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Darren Fayne

@fayned.bsky.social
133 followers 215 following 15 posts

Assistant Professor in Computational Chemistry. Dublin City University. Open to collaboration on modulating interesting therapeutically relevant proteins t.mbjms.com/331727/4080/0?po=6456&a…

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Reposted by Darren Fayne
James Fraser @fraserlab.com · 10/10/2026
I hear so much about the growing power of predictive biology, especially in drug discovery and "co-folding". I want to see people put their GPU budget where their mouth is!
CYP3A4
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Rob Cruickshank @robcruickshank.bsky.social · 11/10/2026
Turns out these guys are real
A fish like a child would draw, no fins, just a tail an eye and a little smile
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Itai Yanai @itaiyanai.bsky.social · 10/10/2026
1. CRISPR came from basic research on bacteria. 2. Optogenetics started with a discovery in algae. 3. The GFP protein comes from jellyfish. The biggest breakthroughs all trace to scientists following their curiosity, and this is one huge reason why we must keep funding basic research!
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Peter Kenny @pwk2024.bsky.social · 09/10/2026
Opportunity for computational chemist at Bristol Myers Squibb (San Diego CA USA) ref: R1607160 #CompChem #cheminformatics #ML #ChemJobs #chemsky 🧪 bristolmyerssquibb.wd5.myworkdayjobs.com/en-US/BMS/jo...
bristolmyerssquibb.wd5.myworkdayjobs.com
Principal Scientist - Computational Sciences
At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to dis...
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Dublin City University @dublincityuni.bsky.social · 09/10/2026
DCU and the DCU Life Sciences Institute (LSI) are leading the way in pioneering cancer research. The LSI uses advanced molecular tools and drug screening to translate lab discoveries into real care, focusing on holistic patient support. Find out more: dcu.ie/lifesciences/cancer-research
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Benjamin Tausig @burrata.bsky.social · 07/10/2026
“Universities must stop falling in love with every new piece of software … that the tech industry pitches as essential. Administrators spend on software as if it is a durable investment, when all of the evidence shows that it … makes bloat worse.” globecollegetown.substack.com/p/higher-ed-...
globecollegetown.substack.com
College campuses need to be liberated from their administrators
Higher ed is being strangled by absurd and costly rules. What message is that sending to students?
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Brilliant Maps @brilliantmaps.bsky.social · 03/10/2026
Map Of The Irish Diaspora In The World brilliantmaps.com/irish-dia...
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Peter Kenny @pwk2024.bsky.social · 29/09/2026
Opportunities (2) for computational chemists at Johnson & Johnson (Beerse Belgium | Spring House PA USA | La Jolla CA USA) ref: R-100091 | closing: 11-Oct-2026 #CADD #CompChem #cheminformatics #ChemJobs #chemsky 🧪 jj.wd5.myworkdayjobs.com/JJ/job/Beers...
jj.wd5.myworkdayjobs.com
Senior Scientist, In Silico Discovery
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments...
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Manas Mahale @manasmahale.bsky.social · 27/09/2026
This Week In Cheminformatics Issue #040 is out. This week we look into RetroChimera, HDACiAP, and a long list of papers. Happy reading :) thisweekincheminformatics.substack.com/p/forty
thisweekincheminformatics.substack.com
This Week In Cheminformatics: Issue #040
RetroChimera, HDACiAP, and a long list of papers
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Manas Mahale @manasmahale.bsky.social · 20/09/2026
This Week In Cheminformatics Issue #039 is out. This week we look into the scope concept from Novartis, SB2025 & FARMA2025 datasets, TDiMS and a long list of papers. Happy reading :) thisweekincheminformatics.substack.com/p/thirty-nine
thisweekincheminformatics.substack.com
This Week In Cheminformatics: Issue #039
The Scope Concept from Novartis, SB2025 & FARMA2025, TDiMS and a long list of papers
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Hetan Shah @hetanshah.bsky.social · 17/09/2026
AI is screwing up journal papers: Journal editor asks authors of 10 submitted papers to meet and discuss their paper. Of the 7 that showed up, 3 were unable to answer basic questions about the paper and 3 had difficulty when asked further questions on technical details… medium.com/@TmlrOrg/ask...
medium.com
Asking Authors About Their Own Papers
By Nihar B. Shah
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Rhodri Cusack @rhodricusack.bsky.social · 10/09/2026
We're hiring! 2 postdocs + 3 PhD students to join InfantNeuroAI at Trinity College Dublin: awake infant fMRI & OPM-MEG, plus computational models of how infants learn. Aims: understand infant visual cognition, infant neuroimaging methods, more energy-efficient learning 🧵 www.cusacklab.org/vacancies
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In Preparation @inprep.bsky.social · 08/09/2026
inpreparation.substack.com
40% Of PhD Now Spent Selecting ‘All Squares Containing Bicycles’
BALTIMORE, MD—A study published Tuesday in PLOS ONE found that approximately 40% of doctoral training is now spent confirming the researcher is not a robot, primarily through the selection of squares…
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Manas Mahale @manasmahale.bsky.social · 07/09/2026
This Week In Cheminformatics Issue #037 is out. This week we look into the sr-SMILES, Markush structure image to SMILES, benchmarking GNNs on ChEMBL, and a long list of papers. Happy reading :) thisweekincheminformatics.substack.com/p/thirty-seven
thisweekincheminformatics.substack.com
This Week In Cheminformatics: Issue #037
sr-SMILES, Markush structure image to SMILES, benchmarking GNNs on ChEMBL, and a long list of papers
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George Takei @georgetakei.bsky.social · 08/09/2026
Sixty years ago today, the starship Enterprise launched and with it, a vision of the future where humanity had moved beyond its divisions. I was there at the beginning, and I can tell you...
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Peter Kenny @pwk2024.bsky.social · 07/09/2026
Opportunity for industrial placement student in computational chemistry at AstraZeneca (Cambridge UK) ref: R-257921 | start: 06-Sep-2027 | closing: 02-Oct-2026 #CompChem #cheminformatics #CADD #DrugDesign #DrugDiscovery #chemsky 🧪 careers.astrazeneca.com/job/cambridg...
careers.astrazeneca.com
12 Month University Industrial Placement Student: Computational Chemistry at AstraZeneca
Learn more about applying for 12 Month University Industrial Placement Student: Computational Chemistry at AstraZeneca
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The Royal Society @royalsociety.org · 05/09/2026
#OnThisDay in 1977, NASA launched the Voyager 1 probe to study the outer solar system. It's still transmitting data, and at over 15.9 billion miles away is the most distant man-made object. In 1990, Voyager 1 took the famous 'Pale Blue Dot' image, showing Earth from over 6 billion kilometres away.
The image depicts the Voyager 1 spacecraft in space, set against a backdrop of stars and nebulous, blue cosmic clouds.A photograph of space showing scattered light beams with a small, pale dot known as Earth. This image is famously known as the "Pale Blue Dot," captured by the Voyager 1 spacecraft.
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Biophysical Society @biophysicalsoc.bsky.social · 02/09/2026
For the upcoming National Postdoc Appreciation Week, September 21–25, BPS is excited to launch Beauty in Biophysics, a new image contest celebrating the research, creativity, and unique visual perspectives of our postdoctoral community. www.biophysics.org/outreach/pos...
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Dermot Lynott @dermotlynott.bsky.social · 28/08/2026
For the avoidance of doubt, this is complete BS. if you are a post-doc (or worker of any description frankly) and you have the option of joining a union, you absolutely should.
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no.11 @no1011.bsky.social · 25/08/2026
Ireland needs to build student accomodation
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👻madeline bOoOoOoOodent👻 @oldenoughtosay.com · 25/08/2026
everybody is (rightfully) remembering her incredible charity work, the 300 million books and counting for kids, the moderna vaccine, all of it she also wrote 'I Will Always Love You' and 'Jolene' on the same dang day. absolutely peerless
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Mr Natural @neilmatheson66.bsky.social · 15/08/2026
Apocalypse Now was released #OTD 1979. Director: Francis Ford Coppola. #Filmsky
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Surly Amy @surlyamy.bsky.social · 15/08/2026
It’s still weird to me that companies that stream tv shows, want us to pay them to show us commercials.
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Gavan Reilly @gavreilly.com · 13/08/2026
Mark English didn’t just run through the line, so much as smash it to bits. Perfection.
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Manas Mahale @manasmahale.bsky.social · 11/08/2026
This Week In Cheminformatics Issue #033 is out. This week we look into Andreas's view of AI4DD, SynthEx, CheMeleon, and a long list of papers. Happy reading :) thisweekincheminformatics.substack.com/p/thirty-three
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Peter Kenny @pwk2024.bsky.social · 12/08/2026
Opportunity for machine learning scientist at onepot (South San Francisco CA USA) #ML #cheminformatics #CompChem #ChemJobs #chemsky 🧪 www.onepot.ai/careers/f8bb...
onepot.ai
Research Scientist, Machine Learning — onepot careers
onepot is automating chemistry. Our goal is to enable a self-improvement loop for chemistry by combining AI and advanced robotics. In this loop, AI
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Aaron Clauset @aaronclauset.bsky.social · 11/08/2026
Very much agree with Pieris's argument: investing public funds exclusively in research 'applications' (believing that they have greater and more immediate economic value) will destroy the real driver of economic growth: basic science is the *only* economic engine arxiv.org/abs/2608.00172
Money quote from the preprint's conclusion : "The choice being presented to the scientific community — discovery or appli-cation, curiosity or impact — is a zero-sum illusion. The researchers who pursue fundamental questions are the same ones who end up transforming medicine, defence and industry — not because they planned to, but because transformative discoveries do not respect funding categories. Fundamental research is the foundation of the building. No one sees it while the skyscraper is standing, but remove it and everything above comes down."
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Noel O'Boyle @baoilleach.bsky.social · 10/08/2026
We're still looking for candidates who are interested in working on an industry-relevant project in close collab with a major pharmaceutical company. It's a really nice opportunity for someone looking to transition to an industry position. #chemjobs #phdjobs #cheminformatics #bioinformatics
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Derek Lowe @dereklowe.bsky.social · 04/08/2026
If they would just get the journal RSS feeds working again, they can have any logo they want. Cthulu holding an Erlenmeyer flask, whatever.
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Matthew Cobb @matthewcobb.bsky.social · 23/07/2026
They really don’t and you’ll be rehiring ppl soon.
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Greg Landrum @greglandrum.bsky.social · 09/07/2026
@pubs.acs.org this is a real problem for those of us who use RSS readers to stay on top of what's appearing in your journals.
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Os Keyes @okeyes.bsky.social · 06/07/2026
Visiting my university’s new, expensively-refurbished space for startup incubators and senior management and cannot imagine a better illustration of the American university at this moment in time than a breathlessly press-released “collaboration room” featuring a single desk and chair.
A room labelled “collaboration room” featuring a single desk and chair.
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turgut keskintürk @tkeskinturk.bsky.social · 06/07/2026
data visualization is my passion.
fox news showing weekly temperatures: 92, 92, 92, 94, 94, 92, 92, with a very strong gap between 94 and 92.
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Peter Kenny @pwk2024.bsky.social · 02/07/2026
The North of England (formerly Sheffield) #Cheminformatics Meeting will be held in Manchester from 21st to 23rd June 2027 #CompChem #chemsky 🧪 www.leachresearchgroup.net/home/chemoin...
leachresearchgroup.net
Andrew Leach Group - Chemoinformatics Conference 2027
Welcome to the new home of the North of England Chemoinformatics Meeting – formerly the Sheffield Chemoinformatics Meeting. This is a meeting of the Molecular Graphics and Modelling Society (MGMS: htt...
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Darren Fayne @fayned.bsky.social · 30/06/2026
This is a key driver of all research "Writing code, even hard code, has a rhythm to it. You are building. There is a thing in your head and you are making it real, and there is a quiet satisfaction in watching it take shape, and at the end there is something that is yours"
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Greg Landrum @greglandrum.bsky.social · 29/06/2026
“You can now set your availability in the reviewer dashboard to pause review invitations.” WTF? Do the journals think we work for them or something?
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Scott Bagley @bagphos.bsky.social · 27/06/2026
Reviewed a manuscript a couple months ago for a well known ACS journal Author posted on LinkedIn that the paper was published Never received comments/decision email from editor or any follow up Good paper glad it’s out but as a reviewer I’d have liked to see the comments/decision #ChemChat
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 29/06/2026
The manuscripts were neither retracted nor not-retracted, until you tried to read them…
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