Sign in

Deen Sun

@deensun3.bsky.social
98 followers 193 following 1 posts

Assistant professor at Peking U | Postdoc in Kai Johnsson Lab at MPIMR Heidelberg | Ph.D in Xing Chen Lab at Peking U | Chemical biology, Expansion🔬, Molecular probes scholar.google.co.kr/citations?user…

PostsRepliesMedia
Reposted by Deen Sun
Peng Wu @pengwu.bsky.social · 17/05/2026
This is the first @smartsymposium.bsky.social , Decoding the Glycome. We have lined up fantastic speakers, including experts in glycosylation and tool developers whose technologies hold exciting potential for applications in glycoscience. We look forward to welcoming you to Shenzhen this November
mp.weixin.qq.com
会议预告 | SMART Symposium:解码糖组—探索生物学未达之境
2026年11月16日-19日召开会议,2026年11月13日报名截止
0103
Reposted by Deen Sun
Leonhard Möckl @lmoeckl.bsky.social · 16/05/2026
Glycan Atlassing is online at @natnano.nature.com! Thanks to everyone involved, especially to @dijo-mj.bsky.social and @nazlicanyurekli.bsky.social who spearheaded the work. Read the paper here: dlvr.it/TSXNDb #Glycotime
dlvr.it
Glycan atlassing enables functional tracing of cell state - Nature Nanotechnology
Multiplexed super-resolution microscopy of DNA-barcoded lectins and metabolically incorporated unnatural sugars quantitatively links the nanoscale spatial relationships of glycocalyx organization and ...
0148
Reposted by Deen Sun
Kai Johnsson @kjohnsson.bsky.social · 22/04/2026
Localizable fluorescent metal ion indicators galore: advanced.onlinelibrary.wiley.com/doi/10.1002/...
advanced.onlinelibrary.wiley.com
Localizable Fluorescent Metal Ion Indicators With Tunable Colors
A modular platform enables the generation of fluorescent metal ion indicators with tunable emission colors and precise subcellular localization. Conjugation to self-labeling proteins yields bright, c...
0277
Reposted by Deen Sun
Kai Johnsson @kjohnsson.bsky.social · 26/03/2026
A high-affinity split-HaloTag for live-cell protein labeling. And much more. www.nature.com/articles/s41...
nature.com
A high-affinity split-HaloTag for live-cell protein labeling
Nature Communications - Lin and colleagues present high-affinity split-HaloTag pairs for protein tagging and multiplexed labelling. This versatile system allows protein visualisation with diverse...
213353
Reposted by Deen Sun
Kai Johnsson @kjohnsson.bsky.social · 08/03/2026
A Cinderella story: raising CLIP-tag from the ashes to shine in fluorescence labeling. www.biorxiv.org/content/10.6...
biorxiv.org
03214
Reposted by Deen Sun
Jin Zhang Lab @jinzhanglab.bsky.social · 13/02/2026
🚨🚨Double preprint alert! 🚨🚨 Two papers went up on Biorxiv this week! The first presents new chemigenetic FRET-based biosensors: www.biorxiv.org/content/10.6... And the second presents an improved version of our C-Y FRET PKA reporters, AKAR6 www.biorxiv.org/content/10.6... Thread 🧵 1/5
biorxiv.org
11410
Reposted by Deen Sun
Kai Johnsson @kjohnsson.bsky.social · 31/12/2025
A good end to 2025: rhodamine-binders for bioimaging in JACS: pubs.acs.org/doi/10.1021/...
pubs.acs.org
Fast, Bright, and Reversible Fluorescent Labeling of Rhodamine-Binding Proteins
Rhodamine dyes conjugated to targeting ligands can yield exceptionally bright fluorescent probes for live-cell imaging. However, the limited permeability of such rhodamine derivatives restricts their ...
0277
Deen Sun @deensun3.bsky.social · 08/12/2025
🚨Excited to share this collaborative work with Ming-Ming. 🎉Check it out!▶️https://www.biorxiv.org/content/10.64898/2025.12.05.692539v1
051
Reposted by Deen Sun
Max Planck Institute for Medical Research @mpi-mr.bsky.social · 06/11/2025
🎉🌟Big news! Our Director @kjohnsson.bsky.social has received an @erc.europa.eu Synergy Grant, together with teams from EPFL @sulianamanley.bsky.social and @unibe.ch! 👏They’ll explore how mitochondria communicate with other cell parts🔬 #ERCSyG #maxplanck #mpimr #science www.mr.mpg.de/14662972/erc...
mr.mpg.de
ERC Synergy Grant for MPI Director Kai Johnsson
2225
Reposted by Deen Sun
Max Planck Institute for Medical Research @mpi-mr.bsky.social · 18/09/2025
😎 Back from our #scientificretreat 2025 in Neckarsulm, full of scientific exchange and #teamspirit! 🤩🌟One highlight was the tour of the Bildungscampus in Heilbronn, where two new departments of our institute will be established, and the Innovation Park for #AI #IPAI 🚀 #maxplanck #mpimr #letsmingle
032
Reposted by Deen Sun
Saloni @scientificdiscovery.dev · 21/07/2025
Recently I learnt that EMBL-EBI has a free online course about AlphaFold — how it works, strengths and limitations, how to use it — and it's very good! There are also little quizzes and interactives. www.ebi.ac.uk/training/onl...
ebi.ac.uk
AlphaFold - A practical guide
AlphaFold - A practical guide
223897
Reposted by Deen Sun
Gene Chong @chongg.bsky.social · 15/07/2025
#glycotime Legionella effector LtpM is found to recognize strict two-residue sequons for site-specific O-glucosylation with minimal perturbations to a target protein and is used to show that O-glucose can act as a constitutively active O-GlcNAc mimic www.nature.com/articles/s41...
nature.com
Protein β-O-glucosylation by Legionella LtpM through short consensus sequons G-T/S and S-G - Nature Chemical Biology
Legionella effector LtpM is found to recognize short two-residue sequons, enabling site-specific O-glucosylation with minimal perturbations to a target protein, and is used to show that O-glucose can ...
053
Reposted by Deen Sun
Kai Johnsson @kjohnsson.bsky.social · 03/07/2025
Finally out in Nature Chem Bio: SNAP-tag2 for faster and brighter protein labeling www.nature.com/articles/s41... Thank you Steffi and Veselin.
nature.com
SNAP-tag2 for faster and brighter protein labeling - Nature Chemical Biology
SNAP-tag is a widespread tool for labeling protein for bioimaging. Now, Kühn et al. report SNAP-tag2 with increased labeling kinetics and brightness, which translates into a better performance in live...
217275
Reposted by Deen Sun
Kai Johnsson @kjohnsson.bsky.social · 09/07/2025
Teaching an old bacterial protein new tricks: Fast, bright and reversible rhodamine tags for live-cell imaging: www.biorxiv.org/content/10.1... Congratulations to Julian Kompa and the entire team.
biorxiv.org
Fast, Bright and Reversible Rhodamine Tags for Live-Cell Imaging
We present Rho-tag and SiR-tag, engineered protein tags derived from bacterial multidrug-resistance proteins that bind unsubstituted (silicon-) rhodamines with nanomolar affinity, enabling fast, rever...
05122
Reposted by Deen Sun
Kai Johnsson @kjohnsson.bsky.social · 10/07/2025
Molecular recording of cellular protein kinase activity with chemical labeling: www.nature.com/articles/s41... Congratulations to De-en Sun and the entire team.
nature.com
Molecular recording of cellular protein kinase activity with chemical labeling - Nature Chemical Biology
Molecular recorders based on kinase activity-dependent protein labeling track specific kinase activities to understand their link to cellular phenotypes in heterogeneous cell populations and in vivo.
02311