iiinova — where your digital self keeps evolving

Edward Wallace @ewjwallace.bsky.social · 18h

Surely collagen and tendons also helping you keep together?

Edward Wallace @ewjwallace.bsky.social · 06/10/2026

When I set up the #RNAbiology list on bluesky, I didn't expect that it would gift all the weird things people say about ribosomes. Public engagement with science I guess?

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Edward Wallace @ewjwallace.bsky.social · 21/09/2026

Oh congratulations @markella-morait.bsky.social ! We will miss you in the Data Exploration in Biology course, where you have been a wonderful team member the last couple of years. Good luck with your next steps!

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The Endless Narf of the Waves @narfnra.bsky.social · 20/09/2026

it made me really happy when i learned that the way mutation ultimately creates new proteins is that it just randomly activates or inactivates parts of dna that start coding and your cellular machinery is like guess we makin 🟡 now. does 🟡 do anything. idk. guess we'll find out if we die

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Edward Wallace @ewjwallace.bsky.social · 09/09/2026

Ah, it's because the kids are alright and you occasionally get the warm glow of giving them useful advice that helps them move forward with their (scientific) lives. That's my optimistic take in a month where I'll be going to 8 committee meetings.

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Edward Wallace @ewjwallace.bsky.social · 19/08/2026

Postdoctoral position available! Help us to understand how fungi cause disease, by bringing data-driven engineering biology and cool fluorescent protein tools into fungal pathogens. Details: ewallace.github.io/news/postdoc... Please share!

ewallace.github.io

Postdoctoral position in fungal engineering biology

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Edward Wallace @ewjwallace.bsky.social · 19/08/2026

And will send you the MS when it's done.

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Edward Wallace @ewjwallace.bsky.social · 19/08/2026

Thank you so much @mcduncanlab.bsky.social! We should have put you as a reviewer - we're just revising the manuscript now for Yeast and will definitely add this reference.

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Edward Wallace @ewjwallace.bsky.social · 19/08/2026

Yeast colleagues: any idea what @zymoresearch.bsky.social do in their frozen yeast transformation kit for or instead of carrier DNA? zymoresearch.eu/products/fro... Kit looks great and is highly cited, I'm wondering about publicly available info ideally that I can cite in a review paper.

zymoresearch.eu

Frozen-EZ Yeast Transformation II Kit

Quickly and simply make competent yeast cells for highly efficient transformations.

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Edward Wallace @ewjwallace.bsky.social · 19/08/2026

Bunsen burners limitations in aseptic technique! Data-driven evidence here in a neat and careful study For what it's worth, the senior author Hannah Gavin is a lovely human who I used to occasionally play music with in Chicago.

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Edward Wallace @ewjwallace.bsky.social · 19/08/2026

The job will focus on developing a pan-fungal molecular bioimaging toolbox including fluorescent labelled fungal pathogen strains that can reveal previously hidden aspects of fungal biology. A good opportunity for an engineering biologist to move into medical mycology.

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Edward Wallace @ewjwallace.bsky.social · 19/08/2026

ewallace.github.io

Postdoctoral position in fungal engineering biology

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Edward Wallace @ewjwallace.bsky.social · 14/07/2026

Postdoc/staff scientist/ in computational biology and evolutionary genetics? Alex Cope is very good. I've collaborated with him for years. First author publications, all technically great, some in glam journals. A great team player and nice guy too. scholar.google.com/citations?us...

scholar.google.com

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Edward Wallace @ewjwallace.bsky.social · 17/08/2026

It's more that when I see a manuscript with mNG, mNeonGreen, NeonGreen, etc. used interchangeably I start to twitch. Also that all the mScarlet variants are difficult to keep track of (mScarlet, mScarlet-I, mScarletI-3, mScarlet 3-H) so have to be spelled out. I just use @fpbase.org

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Edward Wallace @ewjwallace.bsky.social · 14/07/2026

scholar.google.com

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Alex Cope, PhD (he/him) @alexcope241.bsky.social · 08/07/2026

If anyone is looking for a postdoc/staff scientist with experience in evolutionary genetics, computational biology/bioinformatics, and/or various omics methods (RNA-seq, Ribo-seq, LC-MS/MS), I'm still looking! (1) doi.org/10.1126/scie... (2) doi.org/10.1073/pnas... (3) doi.org/10.1371/jour...

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Shiv Grewal @grewalsh.bsky.social · 08/07/2026

Introns have a hidden regulatory role! 🧬🎉 Delighted to share our latest paper showing that inefficiently spliced introns and spliceosomal proteins direct RNA methylation, engaging RNAi to silence retrotransposons and regulate gene expression nature.com/articles/s41...

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Mara Duncan @mcduncanlab.bsky.social · 23/06/2026

Yes, I've done this. It's always a delight to work with SGD.

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Edward Wallace @ewjwallace.bsky.social · 24/06/2026

Where are we at on acceptable abbreviations for fluorescent proteins? Like, GFP for green fluorescent protein sure, but is mNG for mNeonGreen too much? Etc? Your strongest opinions and arguments invited.

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Edward Wallace @ewjwallace.bsky.social · 12/06/2026

What's the state of genomes that report on early animal / holozoan evolution? A student project in my lab on evolution of RNA-binding proteins is testing the hypothesis of a gene duplication in early metazoa, we want to look for homologs in in holozoa beyond Monosiga. @jlsteenwyk.bsky.social ?

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Edward Wallace @ewjwallace.bsky.social · 12/06/2026

Congratulations Robin, Becky, and team!

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Sophie Mason @sophiemason.bsky.social · 30/05/2026

I worked for UKRI for seven years and in my experience, the short timescales were 100% because of delays in central government. Usually because of delays in sign off by a minister; in the worst cases, due to number 10 comms teams insisting we hold back so the PM could announce it or whatever. 1/3

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IGMM-Montpellier @igmm-montpel.bsky.social · 05/05/2026

Save the date : Seminar by Edward Wallace from the University of Edinburgh on Tuesday 12th May at 11h @ewjwallace.bsky.social @edinburgh-uni.bsky.social

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Edward Wallace @ewjwallace.bsky.social · 29/04/2026

Look out for Domenico, whose next destination is a postdoc with @samreckpeterson.bsky.social ! The Reck-Peterson group's work on cargoes hitchhiking on endosomes, and their discovery of adaptors PxdA and DipA, inspired some of this story showing that mRNA-protein complexes also hitchhike.

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Edward Wallace @ewjwallace.bsky.social · 29/04/2026

The work is a tour-de-force from the PhD of @dmodaffari.bsky.social, co-supervised with Edinburgh colleague Ken Sawin. Domenico set up Aspergillus nidulans in the lab, did beautiful hypothesis-driven imaging experiments, and generally learned everything from everyone then did it even better.

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Edward Wallace @ewjwallace.bsky.social · 29/04/2026

How do fungi grow directionally? We think part of the mechanism involves local translation of mRNA near the tip, especially of cell wall components. Delighted to share our preprint showing that an RNA-binding protein, SsdA/Ssd1, is trafficked to the tip of growing fungal filaments.

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Edward Wallace @ewjwallace.bsky.social · 23/02/2026

I am learning a lot from this debate about the last eukaryotic common ancestor. It's thought-provoking to have competing hypotheses and perspectives argued out there in the open. Here, the two arguments are internally consistent, yet different conclusions... so where's the wrong assumption?

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Edward Wallace @ewjwallace.bsky.social · 23/02/2026

Today's @gautamdey.bsky.social seminar on Evolutionary Cell Biology is mind-blowing in so many ways. Dinoflagellates don't have histones!?!?! And BEAUTIFUL microscopy.

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The Daum Lab @daumlab.bsky.social · 15/01/2026

We are hiring a postdoctoral researcher to investigate ribosome hibernation and activation in microsporidia using confocal microscopy, soft X-ray tomography, cryo-electron tomography, and omics approaches. If you are interested, apply here: jobs.exeter.ac.uk/hrpr_webrecr...

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Evelina Tutucci @anilevetu.bsky.social · 10/01/2026

Happy to share that the our manuscript "Cyclin CLB2 mRNA localization and protein synthesis link cell cycle progression to bud growth" is now finally out in its final form @natcomms.nature.com www.nature.com/articles/s41... Below a short🧵 with the key findings!

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Edward Wallace @ewjwallace.bsky.social · 09/12/2025

Indeed it makes no sense and wastes a lot of peoples' time.

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Edward Wallace @ewjwallace.bsky.social · 09/12/2025

This. Named researcher positions do not have to be advertised.

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Edward Wallace @ewjwallace.bsky.social · 09/12/2025

Ok - sorry I misunderstood and glad the PI is on your side. IMO the PI could have dealt with it without worrying you. But the strategies that lots of us are suggesting are good. MRC writing a letter to HR, or, PI directly contacting a senior person in HR, also may help.

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Edward Wallace @ewjwallace.bsky.social · 09/12/2025

Yeah. The "PI said I didn't have to work any more on the project for now" gives a poor impression though.

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Edward Wallace @ewjwallace.bsky.social · 09/12/2025

IMO, after you've sought advice an appropriate next step could be a mediated meeting with the PI. Mediators could include an ethics officer, a union rep, HR person, or dept. chair. Take advice on how to prepare for the meeting to achieve your goals. 6/

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Edward Wallace @ewjwallace.bsky.social · 09/12/2025

More important advice: your department or institute should have a ethics office, ethics officer, or dean of research, who can advise you. The UK research integrity office has material on how to approach situations like this, and an email advice service. They may be able to help. ukrio.org 5/

ukrio.org

Home - UK Research Integrity Office

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Edward Wallace @ewjwallace.bsky.social · 09/12/2025

You're in the right so fighting is likely to get you *something* - maybe the job you fought for, maybe a payout. DOCUMENT EVERYTHING. I recommend the paper by CK Gunsalus, "How to blow the Whistle and still have a career afterwards." doi.org/10.1007/s119... Lastly, good luck. 4/

doi.org

How to blow the Whistle and still have a career afterwards - Science and Engineering Ethics

Filing charges of scientific misconduct can be a risky and dangerous endeavor. This article presents rules of conduct to follow when considering whether to report perceived misconduct, and a set of st...

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Edward Wallace @ewjwallace.bsky.social · 09/12/2025

You could also consider speaking to your local union representative, especially if you are a member. HR may be helpful. The MRC grants advisers may be helpful. However, in difficult situations like this if it can be resolved more locally that can be better. 3/

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Edward Wallace @ewjwallace.bsky.social · 09/12/2025

I recommend that you start by finding local senior folks who can take your corner. There should be a local "postdoc champion" or "postdoc advisor" who could help advocate for you. You may have another mentor or collaborator who can help. If you know the department chair, talk to them!!! 2/

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Edward Wallace @ewjwallace.bsky.social · 09/12/2025

Hi Maria. Sorry to hear about your situation. Your post is being shared around now as an example of "how others should not behave" and the situation reflects very badly on the PI. If you did this work for the grant and are named on it, you should be offered the job. You have some options 1/

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Edward Wallace @ewjwallace.bsky.social · 09/12/2025

This seems like you would have good advice for the original poster.

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