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Sharp wave ripples (SWRs) reactivate hippocampal activity patterns during memory consolidation, but whether they recruit cFos engram cells is unclear. We tagged CA1 neurons activated during sequential...

BackgroundWhile Alzheimer’s disease (AD) is well known for progressive memory impairment, less is understood about how amyloid pathology affects flexible upd...

Postdoctoral Scientist (f/m/d)

Molecular Psychiatry - Distinct roles for MNK1 and MNK2 in social and cognitive behavior through kinase-specific regulation of the synaptic proteome and phosphoproteome

dos Santos Correa et al. show that exposure to a stressful context promotes the acquisition of rescue behavior in mice and that the dorsal hippocampus is required for this learning. Calcium imaging re...

Chaire d'excellence - développement, évolution moléculaire et cellulaire des circuits cérébraux // Full Professor or Associate Professor Chair of Excellence Development, Molecular and Cellula...

The hippocampal formation is central for the learning and consolidation of spatial memories. While it is known that the high-frequency oscillations, called sharp wave ripples, play a critical role for...

GluA2 is a key subunit of AMPA receptor ion channels that is abundantly expressed in the vertebrate brain. Posttranscriptional Q/R editing of GluA2 renders AMPARs nearly impermeable to calcium ions, w...

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LiveMore and more people are suffering from stress and depression. To effectively help them, studies using animal models are indispensable. But how can mental health be studied in animals? And what in...