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Niklaus Grunwald

@grunwald.bsky.social
894 followers 698 following 3.4K posts

Genomic epidemiology, population genomics, plant pathology, pathogen emergence, #Oomycetes, #Phytophthora, #SuddenOakDeath. Opinions are my own. 🧬🦠🧪🖥️

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Niklaus Grunwald @grunwald.bsky.social · 13/05/2026
Heat-tree: Cross-Platform Software for Interactive and Embeddable Phylogenetic Tree Visualization and Editing doi.org/10.1094/PHYT...
doi.org
Heat-tree: Cross-Platform Software for Interactive and Embeddable Phylogenetic Tree Visualization and Editing | PhytoFrontiers™
Phylogenetic trees are the primary framework for conveying evolutionary relationships. While many tools exist for visualizing phylogenetic trees, most are limited to static graphics, require coding expertise, or are developed for a specific website and not easily reusable or extensible. To address these limitations, we developed heat-tree, a collection of software packages in JavaScript, R, and Python for interactive visualization, manipulation, and editing of phylogenetic trees and their associated metadata. Heat-tree allows for the creation of customizable, web-compatible tree visualizations that can be easily embedded in R Markdown, Jupyter Notebooks, and Quarto documents, as well as directly in HTML/JavaScript applications and websites. The package supports radial and rectangular tree layouts, automated translation of metadata values into visual encodings on the tree, interactive tree editing, and export capabilities for publication-quality figures. All visualization parameters are definable programmatically or interactively using the comprehensive graphical user interface included with each visualization. Heat-tree was designed to be a user-friendly software package for interactive tree viewing, manipulation, editing, and self-contained, embeddable visualization across software environments.
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Richard Sever @richardsever.bsky.social · 19/11/2025
Understanding bioRxiv/medRxiv DOIs. How openRxiv assigns them, a changing prefix, and the embedded priority date in citations openrxiv.org/dois-for-pre...
openrxiv.org
Understanding DOIs for preprints: how openRxiv assigns and manages persistent identifiers - openRxiv
Digital object identifiers (DOIs) are a class of persistent identifier (PID) assigned to an object to ensure that it can always be uniquely identified and, ideally, accessed reliably. Each DOI is a un...
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Niklaus Grunwald @grunwald.bsky.social · 19/11/2025
Great satire: www.nature.com/articles/d41...
nature.com
Introducing the j-metric: a true measure of what matters in academia
Science has become obsessed with publishing numbers. With this new satirical proposal, have we reached peak metric?
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Niklaus Grunwald @grunwald.bsky.social · 03/11/2025
Our PathogenSurveillance pipeline is out in bioRxiv. PathogenSurveillance is an open-source and automated Nextflow pipeline for population genomic analyses of WGS data. It is flexible, using both short and long read data, mixed samples of prokaryotes and eukaryotes. www.biorxiv.org/content/10.1...
biorxiv.org
PathogenSurveillance: an automated pipeline for population genomic analyses and pathogen identification
Whole genome sequencing (WGS) offers a comprehensive, organism-agnostic method that effectively meets the need for efficient, reliable, and standardized responses to emerging threats from pathogens an...
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Niklaus Grunwald @grunwald.bsky.social · 23/10/2025
A one-of-a-kind repeated natural experiment. Population Genomic Analysis of Two Independent Clonal Invasions of the Sudden Oak Death Pathogen into One Forest | Phytopathology® apsjournals.apsnet.org/doi/10.1094/...
apsjournals.apsnet.org
Population Genomic Analysis of Two Independent Clonal Invasions of the Sudden Oak Death Pathogen into One Forest | Phytopathology®
Upon introduction, clonal pathogen populations are expected to go through a genetic bottleneck followed by gradual clonal divergence. Two distinct and purely clonal lineages of the sudden oak death pa...
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Niklaus Grunwald @grunwald.bsky.social · 22/10/2025
If you admix barcodes in your Illumina library, use Demulticoder: An R Package for the Simultaneous Analysis of Multiplexed Metabarcodes | Phytopathology® apsjournals.apsnet.org/doi/10.1094/...
apsjournals.apsnet.org
Demulticoder: An R Package for the Simultaneous Analysis of Multiplexed Metabarcodes | Phytopathology®
Metabarcoding is a widely used approach relying on short DNA sequences to identify organisms present in a community. Although established workflows exist for analysis of single metabarcodes, these are...
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Niklaus Grunwald @grunwald.bsky.social · 21/10/2025
Novel insights into CAZY pathogenicity factor AA7 involved in plant immune-modulatory function: doi.org/10.1038/s414...
doi.org
Oomycetes manipulate plant innate immunity through galacturonide oxidases - Nature Communications
The oomycete Phytophthora infestans is a damaging crop pathogen. Here, the authors show that a group of P. infestans secreted enzymes play roles in penetration and colonization of host plants by oxidi...
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American Phytopathological Society (APS) @plantdisease.bsky.social · 16/10/2025
On this #WorldFoodDay, we celebrate the efforts of those who nourish our communities, protect our planet, and shape a better future through better food for all. Explore resources to learn more about food security and sustainability. #FAO80 bit.ly/4nqN3x7
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Niklaus Grunwald @grunwald.bsky.social · 07/10/2025
Working on invasive organisms? Weeds, pests, pathogens or animals? Consider submitting your work to www.cabidigitallibrary.org/journal/ab/s...
cabidigitallibrary.org
CABI Agriculture and Bioscience - Special Issues: Invasive Pathogens| CABI Digital Library
An open access journal publishing multi-, inter- and transdisciplinary research that addresses global challenges in agriculture and the environment. The editors welcome research from a wide range of f...
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Niklaus Grunwald @grunwald.bsky.social · 03/10/2025
Australia has one of the best and most rigorous approaches and we can all learn from your experience. I like the thought of strategies to build and maintain social license and trustworthiness before, and during any outbreak and the period of response.
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Niklaus Grunwald @grunwald.bsky.social · 03/10/2025
I am leading an effort to identify gaps in plant biosecurity? Please let me know your thoughts on what is currently missing?
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Cameron Thrash @jcamthrash.bsky.social · 02/10/2025
Microbial phenazines: biosynthesis, structural diversity, evolution, regulation, and biological significance journals.asm.org/doi/abs/10.1... #jcampubs
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Science Magazine @science.org · 01/10/2025
Jane Goodall has died at the age of 91. In 2020, Goodall spoke with Science Editor-in-Chief H. Holden Thorp for a #ScienceEditorial reflecting on the 60th anniversary of her arrival in Gombe to study wild chimpanzees. Read more: scim.ag/472Chb8
"… Goodall’s … is a story of genuine scientific curiosity, determination, and respect for
nature and humanity …" H. Holden Thorp, Editor-in-chief, Science journals
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Richard Sever @richardsever.bsky.social · 24/09/2025
HHMI adopts Plan U journals.plos.org/plosbiology/...
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Niklaus Grunwald @grunwald.bsky.social · 18/09/2025
@jpodwyer.bsky.social led this elegant and novel approach using genomic demography to make ecological predictions. I am excited to have played a small part in this elegant work: Genomic demography predicts community dynamics in a temperate montane forest | Science www.science.org/doi/10.1126/...
science.org
Genomic demography predicts community dynamics in a temperate montane forest
Species population sizes fluctuate over time, and these temporal dynamics play a key role in governing the maintenance of biodiversity. Although modeling approaches have been developed to characterize...
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Niklaus Grunwald @grunwald.bsky.social · 18/09/2025
Genomic demography predicts community dynamics in a temperate montane forest | Science www.science.org/doi/10.1126/...
science.org
Genomic demography predicts community dynamics in a temperate montane forest
Species population sizes fluctuate over time, and these temporal dynamics play a key role in governing the maintenance of biodiversity. Although modeling approaches have been developed to characterize...
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Niklaus Grunwald @grunwald.bsky.social · 05/09/2025
Just brilliant. Also works for bureaucrats, not just deans www.mcsweeneys.net/articles/fac...
mcsweeneys.net
Faculty, Rejoice: Gmail Can Now Translate “Deanspeak”
We are thrilled to announce that Google Translate has recently added “Deanspeak” to its suite of language-detection tools. In addition to offering ...
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Niklaus Grunwald @grunwald.bsky.social · 29/08/2025
www.nature.com/articles/d41...
nature.com
Research posts on Bluesky are more original — and get better engagement
Bluesky posts about science garner more likes and reposts than similar ones on X.
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Niklaus Grunwald @grunwald.bsky.social · 24/08/2025
Scientists are removing words like “diverse” and “disparities” from hundreds of federal grant renewals to avoid getting flagged in the Trump administration’s focus on eliminating diversity
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The Oregonian @oregonian.com · 16/08/2025
Out-of-pocket ACA premium payments will likely increase about 75% on average next year due to Congressional actions.
oregonlive.com
Liz Weston: Married couple faces likely 300% increase in their medical insurance premiums
Out-of-pocket ACA premium payments will likely increase about 75% on average next year due to Congressional actions.
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Anne Lutz Fernandez @lutzfernandez.bsky.social · 21/07/2025
ICYMI-- I did. A study of software developers found it took them 19% more time to do their work when they used AI tools. At the same time, they *perceived* they had saved time. They thought they would work faster and so they falsely "believed AI had sped them up by 20%."
metr.org
Measuring the Impact of Early-2025 AI on Experienced Open-Source Developer Productivity
We conduct a randomized controlled trial to understand how early-2025 AI tools affect the productivity of experienced open-source developers working on their own repositories. Surprisingly, we find th...
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Nature Microbiology @natmicrobiol.nature.com · 08/08/2025
#NatMicroPicks Hidden microbial world in trees🌳 Living wood hosts trillions of bacteria making trees a complex ecosystems with major roles in forest health and function. #PlantMicro #MicroSky www.nature.com/articles/s41...
nature.com
A diverse and distinct microbiome inside living trees - Nature
Microbiome analyses of living trees show that a single tree can host approximately one trillion bacteria, with microbial communities distinctly partitioned between heartwood and sapwood and with minim...
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PlantEvolution 🌱🌾 @plantevolution.bsky.social · 10/08/2025
Wonderful (and humble) essay on mentorship by Brandon Gaut, on occasion of Brandon receiving the inaugural Mentorship Award of @genetics-gsa.bsky.social. I hope this will be widely read! academic.oup.com/genetics/art...
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Niklaus Grunwald @grunwald.bsky.social · 05/08/2025
www.wsj.com/science/scie...
wsj.com
Scientific Journals Can’t Keep Up With Flood of Fake Papers
The source of the trouble is “paper mills,” businesses or individuals that charge fees to publish fake studies in legitimate journals.
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Niklaus Grunwald @grunwald.bsky.social · 04/08/2025
Ben Hoyt conducting a population genomic analysis of the ‘bulldozer’ Phytophthora cinnamomi #planhealth2025
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AmirAli Toghani @amiralito.bsky.social · 09/05/2025
Happy to share that our Helixer deeplearning-based annotation of 230 superasterid genomes is now online on @datadryad.bsky.social 💻🌱 doi.org/10.5061/drya... Check out how we used 69 of them to study the molecular evolution of a plant immune receptor network here! 👇
doi.org
Dryad | Data -- Deep-learning-based annotation of 230 superasterid genomes reveals a harmonized dataset of 91,366 NLRs
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Niklaus Grunwald @grunwald.bsky.social · 28/07/2025
www.science.org/content/arti...
science.org
USDA reorganization will cut agricultural and forest research
One of the agency’s largest and most storied research facilities will be closed along with most forest research stations
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David Cooke @llewelyn68.bsky.social · 23/07/2025
Formatted pdf now available. Over 100 authors from across the world agree to protecting the genus Phytophthora against burdensome and unnecessary taxonomic change apsjournals.apsnet.org/doi/10.1094/...
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Holly Bik @hollybik.bsky.social · 18/07/2025
UC Irvine keeps expanding its focus on microbial ecology and microbiome science - an exciting place to work for any early-career people on the hunt for a job!
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Morgan Carter @morgancarterphd.bsky.social · 17/07/2025
Preprint on antimicrobial prediction pipeline: www.biorxiv.org/content/10.1...
biorxiv.org
AMAPEC: accurate antimicrobial activity prediction for fungal effector proteins
Fungi typically occur in environments where numerous and diverse other microbes occur as well, often resulting in fierce competition for nutrients and habitat. To support fungal fitness in these envir...
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Niklaus Grunwald @grunwald.bsky.social · 16/07/2025
In memory of our dear colleague, John McDowell, who left us all too early. RIP. doi.org/10.1094/MPMI...
doi.org
John Matthew McDowell: A Visionary Leader in Molecular Oomycete-Plant Interactions and a Wonderful Mentor and Friend to Many | Molecular Plant-Microbe Interactions®
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Shahid Mukhtar @smukhtarlab.bsky.social · 16/07/2025
We lost a Grangle family member, a friend, and a visionary scientist. “A note from Jeff Dangl: John McDowell was a former MPMI Editor and great membr of our community and that it is apt that his memory be recognized at the current #2025ISMPMI nam12.safelinks.protection.outlook.com?url=https%3A...
nam12.safelinks.protection.outlook.com
John Matthew McDowell: A Visionary Leader in Molecular Oomycete-Plant Interactions and a Wonderful Mentor and Friend to Many | Molecular Plant-Microbe Interactions®
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Niklaus Grunwald @grunwald.bsky.social · 15/07/2025
www.nature.com/articles/d41...
nature.com
Scientists hide messages in papers to game AI peer review
Some studies containing instructions in white text or small font — visible only to machines — will be withdrawn from preprint servers.
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Niklaus Grunwald @grunwald.bsky.social · 12/07/2025
Quoting WSJ: A March 2025 survey by the journal Nature of more than 1,600 scientists in the U.S. found that three-quarters have considered leaving the country. Respondents specifically cited the Trump administration’s hostility to scientific research and those who practice it.
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Niklaus Grunwald @grunwald.bsky.social · 12/07/2025
www.wsj.com/politics/pol...
wsj.com
America’s Brain Drain Could Become the World’s Brain Gain
Research-funding cuts and immigration changes threaten some of America’s economic advantages.
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Niklaus Grunwald @grunwald.bsky.social · 11/07/2025
... and the famous Meselson-Stahl PNAS paper: www.pnas.org/doi/abs/10.1...
pnas.org
The replication of DNA in Escherichia coli* | PNAS
The replication of DNA in Escherichia coli*
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Niklaus Grunwald @grunwald.bsky.social · 11/07/2025
The most beautiful experiment in biology ... www.nytimes.com/2025/07/07/s...
nytimes.com
Franklin W. Stahl, 95, Dies; Helped Create a ‘Beautiful’ DNA Experiment
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The Oregonian @oregonian.com · 11/07/2025
Oregon has no reports so far of people contracting the virus. But it's still wise to cover up and prevent bites, health officials say.
oregonlive.com
West Nile virus detected in Oregon mosquitoes
Oregon has no reports so far of people contracting the virus. But it's still wise to cover up and prevent bites, health officials say.
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Juan A. Navas-Cortes (personal) @janavascortes.bsky.social · 10/07/2025
Nuevos datos sobre la virulencia, temperatura y patosistemas de Xylella fastidiosa en olivo y arándano Fuente: www.oleorevista.com/texto-diario... @blancaracol.bsky.social @iascsic.bsky.social
oleorevista.com
Nuevos datos sobre la virulencia, temperatura y patosistemas de Xylella fastidiosa en olivo y arándano
Estas diferencias se asociaron a mutaciones y secuencias únicas detectadas mediante análisis genómico y ensayos en microfluidos.Respuesta diferencial en olivo y arándanoLas inoculaciones en ...
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Susan Schlimpert @s-lab.bsky.social · 10/07/2025
New Independent Fellowship position in Microbiology to launch your lab in our department @johninnescentre.bsky.social (UK). We are conducting a broad search in the area of plant-associated microbial interactions. Message me if you have any questions. Apply here: www.jic.ac.uk/vacancies/in...
jic.ac.uk
Independent Fellowship in Plant-Associated Microbial Interactions | John Innes Centre
An exciting opportunity for an Independent Fellowship in Plant-Associated Microbial Interactions has arisen at the John Innes Centre. To read the full job description for this role…
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Zack Labe @zacklabe.com · 08/07/2025
I can't stress enough how close U.S. science is to the cliff. "Numbers released in May by the National Science Foundation (NSF) indicate that if Congress approves the cuts to the agency proposed by the White House, the number of early-career researchers it supports could fall by 78%" (@science.org)
science.org
‘It’s a nightmare.’ U.S. funding cuts threaten academic science jobs at all levels
“There is a lot of pressure to essentially leave the country or not pursue research,” one Ph.D. student says
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chasingmicrobes @chasingmicrobes.bsky.social · 06/07/2025
We are now in the time of year where should be seeing dramatic increases in NIH notices of awards (NOAs) Graphs: New SBIR and RO1 award notifications in 2025 compared to prior years. Data from NIH RePORTER, code to reproduce here: gist.github.com/chasemc/fda6...
Graph showing historical NOAs for new SBIR awards by month with sharp increases beginning in June and ending in September, when new NOAs go to 0. Corresponding with the end of the fiscal year.
The NOAs for 2025 are shown separately and have been below 1 and 2 standard deviations from the mean all year, with no sharp increase yet.Graph showing historical NOAs for new year-1 R01 grants by month with sharp increases beginning in June and ending in September, when new NOAs go to 0. Corresponding with the end of the fiscal year.
The NOAs for 2025 are shown separately and have been below 1 and 2 standard deviations from the mean all year, with no sharp increase yet.
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Alexandra Weisberg @weisbergaj.bsky.social · 09/07/2025
BPP @ Oregon State is hiring an open rank tenure track position in any area of plant systematics, ecology, and evolution and to direct our herbarium. Come join us in a great department and beautiful Oregon! bpp.oregonstate.edu/bpp/about/op...
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Dan Kliebenstein @spicybotrytis.bsky.social · 09/07/2025
No news since December except for an email two weeks ago with the reviews saying they were still evaluating administration priorities. No new funding calls released either. Way more clamped down then NIH or NSF.
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Stephen Turner @stephenturner.us · 09/07/2025
BEAST X for Bayesian phylogenetic, phylogeographic and phylodynamic inference www.nature.com/articles/s41... 🧬🖥️🧪 github.com/beast-dev/be...
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Carl Zimmer @carlzimmer.com · 09/07/2025
Measles Cases Hit Record High, 25 Years After U.S. Eliminated the Disease. Gift link: nyti.ms/4kxfY0V
nyti.ms
Measles Cases Hit Record High Since U.S. Eliminated Disease
Experts worry that if vaccination rates do not improve, deadly outbreaks will become the new normal.
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Posit @posit.co · 09/07/2025
We are thrilled to announce gt-extras, a collection of helper functions for creating beautiful tables with the great-tables package in #Python! Add plots, icons, color gradients, and more to your tables. Learn more here: posit-dev.github.io/gt-extras/ar...
A graphic with a purple and white hexagon containing the letters "GT" and the text "gt-extras" in the bottom left. On the right, a table titled "Car Performance Review" lists various car models, manufacturers, years, horsepower, torque, MPG_C, MPG_H, and efficiency ratings. The table includes models like California, GTC4Lusso, FF, F12Berlinetta, LaFerrari, NSX, GT-R, Aventador, Huracan, and Gallardo, with manufacturers Ferrari, Acura, Nissan, and Lamborghini. The top right corner features a "posit" logo.
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Niklaus Grunwald @grunwald.bsky.social · 09/07/2025
extension.oregonstate.edu/news/oregon-...
extension.oregonstate.edu
Oregon State’s plant detectives protect natural landscapes, one case at a time
The OSU Plant Clinic offers expert analysis, guidance for disease control, and hands-on learning support as part of Oregon State’s larger Extension and research mission.
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Jonathan Pritchard @jkpritch.bsky.social · 07/07/2025
Staff scientist position (computational): I am looking for a computational scientist to join my genomics lab at Stanford. They should have an outstanding skillset in ML/statistical methods for genomic applications, postdoc experience and a strong publication record. #sciencejobs
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Gitta Coaker @gittacoaker.bsky.social · 09/07/2025
The situation is such a stupid self sabotage. Although I *think* my lab will survive the chaos, most of my trainees - who are truly excellent- plan to look for their next positions outside of the US. This shift was rare before the last year. www.science.org/content/arti...
science.org
‘It’s a nightmare.’ U.S. funding cuts threaten academic science jobs at all levels
“There is a lot of pressure to essentially leave the country or not pursue research,” one Ph.D. student says
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