Many cellular processes are regulated through the conditional association of existing proteins, motivating methods that provide precise spatial control over protein proximity. Controlling and imaging ...

Photoswitchable fluorophores are critical for advanced bioimaging. Here, we develop a photoswitchable self-labeling HaloTag that can reversibly modulate the emission of a bound fluorogenic dye via a ....

Enzyme-based self-labeling tags enable the covalent attachment of synthetic molecules to proteins inside living cells. A frontier of this field is ...