A deep-learning model trained on electrocardiogram (ECG) waveforms identifies an easily visible biomarker that predicts sudden cardiac death more accurately than the current clinical state of the art.

Molecular Psychiatry - Widespread synaptic density loss in schizophrenia follows molecular and network architecture

Children’s cognitive abilities vary across short and long timescales, from circadian fluctuations to year-by-year developmental changes. “Summer sl...

Adenosine signalling is identified as the central mechanism of action of the antidepressant effects of ketamine and electroconvulsive therapy, and newly developed analogues of ketamine exhibit improved antidepressant efficacy with reduced side effects.

We introduced a simplified variant of FROG, the winning algorithm of the TADPOLE challenge, for predicting dementia progression using multimodal longitudinal data. Combining the longitudinal-to-cross...

We compared large-scale brain age models versus models trained from scratch to predict specific brain health outcomes (i.e., direct models) in the context of Alzheimer disease dementia. Our results e....

Serino et al. show that seeing an infectious avatar approach the body in virtual reality triggers an immune response, indicating that the brain prepares the body to fight infections even for perceived...

Using a relatively large and diverse sample of mostly young adults, this study by Banellis, Rebollo and colleagues examines associations between regional stomach–brain coupling and mental health and i...

Research on Drosophila neurons shows links between the need to sleep and aerobic metabolism, indicating that the pressure to sleep may have a mitochondrial origin.

How brain networks and cognition co-evolve during development remains poorly understood. Using longitudinal data collected at baseline and Year 2 from 2,949 individuals (ages 8.9-13.5) in the Adolesce...

Nature Neuroscience - The brain and body are necessarily connected. Here the authors show that brain blood flow and electrical activity are coupled with systemic physiological changes in the body.

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