iiinova — where your digital self keeps evolving

Davide Seruggia @dseruggia.bsky.social · 24/06/2026

Glad to see this out! Led by postdoc Ana Kutschat, we found that ARID5B, associated with leukemia predisposition, acts as a transcriptional repressor by recruiting HDACs on chromatin

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Reposted by Davide Seruggia

CeMM @cemm.oeaw.ac.at · 24/06/2026

🧬How inherited DNA changes contribute to childhood #leukemia A new study from CeMM Adjunct PI @dseruggia.bsky.social's group at @stanna-ccri.bsky.social reveals how ARID5B guides immune cell development & how its loss may raise B-cell leukemia risk ➡️ bit.ly/4xZO4CK 📄 bit.ly/43RSc9X

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CeMM @cemm.oeaw.ac.at · 21/04/2026

🧪The lab of @dseruggia.bsky.social's at @stanna-ccri.bsky.social explores gene regulation in pediatric #leukemia. “Most of what we learn in cancer research in adults does not apply to pediatric cancer,” he said at the 𝘞𝘪𝘦𝘯𝘦𝘳 𝘒𝘰𝘯𝘻𝘦𝘳𝘵𝘩𝘢𝘶𝘴. 👉 bit.ly/4dUbn9q

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CeMM @cemm.oeaw.ac.at · 20/04/2026

🧬 𝗔 𝗻𝗲𝘄 𝗮𝗽𝗽𝗿𝗼𝗮𝗰𝗵 𝘁𝗼 𝗳𝗶𝗴𝗵𝘁 𝗰𝗵𝗶𝗹𝗱𝗵𝗼𝗼𝗱 #𝗹𝗲𝘂𝗸𝗲𝗺𝗶𝗮 In a @natcomms.nature.com paper, researchers from @dseruggia.bsky.social's group at @stanna-ccri.bsky.social & CeMM show that collapsing the SAGA scaffold destabilizes & degrades KAT2A, stopping #AML cell growth. 🔗 bit.ly/484XvFv 📄 bit.ly/4cPghT5

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Marco Hein @marco.heinlab.org · 11/03/2026

I’m very happy to be part of our FWF “Emerging Fields” consortium! Together with @gekaragoz.bsky.social, @sebastianfalk.bsky.social and CCRI/CeMM/VetMedUni colleagues Eleni Tomazou, @dseruggia.bsky.social and @floriangrebien.bsky.social, we will study the ribosome code in pediatric cancers.

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Waggoner Lab @labwaggoner.bsky.social · 03/03/2026

Nucleotide-resolution mapping of regulatory elements via allelic readout of tiled base editing @natcomms.nature.com @dseruggia.bsky.social @lucapinello.bsky.social @danielevanbauer.bsky.social www.nature.com/articles/s41...

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Davide Seruggia @dseruggia.bsky.social · 26/02/2026

Happy to share our paper in collaboration with cancerbits.bsky.social. We used machine learning & ATAC-seq to refine erythroid differentiation protocols. Recipes for lineage differentiation are written on chromatin! @stanna-ccri.bsky.social @cemm.oeaw.ac.at

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Pauli Group (posts by Andi Pauli) @pauligroup.bsky.social · 03/01/2026

If you want to become an expert in #zebrafish research, apply for the 2026 Zebrafish Development & Genetics course! You will be working in small groups taught by leaders in the field, which can be a transformative experience! Application deadline: March 2 www.mbl.edu/education/ad...

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Reposted by Davide Seruggia

CeMM @cemm.oeaw.ac.at · 16/12/2025

📣 Join the @viennabiocenter.bsky.social #SummerSchool 2026! Check out the opening in CeMM Adjunct PI @dseruggia.bsky.social's lab & work on targeting chromatin regulators in leukemia. Find out more & apply now ➡️ bit.ly/4plpBmI

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Davide Seruggia @dseruggia.bsky.social · 09/09/2025

Join us for the second iteration of our yearly, St. Anna CCRI Symposium. This year, we will host experts in Cell Fate in Cancer and Development. Don't miss it!

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Davide Seruggia @dseruggia.bsky.social · 01/08/2025

⬇️ Our latest work on the #SAGA complex - see thread from @paulbatty1.bsky.social ⬇️

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Paul Batty @paulbatty1.bsky.social · 01/08/2025

I am pleased to share a new preprint from my postdoc in the @dseruggia.bsky.social lab. We discovered a structural dependency within the CORE module of the transcriptional coactivator SAGA, which regulates the stability of its histone acetyl transferase, KAT2A. www.biorxiv.org/content/10.1... 1/n

biorxiv.org

Disruption of the SAGA CORE triggers collateral degradation of KAT2A

The SAGA transcriptional co-activator complex regulates gene expression through histone acetylation at promoters, mediated by its histone acetyl transferase, KAT2A. While its structure and function ha...

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Davide Seruggia @dseruggia.bsky.social · 10/06/2025

This also reminds us what an emotional rollercoaster science can be! :)

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Davide Seruggia @dseruggia.bsky.social · 22/01/2025

In a couple of days at Van Swieten Saal in Vienna: join us for an immersive afternoon with six fantastic speakers, and learn more about #pediatric #cancer & #epigenetics.

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Elisa Manieri @e-manieri.bsky.social · 03/01/2025

📣Funded #PhDposition! – Pls RT! Looking for a passionate PhD student to explore cellular crosstalk in #TumorMicroenvironment combining #organoids #scRNAseq &high-res imaging. Join us @VetmeduniVienna in a vibrant research environment! #CancerResearch #PhD 👉 euraxess.ec.europa.eu/jobs/302158

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Davide Seruggia @dseruggia.bsky.social · 28/11/2024

Let's start with a group picture of the seruggialab.com 🐁🩸🧬 :)

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