Unlike most solid-like tissues, immune tissue is protean and reconfigurable—its component cells can patrol vast territories, find rare cellular partners, and dynamically self-organize into functional ...

Since its February 2025 publication in Nature Cell Biology, a groundbreaking study from the Burnette Lab has drawn more than 44,000 Article Accesses—amplified by Vanderbilt’s new open access agreement...

Jeppesen, Sanchez et al. identify blebbisomes as large membrane-enclosed vesicles containing organelles and secreted by cells. Blebbisomes can both secrete and internalize exosomes and microvesicles.

This work identifies reactive oxygen species released by the electron transport chain as sentinel molecules that regulate localized protein degradation at mitochondrial TOM complexes, a mechanism that controls mitochondrial protein import and adjusts the abundance of the electron transport chain to cellular needs.

Modular synthetic G-protein-coupled receptors with nanobody-based ligand-recognition domains can be designed and used to programme transgene expression, real-time fluorescence or endogenous G-protein ...