Catastrophic flash floods have swept through Nepal and communities along the Bhote Koshi river system, taking lives, destroying homes and critical infrastructure, and leaving hundreds of people unaccounted for. Floodwaters and debris have devastated remote communities across the Himalayan region as search-and-rescue efforts continue. Your donation to the Nepal Flood Relief Fund will provide urgent relief and long-term recovery support to communities impacted by this devastating disaster.

This dataset compiles experimentally validated splice leader (SL) sequences from diverse eukaryotic taxa, providing a comparative reference for studies on trans-splicing and RNA processing. Version 7 represents a major update from v3 (January 2025), nearly doubling the number of entries from 112 to 210 sequences (+98 entries, +87%).Taxonomic coverage has been significantly expanded to now include 11 phyla: Euglenozoa, Nematoda, Platyhelminthes, Cnidaria, Rotifera, Chordata, Alveolata, and four newly added phyla — Arthropoda (Copepoda), Chaetognatha (Sagittoidea), Cryptista (Cryptomonada), and Ctenophora (Tentaculata/Nuda). The largest expansions were in Nematoda, Cnidaria, and Chaetognatha.The dataset schema was restructured to improve phylogenetic resolution, replacing the single "Family" field with a two-level "Phylum / Subgroup" classification. A formal SL sequence naming convention was introduced, with 170 of 210 entries carrying standardized identifiers. Each entry includes the SL sequence (5' to 3'), sequence length, primary literature reference (DOI and PMID), and contributor information.

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Author summary A series of protein kinases act at the pinnacle of eukaryotic cells’ DNA damage response, organising and guiding repair. One such kinase is ATR, which recognises single-stranded DNA for...

Inter-Clade Recombinant Mpox Virus Detected in England in a Traveller Recently Returned from Asia Authors: Steven T. Pullan1, Isobel Everall1, Rebecca Doherty1, Lucy Crossman1, Emma Wise1, Hassan Ha...

Closing of programs that fought neglected diseases imperils drug donation and distribution efforts in 26 countries

Diplonemids are highly diverse and abundant marine plankton with significant ecological importance. However, little is known about their biology, even in the model diplonemid Paradiplonema papillatum ...

Version 2This table summarizes all splice leader sequences I, and other contributors, could find in the literature. The doi and PMID of the reference where the sequences were found serves as reference.This is table will be updated with new sequences if they are made available. Contact me if you want to add data to this, a new column will be added to give credit the person giving the data. This table was done on my free time and can not be associated to any funding.

This table summarizes all splice leader sequences I could find in the literature. The doi of the reference where the sequence was found serves as reference. This is table will be updated with new sequ...