Rhabdoid tumors are very aggressive rare pediatric cancers with poor survival affecting very young children. They are characterized by the bi-allelic loss of SMARCB1 or SMARCA4, which is suspected to ...

I recently re-read Richard Hofstadter's Anti-Intellectualism in American Life, and now every time a reactionary Silicon Valley billionaire opens his mouth, I think about it. So I wrote about it for Th...

Nature - This Review revisits tumour initiation and promotion in light of clonal diversity and the presence of cancer driver mutations in normal tissues, aiming to understand mechanisms that enable...

Sex bias and association with smoking history identified in the landscape of driver mutations and clonal expansions in normal human bladder tissue may explain the higher bladder cancer risk in men and smokers.

GENEVA – Israel has committed genocide against Palestinians in the Gaza Strip, the UN Independent International Commission of Inquiry on the Occupied Palestinian Territory, including East Jerusalem, a...

Abstract. Identifying the genes capable of driving tumorigenesis in different tissues is one of the central goals of cancer genomics. Computational methods

The corrosive damage cause by forcing people to defend their own lives by debating ideas that have already been defeated.

Dark isn't the opposite of light, it's the absence of light.

5k words, 23 minutes reading time

an AI researcher going back to school for immunology

From the highly eclectic blog of Mark Dominus

Clonal hematopoiesis is the expansion of a genetically related population of hematopoietic stem and progenitor cells that disproportionately contribute to blood-cell production.1 Clonal hematopoies...

Nature Genetics - Whole-genome sequencing and mutational signature analysis of 265 head and neck cancer samples collected from eight different countries provide insight into the vital contribution...

Tired of spending countless hours on peer reviews? An AI-assisted workflow could help.

Mountaineers now scaling more peaks for first global study of nanoplastics, which can enter lungs and bloodstream

AbstractSummary. Advances in high-throughput DNA sequencing technologies and decreasing costs have fueled the identification of small genetic variants (suc