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Kevin Pruitt

@dr-kevin-pruitt.bsky.social
2.9K followers 699 following 827 posts

Associate Professor | UNC Chapel Hill, Pharmacology Department | Lineberger Comprehensive Cancer Center | Research in Endocrinology, Epigenetics, & Wnt signaling| Views my own. www.med.unc.edu/pharm/pruittlab/team

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Reposted by Kevin Pruitt
Kevin Pruitt @dr-kevin-pruitt.bsky.social · 08/09/2026
First mountain trail walk in a while. I love the land contours at a higher elevation and the ephemeral beauty of clouds rolling in. #Asheville
Photo of tree covered mountains lining the horizon as clouds roll in.

Asheville, North Carolina
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 08/09/2026
First mountain trail walk in a while. I love the land contours at a higher elevation and the ephemeral beauty of clouds rolling in. #Asheville
Photo of tree covered mountains lining the horizon as clouds roll in.

Asheville, North Carolina
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Reposted by Kevin Pruitt
UNC Microbiome Core @microbiomeunc.bsky.social · 25/08/2026
Join us for our First Friday Microbiome Seminar! 🦠 📅 Sept. 4 | 12 PM 📍 Marsico Hall 2004 + Zoom Hear from Andrea Azcarate-Peril on engineering microbial ecosystems and Aaron Koh on how S. pneumoniae may restrict influenza A infection. 🍕 Pizza provided!
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 27/04/2026
At our recent Translational Medicine symposium, Emma Armstrong, a student in my lab, won a best poster award. So excited for her and the progress we're making in identifying how oncogenic drivers suppress the immune system and evade detection in tumors.
Photo of student presenting a poster of her project that focuses on elucidating how novel drivers of immune suppression promote tumor progression. Participants are gathered to hear about the advances she's made. This was part of an annual Translational Medicine symposium held on the UNC Chapel Hill campus.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 27/04/2026
At our recent Translational Medicine symposium, Emma Armstrong, a student in my lab, won a best poster award. So excited for her and the progress we're making in identifying how oncogenic drivers suppress the immune system and evade detection in tumors.
Photo of student presenting a poster of her project that focuses on elucidating how novel drivers of immune suppression promote tumor progression. Participants are gathered to hear about the advances she's made. This was part of an annual Translational Medicine symposium held on the UNC Chapel Hill campus.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 14/03/2026
My student, Grace Stroman, was selected to present at the 9th Chromatin and Epigenetics Symposium. Her presentation was exceptional! Our keynote speaker @grewalsh.bsky.social was brilliant! Thanks to the organizers, @unclineberger.bsky.social, and @brianstrahl.bsky.social for a remarkable meeting!
Photo of Grace Stroman at podium prior to her presentation at UNC Chapel Hill. Her presentation focused on novel roles of MeCP2, DNA methylation reader which is a potent regulator of development. MeCP2 is most known for its cause of Rett Syndrome when mutated, but Grace is presenting some of the lab’s latest findings on the role of MeCP2 in cancer biology.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 14/03/2026
My student, Grace Stroman, was selected to present at the 9th Chromatin and Epigenetics Symposium. Her presentation was exceptional! Our keynote speaker @grewalsh.bsky.social was brilliant! Thanks to the organizers, @unclineberger.bsky.social, and @brianstrahl.bsky.social for a remarkable meeting!
Photo of Grace Stroman at podium prior to her presentation at UNC Chapel Hill. Her presentation focused on novel roles of MeCP2, DNA methylation reader which is a potent regulator of development. MeCP2 is most known for its cause of Rett Syndrome when mutated, but Grace is presenting some of the lab’s latest findings on the role of MeCP2 in cancer biology.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 13/03/2026
Signs of the advent of spring outside of @unclineberger.bsky.social #photography #UNC
Trees outside of Lineberger Cancer Center on the campus of UNC Chapel Hill on a chilly but beautiful sunny morning.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 13/03/2026
Signs of the advent of spring outside of @unclineberger.bsky.social #photography #UNC
Trees outside of Lineberger Cancer Center on the campus of UNC Chapel Hill on a chilly but beautiful sunny morning.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 03/01/2026
Trailwalk before the cold and rain descended. #nature #forest #bluesky #photography #NorthCarolina
Photo of a trail with trees and a bluesky in the horizon.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 03/01/2026
Trailwalk before the cold and rain descended. #nature #forest #bluesky #photography #NorthCarolina
Photo of a trail with trees and a bluesky in the horizon.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 02/01/2026
On first trailwalk of the year, the trees also welcomed 2026. #January2026 #forest #trees #light #NorthCarolina
Path along a trail in a North Carolina forest. Rays of sun stream through trees on a peaceful January day.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 02/01/2026
On first trailwalk of the year, the trees also welcomed 2026. #January2026 #forest #trees #light #NorthCarolina
Path along a trail in a North Carolina forest. Rays of sun stream through trees on a peaceful January day.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 01/01/2026
Happy New Year Bluesky friends. May 2026 be kind to you and open new vistas of opportunity and fulfillment. 🎉🎈🎊 #2026 #NewBeginnings #NewYear #Restart
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 01/01/2026
Happy New Year Bluesky friends. May 2026 be kind to you and open new vistas of opportunity and fulfillment. 🎉🎈🎊 #2026 #NewBeginnings #NewYear #Restart
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 24/12/2025
What a lovely day for a trailwalk. #trailwalk #winter #bluesky #photography #light #bridge
Photo of bridge with trees and a bluesky in the horizon on a North Carolina trail.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 28/12/2025
Visited the North Carolina Museum of Art @ncartmuseum.bsky.social for the first time. So many breathtaking exhibits. #NCMA #Art #Museum #paintings #sculptures #photography
A few of the many phenomenal exhibits at the North Carolina Museum of Art
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 28/12/2025
Visited the North Carolina Museum of Art @ncartmuseum.bsky.social for the first time. So many breathtaking exhibits. #NCMA #Art #Museum #paintings #sculptures #photography
A few of the many phenomenal exhibits at the North Carolina Museum of Art
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 24/12/2025
What a lovely day for a trailwalk. #trailwalk #winter #bluesky #photography #light #bridge
Photo of bridge with trees and a bluesky in the horizon on a North Carolina trail.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 22/11/2025
Had an amazing visit to the NIEHS to present the lab's research. The depth of expertise in #epigenetics and chromatin biology there is remarkable. Big thanks to @jxhoffman.bsky.social for hosting me. 🧪
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 23/09/2025
Gave a seminar at the Van Andel Institute and greatly enjoyed meeting with pioneers in the field of Wnt signaling @sgraingerphd.bsky.social and @bartwilliams.bsky.social. Also reunited with amazing colleagues in the fields of epigenetics and RAS biology. What a vibrant research community @vai.org!
Photo of @dr-kevin-pruitt.bsky.social standing in front of slides from the podium where he gave a seminar at the Van Andel Institute.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 14/12/2025
Our first time going to see the musical comedy, Christmas Carole. Was amazing! #PerformingArts #BullCity #DPAC #Theatre
Photo of near stairway entrance and in balcony seats inside of the Durham Performing Arts Center in Durham, NC.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 14/12/2025
Our first time going to see the musical comedy, Christmas Carole. Was amazing! #PerformingArts #BullCity #DPAC #Theatre
Photo of near stairway entrance and in balcony seats inside of the Durham Performing Arts Center in Durham, NC.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 13/12/2025
The gifts given by nature in the winter are often fleeting, and can be easily missed. I received a few today. #peace #gratitude #perspective #balance
While enjoying first trailwalk of the season. I couldn't help but to capture how the winter trees and vines provide companionship to the stream and its chilly water. #trailwalk #photography
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 13/12/2025
The gifts given by nature in the winter are often fleeting, and can be easily missed. I received a few today. #peace #gratitude #perspective #balance
While enjoying first trailwalk of the season. I couldn't help but to capture how the winter trees and vines provide companionship to the stream and its chilly water. #trailwalk #photography
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Mary Munson @marymunson4.bsky.social · 06/12/2025
So grateful for the opportunity to work with this amazing ASCB team! #cellbio2025 #cellbio25
ASCB past-President, President-elect, current President (me) and interim CEO standing in front of the Cell Bio 25 sign!
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 16/07/2025
For years, we searched for factors which are dysregulated in cancer and regulate development. We now describe elusive roles of DVL, a protein co-opted in #cancer and mutated in congenital disorders thanks to lab members & support from @unclineberger.bsky.social & @unc-phco.bsky.social rdcu.be/ewwsZ
rdcu.be
Dishevelled-1 regulates global transcriptomic changes and associates with ETS1 transcription factor
Nature Communications - Currently, nuclear roles for DVL1 and its involvement in gene regulation remained unclear. Here the authors reveal that altering DVL1 expression significantly reshapes gene...
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Sarah Cohen @cohenlaboratory.bsky.social · 05/12/2025
Attending #CellBio2025? Come see the Cohen Lab - Monday will be a busy day for us, including my theatrical debut in WICB "Scripts of Success" skits!
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Tina Termini @cterminiphd.bsky.social · 05/12/2025
Say cheeeeese! Me and the current, future, and past Presidents of ASCB. Seeing is believing ♥️ 🧬 💗 📸 #CellBio2025 @marymunson4.bsky.social
A group of five women smiling as they pose for a photo together.
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Dalia Martinez-Marin @dalimartinez.bsky.social · 08/07/2025
And here it is! Our @natcomms.nature.com paper describing an exciting role of Dishevelled-1. 🔗: rdcu.be/evkf4 Such an amazing team of scientists, super excited to see where we go next! ❤️
rdcu.be
Dishevelled-1 regulates global transcriptomic changes and associates with ETS1 transcription factor
Nature Communications - Currently, nuclear roles for DVL1 and its involvement in gene regulation remained unclear. Here the authors reveal that altering DVL1 expression significantly reshapes gene...
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Jackson Hoffman @jxhoffman.bsky.social · 12/02/2025
Unpause! I'm super happy to now be able to share the published version of our paper at Science Advances showing that: 1) active histone mods occur independently of transcription 2) transcription coordinates histone deacetylation at active promoters www.science.org/doi/10.1126/...
science.org
RNA polymerase II coordinates histone deacetylation at active promoters
Transcription initiation limits histone acetylation and H2AZ incorporation at promoters.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 22/11/2025
Had an amazing visit to the NIEHS to present the lab's research. The depth of expertise in #epigenetics and chromatin biology there is remarkable. Big thanks to @jxhoffman.bsky.social for hosting me. 🧪
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The GW Cancer Center @gwcancercenter.bsky.social · 02/10/2025
Immense pride for the GW team (Chiappinelli, Seto & co.) pushing the frontier on cancer, immunity, and the dark genome. Their discoveries could revolutionize the treatment of stubborn tumors. Read the full piece — this is science with real hope. buff.ly/jTsiumZ #GWCancerCenter #Epigenetics
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 17/10/2025
This month we celebrated our 2nd yr since relocating to UNC and my final TTUHSC PhD defense of the talented Dr. Geetha Boligala, a thoughtful, creative, hard working, and brilliant lab member who's finalizing one of our most notable discoveries. She is simply amazing! @geethapboligala.bsky.social
Photo of advisor and newly minted PhD recipient after a successful defense standing in front of celebratory signs.
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Jean Cook (DNAtarheel) @dnatarheel.bsky.social · 30/09/2025
The link for a junior tenure-track position with UNC-CH Biochemistry and Biophysics is now live. Learn about the search here www.med.unc.edu/biochem/join..., then apply here unc.peopleadmin.com/postings/307... Help us inspire tomorrow’s discoveries by decoding the molecular basis of life!
med.unc.edu
UNC Department of Biochemistry and Biophysics
Our mission is to perform transformative biochemical and biophysical research in an inclusive and stimulating training environment.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 17/10/2025
This month we celebrated our 2nd yr since relocating to UNC and my final TTUHSC PhD defense of the talented Dr. Geetha Boligala, a thoughtful, creative, hard working, and brilliant lab member who's finalizing one of our most notable discoveries. She is simply amazing! @geethapboligala.bsky.social
Photo of advisor and newly minted PhD recipient after a successful defense standing in front of celebratory signs.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 03/10/2025
Congrats to Dr. Flavia Sardela de Miranda on her PhD defense! Smart, resilient, kind, hardworking, phenomenal lab member with amazing communication skills are just a few words that describe @flaviasardela.bsky.social. Your future is bright and you deserve the good coming your way. So proud of you!🎉
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 03/10/2025
Congrats to Dr. Flavia Sardela de Miranda on her PhD defense! Smart, resilient, kind, hardworking, phenomenal lab member with amazing communication skills are just a few words that describe @flaviasardela.bsky.social. Your future is bright and you deserve the good coming your way. So proud of you!🎉
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Dr. Donita C. Brady of Brady Lab UPenn @bradylabupenn.bsky.social · 27/09/2025
🚨 Our 4th example of metalloallosteric regulation of kinase activity. Out today in @CellReports with @KJSsci. The ER stress sensor kinase PERK needs copper to work. Without copper, PERK can’t protect cells under stress. cell.com/cell-reports/p…
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 23/09/2025
Gave a seminar at the Van Andel Institute and greatly enjoyed meeting with pioneers in the field of Wnt signaling @sgraingerphd.bsky.social and @bartwilliams.bsky.social. Also reunited with amazing colleagues in the fields of epigenetics and RAS biology. What a vibrant research community @vai.org!
Photo of @dr-kevin-pruitt.bsky.social standing in front of slides from the podium where he gave a seminar at the Van Andel Institute.
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Bryjalab @bryjalab.bsky.social · 13/09/2025
Big day for Bryjalab yesterday! Mirek Micka & Tomáš Gybeľ nailed their defences — welcome to the PhD club! 🎓🔥 Thanks to everyone who supported them along the way and came to celebrate! 🎉🤗
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Kristy Ainslie's Lab @kristy-ainslie-lab.bsky.social · 13/09/2025
Congrats Ryan Woodring on your 1st author pub "Biodegradable nanofibrous scaffolds enhance standard of care for glioblastoma via localized targeted therapy" Open Access: go.unc.edu/AinslieLabTMZ
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 10/09/2025
A moment from Day 1 of a symposium celebrating 50 yrs of discovery at UNC Lineberger Cancer Center. This talk by Dr. Edison Liu was one of many filled with inspiration and remarkable feats of scientific discovery. @unclineberger.bsky.social
A pic shared by Dr. Ed Liu in his early days at UNC Lineberger Cancer Center. Image is of him and members of his lab.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 10/09/2025
A moment from Day 1 of a symposium celebrating 50 yrs of discovery at UNC Lineberger Cancer Center. This talk by Dr. Edison Liu was one of many filled with inspiration and remarkable feats of scientific discovery. @unclineberger.bsky.social
A pic shared by Dr. Ed Liu in his early days at UNC Lineberger Cancer Center. Image is of him and members of his lab.
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UNC Lineberger Comprehensive Cancer Center @unclineberger.bsky.social · 09/09/2025
Big thank you to Cristy Page, MD, MPH, Interim CEO and Dean, UNC Health and UNC School of Medicine, for stopping by the UNC Lineberger scientific symposium to speak to the scientists, clinicians, and advocates in attendance. unclineberger.org/symposium/
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UNC Lineberger Comprehensive Cancer Center @unclineberger.bsky.social · 09/09/2025
We’re halfway through Day 1 of the UNC Lineberger Scientific Symposium, and what an inspiring morning it’s been! From powerful insights on cancer care, prevention, and biology—our speakers are delivering. Onsite registration is open, or join us virtually anytime: unclineberger.org/symposium/
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Brian Strahl @brianstrahl.bsky.social · 11/08/2025
Ever wondered what else SETD2 does beyond transcription? 🧬 Check out our new ‪@natcellbio.nature.com‬ study. Awesome work from Abid Khan in the lab SETD2 moonlights during mitosis to keep the genome safe from chaos.showing how SETD2 moonlights to safeguard the genome during cell division.
SETD2 moonlights during mitosis to keep the genome safe from chaos.https://www.nature.com/articles/s41556-025-01723-9
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 31/08/2025
Enjoyed cooler temps on a lovely morning walk. #bluesky #latesummer #peace #light #photography
Photo of a shaded path along a neighborhood side street as summer draws to a close.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 31/08/2025
Enjoyed cooler temps on a lovely morning walk. #bluesky #latesummer #peace #light #photography
Photo of a shaded path along a neighborhood side street as summer draws to a close.
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Kevin Pruitt @dr-kevin-pruitt.bsky.social · 27/07/2025
Welcomed the momentary peace of nature. #trailwalk #gratitude #nature #bluesky #photography #summer #calm #peace
Sun streaming through trees of different sizes displaying the glorious cycles of life.
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