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Faria Tryps Lab

@fariatrypslab.bsky.social

265 followers 212 following 57 posts

The Faria Lab is based at University of York and studies nuclear architecture, genome organisation and biomolecular condensates in the context of gene expression regulation in trypanosomatids

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Faria Tryps Lab @fariatrypslab.bsky.social · 30/03/2026

(1/7) How does T. brucei achieve a 140-fold stoichiometric excess of VSG mRNA over upstream ESAGs from a single polycistronic unit? Our latest research in @natmicrobiol.nature.com reveals a mechanism of spatially regulated RNA decay to fine-tune expression of virulence genes

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Faria Tryps Lab @fariatrypslab.bsky.social · 28/01/2026

We’re hiring a PDRA and a technician! If you’re passionate about #parasites #genomes #condensates then this project is for you! Help us decode the role of nuclear architecture in gene expression regulation in #Leishmania alongside the @mottramlab.bsky.social @york.ac.uk @ybri-uoy.bsky.social

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Faria Tryps Lab @fariatrypslab.bsky.social · 11/08/2025

How do parasites strategically organise their genomes to influence gene expression? If you’re curious, check our latest review in @cp-trendsparasitol.bsky.social ! @biologyatyork.bsky.social @ybri-uoy.bsky.social @pasteur.fr www.sciencedirect.com/science/arti...

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Faria Tryps Lab @fariatrypslab.bsky.social · 27/05/2025

We identified 3 novel proteins at the ESB that negatively regulate genes co-transcribed with the active-VSG through specialised and spatially regulated RNA decay. #RNA #condensates #3Dgenome #RNAdecay

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Faria Tryps Lab @fariatrypslab.bsky.social · 31/03/2025

A bit late, but I fantastic time at @embl.org in Grenoble last week! Huge thanks to @kowaeva.bsky.social for the invitation and exciting discussions!

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Faria Tryps Lab @fariatrypslab.bsky.social · 16/01/2025

Are you interested in #trypanosomes #biomolecularcondensates and/or #geneexpression? We are looking for a highly motivated postdoc to work with with us in the beautiful city of York! Please share! jobs.york.ac.uk/vacancy/post...

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