Reposted by Florian KämpfMarine Biological Laboratory @mblscience.bsky.social · 30/06/2026Join us on July 3 to hear Lauren O’Connell discuss how young brains create social behavior and methods of communication to meet needs such as hunger. Free and open to the public for in-person and virtual attendance. 🔗 More info here: go.mbl.edu/fel 034
Reposted by Florian KämpfSimone (she/her) @simonerencken.bsky.social · 31/05/2026I’m happy to share that our paper about the Sepia officinalis genome is out in eLife!🧬 We compared the assemblies of two individuals that had a different predicted number of chromosomes, and found highly repetitive regions that likely prevented a complete assembly. elifesciences.org/articles/107... 02210
Reposted by Florian KämpfBahl Lab @bahllab.bsky.social · 05/03/2026New paper out: www.nature.com/articles/s41... 🥳 Congratulations to our PhD student Katja for her inspiring work just published in Nature Communications on how the larval zebrafish brain processes multiple visual features. Check out a short summary of the work here: tinyurl.com/yzv4ct9k 04614
Reposted by Florian KämpfJohn Tuthill @tuthill.bsky.social · 24/12/20250.00003 foot tall xmas tree from a Drosophila flight steering muscle 🎄 image by @anne-sustar.bsky.social 657786
Reposted by Florian KämpfNnedi Okorafor, PhD @nnedi.bsky.social · 21/11/2025Earlier today, I was notified that someone was at my door. This is who it was: 809453437144
Reposted by Florian KämpfMRC Laboratory of Molecular Biology @mrclmb.ac.uk · 24/10/2025Congratulations to the 2025 recipients of the Perutz Student Prize and the Joan Steitz Postdoc Prize: Claudia De Miguel, @lucaschwarz.bsky.social, Tom Dendooven, Sofia Lövestam, Katerina Naydenva & Tomke Stürner. Find out why they won here: www2.mrc-lmb.cam.ac.uk/lmb-prizes-2... #LMBNews 👏 0165
Reposted by Florian KämpfPhilip Hubbard @philiphubbard.bsky.social · 08/10/2025Some fly neurons are “dimorphic”, existing in both males and females but connecting to different neighboring neurons. Neighbors may be “isomorphic”, the same in both male and female; or sex specific; or dimorphic themselves. Here's an example, the type AOTU012, present in left and right instances. 0175
Reposted by Florian Kämpfstuartberg.bsky.social @stuartberg.bsky.social · 15/10/2025We provide the most detailed picture yet of the result of sexually dimorphic development of the nervous system. The dataset should be a game-changer for researchers exploring behaviour, circuits & brain wiring! Check out male-cns.janelia.org. Huge thanks to our amazing team of co-authors! 10/10 112
Reposted by Florian KämpfBella @beckett14.bsky.social · 15/10/2025Statistical analysis of connectivity within the central brain shows that around 6.5% of synaptic connections in the male and 1.3% of connections in the female are dimorphic. In the male, sex-specific circuit elements form highly interconnected clusters with similar connectivity. 9/10 112
Reposted by Florian KämpfMarta Costa @mmcosta.bsky.social · 15/10/2025We explore #dimorphism across sensory modalities (visual and auditory systems, gustation and olfaction) and find, for example, a putative functional “love spot” involving male-specific neurons. 8/10 111
Reposted by Florian KämpfBella @beckett14.bsky.social · 15/10/2025Comparing the EM neurons to light microscopy datasets of fruitless and doublesex expression, we annotated the putative expression pattern of these genes for both the male and female connectomes. 7/10 113
Reposted by Florian KämpfMarta Costa @mmcosta.bsky.social · 15/10/2025We cross-matched neurons and identified over 7k isomorphic, 114 sexually dimorphic, 262 male- and 69 female-specific cell types. In total, these neurons make up 4.8% and 2.4% of the male and female brain, respectively. 6/10 133
Reposted by Florian KämpfGreg Jefferis @jefferis.bsky.social · 15/10/2025As the first (and so far, only) male brain, we compared this connectome to the previously published #FlyWire #FAFB female dataset to investigate the structural differences across male and female brain connectomes. 5/10 152
Reposted by Florian KämpfBella @beckett14.bsky.social · 15/10/2025Using these annotations we ran end-to-end analyses going from sensory inputs all the way to motor outputs. This showed, for instance, that ascending and descending neurons are not passive relays but likely perform complex transformations of information flowing between brain and nerve cord. 4/10 184
Reposted by Florian KämpfMarta Costa @mmcosta.bsky.social · 15/10/2025This is the first completely proofread connectome of a nervous system (brain + nerve cord) for an adult animal with complex behaviour: 167k neurons with rich annotations (classes, cell types, developmental lineages, …) to help explore the dataset and 125M synaptic connections between them. 3/10 182
Reposted by Florian Kämpfstuartberg.bsky.social @stuartberg.bsky.social · 15/10/2025A hugely successful collaboration between @janelia-flyem.bsky.social @camzoology.bsky.social @mrclmb.bsky.social with @beckett14.bsky.social @mmcosta.bsky.social Philipp Schlegel (not on Bluesky) and many others. Major funding from @wellcometrust.bsky.social and @hhmijanelia.bsky.social. 2/10 151
Reposted by Florian KämpfGreg Jefferis @jefferis.bsky.social · 15/10/2025Excited to share our new #biorxivpreprint: “Sexual dimorphism in the complete connectome of the Drosophila male central nervous system” www.biorxiv.org/content/10.1... We describe the #connectomics reconstruction and analysis of an entire adult #maleCNS #drosophila central nervous system. 1/10 112868
Reposted by Florian KämpfCamBRAIN | The Cambridge Neuroscience Society @cambraincns.bsky.social · 07/10/2025WELCOME BACK! Join us for an aptly themed Let's Get Social Neurotalks next week to kick off the new year. Social robots, and how flies use touch to make social decisions with Alva Markelius and @flofightscience.bsky.social 🗓️Tues 14 October 🕓7pm-9pm 🗺️ Cambridge Tap 001
Reposted by Florian KämpfGreg Jefferis @jefferis.bsky.social · 05/10/2025Exciting news for #drosophila #connectomics and #neuroscience enthusiasts: the Drosophila male central nervous system connectome is now live for exploration. Find out more at the landing page hosted by our Janelia FlyEM collaborators www.janelia.org/project-team....janelia.orgMale CNS ConnectomeA team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ... 214669
Reposted by Florian KämpfJanelia Research Campus @hhmijanelia.bsky.social · 06/10/2025🪰 A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the millions of connections between them. 🔗 hhmi.news/4o3EJnk 14620
Reposted by Florian KämpfJanelia FlyEM @janelia-flyem.bsky.social · 05/10/2025We're very proud to be releasing the complete male fly CNS connectome! It's the product of a huge team effort here at Janelia in partnership with the Cambridge Fly Connectomics group (@jefferis.bsky.social and colleagues), plus invaluable collaborators. More soon... www.janelia.org/project-team...janelia.orgMale CNS ConnectomeA team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ... 26931
Reposted by Florian KämpfLMB-EPFL Graduate Life Sciences Symposium 2026 @lmbphdsymposium.bsky.social · 21/05/2025Save the Date 📍 Where: MRC-LMB, Cambridge or Online (Zoom) 🗓️ When: 10th and 11th of July 🧪 Themes: Cell Biology, Structural Biology, Immunology, Nucleic Acids and Neuroscience. 🤝 In collaboration with students at Institut Pasteur 584
Reposted by Florian KämpfKatrin Vogt @katrinvogt.bsky.social · 24/03/2025The first paper from the lab is out on biorxiv - enjoy reading! Social context and interactions influence our behavioral decisions - the same is true for the little fly larva! 35118
Florian Kämpf @flofightscience.bsky.social · 17/03/2025Our new paper on the circuit implementation of evidence integration in larval zebrafish is now on bioRxiv! 170
Reposted by Florian KämpfbioRxiv Neuroscience @biorxiv-neursci.bsky.social · 16/03/2025Correlative light and electron microscopy reveals the fine circuit structure underlying evidence accumulation in larval zebrafish www.biorxiv.org/content/10.1101/202… 0103
Reposted by Florian KämpfBahl Lab @bahllab.bsky.social · 17/03/2025Such biophysically realistic network modeling provides the foundation for precise hypothesis-driven circuit manipulations, electrophysiology, and transcriptomic analysis in the future. So stay tuned😄(10/10) 041
Reposted by Florian KämpfBahl Lab @bahllab.bsky.social · 17/03/2025Our anterior hindbrain circuit model, based on ground-truth connectivity, reproduces experimentally observed neural dynamics and predicts new mechanisms for flexible decision-making. (9/10) 031
Reposted by Florian KämpfBahl Lab @bahllab.bsky.social · 17/03/2025Using 2P photo-activations and a ML classifier, we assigned functional labels to neurons based solely on morphology, enhancing our EM dataset. Our classifier also provides a basis to assign functional labels to other cell library resources for which calcium imaging had not been performed. (8/10) 021
Reposted by Florian KämpfBahl Lab @bahllab.bsky.social · 17/03/2025After many months of intense tracing and synapse annotation, the result is a detailed connectome of functionally identified cells within the anterior hindbrain. (7/10) 031
Reposted by Florian KämpfBahl Lab @bahllab.bsky.social · 17/03/2025We performed 2P calcium imaging to identify functional cell types related to this integration process. We then performed EM on the same preparation and mapped the two datasets together with cellular precision. Zetta AI has been instrumental in processing and segmenting the EM dataset. (6/10) 031
Reposted by Florian KämpfBahl Lab @bahllab.bsky.social · 17/03/2025We use larval zebrafish, challenged with the classical random dot motion paradigm in which they need to accumulate motion evidence during sensory-motor decision-making. (image credit: Mariela Petkova) (5/10) 021
Reposted by Florian KämpfBahl Lab @bahllab.bsky.social · 17/03/2025We are thankful to all the many many many other students and postdocs who helped with the experiments, imaging analysis, tracing, and database curation. (4/10) 011
Reposted by Florian KämpfBahl Lab @bahllab.bsky.social · 17/03/2025The work has been a very productive collaboration between our lab, the Lichtman and Engert labs at Harvard University (connectomics), and the Baum lab at Zuse-Institut Berlin (Computer Science). (3/10) 011
Reposted by Florian KämpfBahl Lab @bahllab.bsky.social · 17/03/2025In a heroic effort, the lead authors @boulangerweill.bsky.social and @flofightscience.bsky.social combined light and electron microscopy to address a long-standing question in neuroscience: What are the neural circuit mechanisms that allow animals to accumulate sensory evidence? (2/10) 031
Reposted by Florian KämpfBahl Lab @bahllab.bsky.social · 17/03/2025We are proud to present our new preprint “Correlative light and electron microscopy reveals the fine circuit structure underlying evidence accumulation in larval zebrafish”, just posted on bioRxiv (www.biorxiv.org/content/10.1...). (1/10)biorxiv.orgCorrelative light and electron microscopy reveals the fine circuit structure underlying evidence accumulation in larval zebrafishAccumulating information is a critical component of most circuit computations in the brain across species, yet its precise implementation at the synaptic level remains poorly understood. Dissecting su... 115121
Reposted by Florian KämpfIain Couzin @icouzin.bsky.social · 27/02/2025Virtual reality rewrites the rules of the swarm. www.science.org/doi/10.1126/... We find that classical models of collective behavior fail to account for collective motion. www.science.org/doi/10.1126/...science.orgThe behavioral mechanisms governing collective motion in swarming locustsCollective motion, which is ubiquitous in nature, has traditionally been explained by “self-propelled particle” models from theoretical physics. Here we show, through field, lab, and virtual reality e... 06926
Reposted by Florian KämpfYannick Günzel @yguenzel.bsky.social · 28/02/2025🚨🦗 Virtual reality experiments revealed that a minimal cognitive framework - and not explicit neighbor alignment - drives collective motion, rewriting the rules of swarm behavior! #VR #Swarm #Science #Locust Don’t miss it; check out the paper here: www.science.org/doi/10.1126/...science.orgThe behavioral mechanisms governing collective motion in swarming locustsCollective motion, which is ubiquitous in nature, has traditionally been explained by “self-propelled particle” models from theoretical physics. Here we show, through field, lab, and virtual reality e... 031
Reposted by Florian KämpfAndrew D Wilson @adw.bsky.social · 13/01/2025I have made this slide for a talk and I'm not sure it's staying in but I do think it's quite good :) 2352
Reposted by Florian KämpfMRC Laboratory of Molecular Biology @mrclmb.ac.uk · 06/01/2025Reminder: Outstanding opportunity to open your group in the LMB’s Neurobiology Division as part of our Molecular Connectomics Initiative! You will be supported by core funding, excellent facilities and a lively international community of researchers. Apply by 19 Jan www.nature.com/naturecareer... 02019
Reposted by Florian KämpfScience Magazine @science.org · 03/01/2025A new study finds ants best humans at tests of collective intelligence. Learn more: scim.ag/4h2K0ID 26506166
Reposted by Florian KämpfPhoebe Reynolds @pheereynolds.bsky.social · 11/12/2024I’m over the moon to have won the @britishneuro.bsky.social award for Public Engagement 2024 🥳✨🧠 Massive thanks to the panel! This is such an exciting recognition of public engagement work in neuroscience! @kingscollegelondon.bsky.social @devneuro.bsky.social 2315
Florian Kämpf @flofightscience.bsky.social · 29/11/2024This is from when I was conducting field research at Lake Tanganyika in Zambia, studying the social evolution of shell-dwelling cichlids 🐟🐚 It was an incredible experience, but it didn’t quite satisfy the data monster within me 💾🧟♂️ 010
Florian Kämpf @flofightscience.bsky.social · 28/11/2024Post a picture of yourself from a different era. 262
Florian Kämpf @flofightscience.bsky.social · 19/11/2024This thread is a wonderful eternal reading list 030
Florian Kämpf @flofightscience.bsky.social · 15/11/2024It's been three days since I switched from X/Twitter to BlueSky, and I'm coming to the conclusion that I still don't know how to create original posts. 😭 260
Florian Kämpf @flofightscience.bsky.social · 14/11/2024@handle.invalid should be @mehaj.bsky.social 000
Florian Kämpf @flofightscience.bsky.social · 14/11/2024Could you add @handle.invalid and @kircheaufdemberg.bsky.social ? 100