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Shelly Flagel

@flagel-lab.bsky.social
1.9K followers 439 following 83 posts

Behavioral neuroscientist (motivation, inhibitory control, individual variability) --> flagellab.com Professor of #Neuroscience & #Psychiatry, University of Michigan #GoBlue Here for science, community, & to promote things I care about.

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Shelly Flagel @flagel-lab.bsky.social · 05/10/2026
Deadline extended to November 15th! 👇
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Shelly Flagel @flagel-lab.bsky.social · 05/10/2026
👏👏👏
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Shelly Flagel @flagel-lab.bsky.social · 18/09/2026
Have fun and take care of the umich contingent that is there! Sad to miss it.
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European Behavioural Pharmacology Society @eurbehavpharm.bsky.social · 09/09/2026
We are seeking papers for two special issues that the EBPS is guest-editing in our partner journal @psychopharmacology.bsky.social. We are seeking papers for both special issues.
static.klipy.com
Tainámüller Looking Through Files
ALT: Tainámüller Looking Through Files
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Shelly Flagel @flagel-lab.bsky.social · 17/08/2026
Not sure how I missed the original post. Very exciting! Looking forward to digging in to the Nature Comms paper. Congrats!
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Shelly Flagel @flagel-lab.bsky.social · 10/08/2026
Do you work in #addictionresearch? Interested in #machinelearning or #AI to better understand #addiction? Submit a manuscript to #Psychopharmacology Special Issue by Oct. 1. Big data, artificial intelligence, and machine learning in addiction research | Link share.google/GXfeNBPdZ95x...
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Shelly Flagel @flagel-lab.bsky.social · 23/03/2026
Our article examining the effects of chronic #GLP-1 receptor agonist (#semaglutide #ozempic) treatment on the incentive motivational value of a small #food reward and the cue that predicts it is now out in Psychopharmacology. Open access article 👇 link.springer.com/10.1007/s002...
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European Behavioural Pharmacology Society @eurbehavpharm.bsky.social · 06/02/2026
Call for papers for a Special Issue on Big Data, AI and Machine Learning in Addiction research, guest edited by @flagel-lab.bsky.social and @gavanm.bsky.social in @psychopharmacology.bsky.social link.springer.com/collections/...
link.springer.com
Big data, artificial intelligence, and machine learning in addiction research
Recent advances in big data analytics, artificial intelligence, and machine learning are transforming research by enabling the integration and interrogation ...
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Shelly Flagel @flagel-lab.bsky.social · 13/12/2025
That is what I usually do too, but it wasn't a good strategy while pipetting. 😏
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Shelly Flagel @flagel-lab.bsky.social · 13/12/2025
I was excited to get into the lab today to help out with an experiment...until I realized I now need readers to make out the labels on eppendorfs and pipettes. #oldPIproblems 🔬🧪🔎
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Shelly Flagel @flagel-lab.bsky.social · 10/12/2025
In this case, I think the difference is our treatment paradigm. We are using a chronic GLP-1 receptor agonist treatment regimen (similar to that humans experience), whereas most of what we know from the preclinical literature to-date is based on acute treatment.
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Shelly Flagel @flagel-lab.bsky.social · 10/12/2025
Yes, there is a lot of literature to support a dampening of motivation for food- and drug-rewards, but the big difference here is that we used a chronic treatment regimen (similar to that humans experience); whereas most preclinical studies I am familiar with use acute treatment regimens.
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Shelly Flagel @flagel-lab.bsky.social · 10/12/2025
Grateful for the outstanding efforts of THE TEAM, led by Steve Chang, and generous support from the University of Michigan Research Scouts Program (OORRS033123) and NIH (T32DA060142: Christopher Turner, T32DA007281: Daniela Pereira, R25GM086262: Natalia Morales Pagán).
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Shelly Flagel @flagel-lab.bsky.social · 10/12/2025
This marks an important first step toward understanding the psychological and neurobiological impacts of chronic GLP-1 receptor agonist treatment. We have a lot more work to do! 4/
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Shelly Flagel @flagel-lab.bsky.social · 10/12/2025
While these findings may at first seem counterintuitive compared to reports from human subjects, they suggest that these drugs amplify the reinforcing effects of small rewards and associated cues, leading to quicker satiety. 3/
media.tenor.com
a cartoon of garfield with the words how i feel right now above him
ALT: a cartoon of garfield with the words how i feel right now above him
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Shelly Flagel @flagel-lab.bsky.social · 10/12/2025
We set out to explore how GLP-1 receptor agonists influence incentive motivational processes. Surprisingly, chronic semaglutide treatment increased motivation for food and associated cues under restricted access, but decreased overall consumption when food was freely available. 2/
media.tenor.com
a cartoon of homer simpson eating a hamburger with the words trendizisst at the bottom
ALT: a cartoon of homer simpson eating a hamburger with the words trendizisst at the bottom
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Shelly Flagel @flagel-lab.bsky.social · 10/12/2025
Excited to share our new GLP-1 receptor agonist study! Chronic semaglutide potentiates motivation for small food rewards and associated cues, but reduces intake when food is freely available—surprising twist! #GLP-1, #behavior #neuroscience #pharmacology 1/ 🔗 www.biorxiv.org/cgi/content/...
biorxiv.org
Chronic semaglutide treatment enhances the incentive motivational value of a small food reward and associated cue in male and female rats
Rationale: Glucagon-like peptide-1 (GLP-1) receptor agonists, such as semaglutide, are increasingly utilized in clinical practice due to their efficacy in promoting sustained weight loss following chr...
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Angeline J. Dukes, PhD @heydrdukes.bsky.social · 18/11/2025
If you didn’t get a chance to purchase the exclusive 5-year #BlackInNeuro pin last night, I have more with me today! ✨ We’re asking for $15 donations to support BIN programming ❤️ blackinneuro.com/donate Allies are welcome to purchase pins as well 🙌🏾 #SfN25
A hand holding a Black In Neuro 5 year pin with a pile of them on a table in the background. The pin is a gorgeous gold laurel wreath with the original Black In Neuro logo on top and the big gold glittery 5 on the bottomA hand holding a Black In Neuro 5 year pin against a white linen background. The pin is a gorgeous gold laurel wreath with the original Black In Neuro logo on top and the big gold glittery 5 on the bottom
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Shelly Flagel @flagel-lab.bsky.social · 17/11/2025
We ate well last night (in a tent, indoors, with s'mores for dessert), and are energized to talk science today at #SfN2025. Come visit our posters: AA14 this morning Y11, GG13, HH11 this afternoon
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Shelly Flagel @flagel-lab.bsky.social · 16/11/2025
Go support all the amazing early career scientists who will be presenting their posters tonight from 6:45 - 8:45 at #SfN2025. This includes Flagel Lab graduate student, Princess Felix, who received a SfN Trainee Professional Development Award. 👏👏👏
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Shelly Flagel @flagel-lab.bsky.social · 11/11/2025
We're looking forward to telling you what we've been up to at #sfn25. Flagel Lab posters are all on Monday. Come say hi and speak to these amazing trainees about their research!
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Shelly Flagel @flagel-lab.bsky.social · 27/10/2025
Our last virtual open house for the season for our University of Michigan #neuroscience #graduateprogram is Wednesday October 29th, from 7-8:30 PM EST. If you would like to join us, please register by 9 AM Wednesday by scanning the QR code below. 👇
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Shelly Flagel @flagel-lab.bsky.social · 14/10/2025
Our first virtual open house for the University of Michigan #neuroscience #graduateprogram is tomorrow, October 15th, from 7-8:30 PM EST. If you would like to join us, please register by 9 AM tomorrow using this link: forms.gle/N6LjUrfrr6qL... or scan the QR code below. 👇
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Shelly Flagel @flagel-lab.bsky.social · 08/10/2025
It was a great day @westernu.ca, and such an honor to be selected by students for the Treva Glazebrook Lecture. Thank you, Kendra Loedige, for being a wonderful host. Great to see you and catch up, @drjkhokhar.bsky.social - thanks for teaching me about academia in Canada. 🤩🇨🇦
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Shelly Flagel @flagel-lab.bsky.social · 03/10/2025
Interested in #graduateprograms in #neuroscience? Come learn about our Neuroscience Graduate Program at the University of Michigan. We are offering virtual and in person opportunities to do so in October and November. #SfN2025 #SACNAS #ABRCMS See flyer below and #GoBlue! 👇
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Tallie Z Baram @talliezee.bsky.social · 25/09/2025
Published! to NAIL human paraventricular thalamus, we imaged & aligned postmortem human thalamus labeled c calretinin. Finally a gold standard allowing mouse, rat human comparisons onlinelibrary.wiley.com/doi/10.1002/... @ted-satterthwaite.bsky.social @flagel-lab.bsky.social @mikeyassa.bsky.social l
onlinelibrary.wiley.com
A Combined Neuroanatomy, Ex Vivo Imaging, and Immunohistochemistry Defined MRI Mask for the Human Paraventricular Nucleus of the Thalamus
Existing definitions of the human paraventricular nucleus of the thalamus (PVT) differ between histological and MRI atlases; this study addresses this conflict by leveraging MRI and histology in the ...
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Shelly Flagel @flagel-lab.bsky.social · 24/09/2025
Always fun to chat with Gill Eapen @ Scientific Sense, and made even more fun with @jbeehner.bsky.social. Learn a bit more about our investigations of sign-/goal-tracking in wild white-faced capuchins, and other related topics. 👇 Audio: podcasts.apple.com/us/podcast/p... Video: youtu.be/NUPI0xNj5U8
podcasts.apple.com
Prof. Shelly Flagel and Prof. Jacinta Beehner of the University of Michigan on goal/sign tracking
Podcast Episode · Scientific Sense ® · 09/21/2025 · 57m
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Shelly Flagel @flagel-lab.bsky.social · 20/09/2025
It's been fun. Thanks for hosting us, beautiful Almería, and thanks to everyone at #EBPS2025 for making it a fantastic meeting. Hoping everyone has safe and easy travels. 🤞 See you at #EBPS2027 in Cork!
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Carmen Sandi @carmensandi10.bsky.social · 20/09/2025
A brilliant keynote today by @jfcryan.bsky.social at the EBPS meeting on how the gut shapes behavior, including striking causal evidence for microbiome’s role in social behaviors. A masterclass of body-brain complexity! & with an impressive depth of data and the right dose of humor!
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European Behavioural Pharmacology Society @eurbehavpharm.bsky.social · 19/09/2025
Presidents dinner at #EBPS2025. So great to connect with EC members featuring 5 EBPS presidents
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Shelly Flagel @flagel-lab.bsky.social · 17/09/2025
Registration booth is open! Get there early to avoid lines and get your awesome swag! ##EBPS2025 @eurbehavpharm.bsky.social
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Shelly Flagel @flagel-lab.bsky.social · 16/09/2025
#EBPS2025 we'll be ready for you tomorrow!
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Shelly Flagel @flagel-lab.bsky.social · 14/09/2025
Anyone else EXCITED about #EBPS2025? 🎉 Safe travels to everyone coming from around the globe to gather with us in Almeria! 🌎✈️ We still have work to do, but I am proud of our geographic representation at this small meeting. Thank you @connorhaggarty.bsky.social and Margarita Moreno for the image!
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Casey terHorst @ecoevolab.bsky.social · 08/09/2025
The GRFP lives!! (due end of October) www.nsf.gov/funding/oppo...
nsf.gov
NSF Graduate Research Fellowship Program (GRFP)
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Shelly Flagel @flagel-lab.bsky.social · 05/09/2025
Did my best to stay positive for our "2025–2026 State of the Lab" address. Here’s to keeping the science (and this awesome crew) afloat.
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Shelly Flagel @flagel-lab.bsky.social · 05/09/2025
#FluoresenceFriday capturing the beauty and complexity of midline thalamic nuclei - projections to/from & c-fos (teal). Maybe there is more to the midline thalamus than the PVT? 😉 Thanks to postdoc, Stephanie Desrochers, and undergraduate student, Lea Hsu, for capturing! 🤩
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Neuropsychopharmacology @npp-journal.bsky.social · 05/08/2025
#ThisWeekInNPP Drs. Beehner (@jbeehner.bsky.social) & Flagel (@flagel-lab.bsky.social) of UMichigan call for more experimental & mechanistic field research to provide causal insights & complement lab studies, thereby ⬆️ the translational value of behavioral neuroscience research 🐭🐵🧒
nature.com
Field experimentation enhances translation for behavioral neuroscience - Neuropsychopharmacology
Neuropsychopharmacology - Field experimentation enhances translation for behavioral neuroscience
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Shelly Flagel @flagel-lab.bsky.social · 05/08/2025
Thanks for the hlighlight @thetransmitter.bsky.social! @jbeehner.bsky.social and I are very excited to further explore some of the ideas put forth in this article.
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Shelly Flagel @flagel-lab.bsky.social · 25/07/2025
Excited to have this little @npp-journal.bsky.social "hot topics" article out with my dear friend and collaborator @jbeehner.bsky.social. Even more excited for the opportunity to jump into field research and explore some of these ideas. www.nature.com/articles/s41...
nature.com
Field experimentation enhances translation for behavioral neuroscience - Neuropsychopharmacology
Neuropsychopharmacology - Field experimentation enhances translation for behavioral neuroscience
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The Transmitter @thetransmitter.bsky.social · 16/06/2025
Neuroscience research and training has taken a $323 million hit in the form of grants rescinded by the U.S. NIH, according to an analysis by @thetransmitter.bsky.social. By @claudia-lopez.bsky.social #neuroskyence www.thetransmitter.org/funding/nih-...
thetransmitter.org
NIH cuts quash $323 million for neuroscience research and training
“I am frightened for the state of the future of our field if this isn't reversed rapidly,” says Joshua Gordon, professor of psychiatry at Columbia University and former director of the National…
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Drug Monkey @drugmonkey.bsky.social · 04/06/2025
When NIH fixes exclude you drugmonkey.wordpress.com/2025/06/04/w...
drugmonkey.wordpress.com
When NIH fixes exclude you
In the midst of all the chaos at NIH of late, there have been two small glimmers of relief. First was the extension of Early Stage Investigator eligibility. The NOT-OD-25-114 [NIH] hereby grants th…
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Shelly Flagel @flagel-lab.bsky.social · 04/06/2025
Thank you @sfn.org for providing some normalcy during these trying times. 😏 #SFN2025
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Shelly Flagel @flagel-lab.bsky.social · 30/05/2025
😄 Nothing special, an old Samsung Galaxy. Their beauty was easy to capture. 😍
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Shelly Flagel @flagel-lab.bsky.social · 30/05/2025
Friday afternoon #mentalhealth #wellness break at the #annarbor #peonygarden.
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Shelly Flagel @flagel-lab.bsky.social · 21/05/2025
It was hard for me to enjoy the "moment" as a mentor yesterday, when the funding mechanisms for each of these two individuals (+1 more in my lab) have been terminated. I will continue to fight the good fight, but we all have to do this together - for the next generation and for science. 2/2
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Shelly Flagel @flagel-lab.bsky.social · 21/05/2025
I am so proud of Natalia Morales Pagan, a #postbac student in my lab, for showcasing all of her growth and hard work this past year in her final presentation yesterday; and of Brianna Ramos, a #neuroscience #graduatestudent in my lab, for her excellent 4th year presentation. 1/2
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Drug Monkey @drugmonkey.bsky.social · 06/05/2025
It's all very well to be brave when you face fewer consequences than others drugmonkey.wordpress.com/2025/05/06/i...
drugmonkey.wordpress.com
It’s all very well to be brave when you face fewer consequences than others
It’s only Tuesday and I am already having a bit of a week with respect to local responses to the assaults on NIH and on Universities. In the beginning I was very critical of institutional beh…
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Shelly Flagel @flagel-lab.bsky.social · 26/04/2025
It actually feels like 10 years to me. 😏
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Shelly Flagel @flagel-lab.bsky.social · 26/04/2025
Better than a dopamine ring? 😉 These might be a new tradition.
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Shelly Flagel @flagel-lab.bsky.social · 26/04/2025
Flagel Lab end-of-semester and early graduation celebration. Very grateful for this crew. Bittersweet to send two undergrads, Vrinda Varada and Zoya Bashir, off to their next Chapter. #forevergoblue
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