ABSTRACTThe Indian Society for Assisted Reproduction (ISAR), Indian Fertility Society (IFS) and Academy of Clinical Embryologists (ACE) jointly...

भारतीय वैज्ञानिकों ने प्लेसेंटा-ऑन-ए-चिप तकनीक विकसित की है, जो प्रयोगशाला में इंसानी प्लेसेंटा के काम की नक़ल करती है. इससे गर्भावस्था में दवाओं की सुरक्षा, प्लेसेंटा से जुड़ी जटिलताओं और मां-बच्चे क...

ICMR and IIT Bombay researchers develop a platform that mimics key functions of the placenta and could help researchers understand how medicines, pollutants and infections reach the foetus without rel...

A functional placenta-on-chip model for maternal-fetal transport, Bhide, Anshul, Mukherjee, Sourav, Ghosh, Kinjalka, Majumder, Abhijit, Modi, Deepak

Journal of Assisted Reproduction and Genetics -

A Primer on Clinical Classification and Pathophysiology of Endometriosis

Endometriosis is recognized as a steroid hormone-dependent disorder. However, controversies exist regarding the status of the steroid hormone receptor expression in endometriotic tissues. The purpose of this study was to determine the ontogeny of ...

Analysis of data from pre-implantation genetic testing sheds light on the genetic basis of meiotic-origin aneuploidy, the leading cause of human pregnancy loss, identifying common genetic variants ass...

WHO regrets the United States’ notification of withdrawal from WHO – a decision that makes both the United States and the world less safe. The notification of withdrawal raises issues that will be con...

In briefA successful pregnancy begins with embryo implantation, but how the embryo breaks through the endometrial lining is not understood. Here, we uncove

Using temporarily spaced high-coverage ancient genomes, we can assess population decline prior to extinction. However, finding suitable ancient remains for recovering this type of data is challenging. Here, we sequenced a high-coverage genome from ...

In this review, Weichselberger, Moore et al. discuss how physics-based approaches illuminate organoid development and homeostasis by integrating mechanical, chemical, and informational processes. They...

Successful implantation requires tightly regulated endometrial inflammation. While initial inflammatory signaling is essential for implantation, persi…

A Nature analysis reveals the 25 highest-cited papers published this century and explores why they are breaking records.

Successful implantation requires precisely timed endometrial inflammation. Although an initial inflammatory burst is essential for implantation, this response must be rapidly resolved for placentation...

The molecular, cellular, and functional restoration of the axolotl thymus after de novo regeneration is described.

Wang et al. identify a new lytic cell death pathway, mitoxyperilysis, triggered by the synergy of innate immune activation and metabolic stress. This process is regulated by mTORC2 and involves persis...

Embryo implantation represents a critical bottleneck in human reproduction, and impaired endometrial receptivity is a major contributor to recurrent implantation failure (RIF) and infertility. Current...

Mumbai: City scientists have solved a long-standing mystery of how an embryo attaches itself to the wall of the womb: with a \"genetic switch\".For a pr.

Cell Death Discovery - HOXA10-TWIST2 antagonism drives partial epithelial-to-mesenchymal transition for embryo implantation

Purpose Y chromosome microdeletions (YCMD) are a common cause of azoospermia and oligozoospermia in men. Herein, we developed a machine learning-based web tool to predict sperm retrieval rates and suc...

Genome-wide analyses of 10 educational fields identify 17 associated loci. Analysis of genetic clustering across specializations identifies two key dimensions that show genetic overlap with personalit...