npj Systems Biology and Applications - MIRO1 mutation leads to metabolic maladaptation resulting in Parkinson’s disease-associated dopaminergic neuron loss

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The single-cell technology company, which previously focused on China and Europe, is hoping to expand into the US and the Middle East markets.

Heterogeneity determines cell fate and phenotypic variability, but its molecular mechanisms are not well understood. Here the authors present a high-resolution single-cell yeast transcriptome atlas of...

The PI3K-Akt signaling pathway of the microbiotagut-brain axis is involved in forced loss induced by forced reduction of social rank in mice, and influences the outcome of forced loss.

Die Lokalzeit aus Düsseldorf ist das regionale Magazin im WDR Fernsehen für den Großraum Düsseldorf.

Background New postoperative atrial fibrillation (POAF) occurs in about 40% after cardiac surgery. Mineralocorticoid receptor antagonists (MRA) are known to reduce chronic atrial fibrillation (AF) dev...

Mutations in the gene encoding Miro1, a mitochondrial GTPase, have been identified in patients with Parkinson’s disease. Using neuronal cell cultures and m

New AI model takes minutes rather than days to predict how a specific DNA sequence will arrange itself in the cell nucleus.

Single-cell RNA sequencing (scRNA-seq) using metabolic RNA labeling enables detailed analysis of dynamic gene expression within single cells. However, most studies are limited to in vitro settings, re...

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Mitochondria with mutations in their DNA from cancer cells can be transferred to T cells in the tumour microenvironment, which leads to T cell dysfunction and impaired antitumour immunity.

Singleron introduces Tensor, the first instrument for full single cell RNA-seq automation,from cell suspension to sequencing-ready library.

Signal Transduction and Targeted Therapy - Dual targeting PD-L1 and 4-1BB to overcome dendritic cell-mediated lenalidomide resistance in follicular lymphoma

Drought significantly affects forests and woody crops by limiting their growth, increasing their susceptibility to diseases, and reducing productivity. Wood anatomical plasticity is a crucial adaptive...

A foundation model learns transcriptional regulatory syntax from chromatin accessibility and sequence data across a range of cell types to predict gene expression and transcription factor interactions...

Transform Single Cell Workflow with Automation at FoG2025, London

Nanoplastics (NPs), plastic particles ranging from 1–1000 nm, form through weathering and are considered more hazardous than larger plastics due to th…

IBDverse - the largest single-cell RNA sequencing dataset of terminal ileal biopsies

A new single-cell atlas of gene expression provides insights into the patterning of the neural plate of mice.

The FocuSCOPE Single Cell Targeted Capture Kit utilizes targeted customized probes for simultaneous whole transcriptome sequencing.

As 2024 comes to an end, let's look back at the most impactful publications this year from researchers using Singleron’s products.

Samples from 19 patients with non-small-cell lung cancer treated with a combination of chemotherapy and immune checkpoint blockade are profiled with single-cell RNA sequencing and spatial transcriptom...

Nine scientists extol their favorite cells, highlighting the vast variety and the startling behaviors of the basic units of life.