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Matthew Wasco @gleason4plus5.bsky.social · 29/03/2026

Also, too many people equate an "abnormal" lab test flag (as it relates to the reference range) with an abnormality requiring further intervention.

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Kamran Mirza MD PhD @kmirza.bsky.social · 02/11/2025

Mia the Marvelous Lab Explorer is now available for pre-order 🥳🥳🥳 Dr. Mulder and I wrote this book to spark curiosity, inspire future scientists, and shine a light on the people whose work often goes unseen. a.co/d/iiIs46w cc: @shematologist.medsky.social

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Matthew Wasco @gleason4plus5.bsky.social · 23/05/2025

One of the greatest truths I have seen in the medical literature is this sentence in Up to Date about urine drug testing. In my experience, most docs understand there are limitations, but not the extent of them.

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Matthew Wasco @gleason4plus5.bsky.social · 01/05/2025

This is how people talk about AI in medicine too - it's always everyone else's specialty that is most at risk. Never yours.

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Matthew Wasco @gleason4plus5.bsky.social · 08/04/2025

This is a really good and informed article about the state of Pathology AI. Great to read something from a person who has actually made the effort to actually understand what a pathologist does. www.owlposting.com/p/what-happe...

owlposting.com

What happened to pathology AI companies?

4k words, 19 minutes reading time

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Matthew Wasco @gleason4plus5.bsky.social · 25/02/2025

In #GUPATH we talk about comedo necrosis in high grade prostate cancer being associated with intraductal spread - but not always - this is a lymph node metastasis, so no intraductal spread here!

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Matthew Wasco @gleason4plus5.bsky.social · 25/02/2025

Hello - The American Board of Pathology is soliciting nominations for a new trustee - as you can see in the posting there are no specific subspecialty qualifications or desires, we are just looking for someone who would make a good trustee. Please nominate! #pathsky abpath.org/2025/02/nomi...

abpath.org

ABPath Seeking Nominations for New Trustee

The American Board of Pathology (ABPath) is soliciting nominations to fill a Trustee position, effective January 1, 2026. We are seeking a nominee with demonstrated executive leadership and/or board g...

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Matthew Cortland (they) @matthewcort.land · 24/01/2025

The RFK Jr. confirmation hearing has been scheduled for 1/29/25. The nomination is on shaky ground. Here's the call to action: Reach Out To Your Senators and Urge Them To Oppose RFK Jr's nomination to be HHS Secretary Here's how to do that, step-by-step:

patreon.com

CTA: RFK Jr Nomination Hearing Scheduled - Time To Reach Out To Your Senators | Matthew Cortland

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International Society of Urological Pathology @intsocuropath.bsky.social · 08/01/2025

📢 Exciting news! @intsocuropath.bsky.social and @GU_Path_Society are hosting an Expert Consultation Conference on IDC-P during #USCAP2025! 🗓 Saturday, March 22, 2025 ⏰ 1-5 PM 📍 Boston (in-person, free for members) 🔗 Register: www.eventbrite.com/e/expert-con...

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Dan Berney @danberney.bsky.social · 03/01/2025

Have a look at the FREE TO READ! Annual Review Issue in Histopathology’s #hempath. ( Histopathology will shortly follow me here!) onlinelibrary.wiley.com/toc/13652559...

onlinelibrary.wiley.com

ANNUAL REVIEW ISSUE: HAEMATOLYMPHOID MALIGNANCIES: BEYOND THE CURRENT CLASSIFICATIONS: Histopathology: Vol 86, No 1

Click on the title to browse this issue

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AndrewFolpe @folpe-mn-st.bsky.social · 23/12/2024

#PathSky This one definitely needs more than 4 images, so go to the Comments too. 65F, iliac crest lesion. The original pathologists quite reasonably considered an epithelioid hemangioendothelioma, although it was CAMTA1-negative.

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AndrewFolpe @folpe-mn-st.bsky.social · 20/12/2024

#PathSky 15F, thumb mass. There are no relevant positive immunostains. However, FISH for DDIT3 amplification (not rearrangement) is positive. This is an excellent example of a GLI1-amplified sarcoma. This is a great paper from the MSKCC group. pubmed.ncbi.nlm.nih.gov/38934567/

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Alexander Nader, Einschauer, Pathologist @alexnader.eurosky.social · 17/12/2024

We should start a discussion about reducing workload without reducing quality. Molpath in Barrett's without dysplasia us a good starting point...

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Lauren Smith, MD, HEC-C @lbsmithmd.bsky.social · 15/12/2024

Skin/subcutaneous tissue. #pathsky #medsky what is your diagnosis. Low power pic is all you should need 💪🏽

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Katrina Collins || Pathologist @katcollmd.bsky.social · 12/12/2024

#slidearchiveseries SMARCB1 deficient renal medullary carcinoma #gupath #pathsky #pathoutpic 🩸 young pts with sickle cell trait 🔬 cribriform, reticular, nested growth 🎨 PAX8, broad spectrum CKs, CEA, p53 ⚠️ OCT3/4 ➕ (50%), pitfall with GCT 🔑 SMARCB1 / INI1 inactivation

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Matthew Wasco @gleason4plus5.bsky.social · 12/12/2024

If I ran CMS, pathologist coding for lipomas would change. Sure, small lipomas can be 88304, even 88302 as a compromise, but larger, subfascial lipomas should not in any world be an 88304. These are very difficult specimens both for the histo lab and for us pathologists. #pathsky

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Matthew Wasco @gleason4plus5.bsky.social · 11/12/2024

I talk to docs about this all the time - a reference interval is not a "normal" range, it's a population based statistic which applies to healthy people (many people getting blood drawn would be rejected from reference range studies). "Abnormal" does not always imply disease (and vice versa)

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Eric Topol @erictopol.bsky.social · 11/12/2024

Our blood tests are interpreted by average reference values. That's missing a lot of rich information! Each person has their own tightly regulated setpoints. One healthy person's complete blood count setpoint can be differentiated from 98% of other healthy adults. www.nature.com/articles/s41...

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Matthew Wasco @gleason4plus5.bsky.social · 10/12/2024

Amazing what can happen in a chronic infection in a toe - distal part here was nearly obliterated by chronic infection, repair process starting re-covering the bone with the adjacent skin, and grew into the actual bone. All benign, amazing! #pathsky

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Matthew Wasco @gleason4plus5.bsky.social · 10/12/2024

I mean, I know this has happened and this kind of thing is the reason why CLIA exists, but it's still shocking to see it. #pathsky

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AndrewFolpe @folpe-mn-st.bsky.social · 20/11/2024

#PathSky I try not to talk about it, but sometimes I look at bone cases. Lytic sacral lesion, 69M. Among the many IHC it was sent with, CD31 and KIT were diffusely positive, but other endothelial and GIST markers were negative. Dx? Anything else you’d like?

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Matthew Wasco @gleason4plus5.bsky.social · 21/11/2024

Scrotal calcinosis - such a beautiful entity #pathsky #gupath

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Matthew Wasco @gleason4plus5.bsky.social · 20/11/2024

I called this a tonsillar fibroma since I didn't know what else to call it, but it's a great section! Almost like the tonsil has its own uvula. #pathsky #pathology

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Matthew Wasco @gleason4plus5.bsky.social · 18/11/2024

A cooking competition where the cleanup is part of the time you get to complete the meal.

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Matthew Wasco @gleason4plus5.bsky.social · 15/11/2024

Love when this particular therapy dog visits (Koda).

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Matthew Wasco @gleason4plus5.bsky.social · 12/11/2024

Since I need a first post, this is an image of a pulmonary embolus, stained with a Movat (pentachrome) stain). The stain doesn't tell you anything but it's kind of cool. #pathology

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