iiinova — where your digital self keeps evolving

Fil Bednar @filbednar.bsky.social · 19/10/2025

Some tremendous photography on this site showing the everyday beauty around us. We make the world around us, so I will try to contribute in my own little way… This is not the Carribean, Fiji, or the Med. This is southwest Michigan!

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kasitc.bsky.social @kasitc.bsky.social · 18/08/2025

Activity of most genes is controlled by multiple enhancers, but is there activation coordinated? We leveraged Nanopore to identify a specific set of elements that are simultaneously accessible on the same DNA molecules and are coordinated in their activation. www.biorxiv.org/content/10.1...

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academicsurgery.bsky.social @academicsurgery.bsky.social · 01/09/2025

🚨 Last week to apply for AAS Student Travel Awards! Both awards provide travel funding to attend the AAS Annual Meeting, connect with leaders in the field, and advance your academic surgery career. 📅 Deadline: September 5, 2025 Don’t miss your chance! Apply today: www.aasurg.org/awards/stude...

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Julie Hallet, MD MSc @halletjulie.bsky.social · 14/02/2025

What to do with carcinoid crisis? 🦓 A frequent concern for patients with #NETs having surgery We put together an international 🌎🌍🌏 multidisciplinary expert consensus statement 📢 Now open for feedback! Sign-up here 🔗 surveymonkey.com/r/periopcarc... 📆 Open until March 3rd!

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Cat Hicks @grimalkina.bsky.social · 08/02/2025

Having funded teams/contracts that required six figure+ funds a few times now, these numbers SOUND really huge in isolation to normal folks but they're not! Don't make floating numbers! I like to say things like this: "A cancer lab is basically a small business, with many jobs created by each grant"

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Fil Bednar @filbednar.bsky.social · 09/01/2025

Hot take (or lukewarm…): with “AI” models predicting all sorts of genome/chromatin phenomena, it’s important to remember that these are still models! Experimental validation remains hard and is still key! #GeneRegulation #GeneSky #Chromatin

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Richard Sever @richardsever.bsky.social · 08/01/2025

Yes it's important people understand a preprint hasn't been peer-reviewed. BUT it's also important to understand that what "peer-reviewed" means varies considerably, in some cases signifying nothing... www.science.org/content/arti...

science.org

Preprints often make news. Many people don’t know what they are

The public needs context about unreviewed manuscripts, survey suggests

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Metastasis Research Society @metastasisresearch.bsky.social · 31/12/2024

1/Happy new year from the Metastasis Research Society! As we close out 2024, here are some additional studies that have shaped our understanding of metastasis biology this year. 🧵...

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Stephen Heard @stephenbheard.bsky.social · 23/12/2024

For anyone reading blogs over the holiday: Despite claims that the lecture is (or should be) dead, we'll still be doing it for the foreseeable future. So, we might as well do it well. Some tips based on my career of gradually sucking less: scientistseessquirre...

scientistseessquirrel.wordpress.com

Lightening up the lecture

I write occasional commissioned pieces for Jobs.ac.uk, and today I’m mostly pointing you to my latest one over there. The lecture gets a bad rap. It’s pretty easy to find essays deploring the whole…

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Jeremy Berg @jeremymberg.bsky.social · 22/12/2024

Bluetorial: Mentors III The tall chemist from Nantucket My PhD thesis advisor was a great synthetic chemist and a true scholar. He gave me freedom to pursue my dissertation research. Lots of chemistry today. And a surprising and somewhat distressing ending.

media.tenor.com

a cartoon says hey everybody an old man 's talking while bart simpson looks on

ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on

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CC @cckirby.bsky.social · 19/12/2024

only just learned that using "from:me" in the search bar along with whatever phrases you're looking for is the way to look for posts on here that were made by you and I feel like I'm not the only one who didn't realize that and would probably be glad to know such a function exists

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Fil Bednar @filbednar.bsky.social · 12/12/2024

All sorts of winning happening this morning in my office! Thanks to the unnamed journal sending a friendly SECOND notice for a review of a manuscript, which isn’t due until a week from today! Gee, I almost forgot after the first one… (Narrator: he didn’t forget…)

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Fil Bednar @filbednar.bsky.social · 12/12/2024

Wanna talk about why patients and doctors are angry and tired of health insurance companies? I just spent 15 minutes of my day across two phone calls with two humans and one robot to appeal a denial of a CT scan for a cancer patient. The CT is a standard of care in their case. 1/2

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Terry McGlynn @hormiga.bsky.social · 09/12/2024

One thing that all professors have in common in that we weren't trained for our jobs. Now that I've been doing this for a few decades, I'm starting an occasional series called Professor School. It's not advice, just bunch of ideas and information to make things easier. 🧪

open.substack.com

Professor School: Writing recommendation letters

Because we were never trained for this job

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Fil Bednar @filbednar.bsky.social · 04/12/2024

Cool analysis of large public scRNA-seq datasets and how stringent our approaches should be to scRNA-seq quality control. The DropletQC paper from 2021 may not currently have as many citations as expected, but the idea is sound and good ideas stand the test of time. This work supports this notion!

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Anna Obenauf @obenaufa.bsky.social · 27/11/2024

1/23 Big news for the #ObenaufLab! So excited to finally share our new study providing another puzzle piece, why immunotherapy fails in many tumors, now out in @Nature 🧵👇 www.nature.com/articles/s41...

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Nature Reviews Immunology @natrevimmunol.nature.com · 26/11/2024

The danger theory of immunity strikes back... rdcu.be/d1uQN

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Jamie Hackett @jamiehackett.bsky.social · 28/11/2024

Starter packs are fab, but skew towards established folks Cue intros into all the amazing people in our lab… give them a follow 🚶 First up Marzia Munafo. Leading a spectacular oocyte epigenomics project (watch this space 👀) and science illustrator extraordinaire. Check out the beautiful works 👇👇

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Dorien Pastoors @dpastoors.bsky.social · 27/11/2024

@sproullab.bsky.social has made chromatin starter packs!

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Nogales Lab @nogaleslab.bsky.social · 26/11/2024

Hello Bluesky, the Nogales lab is very excited to join this growing community 🦋 We look forward to sharing our work here and to connect with other scientists!

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the Node @the-node.bsky.social · 26/11/2024

Hello #SciSky 🧪! We're the Node, a community site for developmental and stem cell biologists, hosted by @dev-journal.bsky.social This is your site: once you’ve registered, you can share your blog post, job advert or event notice with the #DevBio and #StemCell community. thenode.biologists.com

thenode.biologists.com

Homepage - the Node

Welcome to the Node The Node is a place to read, write and interact with a global community of developmental and stem cell biologists. This is your site:

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Matt Sikora @mjsikora.bsky.social · 25/11/2024

Public Service Announcement: Check colorblind-compatibility in Illustrator! Under 'View', 'Proof Setup' you can selected a colorblindness type to view your image in that spectra. Click 'Proof Colors' after to remove filter. We chose pink/green, yellow/blue here for accessibility (PMID 38112643).

Screen capture of an Adobe Illustrator window in standard viewing mode (that is, without colorblind filter applied).

Screen capture of an Adobe Illustrator window with 'View' menu pulled down, showing selection of a relevant colorblindness filter being applied.

Screen capture of an Adobe Illustrator window with the previous image in a protanopia-type colorblindness mode applied.

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Darren Dahly @statsepi.bsky.social · 25/11/2024

And as this gains attention outside of scientific circles, as it surely will, @deevybee.bsky.social will undoubtedly face a great deal of harassment. Other fellows of the @royalsociety.bsky.social will have to decide whether she faces it alone or not.

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Fil Bednar @filbednar.bsky.social · 25/11/2024

This is a tour-de-force review for anyone semi-seriously interested in chromatin biology! It discusses functionality of chromatin within the physical constraints of its structure and folding! Well worth the read! (and it took me four hours to parse through it and think about it. I read slowly…)

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Fil Bednar @filbednar.bsky.social · 24/11/2024

Early morning summit - Bell Rock Trail, Sedona, Arizona

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Michael Baym @baym.lol · 21/11/2024

The first review article from my lab, helmed by @celiasouque.bsky.social, "From Petri Dishes to Patients to Populations: Scales and Evolutionary Mechanisms Driving Antibiotic Resistance" is now online and open access at Annual Reviews Microbiology: www.annualreviews.org/content/jour...

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Jeremy Berg @jeremymberg.bsky.social · 22/11/2024

PIONEERS When I assumed the position as Director of NIGMS in 2003, Dr. Zerhouni's project for stimulating activities across NIH, The NIH Roadmap for Medical Research, was under active development. The Roadmap included a range of different funding opportunities. 1/n www.science.org/content/arti...

science.org

NIH's Roadmap to the Future

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Tim Triche, Jr.🔰 @timtriche.bsky.social · 22/11/2024

If you don’t know about Ben Barres’ scientific legacy, here is a magnificent recounting of just one facet. Ben Barres was a true pioneer in so many different ways (Barres’ demonstration of immune complement mediated synaptic pruning in brain development is 🤯) And if you do, please help document it!

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Marc Besselink @marcbesselink.bsky.social · 20/11/2024

Today #JAMAsurg: long term outcomes #ESCAPE RCT: early #surgery remains superior to #endoscopy first in pts with wide-duct #chronic #pancreatitis ✅ Lower Izbicki pain scores ✅ Lower number of reinterventions ✅ Lower VAS pain scores ✅ Higher patient satisfaction ▶️ jamanetwork.com/journals/jam...

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Fil Bednar @filbednar.bsky.social · 21/11/2024

Today is the World Pancreatic Cancer Day. Although we have slowly increased 5-year survival from 5% to 12-13% in the last 20 years, there are reasons for optimism: - KRAS inhibitors - tumor vaccines - more effective chemotherapy - surgery for oligometastatic dz And much more! #MedSky #SurgSky

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Lucia Walinchus @walinchus.bsky.social · 18/11/2024

I read, um, a bit. Usually about a book a week. And these are, IMHO, the top ten books for data journalists or anyone curious about new ways of finding great stories🧵: (I will share more genres later.) Please LMK if there are others you would recommend! #Rstats #journalism #news

A chart of pages read per year, which about ~15,000 pages per year

A pie chart showing 63% nonfiction books

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Marlowe Tessmer @marlowetessmer.bsky.social · 20/11/2024

Clinical Cancer Research is now accepting nominations for our Early Career Award. Award recipient will be invited to the Journals Reception & the President’s Reception during the AACR Annual Meeting. A cash prize of $1,500 & a certificate will be given to the awardee. Find out more. bit.ly/3ANzCow

bit.ly

Early Career Award | Clinical Cancer Research | American Association for Cancer Research

Early Career Award | Clinical Cancer Research | American Association for Cancer Research .aacrcontent .banner{ width: 100% margin: -20px; } .aacrcontent .banner-sm{ ...

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Jeremy Berg @jeremymberg.bsky.social · 20/11/2024

A thread on NIH Reorganization and the Scientific Management Review Board (SMRB) Disclosure: I was involved with the SMRB since its inception and have very strong feelings about how it was used, misused, and abandoned. My passion on these issues will undoubtably show through. 1/n

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Jeremy Berg @jeremymberg.bsky.social · 20/11/2024

Ruth Kirschstein was an amazing person. She was deeply caring, had an incredible work ethic, high standards, and tremendous leadership skills. She was the first woman to lead an NIH Institute and served as Acting Director of NIH twice. Free biography of Dr. K. at www.nih.gov/sites/defaul... 5/n

nih.gov

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Lee Ocuin, MD, FACS @thenotorioushpb.bsky.social · 15/11/2024

1. Every patient with a suspected HPB malignancy should be evaluated by an HPB surgeon. The patient deserves an expert opinion. 2. In adults, jaundice is a surgical disease until proven otherwise (that’s easy based on LFT pattern). #surgsky 🦋

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