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GalhardoLab

@galhardolab.bsky.social
58 followers 80 following 28 posts

Vasco Galhardo. Neuroscientist, Pain Research. Director PhD Program Neuroscience, University Porto. Group Leader i3S. Era-Net NEURON Ambassador.

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Megan Carey @megancarey.bsky.social · 08/07/2026
Congratulations to Tatiana Silva @ntatianasilva.bsky.social on winning this award for her 2024 paper, and thank you @spneurociencias.bsky.social for the recognition! 🎉
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Oded Rechavi @odedrechavi.bsky.social · 27/04/2026
It’s not review unless it comes from the Review region of France, otherwise it’s just sparkling criticism
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See Through Canoe @seethroughcanoe.bsky.social · 01/09/2025
A sea turtle surfacing by a MASSIVE school of rays near Clearwater, Florida a couple days ago. Another post into the BluSky void. Maybe 2 or 3 people will see this one and my time won't have been wasted. I'll keep trying a little longer. #nature #animals #amazing #wildlife #awesome #ocean
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Oded Rechavi @odedrechavi.bsky.social · 15/07/2025
The first person to sequence a whale at single cell resolution is guaranteed a CNS paper. Then you'd need to sequence a family of whales.
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George Conway ⚖️🇺🇸 @gtconway.bsky.social · 11/07/2025
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George Conway ⚖️🇺🇸 @gtconway.bsky.social · 31/05/2025
That would be awful. Don’t share this.
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George Conway ⚖️🇺🇸 @gtconway.bsky.social · 27/05/2025
Read the speech for yourself: commencement.news.wfu.edu/2020s/c2025/... ht: @brianstelter.bsky.social
commencement.news.wfu.edu
2025: Scott Pelley - Commencement News Archive
Good morning, everybody. What a beautiful day. What a beautiful North Carolina day for a graduation. Incredible. Thank you, President Wente, Provost Gillespie, members of the Board of Trustees and Kat...
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Ardem Patapoutian @ardemp.bskyverified.social · 20/04/2025
In science, we don’t give negative data nearly enough love. Showing with genetic precision that CGRP and Substance P aren’t needed for different kinds of acute and chronic pain? That’s huge.
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Drew Schreiner @schreinerdrew.bsky.social · 21/03/2025
Very elegant work, on a theme near and dear to me! Animals are individuals and their unique experiences matter for behavior and circuit recruitment/computation! www.sciencedirect.com/science/arti... (these two links are old stuff from me, beautiful new work from @marinopagan.bsky.social below!)
nature.com
Information normally considered task-irrelevant drives decision-making and affects premotor circuit recruitment - Nature Communications
Prior experience is used by the brain to guide adaptive behaviour during decision making. Here, the authors show that mice also selectively use information learned through recent and longer-term exper...
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Carsten Schulte @carstenschulte4.bsky.social · 20/03/2025
The fact that we allow this absurd scientific publishing system to persist for decades, together with the insanely high percentage of precarious jobs in the academic system, proves we are not so smart after all...
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allen institute @alleninstitute.org · 19/03/2025
New hope for families battling Dravet Syndrome. Scientists have developed a new gene replacement therapy that could improve treatments for a rare and life-altering form of epilepsy. 🧵 #Neuroskyence #DravetSyndrome
Image of cells impacted by Dravet Syndrome with the words "Breakthrough Dravet Syndrome gene therapy in mice brings new hope to families. Scientists successfully replace defective gene to alleviate symptoms without side effects."
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International Association for the Study of Pain (IASP) @iasp.bsky.social · 19/03/2025
In this week’s #PAIN Featured Image, Biggs et al. depict the functional connectivity of amygdala and hippocampus seed regions. Maps show FDR-corrected results. Cluster colors indicate seed region and clusters, and those that survived Bonferroni correction are circled. bit.ly/41eaqSo
PAIN 19 Mar 2025
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Dr. Ali Barry @aliibarry.com · 18/03/2025
Nice paper acceptance to start the week ⬇️ #PainResearch
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Ted Price @tedpricethepainguy.bsky.social · 17/03/2025
and while you are at it, read this nice piece on mRNA vaccines for pancreatic treatment: www.mskcc.org/news/can-mrn... still early days on that, but what I have read about the approach is truly remarkable. Pancreatic cancer is a hellish disease.
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Rui Costa @ruimcosta.bsky.social · 14/03/2025
OpenScope has been a game-changer in neuroscience and served as a shining example of #OpenScience. I'm incredibly proud of how this program has allowed important questions about the brain to be pursued and shared with the world.
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Rui Costa @ruimcosta.bsky.social · 14/03/2025
The brain shapes our identity, memories, and emotions. Understanding it is key to combating brain diseases affecting over 3 billion people. #BrainAwarenessWeek highlights the @alleninstitute.bsky.social's groundbreaking work. Let's raise awareness & inspire action for brain health. #ScienceMatters
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PAIN @painthejournal.bsky.social · 12/03/2025
Jane Yang et al.’s review finds that preclinical testing of NaV1.7-selective inhibitors aligned poorly with clinical testing, highlighting treatment regimen and choice of pain model as areas for improvement. Learn more in #PAIN bit.ly/3X2NO4P
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Drew Schreiner @schreinerdrew.bsky.social · 12/03/2025
Proud to have contributed to @jiaxuanqi.bsky.social's masterpiece out @nature.com! She shows that dopamine transients track the learned quality of song during juvenile learning and that dopamine release is driven not just by VTA firing, but by a local cholinergic mechanism! (1/x)
nature.com
Dual neuromodulatory dynamics underlie birdsong learning - Nature
Dopamine release in the basal ganglia of the zebra finch is driven by neurons associated with reinforcement learning and by cholinergic signalling, and tracks performance quality during long-term lear...
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Blake Richards @tyrellturing.bsky.social · 11/03/2025
Dendrite specific linking of memories over time - a cool extension of the work from @sjo09.bsky.social, @denisejcai.bsky.social, and others: www.nature.com/articles/s41... #neuroscience 🧪
nature.com
Compartmentalized dendritic plasticity in the mouse retrosplenial cortex links contextual memories formed close in time - Nature Neuroscience
Sehgal et al. show that branch-specific dendritic plasticity mechanisms in the retrosplenial cortex link memories acquired close in time such that, unlike independent memories, linked memories are enc...
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Jeremy Berg @jeremymberg.bsky.social · 11/03/2025
I have confirmation from several sources now that all T32s, many F30s and F31s, and most or all Center awards (P30, P50) have been terminated at Columbia. This is quite damaging to research and to individuals. This is pure terrorism and cannot be legal. But litigation will take time...
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 10/03/2025
Accumulation of virtual tokens towards a jackpot reward enhances performance and value encoding in dorsal anterior cingulate cortex www.biorxiv.org/content/10.1101/202…
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Ted Price @tedpricethepainguy.bsky.social · 10/03/2025
It is important for people to see this graph/data. #NIH is the irreplaceable leader of USA leadership in biomedical discovery and development of new therapeutics.
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Chise @sailorrooscout.bsky.social · 09/03/2025
THIS IS HUGE! Researchers at Stanford University have developed a dual-antibody treatment that remains effective against ALL SARS-CoV-2 variants by targeting a less-mutable part of the virus. This breakthrough could lead to longer-lasting therapies that OUTPACE viral evolution. 🧪🧵⬇️
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Eric Topol @erictopol.bsky.social · 10/03/2025
Who funds biomedical research? @nature.com www.nature.com/articles/d41...
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Carlos Ribeiro @ribeirocarlitos.bsky.social · 10/03/2025
Wir brauchen einen “dreifachwumms”! Look at where the EU is (at the end of the chart) and tell me we could not do better.. This also shows you what a loss to science it was when the UK left the EU. Let’s work together.
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Ardem Patapoutian @ardemp.bskyverified.social · 08/03/2025
Finally! www.nytimes.com/2025/03/08/s...
nytimes.com
Stand Up for Science Rally Sees Mix of Science, Politics and Anxiety
Thousands of protesters gathered in Washington for Stand Up for Science, a rally in response to President Trump’s federal-funding and job cuts.
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Center for Advanced Pain Studies @utdpaincenter.bsky.social · 07/03/2025
✨ #FluorescenceFriday ✨ Check out this beautiful image of a stained spinal cord! Neurons (magenta) microglia (cyan), and nuclei(blue). 🧠🔬 #Neuroscience #ScienceArt #MicroscopyMagic #CellularBeauty #ResearchLife #painneuroscience
Stained image of a spinal cord, Neurons (magenta) microglia (cyan), and nuclei(blue)
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International Association for the Study of Pain (IASP) @iasp.bsky.social · 07/02/2025
Payne et al. find that menstrual pain severity, interference, and cumulative menstrual pain exposure were associated with functional connectivity of 3 key brain networks in adolescent girls with menstrual pain. Learn more in #PAIN bit.ly/40epspO
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International Association for the Study of Pain (IASP) @iasp.bsky.social · 12/02/2025
Now in #PainReports: “Dopamine dynamics in chronic pain: music-induced, sex-dependent, behavioral effects in mice” by Flores-García et al. bit.ly/4hiDlus
Pain Reports Featured Image
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International Association for the Study of Pain (IASP) @iasp.bsky.social · 17/02/2025
Qian Xu et al.’s in vivo calcium imaging study shows that spinal cord stimulation inhibited the activation of superficial neurokinin 1 receptor-positive neurons, unraveling a new mechanism for spinal cord stimulation-induced analgesia. Learn more in #PAIN bit.ly/40n0Viq
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Migraine Science Collaborative (MSC) @migrainecollab.bsky.social · 19/02/2025
Did you know that the #pain system works differently in men vs. women, at the cellular and molecular level? This is particularly true of #migraine pain. This new MSC editor's pick is an interesting animal study exploring these sex differences. #painresearch migrainecollaborative.org/papers/chron...
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International Association for the Study of Pain (IASP) @iasp.bsky.social · 21/02/2025
In a new editorial from Editor-in-Chief of PAIN @karenddavis.bsky.social reaffirms the journal’s commitment to considering #diversity, #DEI, and #GenderIdentity in pain research and management. bit.ly/3D5WgJO 
DEI Position
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International Association for the Study of Pain (IASP) @iasp.bsky.social · 21/02/2025
This week’s #PAIN Featured Image summarizes the promises and challenges of digital therapeutics (DTx) for behavioral chronic pain management. Learn more in Eccleston et al.’s new paper bit.ly/4hVK0uh
PFI 19 Feb 2025.png
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David Seminowicz @daspainbrain.bsky.social · 09/01/2025
check out this short journal club article and pain expectation by my grad student and @phivph.com www.jneurosci.org/content/45/2...
jneurosci.org
Pain Expectation Effects Are Predicted by Emotion Rather Than Precision
Pain is a universal subjective experience that is influenced not only by the objective intensity of the sensory stimulus but also by multiple internal factors, such as expectations and emotions (Melza...
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William Zempsky @kidspainmd.bsky.social · 12/01/2025
If you could only read one article about chronic pain read this #painresearch www.nytimes.com/2025/01/12/m...
nytimes.com
Chronic Pain Afflicts Billions of People. It’s Time for a Revolution.
As many as two billion people suffer from it — including me. Can science finally bring us relief?
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Rui Costa @ruimcosta.bsky.social · 07/01/2025
An important moment in our brain science work. We're closer to understanding aging and why so many brain diseases occur during advanced age – and what we can do to mitigate the impacts.
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Theanne Griffith, PhD 🇧🇧👩🏽‍🔬🇭🇷 @doctheagrif.bsky.social · 08/01/2025
Thrilled to share the most recent pub from the Griffith Lab! We show that sodium channels play unique roles in proprioceptive encoding. We also found some really cool effects on skeletal muscle, and a dev dependent role for Nav1.6 in proprioceptive spinal circuits www.science.org/doi/10.1126/...
science.org
Differential encoding of mammalian proprioception by voltage-gated sodium channels
Voltage-gated sodium channels differentially encode mammalian proprioception via distinct cellular localization patterns.
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Imaging Neuroscience @imagingneurosci.bsky.social · 02/01/2025
New paper in Imaging Neuroscience by Christopher Cover, Alexander J. Poplawsky, et al: Awake rodent fMRI: Gradient-echo echo planar imaging versus compressed-sensing fast low-angle shot direct.mit.edu/imag/article...
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Daniel P. Moriarity @dpmoriarity.bsky.social · 04/01/2025
"A study of federally funded research projects in the United States estimated that principal investigators spend on average about 45% of their time on administrative activities related to applying for and managing projects rather than conducting active research" www.pnas.org/doi/10.1073/...
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Daniela Barillà @danielabarilla.bsky.social · 10/11/2024
Can colleagues amplify this appeal to journals and journal editors to open accounts on Bluesky, please? @MicrobioSoc @TrendsMicrobiol @CellCellPress @JBacteriology @jbiolchem @Nature @ScienceMagazine @PNASNews @MolMicroEditors @NAR_Open @NatureMicrobiol @NatureComms @ASMicrobiology 🙏 🦠🧪🧫🧬
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Morgan J Freeman @mjfree.bsky.social · 20/12/2024
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GalhardoLab @galhardolab.bsky.social · 20/12/2024
Happy to share our newest paper on PAIN journal. Following our recent papers on neuropathy-induced disruption of mPFC, hipp and NAcc, Helder Cardoso-Cruz (non bluesky) tackled the lateral habenula using optogenetics and electrophys. Cool pain-related effects... journals.lww.com/pain/fulltex...
journals.lww.com
Reorganization of lateral habenula neuronal connectivity... : PAIN
ntra-LHb activity is altered during cognitive demand under neuropathic pain conditions. To address this gap, we implanted an optrode structure to record neuronal activity in adult male CD (rat strain ...
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GalhardoLab @galhardolab.bsky.social · 05/12/2024
Era-Net NEURON announced a new grant call on "Interdisciplinary Approaches to the Neueoscience of Pain". First selection phase will open on January '25 with a March deadline. Details will be announced soon... www.neuron-eranet.eu/joint-calls/...
neuron-eranet.eu
2025 “Interdisciplinary Approaches to the Neuroscience of Pain” - ERA-NET NEURON
Transnational Research Projects on Interdisciplinary Approaches to the Neuroscience of Pain | Official Launch 7th January 2025
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Mazen Kheirbek @mazenkheirbek.bsky.social · 04/12/2024
I am excited that my first Bluesky post is to share our new paper in @natureportfolio.bsky.social - "Understanding the neural code of stress to control anhedonia." With @fxia.bsky.social , @valeriafascianelli.bsky.social and @stefanofusi.bsky.social. www.nature.com/articles/s41...
nature.com
Understanding the neural code of stress to control anhedonia - Nature
Examination of the neural activity in the basolateral amygdala and ventral CA1 of mice during tasks or rest following exposure to social stress reveals signatures of resilience and susceptibility to s...
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GalhardoLab @galhardolab.bsky.social · 02/12/2024
The Era-Net NEURON has produced a series of 4 short videos on #PainScience 🧠 ✨ Leading neuroscientists discuss the science of pain and the evolution of research in this field. #PainScience #Neuroscience #Research www.youtube.com/watch?v=ubGH...
youtube.com
What About Pain: What is Pain
YouTube video by ERA-Net NEURON
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Jason Shepherd @jasonsynaptic.bsky.social · 21/11/2024
Tau filaments are packaged into extracellular vesicles derived from Alzheimer’s patient brains! Mounting evidence that EVs are important for tau transmission and pathology, as we show in our recent preprint. 🧠 🧪 www.nature.com/articles/s41...
nature.com
Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease - Nature Neuroscience
Using cryo-electron tomography (cryo-ET) and proteomics, this study identifies the tethering of pathological tau filaments within defined brain extracellular vesicles in Alzheimer’s disease, shining l...
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