iiinova — where your digital self keeps evolving

Gregor lab @gregorlab.bsky.social · 21/07/2026

“Illuminating the Architecture of Thought” by our Postdoc @GemperleJakub (@imgprague) has won the Prague @EuroBioImaging Node Picture of the Month. Congrats jakub! @imgprague imcf.natur.cuni.cz/IMCF/picture-o… #neuron #Live-cell imaging of a mature primary neuron through microinjected GFP

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Gregor lab @gregorlab.bsky.social · 21/05/2026

“The Aquarelle of Motion” by our PhD student Vera Getmanchuk-Zaporoshchenko (@imgprague) has won the Prague @EuroBioImaging Node Picture of the Month. Congrats Vera! imcf.natur.cuni.cz/IMCF/picture...

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Gregor lab @gregorlab.bsky.social · 05/05/2026

@Gregor_lab #labretreat 2026: two days of exploring new angles of our projects, hiking, enjoying great food, and sharing lots of laughter in the beautiful scenery of Český ráj. Thanks to Vera, Káča, and Černá Louže for making it happen this year!

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Gregor lab @gregorlab.bsky.social · 30/04/2026

Happy to be part of this story: Jan Famera and Lea M. Skultéty from Gymnázium Karla Čapka in Dobříš advanced to the next round of Students’ Professional Activities, Czech national high-school research competition, with work on muscular dystrophy performed in our lab. Huge congratulations!

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Gregor lab @gregorlab.bsky.social · 20/03/2026

Great @imgprague seminar by our PhD student Srikant Ojha @sojha148 on hepatic stellate cell #mechanosignaling and its potential for new therapeutic approaches in liver #fibrosis. Lab of Integrative Biology @Gregor_lab is leveling up 🚀

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Gregor lab @gregorlab.bsky.social · 31/12/2025

Our paper on the anti-cancer effects of the first-in-class plectin inhibitor plecstatin is out in @MolOncology! Great work by @OutlaZuzana & @Kosla_Jan. Collaborations with @Selma_OsMyers (@MedUniWien), Sam Meier (@univienna) & Lukas Frick (@UZH). Check at pubmed.ncbi.nlm.nih.gov/41467448/

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Gregor lab @gregorlab.bsky.social · 22/12/2025

It’s been an eventful year for all of us! Our Christmas party was a great reminder of the team spirit behind the science & we’re excited to take on the challenges of 2026. Merry Christmas & Happy New Year from the Laboratory of Integrative Biology!

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Gregor lab @gregorlab.bsky.social · 09/10/2025

At #WMS2025 in Vienna? Check out our PhD student Vera Getmanchuk-Zaporoshchenko’s poster on phenotyping a preclinical model of plectin-related LGMD. #LGMD #MuscularDystrophy"

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Gregor lab @gregorlab.bsky.social · 23/09/2025

Huge congrats to our PhD student, Piyush Bisht, for presenting his work on Flipper-TR probe applied to Circulating Tumor Cells at #Czechbioimaging's Imaging Principles of Life 2025 conference in Brno! He had amazing discussions and valuable feedback. Way to go, Piyush!" @imgprague.bsky.social

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Gregor lab @gregorlab.bsky.social · 03/09/2025

Two hours of tough work to make 2 minutes of science sparkle ✨ Today we helped popularize our #magnetogenetics manuscript by Gemperle Jakub for NUVR_CZ. Tune in to TV NOVA evening news!

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Gregor lab @gregorlab.bsky.social · 20/08/2025

“Cellfie: A triple-stained portrait of HeLa’s senescence” by Spoorthi Suresh Hiremath (@imgprague.bsky.social; ‪@gregorlab.bsky.social‬) has won the Prague @eurobioimaging.bsky.social Node Picture of the Month. Congrats Spoorthi!

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Gregor lab @gregorlab.bsky.social · 07/07/2025

Gamechanger for vesicle Control! We present an approach to remotely control endosomal distribution in living cells (even in #3Dmatrix) with high precision.

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Gregor lab @gregorlab.bsky.social · 25/06/2025

Huge congratulations to our PhD student Srikant Ojha for winning the Microscopic Picture of the Year 2024/2025 award! Well deserved!

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Gregor lab @gregorlab.bsky.social · 29/04/2025

30th Cytoskeletal Club was opened in Liblice on Monday, 28 April. The first day is complete - great keynote by Martijn Gloerich (@GloerichLab) from @UMCUtrecht on Mechanical control of epithelial cell division. More to come!

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Gregor lab @gregorlab.bsky.social · 27/04/2025

Great 2 days at MedUni Vienna hosted by @Selma_OsMyers from Institute of Medical Chemistry and Pathobiochemistry. Giving a seminar on our concept of targeting mechanical homeostasis in cancer. Great meeting the Lilli Winter and Osmanagic-Myers Labs. Evening with our mentor Gerhard Wiche.

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Gregor lab @gregorlab.bsky.social · 11/04/2025

Excited to share our new @elife.bsky.social in collaboration with @Schiller lab.: Dynamics of compartment-specific proteomic landscapes of hepatotoxic and cholestatic models of liver fibrosis doi.org/10.7554/eLif... #ECMatrix #chaperone #Clusterin #ECMresearch #Collagen #Integrin #AFM #Proteomics

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Gregor lab @gregorlab.bsky.social · 24/03/2025

Happy Monday... Happy to share the picture of our colleague Srikant Ojha winning EuBI Node Picture of the Month 2024/25 competition! (imcf.natur.cuni.cz/IMCF/picture...)

"A microscopic cage: The image has 2 channels: black, phalloidin (actin) and color, alpha smooth muscle actin. The structure shows an architectural masterpiece of actin-bundle caging the nucleus in activated primary hepatic stellate cells isolated from mice."

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Gregor lab @gregorlab.bsky.social · 21/03/2025

🐭 In vivo HCC models: Knocking out or inhibiting plectin in preclinical liver cancer models significantly reduced tumor growth & metastasis—supporting its crucial role in disease progression.

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Gregor lab @gregorlab.bsky.social · 21/03/2025

🔬 In vitro experiments: We found that plectin enhances colony formation, invasion, and mechanosignaling, making tumor cells more aggressive. Disrupting plectin weakens cytoskeletal integrity and reduces the ability of cancer cells to spread.

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Gregor lab @gregorlab.bsky.social · 21/03/2025

📊 HCC patient meta-analysis: Our data show that plectin is upregulated in HCC tumors, advanced TNM stages and correlates with poor patient prognosis. This suggests plectin is not just a bystander but a key player in liver cancer progression.

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Gregor lab @gregorlab.bsky.social · 13/03/2025

Hello! The Martin Gregor lab @imgprague is now on Bluesky! We will tweet about our #mechanobiology work, pretty microscopy images and videos and more. FOLLOW us!

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