iiinova — where your digital self keeps evolving

Enrico Carlon @ecarlon.bsky.social · 23/09/2026

This week I’m in Cargèse, Corsica, for the Transport in Narrow Channels workshop (21–25 Sept). Great science, stimulating discussions, a round table on AI and physics, and a magnificent setting! 🌊☀️ #Physics #SoftMatter #Biophysics

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Enrico Carlon @ecarlon.bsky.social · 18/09/2026

Congratulations to Midas Segers on successfully defending his PhD! 🎓 His thesis, “Multiscale Modeling of DNA: From Base Pairs to Chromosomes”, explores DNA mechanics and chromosome organization across scales, from base pairs to entire chromosomes. #DNAMechanics #Chromatin #Biophysics #KULeuven

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Enrico Carlon @ecarlon.bsky.social · 18/09/2026

🔬 Physics of Life Seminar | KU Leuven Prof. Édgar Roldán (ICTP, Trieste) “Non-equilibrium aspects of active mechanosensory cells: bullfrogs’ hair-cell bundles” 📅 Monday, Sept. 21 | 🕒 3pm | 📍 Dept. of Physics and Astronomy 05.34 @pol-kuleuven.bsky.social #PhysicsOfLife #Biophysics #KULeuven

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Enrico Carlon @ecarlon.bsky.social · 14/05/2026

Many thanks to Raymond Goldstein for a truly engaging two-day visit at @kuleuvenuniversity.bsky.social during which he presented a faculty colloquium on “Fluid Dynamics and the Evolution of Biological Complexity” and a seminar on “Decision-making without a brain.” @pol-kuleuven.bsky.social

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Enrico Carlon @ecarlon.bsky.social · 21/04/2026

The KULeuven Department of Physics and Astronomy is recruiting a new faculty member as Research Professor in Experimental Biophysics. The candidate is expected to develop and apply innovative experimental techniques to study the structure and behavior of living systems from a physics perspective.

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Enrico Carlon @ecarlon.bsky.social · 07/04/2026

🏅 2026 IUPAP Medal for the Physics of Life The International Union of Pure and Applied Physics (IUPAP), through its Commission on Biological Physics (C6), is pleased to announce that Dr. Uri Alon is the recipient of the 2026 IUPAP Medal for the Physics of Life iupap.org/who-we-are/i...

iupap.org

C6: News - IUPAP: The International Union of Pure and Applied Physics

2026 IUPAP Medal for the Physics of LifeDr. Uri AlonThe pioneering research by Dr. Alon laid the foundation for the field of Systems Biology. His contributions have shaped the conceptual framework of ...

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Enrico Carlon @ecarlon.bsky.social · 08/02/2026

If you’re in the London area, don’t miss this seminar at Kings College Tomorrow, Monday 9 Feb. at 12:30 "DNA topology: from DNA supercoiling to the organization of interphase chromosomes" by Midas Segers presenting recent work from our KU Leuven group mathsbiscuit.uk/dhd/maths.ev... #chromatin

mathsbiscuit.uk

Maths Events - Events in mathematics department of KCL

Maths Events is a collection of all talks, journal clubs, conferences and other research related events in the Mathematics Department of KCL.

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Marnie Blewitt @marnieblewitt.bsky.social · 06/02/2026

Our new preprint on SMCHD1! We’ve shown SMCHD1’s ATPase activity is critical for function in vivo, and excitingly a new DNA binding domain neighbouring the ATPase domain activates the enzymatic function, which is important for normal chromatin binding. urldefense.com/v3/__https:/...

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Sabina Caneva @sabinacaneva.bsky.social · 06/02/2026

💡 We are hiring! #PhD position in #Nanotechnology exploring DNA origami nanoactuators for molecular diagnostics 🧬 Apply here 👉 tinyurl.com/yc3a2cs7

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Enrico Carlon @ecarlon.bsky.social · 03/02/2026

KU Leuven awards an honorary doctorate to physicist Raymond E. Goldstein in recognition of his groundbreaking contributions to the Physics of Life, a field that uncovers the fundamental physical principles shaping living systems youtu.be/qQXnUPU2iAU

youtu.be

Raymond Goldstein | KU Leuven eredoctores 2026

YouTube video by KU Leuven

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Enrico Carlon @ecarlon.bsky.social · 20/01/2026

The 2024 Physics Nobel Prize is often portrayed as a "prize for AI". In this article I explain the connection with Physics. It is a translation of an article appeared in dutch in www.tijdschriftkarakter.be - @karakterasl.bsky.social ecarlon.wordpress.com/2025/12/09/p...

ecarlon.wordpress.com

Physics meets Computer Science: The 2024 Physics Nobel Prize

The 2024 Nobel Prize in Physics is often portrayed in the media as a recognition of artificial intelligence, making the link with Physics unclear to many. In this article I try to explain the conne…

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Enrico Carlon @ecarlon.bsky.social · 02/12/2025

If you happen to be in Seoul tomorrow Dec. 3 don't miss this seminar at the Korea Institute for Advanced Study (KIAS) "Chromatin structure from high resolution microscopy: Scaling laws and microphase separation" by Midas Segers (KU Leuven) www.kias.re.kr/kias/activit...

kias.re.kr

Seminars | Activities | KIAS(Korea Institute For Advanced Study)

85 Hoegi-ro, Dongdaemun-gu, Seoul 02455, Republic of Korea.

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Bussi Lab @bussilab.org · 28/11/2025

🎉Our group has been awarded a prestigious #FIS grant! #RNAScale - Exploring RNA Dynamics across Scales: From Base Pairs to Viral Genomes 👉 www.bussilab.org/fis3 We will soon open postdoctoral positions across several components of the project! An expression-of-interest form is already online.

bussilab.org

RNAScale

Exploring RNA Dynamics across Scales

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Enrico Carlon @ecarlon.bsky.social · 04/11/2025

Congratulations to Giandomenico Vanore on being awarded a PhD Fellowship by @fwovlaanderen.bsky.social He will conduct his doctoral research under my supervision on the project “Understanding the structure of interphase chromosomes.” #statistical_physics #polymers #chromatin #MD_simulations

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Physics of Life Leuven @pol-kuleuven.bsky.social · 08/10/2025

Working on biosensors? Don’t miss this MDPI webinar introducing thermal biosensing via the heat-transfer method (HTM) — a simple yet powerful way to detect biomolecular interactions and monitor cells. Pioneers of HTM will share their insights! #Biosensors #HTM More info: sciforum.net/event/Sensor...

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Enrico Carlon @ecarlon.bsky.social · 14/10/2025

🧬 Seminar Alert! Join us next Friday 17 Oct. for “Mechanics, Dynamics and Shape in Oocytes” by Dr. Bart Vos — a deep dive into how physical forces and cell mechanics shape early development. Discover the emerging field of mechanobiology, where physics meets life.

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Enrico Carlon @ecarlon.bsky.social · 14/10/2025

Interest in pursuing a PhD/postdoctoral position in experimental Condensed Matter Physics with applications to biological systems? Don’t miss this opportunity from the "Small Biosystems Lab" felixritortlab.com UBarcelona which combines statistical physics with single-molecule experimental techniques

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Enrico Carlon @ecarlon.bsky.social · 12/10/2025

New preprint! With Takahiro Sakaue we studied an active polymer dynamics focusing on the mean-square displacement of a monomer. We show that the MSD can be described by a simple compounding formula linking an isolated monomer MSD with tension propagation along the chain - arxiv.org/abs/2510.07949

arxiv.org

Compounding formula approach to chromatin and active polymer dynamics

Active polymers are ubiquitous in nature, and often kicked by persistent noises that break detailed balance. In order to capture the out-of-equilibrium dynamics of such active polymers, we propose a s...

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Enrico Carlon @ecarlon.bsky.social · 10/10/2025

Traveling back after an exciting three days meeting of the MeChaNiSM Doctoral Network @mechanism-network.bsky.social - Thanks to all students, PIs and supporting staff for these intense days of scientific discussions about our projects on DNA/RNA mechanics. www.chalmers.se/en/projects/...

chalmers.se

MeChaNiSM

Mechanical Characterization of Nucleic acids using Single Molecule techniques

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Condensed Matter Physics Center (IFIMAC) @ifimacuam.bsky.social · 04/09/2025

📢Seminar 11 September at 12h, Faculty of Science, Seminar Room Module 5 @cienciasuam.bsky.social @uam.es Enrico Carlon @ecarlon.bsky.social from KU Leuven will talk about DNA mechanics beyond the twistable wormlike chain. See you there! ifimac.uam.es/ifimac-semin...

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Cees Dekker @ceesdekker.bsky.social · 22/08/2025

Applicants wanted 5: Open position for PhD Student Studying Vitro Single-molecule Transport Across Peroxisome Mimics careers.tudelft.nl/job/Delft-Ph...

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Enrico Carlon @ecarlon.bsky.social · 22/08/2025

Interesting paper by Tony Lemos and Harold Kim. DNA minicircles adopt a specific inside-out orientation. Previously predicted, now this effect has been observed in atomic force microscopy (AFM) experiments! arxiv.org/abs/2508.15091

arxiv.org

Visualizing Poloidal Orientation in DNA Minicircles

A short (<150 bp) double-stranded DNA (dsDNA) molecule ligated end-to-end forms a DNA minicircle. Due to sequence-dependent, nonuniform bending energetics, such a minicircle is predicted to adopt a ce...

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Enrico Carlon @ecarlon.bsky.social · 21/07/2025

Enjoying this workshop on the Statistical Mechanics of polymers in Venice these days... Great program and organization! userswww.pd.infn.it/~orlandin/Ve...

Palazzo Franchetti. Istituto Veneto di Scienze, Lettere ed Arti

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Enrico Carlon @ecarlon.bsky.social · 22/04/2025

Very happy that our latest publication "Statistical mechanics of multiplectoneme phases in DNA" doi.org/10.1103/Phys... was selected as Editors' Suggestion. These suggestions list "a small number of papers that the editors and referees find of particular interest, importance, or clarity". (1/4)

doi.org

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Physics of Life Leuven @pol-kuleuven.bsky.social · 03/04/2025

Exciting news! PoL@KUL invites you to the inaugural lecture of the International Francqui Professor 2024-25, Prof. Davide Marenduzzo (U. of Edinburgh) on Tuesday, April 29, 2025 in Leuven: Biophysical principles of chromosome organisation Info and registration: fys.kuleuven.be/english/coll...

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Enrico Carlon @ecarlon.bsky.social · 31/03/2025

Welcome to Arianna Fassino who has recently joined our group to start a PhD project on simulations of Nucleic Acids Mechanics. The project is part of a EU-Marie Skłodowska Curie Doctoral Network “MeChaNiSM” Mechanical Characterization of Nucleic acids - www.chalmers.se/en/projects/...

chalmers.se

MeChaNiSM

Mechanical Characterization of Nucleic acids using Single Molecule techniques

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Biozentrum, University of Basel @biozentrum.unibas.ch · 20/03/2025

Apply now for our international Master of Science in Physics of Life @biozentrum.unibas.ch @unibasel.ch! Scholarships available. More information: www.biozentrum.unibas.ch/education/de... #Master #Students #Research #Physics #Mathematics #ComputerScience #Engineering #Basel #Switzerland

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Honsworth @drhonsworth.bsky.social · 18/03/2025

Very pleased to share our new story on SMC complexes, a great team effort from @roisnehamelinf.bsky.social, @taschner.bsky.social in the GruberLab and James of @dnatopologylab.bsky.social We find that SMC hinge domains are ssDNA gates to facilitate obstacle bypass during DNA loop extrusion!

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Stephan Gruber @gruberlab.bsky.social · 18/03/2025

Now, 20+ years later, our lab revisits the hinge using the anti-plasmid SMC complex Wadjet. We show that the SMC hinge is a DNA gate—an obstacle bypass gate selective for ssDNA, used to navigate chromosomal barriers during DNA loop extrusion.

schematic model for obstacle navigation by SMC rings by extrusion through the SMC lumen and by hinge bypassing

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Stephan Gruber @gruberlab.bsky.social · 18/03/2025

Yet another preprint from the lab—this one is personal. During my PhD, I ended up working on the cohesin SMC hinge, showing its role in sister chromatid cohesion and proposing it as a DNA entry gate in the SMC ring. But the details have remained mysterious and controversial.

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Stephan Gruber @gruberlab.bsky.social · 18/03/2025

Hinge bypass can explain some otherwise-difficult to explain observations made by colleagues using single molecule imaging and by simulating chromosome folding. DNA loop-extruding SMC complexes turn out to be even a bit more wonderful.

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Kazuhiro Maeshima @kazu-maeshima.bsky.social · 20/02/2025

Our new review on how the #chromatin domain is formed in the cell is now available @Curr Opin Struct Biol.📄✨ We critically discuss the domain formation mechanism from a physical perspective, including #phase-separation and #condensation. 📥 Free-download link: authors.elsevier.com/a/1keGn,LqAr...

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Rosana Collepardo @rcollepardo.bsky.social · 24/12/2024

Is chromatin ordered or disordered? It all depends on the linker DNA length. Check our latest work with Mike Rosen and Sy Redding. We explore how changes in linker DNA length (as small as 1 bp) fine-tune chromatin structure, between order and disorder, and the properties of chromatin droplets

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Enrico Carlon @ecarlon.bsky.social · 20/12/2024

Congratulations to Dr. Aderik Voorspoels on earning your PhD at KU Leuven! It was a honor to co-supervise your PhD journey. I am proud of all that you have accomplished and excited to see what the future holds for you. Wishing you every success for your post-doc at the University of Liverpool!

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Roman Barth @romanbarth.bsky.social · 16/12/2024

My first post! Hi science community 👋🧬 We have been trying to figure out the mechanistic mysteries about SMC motor proteins. They extrude our genome constantly into loops. We know that that's important. But how it works, is a matter of intense debate! Today, we report a piece of the puzzle:

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Tobias Warnecke @tobiaswarnecke.bsky.social · 16/12/2024

Please RT: Associate Professor position in my department at the University of Oxford. Broad search in molecular and cellular biology: my.corehr.com/pls/uoxrecru...

my.corehr.com

Job Details

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Enrico Carlon @ecarlon.bsky.social · 17/12/2024

A bit more than two weeks to apply for a PhD position in our group (deadline 1/1/2025) as part of a EU-Marie Skłodowska Curie Doctoral Network “MeChaNiSM”. www.kuleuven.be/personeel/jo... Please repost!

kuleuven.be

Simulations of Nucleic Acids Mechanics

Computer Simulations of Mechanical Properties of Nucleic Acids

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Enrico Carlon @ecarlon.bsky.social · 04/12/2024

PhD position available in our group as part of a EU-Marie Skłodowska Curie Doctoral Network “MeChaNiSM”. World-leading academic laboratories in single-molecule biophysics, organic synthesis, molecular modeling and industrial partners to train 15 Doctoral Candidates. www.kuleuven.be/personeel/jo...

kuleuven.be

Simulations of Nucleic Acids Mechanics

Computer Simulations of Mechanical Properties of Nucleic Acids

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Enrico Carlon @ecarlon.bsky.social · 13/11/2024

My first post here on Bluesky (left X-Twitter for good): Happy to be at a meeting on "DNA supercoiling and Liquid-liquid Phase separation" in the beautiful Sète (Montpellier, France). Interesting talks, interesting people!

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arXiv bot (cond-mat) @krxiv-cond-mat.bsky.social · 31/10/2024

Statistical Mechanics of Multiplectoneme Phases in DNA arxiv.org/pdf/2410.23145 Midas Segers, Enrico Skoruppa, Helmut Schiessel, Enrico Carlon

arxiv.org

Statistical Mechanics of Multiplectoneme Phases in DNA

arXiv abstract link

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Paolo De Los Rios @paolodelosrios.bsky.social · 11/11/2024

First post here. I am interested in chaperone proteins: how do cells counteract/revert protein misfolding and aggregation? What are the physics principles that allow these machines to work? Are native proteins in the cell thermodynamically stable? 1/4

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