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Functional Genomics Center Zurich

@fgcz-en.bsky.social
527 followers 102 following 35 posts

Functional Genomics Center Zurich (FGCZ) is a joint platform of the ETH Zürich and the University of Zurich. #genomics #proteomics #metabolomics Check us out on LinkedIn: tinyurl.com/fgczlinkedin

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Functional Genomics Center Zurich @fgcz-en.bsky.social · 17/03/2026
🚀 New Tool: rctd-py is here! We’ve ported the gold-standard RCTD algorithm to #Python & @pytorch.org. Deconvolve #spatial transcriptomics in minutes, not hours. 🔹 4x GPU speedup (L40S) 🔹 99.7% concordance with R spacexr 🔹 Native AnnData/Scanpy support 🔹 Works on CPU too 💻: tinyurl.com/ths57tfd
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 10/03/2026
Calling #ETH & #UZH students! 🧬 Present your #OMICS research at FGCZ’s #StudentsOnStage this June. Best presentation wins a prize! 🏆 ⏳ Deadline: May 15, 2026 🔗 Submit abstract: tinyurl.com/3vejybk3
flyer for students on stage event
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 02/02/2026
Kick off 2026 with a deep dive into single-cell science! 🚀 Join FGCZ & BD Biosciences on March 9 in Zurich for the BD Rhapsody™ Science Days. Featuring: 🔬 Dr. Simone Picelli (IOB, Basel) 🧬 @mylliabio.bsky.social 🩺 Dr. Marc Beyer (DZNE, Bonn) ✨ Dr. Luciano Martelotto (BD) 🔗 tinyurl.com/wbffw5an
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 18/11/2025
Our proteomics experts Sibylle Pfammatter and Christian Panse attended HUPO 2025 in Toronto, presenting 3 posters on #glycosylation, #phosphorylation & integrative #PTM analysis. Great reconnecting with the community! #HUPO2025
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 03/11/2025
First #Spatial #Proteomics course complete! 🎉 Hands-on #LCMS & #MALDI-MS training for young researchers 🔬👩‍🔬 Thanks to our instructors Sibylle Pfammatter, Antje Dittmann, Claudia Fortes as well as all students for joining. Stay tuned for future FGCZ training courses! 📢
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 28/10/2025
🧬 Join us Nov 4, 14:00-16:30pm CET at FGCZ for a seminar on AVITI24™ sequencing! Discover Direct In-Sample Sequencing (no library prep!) & new multiomics applications. 🎤 Speaker: Wilfred van IJcken, PhD 📍 Y59-G30, FGCZ 🥐 Refreshments provided Details & registration: tinyurl.com/49bxkffy
Image of Aviti24 provided by Element Biosciences: https://www.elementbiosciences.com/products/aviti24
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 28/10/2025
🧪 FGCZ proteomics events this autumn ℹ️ Bruker Go Local Zurich (Nov 19) ℹ️ Quantitative Proteomics workshop (Nov 25, 3-5pm) ℹ️ Introduction to Proteomics Data Analysis course (Dec 16-18). Limited spots—first-come basis. Further info & registration at 🔗 fgcz.ch/news-and-eve...
fgcz.ch
FGCZ Seminars
Upcoming presentations & seminars being held at the FGCZ
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 12/09/2025
🧬 Exciting hybrid seminar at FGCZ! @singleronbio.bsky.social expert Baraa Altaha will present their cutting-edge single-cell tech - from tissue preservation to bioinformatic analysis. 🎁 Free kit lottery + sponsored lunch! 📅 Sep 30, 12-14:30 📍 UZH Irchel (Y59-G30) Register: tinyurl.com/3a98ec5d
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 12/09/2025
🧑‍🏫 FGCZ course round-up! - DNA Next Gen #Sequencing (Sep 8-12) - #Spatial #Transcriptomics Analysis (Oct 6-9) - #Proteomics workshop: Interaction & Quantitative (Oct 14) - Spatial Proteomics with #MassSpec (Oct 27-30) Perfect for researchers wanting to level up their omics. 🔗 tinyurl.com/mr2aan5s
tinyurl.com
FGCZ Seminars
Upcoming presentations & seminars being held at the FGCZ
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 10/09/2025
🚀 FGCZ hosts 10x Genomics User & Tech Day! Join us to discover how single-cell, spatial, and in situ tech can advance your research and see cutting-edge applications. Free but registration required! 📅 Sep 17, Office hours 9-12, lunch & seminar 12-17 📍 UZH Irchel Y59-G30 🔗 tinyurl.com/vhypvnu3
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 05/09/2025
🥩🧪 Major breakthrough in #lab-grown beef! @ethz.ch researchers led by Prof. Ori Bar-Nur cracked the code for producing thick, 3D muscle fibers in cow. Shoutout to former/current FGCZers @adhideb.bsky.social + @blauenkaiser.bsky.social for their contributions & congrats! 🔗 tinyurl.com/d84s9spv
ethz.ch
On track to produce better lab-grown burgers
The cultivation of thick muscle fibres from bovine cells in the lab has long been a challenge for scientists. Researchers from ETH Zurich have now successfully tackled this issue – with the goal of on...
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 05/09/2025
🧬💻 Bioinformatics spotlight! Our Bioinformatics Unit brings together genomics, proteomics/metabolomics, and BFabric expertise. 🔬 What we offer: - IT infrastructure support - Omics data analysis tools & services - Custom apps & tailored analyses 🔗 Check out our video: tinyurl.com/y6t6enu7
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 01/09/2025
🧪 #Metabolomics Week spotlight! Our Metabolomics Unit, led by @alaaothman.bsky.social, offers end-to-end metabolite analysis support - from experimental design to data interpretation. Services include #lipidomics, targeted & untargeted #metabolite analysis. 🔗 tinyurl.com/5a74hrpn
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 28/08/2025
🧬 Proteomics Week spotlight! Our expert team led by @paolonanni.bsky.social offers complete #proteomics support - from experimental design to data analysis. Services include protein characterization, PTM analysis, interaction studies, spatial proteomics & more Watch our video: tinyurl.com/ezb8s2s6
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 11/08/2025
🧬 Meet our #Genomics Unit! Led by @catharineaquino.bsky.social, our team specializes in #ngs, #single-cell transcriptomics, #spatial gene expression, #long-read sequencing & genome engineering. From DNA to RNA to protein to metabolites! Video 🔗 learn more about our services: tinyurl.com/zemh8bsy
tinyurl.com
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 08/08/2025
🎉 New Illumina MiSeq i100 now live at Genome Engineering & Measurement Lab (GEML) at @ethz.ch Hönggerberg Ready for walk-up access - book via B-Fabric for amplicons, plasmids & small genomes 📍ETH Hönggerberg, HCI 🗓 Booking: fgcz-bfabric.uzh.ch/bfabric/ 📧 Questions: sequencing@fgcz.ethz.ch
Image of the Illumina MiSeq i100 sequencer
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Reposted by Functional Genomics Center Zurich
Catharine.Aquino @catharineaquino.bsky.social · 07/08/2025
Big thanks to Monica Manotas for visiting the @fgcz-en.bsky.social in your very first week as CEO of Tecan. Nothing like jumping straight into customer visits (starting with the nicest customer, of course 😇 ) and what a fantastic way to kick off the new role!
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 06/08/2025
🔬Ever wondered what goes on inside one of Switzerland's leading #omics core facilities? Join us for an exclusive behind-the-scenes tour of the Functional Genomics Center Zurich! Supporting researchers from @ethz.ch, UZH, and beyond across #genomics, #proteomics & #metabolomics. 🔗 fgcz.ch
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 13/06/2025
🎉 Second Student-on-Stage event was a huge success! Congrats to: 🥇 Priska Flury 🥈 Emma Alessandri 🥉 Andrea Roggo & all other brilliant presenters who delivered amazing talks! Thanks to organizers Sibylle & Martina, jury & helpers. Already excited for year 3! 🔬✨ We hope to see you then. 🔍
Welcoming students on stageNetworking and sharing thoughts during coffee breakThe three presentersGroup picture of all presenters
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 02/06/2025
🚀 Students on Stage event next week! 📆Wed June 11, 8:30-14:30 📍FGCZ (UZH Irchel, Y59) Students presenting cutting-edge research from #spatialtranscriptomics to #cancer #therapeutics. Register: tinyurl.com/unead4e8 Thanks to sponsors Nikon & Felfel! #Science #Research
Flyer of Students on Stage at FGCZ
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 28/05/2025
🧬 New study in Gen. Bio.! We tested how RNA input & PCR cycles affect duplication rates across 4 sequencers. ↘️ RNA = ↗️ duplicates = ↘️ diversity. Key for optimizing RNA-seq protocols! Thanks + congrats to @catharineaquino.bsky.social @nataliazajac.bsky.social + collaborators! 🔗 tinyurl.com/bdcuen59
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 22/05/2025
🧬 FGCZ 10X Genomics Workshop Single-cell analysis on the 10x Cloud Analysis platform: from CellRanger to Loupe to community tools! Discuss with 10x Applied Bioinformatics team + FGCZ bioinformaticians. 📆June 12, 9:00-15:30 📍UZH Irchel Y59-G30 Limited spots—register now! tinyurl.com/4wb3rxj5
tinyurl.com
10x Genomics single cells data analysis day: Don't miss this hands-on workshop!
Title: Hands-on workshop of the single-cell analysis, from Cloud to Loupe to Community-Developed Tools Date: Wednesday 11th and Thursday 12th June 2025 Time: 9.00 to 15.30 Make your choice: Geneva...
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 05/05/2025
🔬 Exciting news! Our #metabolomics team led by Dr. Alaa Othman has published another paper! Prof. Kopf's lab at ETHZ discovered a new metabolic role for #peroxisomes that could lead to treatments for rare diseases. Read the paper: tinyurl.com/yc7u5cu9 Our services: tinyurl.com/5yfdcdc9
tinyurl.com
Peroxisomes are critical for a unique metabolic demand and survival of alveolar macrophages
Tissue-resident macrophages (TRMs) populate throughout various tissues, and their homeostatic metabolism is heavily influenced by these microenvironme…
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 25/03/2025
📢 Announcing our GEO Uploader tool! Simplifies deposition of sequencing data to GEO repository by automating aggregation, upload & metadata entry in one place. Use it now for FGCZ-generated data: geo-uploader.fgcz.uzh.ch And stay tuned: we will be open-sourcing the code soon.
screenshot of the dashboard of the FGCZ Geo Uploader
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Reposted by Functional Genomics Center Zurich
Rolf Kümmerli @rkmicrobes.bsky.social · 25/02/2025
New preprint! How S. aureus copes with inhibitory compounds secreted by P. aeruginosa. By @schluk.bsky.social. Great collaboration with @fgcz-en.bsky.social www.biorxiv.org/content/10.1...
biorxiv.org
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 12/03/2025
📣 Collaborative Proteomics Publications 🧪 New 2025 studies from FGCZ Proteomics team + research partners: tinyurl.com/yfy7umph (w/ Schnyder group) tinyurl.com/ah8mncf4 (w/ Visentin lab) tinyurl.com/yrj2pdpp (w/ Lösle) Congrats to all involved! If you, too, want to work with us, check out the link:
fgcz-intranet.uzh.ch
FGCZ Intranet | ProteomicsServiceEntryPage
FGCZ Intranet
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 12/02/2025
Join EuPA Open Lab Days! Virtual tour of 8 European #proteomics #core facilities in #Proteopolis. Discuss lab management, protocols, data analysis & more. Register now! 🔗 tinyurl.com/EuPACore4Life 📅 25/02/2025, 15:00 CET
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 27/01/2025
Just published in J. Proteome Research: "prolfquapp", a new #opensource tool simplifying differential expression analysis in quantitative #proteomics. Developed by FGCZ for UZH & @ethzurich.bsky.social. TY to the amazing FGCZ team for their collaboration! #Bioinformatics tinyurl.com/4nd9jhj7
tinyurl.com
prolfquapp ─ A User-Friendly Command-Line Tool Simplifying Differential Expression Analysis in Quantitative Proteomics
Mass spectrometry is a cornerstone of quantitative proteomics, enabling relative protein quantification and differential expression analysis (DEA) of proteins. As experiments grow in complexity, invol...
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 13/01/2025
We're excited to announce our NEW #Omics in #Oncology course, aimed to foster interaction within the oncology community between Switzerland and the Netherlands! 🔬FGCZ/Utrecht University 📅 Feb-Apr 2025 🌍 Online collab 🧬 Omics & bioinformatics Info: tinyurl.com/bdes8sm6
Powerpoint slide explaining salient details about omics course
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 06/01/2025
Check out our latest publication "A Multiyear Longitudinal Harmonization Study of #QualityControls in #MassSpectrometry #Proteomics #CoreFacilities"! Over 4 years, we built a #QC framework across the Core4Life proteomics cores, gathering 9000+ files from 30 LC-MS systems. tinyurl.com/fnb93th3
tinyurl.com
A Multiyear Longitudinal Harmonization Study of Quality Controls in Mass Spectrometry Proteomics Core Facilities
Quality control procedures play a pivotal role in ensuring the reliability and consistency of data generated in mass spectrometry-based proteomics laboratories. However, the lack of standardized quali...
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 19/12/2024
🎉 We wrapped up our final 2024 course: "NGS Applied to Metagenomics"! Participants explored #metagenomics & gained hands-on #bioinformatics skills. Many thanks to our experts Anna, Jonas, Natalie, Maria, & Witold, and to all participants for your efforts! Stay tuned for future courses.
Witold pointing out something to the classStudents and instructors pose for a photoInstructor poses with students for a photo
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 18/12/2024
Huge congratulations to Dr. Enni Markkanen & Mikiyo Weber (UZH) on their newly published cross-omics study! 🎉 🐾 With help from our experts, L. Kunz, L. Opitz, and W. Wolski, they revealed tumor-exclusive features in feline FSA for potential diagnostics/therapy. 🔗https://tinyurl.com/3wnxxpdk
Fig. 1. Overview of proteins and transcripts identified in feline fibrosarcoma and surrounding peritumoral tissue of 30 cases.
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Reposted by Functional Genomics Center Zurich
Catharine.Aquino @catharineaquino.bsky.social · 10/12/2024
The first #Illumina #Miseqi100 has landed in Europe—guess who gets the honors? Of course, it’s @fgcz-en.bsky.social! This state-of-the-art sequencer joins our fleet, driving groundbreaking genomics research for the Zurich life science community.🧬
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 12/12/2024
Are you passionate about #NGS applications and skilled in using #bioinformatics tools? We're hiring! 👊 We're looking for a bioinformatician with strong expertise in NGS data analysis and excellent programming skills. If this sounds like you, join us! Apply now: tinyurl.com/4dd2477r
tinyurl.com
Bioinformatician for NGS Applications including Long Reads
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 03/12/2024
🚨 Exciting opportunity! Join our "Next-Gen Sequencing in #Metagenomics" course, happening soon. Perfect for pros & students diving into cutting-edge tech! 📅 Dec 9-13, 2024 📍FGCZ, UZH Irchel tinyurl.com/bdz2v8ey or email mariadomenica.moccia@fgcz.ethz.ch for more info.
tinyurl.com
Metagenomics Course
Next Generation Sequencing Applied to Metagenomics (BIO638)
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 02/12/2024
#Metabolomics is fun! 🎉 Our 2024 Mass Spec Metabolomics course was a hit! Participants mastered #LCMS, solved metabolic puzzles with creativity & #AI tools like ChatGPT. Huge thanks to our fantastic team & guest lecturers for making it a success! 🙌 tinyurl.com/3p3nv7zp
course participants and lecturers pose in a meeting room at the functional genomics center
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Reposted by Functional Genomics Center Zurich
Catharine.Aquino @catharineaquino.bsky.social · 30/11/2024
Check out this cool paper from the lab of Jacob Corn using @nanoporetech.com to look at large scale genomic alterations following genome editing. A big thank you for acknowledging the contributions of @fgcz-en.bsky.social team members #genomics www.nature.com/articles/s41...
nature.com
Genome editing with the HDR-enhancing DNA-PKcs inhibitor AZD7648 causes large-scale genomic alterations - Nature Biotechnology
A compound that enhances homology-directed repair in CRISPR editing leads to genome instability.
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Reposted by Functional Genomics Center Zurich
Catharine.Aquino @catharineaquino.bsky.social · 27/11/2024
I’m sharing again the link to the Genomics Core Facilities starter pack that I put together as I added more accounts and feeds today go.bsky.app/HiWxZZc
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 26/11/2024
We extend a warm welcome to our Core For Life | C4L colleagues visiting Zürich for our annual #C4L meeting. We thank you for the fruitful discussions yesterday, and look forward to the same today! #genomic #proteomics #metabolomics #bioinformation #omics #automation
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Functional Genomics Center Zurich @fgcz-en.bsky.social · 20/11/2024
Congrats to Laura Hinte and Daniel Castellano from the @vonmeyennlab.bsky.social for their publication in Nature! We are proud to have contributed to the #sequencing effort. Special shout-out also to our bioinformaticians who were directly involved with this work, Adhideb Ghosh and Falko Noé.
nature.com
Adipose tissue retains an epigenetic memory of obesity after weight loss - Nature
Stable epigenetic changes indicate the existence of an obesogenic memory in mouse adipocytes that primes cells for pathological responses in an obesogenic environment and potentially contributes to th...
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