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Emily Liman

@emilyliman.bsky.social
653 followers 146 following 25 posts

Professor of Neuroscience at USC (Los Angeles), #OTOP proton channels

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Reposted by Emily Liman
The Rockefeller University @rockefeller.edu · 22/09/2026
We are thrilled to announce that molecular biologist and neuroscientist Catherine Dulac of @harvardmcb.bsky.social is the 2026 winner of Rockefeller's Pearl Meister Greengard Prize! Register now for the award ceremony on Oct 20. #WomenInScience 🔗: bit.ly/3V2pZMA
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Erik A. Rodriguez @erin-rod.bsky.social · 21/08/2026
Today, I would like to honor the memory of Roger Y. Tsien, who died on August 24, 2016. His legacy lives with all who use his technologies, including calcium sensors, fluorescent proteins, the acetoxymethyl (AM) ester, & many more! #FluorescenceFriday www.nature.com/articles/nme...
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Drug Monkey @drugmonkey.bsky.social · 14/08/2026
Holy shit. “the final overall impact score or percentile on which the categorization was based would not be released to any of these parties. “
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Biophysical Society @biophysicalsoc.bsky.social · 14/08/2026
Biophysical Society is pleased to announce the results of our 2026 elections. buff.ly/afSFbFv
biophysics.org
Biophysical Society Announces the Results of its 2026 Elections
BETHESDA, MD – Vasanthi Jayaraman has been elected President-elect of the Biophysical Society (BPS). She will assume the office of President-elect at the 2027 BPS Annual Meeting in Philadelphia,…
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Ben Warner @bpw87544.bsky.social · 08/08/2026
Unfortunately the anti-education chuds don’t care about data They hate that the majority of college students are women, so they are devaluing college like they devalued other women dominated fields
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Physicians for a Healthy Democracy @physiciandemocracy.medsky.social · 05/08/2026
@catgyoung.bsky.social #medsky www.ovid.com/jnls/pidj/ab...
One of the largest US studies ever conducted on the MMR vaccine and autism has just been published, analyzing more than 2.5 million children.  Researchers found no association between receiving the first MMR vaccine before age 2 and childhood autism.
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Dr. Sven-Eric Jordt #TobRegSky @sejordt.bsky.social · 07/08/2026
#PedSky #MedSky #pulmsky #EpiSky #policysky #polisky #neuroskyence🛟🫁 "The Trump administration is considering an executive order on vaccines and autism that could be released as soon as next week"
reuters.com
Trump administration considers order on autism and vaccines, source says
The Trump administration is considering an executive order on vaccines and autism that could be released as soon as next week, a ​person familiar with the discussions said on Thursday.
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Coleen Murphy @ctmurphy1.bsky.social · 07/08/2026
I hadn't realized exactly how bad she would be
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Retraction Watch @retractionwatch.com · 23/07/2026
A couple paid more than $800,000 for a gene-editing therapy for their daughter. She died, and it wasn’t made public. An exclusive from us and @science.org.
science.org
Exclusive: Death of girl in Chinese gene-editing trial was never made public
Parents want accountability after study went disastrously wrong, Science and Retraction Watch investigation reveals
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Hugo Spiers @hugospiers.bsky.social · 19/07/2026
Brenda Milner is a hero and 108!! She did a lot more than discover the hippocampus is linked to declarative memory, but that work is the most famous.
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Mohammed Khallaf @khallaf.bsky.social · 15/07/2026
Our new paper is out in @nature.com! We uncovered how a naked mole-rat queen 👑 controls an entire colony: a natural contraceptive scent that suppresses reproduction in other females! A remarkable mammalian parallel to bees and ants! 🐝🐜 @garyrlewin.bsky.social youtu.be/enfv3zJrWKM?...
youtu.be
Naked mole-rats are ruled by a queen: this chemical puts her in power
YouTube video by nature video
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Ardem Patapoutian @ardemp.bskyverified.social · 24/06/2026
Please consider doing this!
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Emily Liman @emilyliman.bsky.social · 28/04/2026
Congratulations to all! A trifecta of amazing sensory biologists!
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Ardem Patapoutian @ardemp.bskyverified.social · 28/04/2026
Just got the news that Vanessa Ruta, Steve Liberles, and Uli Mueller are all elected to be members of the National Academy of Sciences @nasonline.org. All 3 are incredibly well-deserved. Congrats to all the new members! 🎉
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Jeremy Berg @jeremymberg.bsky.social · 02/04/2026
My quote of the day Space isn't remote at all. It's only an hour's drive away … if your car could go straight upwards. Fred Hoyle
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Emily Liman @emilyliman.bsky.social · 27/03/2026
Congratulations Alex (and Bob)! So well deserved!
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Ardem Patapoutian @ardemp.bskyverified.social · 05/03/2026
Congratulations to David Ginty and Patrik Ernfors for receiving The Brain Prize! 🎉👏 You can help David celebrate at this conference: www.janelia.org/you-janelia/...
janelia.org
No Brainer: Functional Mapping of the Peripheral Nervous System
Organizers Ardem Patapoutian, HHMI/Scripps Research Marissa Scavuzzo, Case Western Reserve University Stephen Liberles, HHMI/Harvard Medical School Invited Participants Ishmail Abdus-Saboor,
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Eric Mulhall @ericmulhall.bsky.social · 05/03/2026
Very excited to share our new manuscript – published today! Why are PIEZO1 and PIEZO2 are tuned to transduce different types of mechanical force? I was lucky to work with some extraordinary colleagues to begin to figure out why. www.nature.com/articles/s41... An overview of the results below ⬇️ ⬇️
nature.com
The molecular basis of force selectivity by PIEZO2 - Nature
PIEZO2 is intrinsically more rigid than PIEZO1, and disparate mechanical stimuli paradoxically evoke opposite conformational and gating responses in each channel.
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Rose Z. Hill, Ph.D. @rose-hill.bsky.social · 04/03/2026
So proud of my lab mate @ericmulhall.bsky.social and honored to help with this amazing project he led using MINFLUX to study why PIEZO2 behaves differently than PIEZO1 from the lab of @ardemp.bskyverified.social share.google/2Uln5O5OyqhM...
share.google
The molecular basis of force selectivity by PIEZO2 - Nature
PIEZO2 is intrinsically more rigid than PIEZO1, and disparate mechanical stimuli paradoxically evoke opposite conformational and gating responses in each channel.
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Reposted by Emily Liman
Jill Rosenthal @jillrose.bsky.social · 25/02/2026
This is the SAVE Act that Trump is discussing tonight.
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Emily Liman @emilyliman.bsky.social · 22/02/2026
Bye for now! Enjoy your offline sabbatical, and feel free to reach out by other avenues...
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Princess Vimentin PhD | Cancer Biologist @princess-vimentin.bsky.social · 08/02/2026
Rita Levi-Montalcini was raised by a strict father who disapproved of women in higher ed. She convinced him to let her study medicine. She went on to co-discover the Nerve Growth Factor. She received the Nobel Prize in 1986. She was another immigrant that gifted the US with pioneering work. 🧪

"I realised that I could not possibly adjust to a feminine role as conceived by my father"
RITA LEVI-MONTALCINI
Nobel Prize in Physiology or Medicine 1986


Born in Turin, Italy, in 1909, Rita Levi-Montalcini was raised by an authoritarian father who strongly disapproved of women's education beyond finishing school. His attitude was both a hindrance and a spur to Levi-Montalcini's ambitions.
She convinced him to let her study medicine.
Woefully undereducated to that point, she crammed years' worth of Greek, Latin and mathematics into eight months, and then entered medical school at the University of Turin.
Levi-Montalcini went on to become a neuroembryologist who co-discovered nerve growth factor, a prominent figure in Italian politics, and an active researcher and mentor until her death at the age of 103.
In 1986 she was awarded the medicine prize.
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Sarah Ross @sarahross1.bsky.social · 06/02/2026
I’ve never met anyone that would be better for this job. We need more scientists in congress!
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Ardem Patapoutian @ardemp.bskyverified.social · 06/02/2026
Excited to co-host this conference with @marissascavuzzo.bsky.social and Steve Liberles focused on the peripheral nervous system -- No Brainer! Check out the amazing list of speakers and apply for one of the spots for this small, interactive meeting on the beautiful Janelia Campus at HHMI.
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Sam Wang @samwang.bsky.social · 04/02/2026
News from central Jersey: I'm running to represent New Jersey's 12th Congressional District. By entering the fray, I hope to bring ideas of repairing our frayed republic. Not only to defend it in 2026, but to build something stronger, for generations to come! samwang.substack.com/p/entering-t...
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Jeremy Berg @jeremymberg.bsky.social · 14/01/2026
The appropriations bill that includes NIH is being finalized. The Senate bill includes a bipartisan amendment from Senators Capito (WV) and Baldwin (WI) limiting multi-year funding of grants. The House version does not and OMB has issued a veto threat if the House includes such language. 1/3
media.tenor.com
a close up of a brown surface with a few spots
ALT: a close up of a brown surface with a few spots
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Colette Delawalla, PhD @cdelawalla.bsky.social · 14/01/2026
HEY WAKE UP. www.theguardian.com/us-news/2026...
theguardian.com
UPenn faculty condemn Trump administration’s demand for ‘lists of Jews’
Groups say EEOC demand for names and personal details echoes dark history and threatens safety and civil rights
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Science Magazine @science.org · 26/12/2025
Of the hundreds of millions of people living with IBS worldwide, about two-thirds are women. Now, researchers have identified a biological pathway in the guts of mice that may help explain this disproportionate toll—a finding that could one day lead to new treatments. scim.ag/3YD8H78
scim.ag
Why are women more likely to get irritable bowel syndrome? New study provides clues
Cells in the guts of female mice respond to estrogen by increasing pain signaling, researchers find
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Kara Marshall @karalmarshall.bsky.social · 15/12/2025
When overwhelmed by scope of tragedy, specifics can be important. Here is just one story. Thinking of all those affected by this weekend's tragedies at Brown and in Sydney.
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Emily Liman @emilyliman.bsky.social · 15/12/2025
Thanks for sharing. Heartbreaking - and so senseless.
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Christie Wilcox @nerdychristie.bsky.social · 08/12/2025
Axolotls are famous for regenerating limbs. Turns out they can also regenerate their thymus—and that may show us how to someday to the same. That story and more of the best from @science.org and science in this edition of #ScienceAdviser: www.science.org/content/arti... 🧪
media.tenor.com
a close up of a white axolotl with pink ears standing on a rock .
ALT: a close up of a white axolotl with pink ears standing on a rock .
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Emily Liman @emilyliman.bsky.social · 29/11/2025
Congratulations! Check it out - very cool work! (and beautiful image!).
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Ardem Patapoutian @ardemp.bskyverified.social · 25/11/2025
Great story by @carlzimmer.com in @nytimes.com that nicely conveys the excitement for the emerging field of interoception. @dulaclab.bsky.social and others are featured, including my tattoo 😳! Gift article link: www.nytimes.com/2025/11/25/s...
nytimes.com
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Miriam B. Goodman, PhD @wormsense.bsky.social · 24/11/2025
Application review launches on December 1, 2025. We want to read *your* application outlining a vision for a research program deciphering how membrane proteins collaborate to enable cell function, their biosynthesis, and the biophysics and structure of how membrane proteins change shape.
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Steve Ramirez @okaysteve.bsky.social · 08/09/2025
Good morning everyone! So, I wrote a book (!!) and it’s coming out November 4th in physical and audiobook form. It’s called *How to Change a Memory* www.amazon.com/How-Change-M...
amazon.com
How to Change a Memory: One Neuroscientist’s Quest to Alter the Past
Buy How to Change a Memory: One Neuroscientist’s Quest to Alter the Past on Amazon.com ✓ FREE SHIPPING on qualified orders
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Jonathan Howard @joho.bsky.social · 21/11/2025
Bhattacharya's newest 1-page pandemic plan forcefully rejects the GBD, his previous 1-page pandemic plan. It's really just an admission that he's not competent enough to control a virus and not caring enough to even try. My latest devastating takedown. sciencebasedmedicine.org/bhattacharya...
sciencebasedmedicine.org
Goodbye to Focused Protection. Jay Bhattacharya’s Latest 1-Page Pandemic “Plan” is for Vulnerable People to Stop Being Vulnerable.
Jay Bhattacharya's new "plan" is really an admission that if there's a new pandemic, he’s not competent enough to do any of the incredible things he “would have” done regarding COVID. He's not
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turrigiano.bsky.social @turrigiano.bsky.social · 20/11/2025
Re-upping this - Neuropeeps! We have a TT Job in my wonderful department at Brandeis! First consideration to applications received by Dec 15 (but why wait?) www.nature.com/naturecareer...
nature.com
Assistant Professor in Biology and Neuroscience Program - Waltham, Massachusetts (US) job with Brandeis University | 12848464
The Department of Biology and the Program in Neuroscience at Brandeis University invite applications for a tenure-track Assistant Professor positio...
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Jacopo Razzauti @jacoporazzauti.bsky.social · 19/11/2025
Our preprint is out! www.biorxiv.org/content/10.1... Peter Skovorodnikov and I are excited to present FERAL: a new video-understanding toolkit that maps raw video directly to behavior, no pose estimation required. It works across species, from lab to field, and even in collective systems. (🧵1/n)
biorxiv.org
FERAL: A Video-Understanding System for Direct Video-to-Behavior Mapping
Animal behavior unfolds continuously in time, yet quantitative analyses often require segmenting it into discrete, interpretable states. Although manual annotation can achieve this, it remains slow, s...
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Ardem Patapoutian @ardemp.bskyverified.social · 11/11/2025
"Even Nobel Prize Winners Deal With Imposter Syndrome": Check this out @scifri.bsky.social: www.sciencefriday.com/segments/ard...
sciencefriday.com
Even Nobel Prize Winners Deal With Imposter Syndrome
Neuroscientist Ardem Patapoutian immigrated to the US, found belonging in science, and did groundbreaking work on sense of touch.
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Admirable Women @admirablewomen.bsky.social · 10/11/2025
Dr. Florence Sabin | Immunologist and educator, born #OTD in 1871. The first woman to hold a full professorship at Johns Hopkins School of Medicine (where she graduated from in 1900) and the first woman elected to the National Academy of Sciences. #WomenInSTEM
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Science Magazine @science.org · 08/11/2025
When asked to draw a scientist, school-age kids in the United States are increasingly sketching women, according to a study from 2018. Read more on #STEMSTEAMDay: scim.ag/4qFrPON
A child's drawing of a female scientist, with the text: What does a scientist look like? Children are drawing women more than ever before
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Cornelius Gati @gati.bsky.social · 05/11/2025
Excited to share our latest @nature.com: How does naloxone (Narcan) stop an opioid overdose? We determined the first GDP-bound μ-opioid receptor–G protein structures and found naloxone traps a novel "latent” state, preventing GDP release and G protein activation.💊🧪 🧵👇 www.nature.com/articles/s41...
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Michael Clemens @mclem.org · 01/11/2025
The United States was the leading destination for top scientists from all over the world. That is ending. Politicians ended it. It will cripple our future competitiveness. And it’s such a bitter tragedy. Almost no Americans, Conservative or Liberal, grasp what is now being stolen from them.
youtu.be
Top researchers consider leaving U.S. amid funding cuts: 'The science world is ending'
YouTube video by PBS NewsHour
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Emily Liman @emilyliman.bsky.social · 23/10/2025
Thank you!
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Emily Liman @emilyliman.bsky.social · 23/10/2025
Plot twist - CryoEM reveals that inhibitors bind to a different site (actually two sites). May displace cholesterol? The discovery of a druggable site will enable the identification of inhibitors and activators of other OTOP channels and propel research into their diverse physiological functions.
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Emily Liman @emilyliman.bsky.social · 23/10/2025
2x screens -> good, high affinity inhibitors.
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Emily Liman @emilyliman.bsky.social · 23/10/2025
Excited to report the identification of small molecule inhibitors of OTOP1 and their binding sites. Congratulations to first authors Batuuji Burendei from Ward/Forli labs at TSRI and Josh Kaplan for great team work! rdcu.be/eMpV9
rdcu.be
Structure-guided discovery of Otopetrin 1 inhibitors reveals druggable binding sites at the intrasubunit interface
Nature Communications - Otopetrins form proton channels in animals ranging from nematodes to humans. Here, authors identify small molecule inhibitors and characterize their binding in the...
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Frances Separovic @francesbiophys.bsky.social · 16/10/2025
Maud Menten was born in Canada in 1879 and completed her UG and MD education at University of Toronto. As a research assistant with Leonor Michaelis in 1912, they wrote the classic paper describing the “Michaelis-Menten” model of enzyme kinetics.. #WomenInScience
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Emily Liman @emilyliman.bsky.social · 16/10/2025
The hypothesis (combinatorial coding) didn't win the Nobel prize - the discovery of odorant receptors (by Linda Buck and Richard Axel) won it. It enabled the work touted by Science as well as a whole field of research.
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Emily Liman @emilyliman.bsky.social · 16/10/2025
Interesting. So, of course, I had to try it. It doesn't taste sour to me, tastes metallic. Anyone else try it? If it generates protons could activate OTOP1 proton channels in sour cells. But more likely sour cells are easier to activate with electrical stimulus.
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