Abstract. Like other cells, parasitic and other trypanosomatids sense Zn2+ and regulate Zn2+ transport, but the mechanisms involved remained unknown. Here,

Leishmania species are transmitted between mammals by sand flies, within which they undergo a complex developmental programme involving transitions between replicative and non-replicative life cycle f...

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Nature Communications - Here, Laidlaw, Garcia Sanchez and colleagues present a single-cell atlas for Trypanosoma cruzi, an important protozoan pathogen, providing insights into cell heterogeneity,...

An in vitro toolkit for studying VSG diversification defines key molecular requirements underlying the formation of mosaic VSGs, providing an experimental framework for the exploration of antigen diversification in Trypanosoma brucei and in other pathogenic microorganisms.

Nature Microbiology, Published online: 30 March 2026; doi:10.1038/s41564-026-02289-4To evade the immune system, Trypanosoma brucei relies on a specialized ‘expression site body’. Protein condensates within this nuclear compartment modulate expression of virulence genes via a targeted RNA decay mechanism.

To evade the immune system, Trypanosoma brucei relies on a specialized ‘expression site body’. Protein condensates within this nuclear compartment modulate expression of virulence genes via a targeted...

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