Organoids and engineered tissues have emerged as powerful models of human biology, yet their development and function are often characterized through endpoint measurements that provide only static snapshots of dynamic biological processes. Recent advances in stretchable mesh electronics, developmental biointegration, and organoid engineering have enabled the creation of cyborg tissues with embedded sensing, stimulation, and computational capabilities. This review highlights recent progress in developmental bioelectronic integration, multifunctional tissue mapping, biological state reconstruction, and artificial intelligence (AI)-enabled cyborg systems. We discuss how embedded bioelectronics can be combined with molecular and spatial profiling technologies to characterize tissue function, developmental trajectories, and biological states. These advances establish cyborg tissues as biologically integrated platforms for regenerative medicine, disease modeling, drug discovery, and adaptive biotechnology.

A living map of what Bluesky is talking about: the past week's conversations, grouped into topics and regions and rebuilt every six hours.

Your DNA is full of stories

The amoeba Incendiamoeba cascadensis demonstrates that eukaryotic life can withstand temperatures beyond what was thought possible and sheds light on molecular strategies for survival in extreme heat.

Nature Human Behaviour - Embryo screening and the new reproductive divide

Ancient viral warfare could be at the root of modern class 1 CRISPR bacterial defense systems

Biologists argue that gentoo penguins should be divided into four separate species, including a newly recognized “cryptic” species. The habitats of three of them are imperiled by climate change.

Comb jellies are helping answer fundamental questions in biology, from how the earliest nervous systems evolved to how bioluminescence works.

Fewer people are reading for pleasure, but getting lost in a good book has repeatedly been linked to substantial cognitive benefits

Scientists are probing whether language models trained on historical data can reproduce creative breakthroughs.

Large-language models (LLMs) are rapidly becoming part of human culture, reshaping how information is produced, transmitted, and used. Here we propose that their diffusion can be understood through a ...

A novel Asgard archaeon, Nerearchaeum marumarumayae, is present in microbial mats in Shark Bay, Australia. Combining genomic and structural analyses, together with high-resolution electron cryotomogra...

Sarah Demers, chair of the physics department at Yale University, sees the potential for large language models to both help and harm her field.

Lightning, leaves, and anchors

Snake embryos coil, but how and why they corkscrew remains unexplored. Weber et al. find that the embryos wind up clockwise via buckling of the rapidly elongating axial body against the slow-growing, ...

Admixture between modern humans and extinct hominins has shaped the genomes of present-day individuals, but reconstructing this history has been constrained by the scarcity of archaic samples and unad...

Geochemical clues hint that worm-like creatures in the Ediacaran period benefited from symbiosis with bacteria.

Superlative things were done in the past century by marshalling thousands of people in the service of a vision of the future

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Animal chromosome homology can persist over hundreds of millions of years, despite fusions and translocations. The frequency, pace, and impact of these changes remain unclear. We develop a multiscale ...

Alt: Scene from The Jungle Book in which Bagheera tries to grab Mowgli only to have a door slammed in his face by a dressed-up Baloo.

A groundbreaking study hints at a hazy boundary between “life” and “non-life,” as well as two distinct origins of biology on Earth

Bee brain, bee bright, and the point(lessness) of (human) intelligence

Bee brain, bee bright, and the point(lessness) of (human) intelligence

The sex reversal technique could be used to help rescue endangered species, say the researchers behind the work.