Reposted by Felix BayerlReese Richardson @reeserichardson.bsky.social · 05/06/2026The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes: 🖌️ Dozens more images with duplications or painting 🖨️ Hundreds of blots that all share the same background (behold slideshow below) 18590367
Reposted by Felix BayerlOded Rechavi @odedrechavi.bsky.social · 15/10/2025BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇) 56495185
Reposted by Felix BayerlAdrian Liston @labliston.bsky.social · 19/09/2025For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper? You got it: currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...currentprotocols.onlinelibrary.wiley.com 1015869
Reposted by Felix BayerlMiranda Hunter @mrndhntr.bsky.social · 27/08/2025My recent postdoctoral work is out today in @nature.com! We found that physical confinement makes melanoma cells more invasive and drug tolerant. Thanks to all who made this work possible @whitefishlab.bsky.social @mskcancercenter.bsky.social #NIH #NCI www.nature.com/articles/s41...nature.comMechanical confinement governs phenotypic plasticity in melanoma - NatureMechanical confinement of cancer cells at the tumour–microenvironment interface induces phenotype switching through chromatin remodelling by HMGB2, leading to a more invasive and drug-resistant state ... 66924
Reposted by Felix BayerlNature @nature.com · 19/07/2025Long-awaited results suggest that mitochondrial donation can prevent babies from inheriting diseases caused by mutant mitochondria go.nature.com/44GsxT2go.nature.com‘Landmark’ study: three-person IVF leads to eight healthy childrenNature - Long-awaited results suggest that mitochondrial donation can prevent babies from inheriting diseases caused by mutant mitochondria. 17414
Reposted by Felix BayerlEric Topol @erictopol.bsky.social · 22/02/2025This week was the 1st publication using our immune cell sequencing to accurately make medical diagnoses. It has enormous implications, as I've reviewed here erictopol.substack.com/p/the-first-... @scottboydlab.bsky.social @science.org @anshulkundaje.bsky.social @maximzaslavsky.bsky.socialerictopol.substack.comThe First Diagnostic ImmunomeA Big Step Forward By Sequencing B and T Cell Receptors Plus A.I. 735786
Reposted by Felix BayerlWaggoner Lab @labwaggoner.bsky.social · 13/02/2025KLF2 maintains lineage fidelity and suppresses CD8 T cell exhaustion during acute LCMV infection www.science.org/doi/10.1126/... @science.org @nikjoshilabyale.bsky.social 02814
Reposted by Felix BayerlScience Magazine @science.org · 27/01/2025A new #ScienceImmunology Review discusses the mechanisms through which dendritic cells influence cytotoxic CD8+ T cell responses against cancer. scim.ag/3PU7hRoscim.agArchitects of immunity: How dendritic cells shape CD8+ T cell fate in cancerDC–T cell interactions during priming influence CD8+ T cell fate, and DCs subsequently sustain T cell responses against cancer. 310633
Reposted by Felix BayerlWaggoner Lab @labwaggoner.bsky.social · 23/01/2025Two-layered immune escape in AML is overcome by Fcγ receptor activation and inhibition of PGE2 signaling in NK cells @bloodjournal.bsky.social doi.org/10.1182/bloo... 021
Reposted by Felix BayerlMSK Department of Medicine @mskdeptofmed.bsky.social · 17/01/2025Breaking: The FDA approved datopotamab deruxtecan for unresectable or metastatic HR+/HER2-negative #breastcancer. Congrats to @mskcancercenter.bsky.social's Komal Jhaveri, one of the lead accruers of the TROPION Breast 01 trial. www.fda.gov/drugs/resour...fda.govFDA approves datopotamab deruxtecan-dlnk for unresectable or metastatiOn January 17, 2025, the Food and Drug Administration approved datopotamab deruxtecan-dlnk (Datroway, Daiichi Sankyo, Inc.), a Trop-2-directed antibody and topoisomerase inhibitor conjugate, for adult... 062
Reposted by Felix BayerlEnfu Hui @enfuhui.bsky.social · 04/01/2025Thrilled to share our @sciimmunology.bsky.social paper! We report that rodent PD-1 is weaker than human PD-1 (reduced ligand binding & signaling) & lacks a conserved vertebrate motif. Humanizing mouse PD-1 disrupts T cell anti-tumor responses, raising many questions. science.org/doi/10.1126/... 23816
Reposted by Felix BayerlWaggoner Lab @labwaggoner.bsky.social · 31/12/2024β-adrenergic signaling is a key driver of metastasis & the β-blocker propranolol reduces metastasis through monocyte-dependent activation of cytotoxic CD4+ T cells www.researchsquare.com/article/rs-5... 083
Reposted by Felix BayerlYüksel Ürün @yukselurun.bsky.social · 30/12/2024Immunotherapy shows sex bias—men respond better; women face more severe AEs. Understanding sex hormones, chromosomes, and epigenetics in immunity could lead to tailored immuno-oncology strategies. #Cancer #Immunotherapy #Oncology @oncoalert.bsky.social rdcu.be/d49Mq 0259
Felix Bayerl @felixbayerl.bsky.social · 27/11/2024That was a really fun and fruitful collaboration, we learned so much from each other! Thanks again ☺️ 051
Felix Bayerl @felixbayerl.bsky.social · 24/11/2024Hello Bluesky! 👋 Here to share my work, learn from others, and talk science ☺️ 020