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Gerald Denis

@gdenisboston.bsky.social
846 followers 281 following 89 posts

Cancer researcher dedicated to improving health equity. Canadian. This page focuses on science, medicine and policy. On Threads I focus on my fitness journey: @gdenisboston

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Gerald Denis @gdenisboston.bsky.social · 20/11/2025
The first episode of my new podcast is up. Please give it a listen. zencastr.com/The-Fifth-Co...
zencastr.com
The Fifth Column
The Fifth Column is a weekly wartime journal documenting the erosion of the American Republic.  Through interviews and creative commentary, we aim to build a space for community, for imagination, and...
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Gerald Denis @gdenisboston.bsky.social · 08/11/2025
Appalling
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Mother Jones @motherjones.com · 26/08/2025
The DOGE-triggered brain drain has destroyed government science, endangered research, and left America fading to black.
motherjones.com
When it comes to Trump's brain drain, “the damage is already done”
How the DOGE-triggered attack on government research left America in the dark.
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Gerald Denis @gdenisboston.bsky.social · 26/08/2025
www.nature.com/articles/s42... Excited to announce the most recent paper from my lab. Ennis and coauthors model the breast cancer microenvironment in obesity-driven diabetes and show that anti-tumor immunity is profoundly suppressed compared to metabolically healthy #breastcancer.
nature.com
Plasma exosomes from individuals with type 2 diabetes drive breast cancer aggression in patient-derived organoids - Communications Biology
Exosomal signaling from type 2 diabetes alters tumor–immune crosstalk, driving immunosuppression and tumor aggressiveness in breast cancer organoids through expansion of dysfunctional T cells and activation of invasive programs.
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Gerald Denis @gdenisboston.bsky.social · 07/08/2025
My new interview with WGBH just posted. I talk about the deepening crisis at #NIH in #medical research funding and the devastating impact on #cancer research of #Trump administration priorities.  youtu.be/iKkum-pAoYA
youtu.be
Science for the Public: Save Medical Science! Guest: Gerald Denis, PhD.
YouTube video by Belmont Media Center
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Anonymous @youranoncentral.bsky.social · 30/07/2025
Tsunami warning for most pacific coast nations; 8.8 earthquake reported in Russia. Stay informed, and stay safe out there.
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Nick Walden Poublon @nwpinpdx.bsky.social · 10/07/2025
Cherry farmers in my district in The Dalles are leaving hundreds of tons of cherries to rot because workers are too afraid of ICE raids to come harvest. This is what happens when cruelty becomes policy. It hurts everyone. #orpol #immigration #agriculture www.kptv.com/2025/07/10/c...
kptv.com
Cherry farmer in The Dalles says ICE raid fears costing him workforce, profits
One cherry farm in The Dalles has been forced to leave tons of fruit on the branches over the lack of workforce.
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Gerald Denis @gdenisboston.bsky.social · 09/07/2025
Thrilled to report new findings from our #NIH supported research on breast cancer. Obesity/ #diabetes are common and increasing across America. We report that blood #exosomes in #obesity drive progression and metastasis of triple negative #breastcancer. bmccancer.biomedcentral.com/articles/10....
bmccancer.biomedcentral.com
Plasma exosomes in insulin resistant obesity exacerbate progression of triple negative breast cancer - BMC Cancer
Breast cancer, the most common cancer among women worldwide, continues to pose significant public health challenges. Among the subtypes of breast cancer, triple-negative breast cancer (TNBC) is partic...
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Chris Geidner @chrisgeidner.bsky.social · 15/06/2025
I missed that Jeff Bezos sold the Post to Donald Trump directly.
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The Lincoln Project @lincolnproject.us · 06/06/2025
81 years ago, America's bravest generation stormed the beaches of Normandy in hopes of freeing Europe from the clutches of a brutal authoritarian. Today, we face authoritarianism on our shores. We owe it to ourselves, our country, and that great generation to fight for freedom here at home.
youtube.com
The Boys of Pointe du Hoc
YouTube video by The Lincoln Project
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Ferric Fang, MD @fangferric.bsky.social · 29/05/2025
Two Harvard economists forecast the impact of the administration’s proposed NIH budget cuts- stunning losses in new therapies, life expectancy, and economic output with a “social cost 16 times greater than the savings the administration is attempting to achieve." jamanetwork.com/journals/jam...
jamanetwork.com
Cutting the NIH—The $8 Trillion Health Care Catastrophe
This JAMA Forum discusses the recent budget cuts to National Institutes of Health (NIH), the effects of these cuts on scientific research and health of individuals in the US, and the prospects for cha...
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Congresswoman Jasmine Crockett @crockett.house.gov · 27/05/2025
NPR is suing Trump. Why? Because he slashed their funding just for doing their job—which is political retaliation. He’s trying to silence public media because they don’t bow down to his ego. News flash: the First Amendment doesn’t disappear just because you don’t like the coverage, Donnie.
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Ferric Fang, MD @fangferric.bsky.social · 23/05/2025
"We condemn the US government's use of extortion to coerce independent institutions to act in accordance with the administration's preferences. . . it's punishing of researchers unrelated to the charges against their universities. . . (and) its short-sighted and senseless cuts to basic research."
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Neil deGrasse Tyson @neildegrassetyson.com · 19/05/2025
If a foreign adversary snuck into our Federal budget and cut science research and education the way we’re cutting it ourselves — strategically undermining America’s long-term health, wealth, and security — we would likely consider it an act of war.
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Congresswoman Jasmine Crockett @crockett.house.gov · 14/05/2025
Marjorie, I know the truth confuses you and facts ain’t your strong suit—so let me break it down real slow: George Floyd didn’t die from drugs. He died because Derek Chauvin knelt on his neck for 9 minutes. That’s called murder.
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Gerald Denis @gdenisboston.bsky.social · 10/05/2025
Excited to share new #NIH funded research showing that #insulin resistance drives aggressiveness of #breastcancer. Women with #obesity and metabolic complications have higher risk of #metastasis. Model systems show we should consider this risk in #TNBC. #NCI www.biorxiv.org/content/10.1...
biorxiv.org
Plasma Exosomes in Insulin Resistant Obesity Exacerbate Progression of Triple Negative Breast Cancer
Breast cancer, the most common cancer among women worldwide, continues to pose significant public health challenges. Among the subtypes of breast cancer, triple-negative breast cancer (TNBC) is partic...
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Christophe Veltsos @drinfosec.bsky.social · 09/05/2025
From Twitter "You know how they say the 3rd generation to inherit wealth squanders it? That is what we are doing with public health right now. People living with all the benefits of it are dismantling it because they think it's just natural to not have constant disease..." OP: x.com/wonderartsy/...
You know how they say the 3rd generation to inherit wealth squanders it? That is what we are doing with public health right now. People living with all the benefits of it are dismantling it because they think it's just natural to not have constant disease and death... about to FIND OUT aren't we?
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Gerald Denis @gdenisboston.bsky.social · 01/05/2025
A placebo arm for a randomized clinical trial of measles vaccine is profoundly unethical and wrong because it will cause avoidable harm. Such a no brainer. We are being led by an amoral idiot.
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💙❤️💙Mia💙❤️💙 @mommamia.bsky.social · 01/05/2025
🚨🚨🚨 This is serious. PLEASE READ: 🚨🚨🚨 RFK Jr plans to EXPERIMENT ON OUR CHILDREN. “…Would subject all new vaccines, including vaccines for children & vaccines for WELL RESEARCHED DISEASES like measles & polio to placebo testing…they would take a bunch of kids, divide them into two groups 1/3
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Gerald Denis @gdenisboston.bsky.social · 01/05/2025
Excited to share a revised pre-print of Christina Ennis‘s work: obesity-driven #diabetes reveals immune dysfunction and tumor aggressiveness in #breastcancer patient-derived #organoids. We preserved primary tumor immune infiltrates for the first time. Thanks to #NCI. www.biorxiv.org/content/10.1...
biorxiv.org
Plasma exosomes from individuals with type 2 diabetes drive breast cancer aggression in patient-derived organoids
Women with obesity-driven diabetes (T2D) are predisposed to more aggressive breast cancers, yet patient metabolic status does not fully inform current standards of care. We previously identified plasm...
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Acyn @acyn.bsky.social · 01/05/2025
Raskin: Our chairman… How does one go from a libertarian railing about the deep state and the fbi and the doj coming down on the rights of the people to becoming a supine submissive authoritarian who votes against providing basic due process rights for the people against the government?
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Gregg Gonsalves @gregggonsalves.bsky.social · 30/04/2025
The architect of #NIH cuts is Russell Vought whose own daughter is alive today because of advances in treating cystic fibrosis, brought to us, to the Vought family, by NIH. 1/ www.motherjones.com/politics/202...
motherjones.com
Project 2025 is gutting medical funding that helped Russell Vought's own kid
Its architect's daughter has cystic fibrosis—and benefits from a "miracle drug" backed by an agency he's attacking.
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Gerald Denis @gdenisboston.bsky.social · 30/04/2025
“The cruelty is the point.”
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Gerald Denis @gdenisboston.bsky.social · 28/04/2025
New Substack. open.substack.com/pub/geraldvd...
open.substack.com
Letters from a Boston scientist 11
It’s the margins, not the mainstream, that we should worry about.
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William C Phelps, PhD @wcphelps.bsky.social · 20/04/2025
A compelling letter from Nobel Laureate, William Kaelin, MD about the looming loss of US leadership in science and innovation. 🧪 www.amjmed.com/article/S000...
amjmed.com
Killing the Science Golden Goose
In the 1970’s I was probably one of the last American high school students who was told that if you wanted to go to medical school, you should learn to speak German. This was because in the late 19th ...
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Gerald Denis @gdenisboston.bsky.social · 21/04/2025
New Substack. open.substack.com/pub/geraldvd...
open.substack.com
Letters from a Boston scientist 10
Exit, voice, or loyalty?
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Alt NIH Bluesky 🧪 @altnih4science.bsky.social · 18/04/2025
This is a huge deal. This is a Senator using his power in a non-traditional way: tget to El Salvador, get to see Kilmar, and get pics of both of them out. For Congress right now it’s not about speeches on the floor or business as usual. Good on the Senator for doing this.
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Timothy Snyder @timothysnyder.bsky.social · 16/04/2025
By "free speech," the Americans mean creating a media environment in your country dominated by American digital fascism preparatory to right-wing regime change. Vance essentially said as much in Munich. Give in now, forget about sovereignty later. www.independent.co.uk/news/uk/poli...
independent.co.uk
Starmer told to accept Trump ‘free speech’ agenda to win trade deal
‘Good chance’ of agreement, says JD Vance – but sources say his concerns over Britain’s hate speech laws ‘are still a red line’
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NPR @npr.org · 16/04/2025
All 27 scientists at this CDC lab were told their duties were "unnecessary," and now viral outbreak investigations have been halted.
npr.org
In the middle of a hepatitis outbreak, U.S. shutters the one CDC lab that could help
All 27 scientists at this CDC lab were told their duties were "unnecessary," and now viral outbreak investigations have been halted
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Gerald Denis @gdenisboston.bsky.social · 16/04/2025
Just published a new Substack, inspired by Tim Snyder’s warning about state terror coming to America. @timothysnyder.bsky.social open.substack.com/pub/geraldvd...
open.substack.com
Letters from a Boston scientist 9
State terror is bad for everyone’s health.
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Timothy Snyder @timothysnyder.bsky.social · 15/04/2025
"the president defied a Supreme Court ruling to return a man mistakenly sent to a gulag... and spoke of sending Americans to foreign concentration camps. This is the beginning of an American policy of state terror, and it has to be identified as such to be stopped" snyder.substack.com/p/state-terror
snyder.substack.com
State Terror
A brief guide for Americans
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Alt NIH Bluesky 🧪 @altnih4science.bsky.social · 14/04/2025
We called out Harvard in the past for inaction. So now we are happy to speak out with praise. This is a major step forward. It’s not just a lack of capitulation. It’s an aggressive effort leaning into public comms — exactly what is needed. Bravo to Harvard 👏
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PoliticsGirl @politicsgirl.bsky.social · 13/04/2025
Oof. We’ve fallen so far, so fast.
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Timothy Snyder @timothysnyder.bsky.social · 11/04/2025
This is how Kaganovich talked about Stalin.
Screenshot of a post from Stephen Miller's twitter account, @StephenM
"You have been watching the greatest economic master strategy from an American President in history."
3:29PM, 4/9/25, 487k views, 2.2k comments, 4.5k retweets, 26k likes
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Alt NIH Bluesky 🧪 @altnih4science.bsky.social · 10/04/2025
This is Orbanism, brought to America. It’s a fascist takeover of US universities, stripping free speech, because the Trump regime wishes to control universities, end free thought and fight truth. We fight now, inside and outside NIH, or US science becomes Soviet science.
wsj.com
Exclusive | Trump Administration Wants to Install Federal Oversight of Columbia University
In an unusual move, the government is aiming to legally bind the school to changes as they negotiate over federal funding
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Gerald Denis @gdenisboston.bsky.social · 10/04/2025
I was interviewed by Yvonne Stapp of ‘Science for the Public’ about the funding crisis at #NIH and for #cancer research at #NCI. Link to WGBH Boston. www.wgbh.org/forum-networ...
wgbh.org
Cancer Research: How It Works and Why It's Crucial Today
Professor Gerald Denis, a molecular oncologist at Boston Medical Center, investigates a range of cancers and their causes. Some of his important studies include prostate cancer and breast cancer, whic...
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Atul Gawande @agawande.bsky.social · 08/04/2025
USA led the world in expertise stopping HIV, incl preventing mother to child transmission. But DOGE has now dismissed every global prevention expert at USAID, CDC, & State Dept. The risk is insane: Resurgent HIV & 500K child deaths by 2030. www.nytimes.com/2025/04/08/h...
nytimes.com
Who Will Care for Infants With H.I.V. Overseas? (Gift Article)
The consequences of mother-to-child transmission can be enormous, a new study suggests. But the U.S. has dismissed experts working to solve the problem.
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Gerald Denis @gdenisboston.bsky.social · 06/04/2025
Raskin is on fire 🔥
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God @thegodshow.com · 25/03/2025
We’re getting so close
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Molly Jong-Fast @mollyjongfast.bsky.social · 15/03/2025
Here’s Elon cutting pediatric brain cancer research 👇🏻
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Sarah Szalavitz💡 @dearsarah.bsky.social · 12/03/2025
Mahmoud Khalil’s abduction is a fascist move — and universities must respond Schools across the United States have a choice: defend their students against Trump or be complicit in his crimes. flip.it/JYcsj_
flip.it
Universities must respond to Mahmoud Khalil’s fascist abduction
U.S. schools have a choice: defend their students against Trump or be complicit in his crimes.
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Andy Kaczynski @kfile.bsky.social · 10/03/2025
They’ve lost Ann Coulter on this
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Leah Greenberg ❌👑 @leahgreenberg.bsky.social · 10/03/2025
BRB, checking the history books to find out whether “tyrant starts redefining peoples’ citizenship status” usually ends well for the Jews
ADL twitter statement offering support for wildly unconstitutional action to detain and strip status from a green card holder for pro-Palestine protests
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Daniel Goldman @danielsgoldman.dg4ny.co · 10/03/2025
This was always the risk with Gabbard and Patel at the head of our intelligence gathering. We not only will lose our own sources who won’t trust them, but we will lose intelligence from our close allies. This makes a terrorist attack on US soil much more likely.
dailymail.co.uk
Britain urged to form breakaway 'Four Eyes' alliance without the US
Some in the defence establishment are now suggesting forming a sub-group in the existing 'Five Eyes' alliance to allow intelligence sharing without a US veto.
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Alex Wild @alexwild.bsky.social · 08/03/2025
Science is under assault because Trumpists are illegally purging labs, deleting data, and censoring research. This is actual fascism. It’s not “cuts”. Don’t normalize what they are doing.
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Margaret Crane, PhD @margaretcrane.bsky.social · 06/03/2025
Good to see NIMH Board of Scientific Counselors standing up against new NIH policies. We need more of this from senior leaders!
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Gerald Denis @gdenisboston.bsky.social · 06/03/2025
Excited to share our most recent results in cancer research supported by #NIH. We found that obesity-driven insulin resistance promotes breast cancer metastasis. We must address this public health crisis because >120 million Americans are diabetic/prediabetic. aacrjournals.org/mcr/article-...
aacrjournals.org
Insulin Resistance Increases TNBC Aggressiveness and Brain Metastasis via Adipocyte-derived Exosomes
Abstract. Patients with triple negative breast cancer (TNBC) and comorbid Type 2 Diabetes (T2D), characterized by insulin resistance of adipose tissue, have higher risk of metastasis and shorter survi...
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Stand Up for Science! @standupforscience.net · 06/03/2025
"In an unprecedented move, the US National Institutes of Health (NIH) has begun mass terminations of research grants that fund active scientific projects because they no longer meet 'agency priorities'" www.nature.com/articles/d41...
nature.com
Exclusive: NIH to terminate hundreds of active research grants
Studies that touch on LGBT+ health, gender identity and DEI in the biomedical workforce could be terminated, according to documents obtained by Nature.
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Max Kozlov @maxkozlov.bsky.social · 06/03/2025
“It’s extremely alarming that grants that have been vetted by the scientific community and deemed important and impactful to understand the world are now being cancelled because of political ideology,” says @lkfazio.bsky.social. “This is direct censorship of scientific research.”
nature.com
Exclusive: NIH to terminate hundreds of active research grants
Studies that touch on LGBT+ health, gender identity and DEI in the biomedical workforce could be terminated, according to documents obtained by Nature.
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Michael Hendricks 🇨🇦 @michaelhendricks.bsky.social · 05/03/2025
He's a smug contrarian whose covid predictions were off by 2 orders of magnitude, and yes, he wants revenge for that humiliation.
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