Sign in

David Mai

@davemai.bsky.social
7 followers 6 following 5 posts

postdoc @fredhutch.org @uwproteindesign.bsky.social | made via @hprscholars.bsky.social + penn + berkeley

PostsRepliesMedia
David Mai @davemai.bsky.social · 24/11/2025
amazing tech dev - it wasn't that long ago that i was testing singular and a few multiplexed KOs in a non-pooled comparison format www.biorxiv.org/content/10.1...
biorxiv.org
000
David Mai @davemai.bsky.social · 03/11/2025
really cool gene expression control method using a drug-controlled stem loop structure! www.nature.com/articles/s41...
nature.com
A portable poison exon for small-molecule control of mammalian gene expression - Nature Methods
This work introduces Cyclone, an acyclovir-controlled cassette that enables regulation of both transgene and endogenous gene expression with minimal background activity.
010
Reposted by David Mai
Samuel King @samuelhking.bsky.social · 17/09/2025
Many of the most complex and useful functions in biology emerge at the scale of whole genomes. Today, we share our preprint “Generative design of novel bacteriophages with genome language models”, where we validate the first, functional AI-generated genomes 🧵
35020
David Mai @davemai.bsky.social · 18/08/2025
phagocytic T cells! www.nature.com/articles/s41...
nature.com
Expanding the cytokine receptor alphabet reprograms T cells into diverse states - Nature
Orthogonal chimeric receptors containing intracellular domains for IL-4R, IL-20R, IL-22R and GCSFR reprogram T cells to promote distinct natural and synthetic cell states with functional and therapeut...
000
Reposted by David Mai
Nick Desnoyer @nickdesnoyer.bsky.social · 11/08/2025
Introducing the 1,000 Flower Collection 🧬🌹 I’m creating 1,000 genetically designed flowers each crafted with new colors, patterns, and shapes. Here’s how I’m making it happen… and how you can join me on this journey 🧵(1/7)
213667
Reposted by David Mai
Stand Up for Science Washington @sufswa.bsky.social · 13/05/2025
Hello Seattle! We are excited to present the Science for All rally next Sunday, 5/18, from 9-11am on the Seattle Waterfront! Please sign up via our Mobilize link (www.mobilize.us/mobilize/eve...) if you plan on attending. Hope to see you there!
174
Reposted by David Mai
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 16/05/2025
Two great talks lined up for the final Friday Afternoon Seminars of the season! For everyone @FredHutch.bsky.social, join us at 4pm in Pelton to hear about the latest discoveries from Rina Hirano in the Tsukiyama Lab and @christinakuismi.bsky.social in Human Biology’s @behnamnabet.bsky.social Lab.
Friday Afternoon Seminar (FAS), this Friday 5/16 at 4pm in Pelton.
 
Rina Hirano, Tsukiyama Lab
Elucidating 3D chromatin structure and its regulatory mechanism of rDNA in quiescence
 
Christina Kuismi, Nabet Lab
Targeted degradation of non-receptor tyrosine kinases PYK2 and FAK
042
David Mai @davemai.bsky.social · 15/05/2025
Amazing and inspiring @urnov.bsky.social!
nytimes.com
Baby Is Healed With World’s First Personalized Gene-Editing Treatment
000
Reposted by David Mai
Harmit Singh Malik @harmitmalik.bsky.social · 05/05/2025
Really excited to share the final version of Rechel Geiger’s PhD thesis paper with help from friends www.science.org/doi/10.1126/... Rechel is now back in medical school training to become a kickass physician-scientist
science.org
Heterozygous and generalist MxA super-restrictors overcome breadth-specificity trade-offs in antiviral restriction
Two evolutionary strategies allow the antiviral protein MxA to evolve simultaneous super-restriction against multiple viruses.
210125
Reposted by David Mai
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 19/12/2024
Great news! 4 postdocs in Basic Sciences @FredHutch.bsky.social will receive WRF fellowships. Congrats Allie Cheney in the Talbot Lab, @davemai.bsky.social in the @sanjaysrivatsan.bsky.social Lab, Sara Sunshine in the @jbloomlab.bsky.social, and Alina Lorant in the Koch Lab!
buff.ly
Washington Research Foundation awards 12 three-year postdoctoral fellowships
/PRNewswire-PRWeb/ -- Washington Research Foundation (WRF) has awarded three-year postdoctoral fellowships to 12 early-career researchers to enable them to...
043
David Mai @davemai.bsky.social · 24/11/2024
it's good to be back philly
020