iiinova — where your digital self keeps evolving

Reposted by Natalia Zajac

Silvia Prieto @silviaprietob.bsky.social · 31/08/2026

Come visit my poster G.54 if you are at #eccb2026 ! 😃 #synteny #GO #animals #genes

Natalia Zajac @nataliazajac.bsky.social · 28/05/2026

Mitochondrial and nuclear genomes often tell different evolutionary stories. In our new Molecular Ecology paper, we use whole-genome Pool-seq data to test whether selection on mito-nuclear interactions underlies this phenomenon in a New Zealand trematode parasite. doi.org/10.1111/mec....

doi.org

A Whole‐Genome Investigation of Mitonuclear Discordance in the Trematode Parasite Atriophallophorus winterbourni

Faster evolution of mitochondrial genomes relative to nuclear genomes creates selective pressure on nuclear genes involved in mitochondrial function to preserve mitonuclear compatibility required for...

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Reposted by Natalia Zajac

Joana Meier @joanameier.bsky.social · 18/05/2026

Join us for another @speciation-network.bsky.social seminar, this time on the ecological and geographical axes of speciation by Ingrid Olivares and Alexandre Siqueira on 2 June, at 10 am CEST. More details and Zoom link here: speciation-network.pages.ist.ac.at/seminar-seri...

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Reposted by Natalia Zajac

ERGA - European Reference Genome Atlas @ergabiodiv.bsky.social · 13/04/2026

💡 #KnowledgeHighlight | Learning Material: CHROMOSOME WALK by @sib.swiss www.chromosomewalk.ch/en/list-of-c... Explore open-access training materials in the ERGA #KnowledgeHub ➡️ knowledge.erga-biodiversity.eu #scicomm #learning #chromosomes

chromosomewalk.ch

List of chromosomes - Chromosome Walk

DÉCOUVREZ LE MONDE FASCINANT QUI SE CACHE AU TRÉFOND DE NOS CELLULES ...

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Reposted by Natalia Zajac

ERGA - European Reference Genome Atlas @ergabiodiv.bsky.social · 10/04/2026

📘 Did you have a chance to read our lasted @biogeneurope.bsky.social booklet Connections – Discovering Biodiversity Genomics? Explore how biodiversity and genomics come together to support species monitoring and conservation 👉 www.erga-biodiversity.eu/post/connect... Available in 3 languages:

erga-biodiversity.eu

Connections Booklet: Discovering Biodiversity Genomics

What is biodiversity? And genomics? How are they related to each other in ways that help species monitoring and conservation?Throughout 2025, the “ERGA – iBOL Europe Connections” blog post series…

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Physalia-courses@ONLINE @physaliacourses.bsky.social · 02/04/2026

🚨 Last seats alert! Join our Computational #Pangenomics online course with @andreaguarracino.bsky.social, 13–16 April, to learn how to build & analyse pangenome graphs from whole genome assemblies. www.physalia-courses.org/courses-work... #Bioinformatics #Genomics #DataScience #RStats

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Reposted by Natalia Zajac

Joana Meier @joanameier.bsky.social · 01/04/2026

In July, we will teach the 3rd biodiversity genomics course in Latin America, this time in Bogotá, following the COLEVOL meeting. We invite applications from students, postdocs and PIs from Latin America interested in learning how to analyse genomic data. biodiversitygenomicslatam.weebly.com

Flyer of the course on "Introduction to Biodiversity Genomics". All information are also here: https://biodiversitygenomicslatam.weebly.com/

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Reposted by Natalia Zajac

Physalia-courses@ONLINE @physaliacourses.bsky.social · 20/03/2026

The 2nd edition of the Computational #Pangenomics course with @andreaguarracino.bsky.social is almost full. If interested, check it out: www.physalia-courses.org/courses-work... #Pangenomics #Bioinformatics

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Reposted by Natalia Zajac

Functional Genomics Center Zurich @fgcz-en.bsky.social · 10/03/2026

Calling #ETH & #UZH students! 🧬 Present your #OMICS research at FGCZ’s #StudentsOnStage this June. Best presentation wins a prize! 🏆 ⏳ Deadline: May 15, 2026 🔗 Submit abstract: tinyurl.com/3vejybk3

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Kaiser Lab @clocksevolution.bsky.social · 23/02/2026

"Der #Mond, das #Meer und die #Mücke - eine Reise durch die Welt der Biologischen #Uhren" Vortrag von Dr Tobias Kaiser MPl für Evolutionsbiologie, #Plön Mittwoch, 4.3.2026, 19 Uhr Eutiner Landesbibliothek, Schlossplatz 4, #Eutin #SHUG #CAU #WissKomm #Chronobiologie #Evolution #Ökologie #Genomik

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Andrea Guarracino @andreaguarracino.bsky.social · 06/02/2026

Looking for a postdoc to build my new lab at TGen (Phoenix, AZ) focused on pangenome methods for cancer and complex disease. Full stack — from pangenome assembly and compression to association studies and somatic variant discovery. Reach out if interested! guarracinolab.github.io#join

guarracinolab.github.io

Guarracino Lab | Pangenome Research

We develop methods to build and analyze pangenomes, with applications in cancer and complex disease. Translational Genomics Research Institute, Phoenix, AZ.

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Reposted by Natalia Zajac

John Lovell @jotlovell.bsky.social · 06/02/2026

We’re excited to share the Pan-genomes Doorstep Meeting @ #PEQG26! Join this 3-hour workshop on evolutionary applications of pangenomics, covering construction, analysis, phylogenetics, annotation & graph QC. Register separately or as an add-on to PEQG: genetics-gsa.org/peqg-2026/do...

genetics-gsa.org

Pan-genomes Meeting - 2026 Population, Evolutionary, and Quantitative Genetics Conference

Visit our website to learn more.

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Reposted by Natalia Zajac

John Lovell @jotlovell.bsky.social · 30/01/2026

This article is now published! academic.oup.com/nargab/artic... We’ve added a few new analyses. First off, we show that, while gene presence absence variation (PAV) scales with evolutionary distance in both plants and animals, the base level and rate of accrual are both twice as high in plants.

academic.oup.com

Evolutionary and methodological considerations when interpreting gene presence–absence variation in pangenomes

Abstract. While graph-based pangenomes have become a standard and interoperable foundation for comparisons across multiple reference genomes, integrating p

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Natalia Zajac @nataliazajac.bsky.social · 12/01/2026

Want to learn more about pangenomics or find solutions to problems you are already facing? Join us on 07–13 June 2026 at the EMBO Practical Course on Pangenomics, in the Campania region, Italy. Applications are now open and close on 3 February! Find out more: meetings.embo.org/event/26-pan...

meetings.embo.org

Pangenomics

Pangenomics has emerged as a transformative paradigm in genomics, moving from single linear reference genomes to pangenomes that capture the full spectrum of genetic variation within species. Recent…

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MPI for Evolutionary Biology @mpi-evolbio.bsky.social · 06/01/2026

New milestone for wall lizards: 10 chromosome-level reference genomes released by MPI EvolBio, Wellcome Sanger Institute & collaborators — now >50% of described Podarcis species have high-quality references. A backbone resource for evo & pop genomics. www.evolbio.mpg.de/3851900/ten-...

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Robin Pranter @robinpranter.bsky.social · 12/12/2025

PhD position on the #evo-devo of lizard color patterns, exploring how pigment cells build diverse patterns using developmental and genomic tools. Links to more info about the project and the researchschool below. Please share with interested students!

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Sina Majidian @sinamajidian.bsky.social · 13/07/2025

APAV: An advanced pangenome analysis and visualization toolkit journals.plos.org/ploscompbiol...

Fig 1. Overview of APAV pipeline.

(A) Workflow for PAV calling and consequent analysis. The coordinates of the target region are first extracted from a GFF file or BED file. The coverage of both the whole region and the element region is calculated based on the BAM files. The PAVs are determined according to their coverage, and interactive reports are generated. Subsequent analyses can be performed using the PAV tables, including genome size estimation, classification and statistical analysis, phenotypic association analysis, and visualization of elements. (B) Interactive analysis reports. The PAV report presents PAV tables, coverage data, pangenome sequences, genome annotation, and sequence alignments. The sample report presents sample tables, phenotype information, and real-time PAV analysis results.

https://doi.org/10.1371/journal.pcbi.1013288.g001

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Functional Genomics Center Zurich @fgcz-en.bsky.social · 28/05/2025

🧬 New study in Gen. Bio.! We tested how RNA input & PCR cycles affect duplication rates across 4 sequencers. ↘️ RNA = ↗️ duplicates = ↘️ diversity. Key for optimizing RNA-seq protocols! Thanks + congrats to @catharineaquino.bsky.social @nataliazajac.bsky.social + collaborators! 🔗 tinyurl.com/bdcuen59

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Reposted by Natalia Zajac

Sina Majidian @sinamajidian.bsky.social · 22/05/2025

Interesting idea: instead of building the pangenome graph from scratch for new samples, dynamically update it by introducing new nodes/edges from long reads biorxiv.org/content/10.1101/2025.02.07.637057 PALSS-Pangenome Graph Augmentation from Long-reads Specific Strings github.com/ldenti/palss

Fig. 1. Method overview. (i) Pangenome graph is sketched using solid anchors (k-mers) and its distin- guished paths, i.e., haplotypes paths, are indexed using an FMD-index. (ii) Specic strings are computed from long reads and (iii) anchored to the graph using solid anchors. (iv) Based on their anchoring, an- chored specic strings are clustered. (v-vi) Each cluster, composed of several specic strings anchored to (mostly) the same subgraph and which may contain sequencing errors (the red Xs), is assembled and locally realigned back to the corresponding subgraph (in case of a diploid locus, two consensuses are created and analyzed). (vii) The base-level alignments are nally used to augment the initial pangenome graph.
https://www.biorxiv.org/content/10.1101/2025.02.07.637057v1.full-text

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Natalia Zajac @nataliazajac.bsky.social · 19/05/2025

Last week I had an incredible time at #MemPanG25! I was honoured to have a chance to give a talk! It was great to learn what is new and what is coming in the field of pangenomics. Huge thanks to @thinks.lol , @andreaguarracino.bsky.social, and the whole organizing team for making it happen!

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Natalia Zajac @nataliazajac.bsky.social · 28/04/2025

Great to see our research on heterogenous and novel transcript expression in single cells of patient-derived clear cell renal cell carcinoma organoids published as part of Long-read sequencing special issue in Genome Research, along fantastic collection of articles on long reads!

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MPI for Evolutionary Biology @mpi-evolbio.bsky.social · 19/03/2025

We offer 2 PhD Positions in Evolutionary Biology! 1️⃣ Evolutionary Developmental Biology – Craniofacial evolution. (March 31, 2025) 2️⃣ Evolution of Polygenic Traits – Genetic adaptation in Drosophila. (April 30, 2025) More here: www.evolbio.mpg.de/1639156/Job_... #PhD #EvoDevo #Genetics

evolbio.mpg.de

Current job offers

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