dose adjustments? Covered👇 🔗 doi.org/10.3390/path... 🆕 #Nephrology #MedTwitter #ICU #ID #Antibiotics #IM

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Reposted by Dr. Hardik Patel 🩺💉

Clinical Kidney Journal @ckj-era.bsky.social · 12/06/2025

Reducing CKD burden in Europe: first make the elephant apparent! doi.org/10.1093/ckj/...

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 16/06/2025

💊💓HFrEF management is evolving! Why wait months to optimize therapy? 👇Compare ESC 2021 vs McMurray/Packer 2021 strategies 💥 SGLT2i | GLP-1RA | Finerenone Game-changers in 🫀, 🫘 & 🧠 🔗 doi.org/10.3390/jcm1... #Nephrology #Cardiology #MedEd #SGLT2i #HeartFailure #CKD #IM #MedSky

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 15/06/2025

🥩🫘#HRS-AKI is more pre-renal than pre-renal AKI!🤯 Check out this mind-bending FENa table in cirrhosis-related AKI from a must-read #ICU review 🔑note: FENa is helpful—but don’t overtrust it alone! 🔗 doi.org/10.1177/0885... 🆕 #Nephrology #MedEd #AKI #Hepatology #Cirrhosis #NephSky #Hepatorenal

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 11/06/2025

🚨#SGLT2 inhibitors in cirrhosis? Where #Nephrology meets #Hepatology 🧪11/11:↓ ascites (💧less taps) 📉7/9: slowed progression (fewer decompensations) ⚠️AKI/hypotension in refractory cases—balance matters! Dual win:Natriuresis + anti-inflammatory 🔗 doi.org/10.3390/ijms...

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 05/06/2025

🎛️Hemoadsorption in septic shock? Not so fast ❌ 🚫 Immune meddling, 🎯 non‑selective action, 📉no survival edge &⚠️ potential harm 🔥 Massimo et al. editorial a must‑read for ICU & nephro teams 🔗 doi.org/10.1007/s001... 🆕 #Nephrology #ICU #Sepsis #AKI #CriticalCare #NephSky

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 04/06/2025

🚨Peripheral Artery Disease🦵 is up to 6x more common in CKD 🫘 ❤️‍🔥Vascular calcification, inflammation & CKD-MBD🦴 fuel the fire 🔥 📉Don’t miss early signs—ankle-brachial index can help! 🔗https://doi.org/10.1093/ckj/sfaf089 @ckj-era.bsky.social review #MedSky #MedEd #CKD #PAD #Nephrology #NephSky

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 01/06/2025

🦸‍♂️🦸‍♀️ Meet the Dynamic Duo in HFpEF/HFrEF! SGLT2 inhibitors🟰Robin Finerenone🟰Batman Together they battle heart failure💔 with preserved/mid-range EF! 🔗 doi.org/10.36660/abc... #NephSky #CardioRenal #HFpEF #SGLT2i #Finerenone #HeartFailure #MedSky #InternalMedicine

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 30/05/2025

🧬🔬Renal biopsy says amyloidosis… what next? This brilliant IHC-based algorithm 🔁 guides you through AL, AA, & rare amyloid types—don’t miss that dual diagnosis! 🔗 doi.org/10.1159/0005... 🆕 #RenalPath #Amyloidosis #Nephrology #MedSky #BlueSky

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 25/05/2025

🫀Heart Failure in CKD🫘 isn’t just about fluid overload — and its Rampant in CKD 🔥-it’s a perfect storm of: 🧬Neurohormones 🦠Inflammation 🧪Uremic toxins 🧱Fibrosis 💣Metabolic chaos 🔗 doi.org/10.1161/CIRC... #Nephrology #CRS #HF #HeartFailure #CKD #FOAMed #MedEd #IM #NephSky #MedSky

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 16/05/2025

🤔Ever seen IgG3 act this wild in the kidney?🫘 🔬PGNMID = mysterious monoclonal Ig with renal-limited fury 🧩Pathophys still unclear but beautifully illustrated here👇 📖Bridoux et al @ndt-era.bsky.social 🔗 doi.org/10.1093/ndt/... #Nephrology #MGRS #PGNMID #MedTwitter #RenalPath #NephTwitter

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 27/04/2025

🚀Adrenal Incidentalomas Demystified 🥴Stumbled upon an adrenal mass ? Here’s your roadmap🚏 👉🏻Workup algorithm—from benign to suspicious 🦀what’s next? ⭐️A must-know for #Nephrology #Endocrinology #Urology 👩‍⚕️ 🔗 doi.org/10.1097/JU.0... #Incidentaloma #FOAMed #MedSky #NephSky

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 26/04/2025

💉Immune checkpoint inhibitors: 🦸‍♂️heroes in cancer🦀, 🦹‍♂️villains for kidneys 🫘? #ICI-AKI can hit both Glomeruli (C3GN, MCD, vasculitis) & Tubulointerstitium (ATIN, ATN, tubulitis) 📖 doi.org/10.34067/KID... 🆕 @asnpublications.bsky.social K360 #Onconephrology #Nephrology #AKI #NephSky #NephPearls

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 26/04/2025

🧰New tools for early ICI-AKI detection! 💧Urine, 🩸 serum, and 📸 imaging markers are changing the game. Protect kidneys 🫘 , save lives!🌱 🔗 doi.org/10.34067/KID... @asnpublications.bsky.social K360 @sabinekaram.bsky.social et al #Nephrology #OncoNephrology #AKI #NephSky #MedSky #NephPearls

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 30/03/2025

🦀🦴Treatment of Cancer-Associated Hypercalcemia ➡️Start with IV fluids ➡️Then hit osteoclasts with #Bisphosphonates or #Denosumab But remember, real control = treating the malignancy 🔗 www.nejm.org/doi/full/10.... #Hypercalcemia #Malignancy #OncoNephrology #Nephrology #IM #Oncology #MedSky #NephSky

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 30/03/2025

The CKD-Gut-Immune Axis: A Vicious Cycle 🫘 Uremic toxins → Gut dysbiosis → Inflammation → Immune dysregulation → CKD progression. Can probiotics break the cycle? 📖 dx.doi.org/10.5527/wjn.... 2025 🆕 #Probiotics #Nephrology #CKD #GutHealth #Uremia #MedSky #NephSky

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 22/03/2025

#Leptospirosis & the #Kidney: A Deadly Duo🦠🫘 Lepto= non-oliguric #AKI→ ATN→ #CKD by blocking Na-K ATPase & inducing vasopressin resistance! Persistent inflammation= fibrosis & kidney failure. 🔗 doi.org/10.1007/s150... 🆕 2025 #Nephrology #InfectiousDiseases #InternalMedicine #MedSky #NephSky

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 15/03/2025

💡Pregnancy after transplant? 🤰🫘🫁🫀 What you need to know! 🔹Pre-pregnancy guidance 🔹Organ-specific outcomes 🔹Risks & expert recommendations 📖 doi.org/10.1097/TP.0... 🆕 @gonikatz.bsky.social @ttsorg.bsky.social (2025) #TransplantNephrology #Pregnancy #Nephrology #MedTwitter #Transplantation

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 15/03/2025

⚠️Sterile Peritonitis in PD: Think Beyond Infection 🦠 🔍Not always infection! A broad differential—drugs, malignancy, retrograde menstruation & more! 🏥💡 Freitas et al 🔗https://doi.org/10.1177/089686080502500207 #Nephrology #PeritonealDialysis #PD #MedEd #FOAMed #Dialysis #NephSky #MedSky

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 11/03/2025

🚨Endocrine Hypertension: More Than Just BP🚨 From resistant HTN to adrenal tumors—when should you suspect & how do you approach? 📊🔎 📖Borozan et al., Current Hypertension Reports (2025) 🔗 doi.org/10.1007/s119... 🆕 #Hypertension #Endocrinology #Nephrology #NephSky #MedSky

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 09/03/2025

🚰🔄Vesicoureteral Reflux (VUR): A Silent Threat to Kidneys🫘 From mild reflux to severe tortuosity—grading VUR is key📊 Know when & how to investigate🔍 @diseaseprimers.bsky.social 📖 doi.org/10.1038/s415... (2024-Primer) #Nephrology #PedsNephro #VUR #UTI #MedEd #FOAMed #NephSky #MedSky

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Reposted by Dr. Hardik Patel 🩺💉

Jasmine Sethi @jasminenephro.bsky.social · 22/02/2025

💊🫘Drugs to prevent CKD Progression doi.org/10.1093/ndt/... @hjanders.bsky.social

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Reposted by Dr. Hardik Patel 🩺💉

Jasmine Sethi @jasminenephro.bsky.social · 07/03/2025

🫘Renal Amyloidosis academic.oup.com/ndt/article-... @hjanders.bsky.social

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Reposted by Dr. Hardik Patel 🩺💉

Jasmine Sethi @jasminenephro.bsky.social · 07/03/2025

🫘Non invasive biomarkers of Rejection pubmed.ncbi.nlm.nih.gov/39419272/ @ajkd.bsky.social

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 06/03/2025

Antiphospholipid Syndrome (APS): The Silent Thrombophilia From molecular pathogenesis to devastating thrombotic complications—#APS is a ticking time bomb! ⏳🧬 📖 APS review: doi.org/10.3390/jcm1... (2025) #Nephrology #Thrombosis #Lupus #MedTwitter #Rheumatology #Autoimmune

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 05/03/2025

Struggling with hyperphosphatemia in dialysis patients? 🦴🫘 Meet #Tenapanor! It inhibits paracellular phosphate absorption by modulating NHE3 & tight junctions. A novel way to tackle phosphorus! 🔬💊 #Nephrology #Hyperphosphatemia #Dialysis #HD 📖https://doi.org/10.1053/j.jrn.2024.07.003

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 03/03/2025

🚨ECMO & AKI: A Deadly Combo🚨 Non-pulsatile flow & venous congestion—ECMO risks renal hypoperfusion, leading to AKI🫀🫘 Can we prevent it? Dive into this review👇 📖AKI in ECMO: Research Progress 🔗https://doi.org/10.1007/s10157-024-02559-7 #Nephrology #ECMO #AKI #CriticalCare #Cardiology #ICU

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 02/03/2025

⚒️Gut-Kidney Crosstalk in AKI 🫘 ‼️Dysbiosis, leaky gut & TMAO link microbiota to kidney injury🦠 ➡️Can Probiotics & FMT 🧫🧪be game changer? 🔗 doi.org/10.1093/ndt/... 🆕 by Shishir Kumar Patel et al. @ndt-era.bsky.social @hjanders.bsky.social #Nephrology #MedSky #AKI

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 01/03/2025

🧐How does your kidney sense oxygen? The #HIF pathway holds the key! 🏥🔬 From hypoxia to gene expression, this intricate system regulates metabolism, angiogenesis & survival 🔗 doi.org/10.1093/ndt/... 🆕 @hjanders.bsky.social @NDT #Nephrology #Hypoxia #MedSky #Physiology

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 01/03/2025

⚡️New drugs, new electrolyte twists⚡️ ICIs, SGLT2i, ARNI, ns-MRA,GLP-1RA—game changers in nephrology, but are we watching their electrolyte impact closely? This table breaks it down! 👀 Surprised 📖 doi.org/10.1007/s101... #Nephrology #OncoNephrology #MedSky #Electrolytes

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 28/02/2025

🧂🔄 Hyponatremia & Urinary Dilution – The Balancing Act Three key steps for dilute urine formation: 💧 Adequate flow to distal nephron 🌀 Solute reabsorption in TAL 🚫 No AVP action in collecting duct Clinical Pearls in this review: 🔗 doi.org/10.1007/s101... #Nephrology #Hyponatremia #MedEd #FOAMed

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 28/02/2025

🚨 Hyponatremia? Don’t just give hypertonic saline—think🧂 1️⃣ Assess urgency 🚑 2️⃣ Rule out hypertonic/isotonic causes 🩸 3️⃣ Check urine osmolality & sodium to find the culprit Master the approach with this must-read review: 🔗 doi.org/10.1007/s101... #Nephrology #Hyponatremia #NephPearl

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 26/02/2025

🚀 Unveil the magic of ARNI (e.g., Valsartan-Sacubitril) in heart failure! 💥 Boosts natriuresis, vasodilation, and more for heart-kidney harmony! 🫀🫘 #ARNI #Nephrology #HeartFailure #CardioRenal

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 25/02/2025

Obesity isn’t just extra weight ⚖️—it’s a multi-organ threat! ❤️ 🧠 🫘 🩸 From heart disease to kidney dysfunction, the risks are real But GLP-1 RAs 💉offer hope by targeting appetite & metabolism 📖 doi.org/10.1016/j.am... (2025) #Nephrology #Obesity #GLP1

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 24/02/2025

💡 Who should get #Tolvaptan in #ADPKD? A stepwise approach to identifying rapid disease progression 📈 ✔️ eGFR decline >3 ml/min/yr? Treat! ✔️ Imaging/genetic risk? Assess! 📊 @BMCNephrology 🔗 doi.org/10.1186/s128... #Nephrology #Kidney #NephBlueSky

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Reposted by Dr. Hardik Patel 🩺💉

Joel Topf @kidneyboy.bsky.social · 23/02/2025

These are awesome and are finding there way into my MS2 lectures for next year

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 24/02/2025

🚨 Tolvaptan = Game changer for #ADPKD, but beware of side effects! 🚨 🧂 Polyuria, thirst, hypernatremia 🩸 Liver toxicity 🤢 GI issues 💡 Risk-benefit discussion is key! 📊 #Tolvaptan S/E frequency @BMCNephrology 🔗 doi.org/10.1186/s128... #Nephrology

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 23/02/2025

MRA: A powerhouse for the heart & kidneys! 🛡️❤️🫘🩺 From #HeartFailure to #CKD & #Dialysis—MRAs bridge the gap between CV & renal benefits! Game-changer for #HFrEF, post-MI & #ESRD patients. 📖 doi.org/10.1097/FJC.... (2025) #Nephrology #Cardiology #MRAs #NephPearl

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 22/02/2025

🔍 Unraveling CKDu 🫘 mystery! 🌡️☀️Heat stress, nephrotoxins☣️ & rural hardship—silent drivers of CKDu!🚜 🚦Pathophysiology of heat stress, and clinical clues in this eye-opening review💡 doi.org/10.1111/tmi.13… #Nephrology #CKDu #PublicHealth #NephSky #NephPearl #HeatStress

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 21/02/2025

🌟Beyond Testing—IgAN Trials Unveiled!-Must Read🌟 From #Sparsentan to #Iptacopan, innovative non-immunomodulatory & immunomodulatory therapies are transforming IgAN care!🎯 🔬 Excellent Trial insights by @Melgreux 📖 via @KidneyKolumns Jan25 #Nephrology #IgAN #ClinicalTrials

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Dr. Hardik Patel 🩺💉 @hardik4u24.bsky.social · 21/02/2025

🧬 This #AKI diagnostic flowchart is a game-changer—uncover glomerulonephritis🫘, rhabdomyolysis, & more with targeted tests. Must-know for every nephrologist! 🔍 📖 doi.org/10.1186/s130... #Nephrology #MedEd #CriticalCare

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