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Gaurav Agarwal

@g-agarwal.bsky.social
112 followers 159 following 29 posts

Physician Scientist, haematologist in-training. Kennedy Scholar @ Harvard. Research Fellow in Sankaran Lab at Broad Institute & Boston Children's Hospital.

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Gaurav Agarwal @g-agarwal.bsky.social · 01/05/2026
Delighted to have been part of this study, out today in @cp-cell.bsky.social ! We identified a homeotic long non-coding RNA that modulates human HSCs and🩸cancer risk. Check it out! 👇
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Gaurav Agarwal @g-agarwal.bsky.social · 02/01/2026
What protects some people from leukemia? Thrilled to share my work at @bloodgenes.bsky.social lab, now published in @science.org. We identify an inherited genetic variant that protects stem cells from blood cancers by reducing risk of CHIP. t.co/ExgWIJQe6y 🧵👇(1/n)
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Gaurav Agarwal @g-agarwal.bsky.social · 02/01/2026
Thank you so much for highlighting our work, @erictopol.bsky.social !!
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Reposted by Gaurav Agarwal
Vijay G. Sankaran @bloodgenes.bsky.social · 26/12/2025
Enjoyed writing this commentary with @g-agarwal.bsky.social for @bloodjournal.bsky.social: ashpublications.org/blood/articl... Covers an exciting paper from Tapper and co: ashpublications.org/blood/articl... #mpnsm
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Reposted by Gaurav Agarwal
Vijay G. Sankaran @bloodgenes.bsky.social · 17/07/2025
Delighted to have our preprint led by @lvchosen1.bsky.social up: Genetic variation reveals a homeotic long noncoding RNA that modulates human hematopoietic stem cells biorxiv.org/content/10.1... 🧵 below ...
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Gaurav Agarwal @g-agarwal.bsky.social · 01/05/2025
Grateful to have our research illustrated so beautifully by @atjcagan.bsky.social ! 🙏 Check out our work below, in which we describe inherited genetic resilience that protects some individuals from blood cancers 👇 www.biorxiv.org/content/10.1...
biorxiv.org
Inherited resilience to clonal hematopoiesis by modifying stem cell RNA regulation
Somatic mutations that increase hematopoietic stem cell (HSC) fitness drive their expansion in clonal hematopoiesis (CH) and predispose to blood cancers. Although CH frequently occurs with aging, it r...
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Reposted by Gaurav Agarwal
Alexis Caulier @hemagene.bsky.social · 03/04/2025
Out today in @science.org! What if you could chart cells' regulatory programs at unprecedented resolution? In my work with Jorge Martin-Rufino from the @bloodgenes.bsky.social lab, we dissect the genome’s control circuits and find where key genetic variation hides bit.ly/3YhBMoO
bit.ly
Transcription factor networks disproportionately enrich for heritability of blood cell phenotypes
Most phenotype-associated genetic variants map to noncoding regulatory regions of the human genome, but their mechanisms remain elusive in most cases. We developed a highly efficient strategy, Perturb...
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Reposted by Gaurav Agarwal
Vijay G. Sankaran @bloodgenes.bsky.social · 27/03/2025
So proud of this incredible work from @g-agarwal.bsky.social from our group with help from many fantastic folks in our lab and inspiring collaborators, including @kharaslab.bsky.social, Alex Bick, @yashpershad.bsky.social, and many others! Please check out Gaurav's awesome 🧵👇👇
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Gaurav Agarwal @g-agarwal.bsky.social · 27/03/2025
What protects individuals from developing blood cancers? Thrilled to share my work in @bloodgenes.bsky.social lab, describing inherited resilience protecting blood stem cells from clonal hematopoiesis by modifying RNA regulation. 🧵👇 (1/n) www.biorxiv.org/content/10.1...
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