We present a tour de force of atomistic molecular dynamics simulations involving the coordinated effort of 14 research groups of the Ascona B-DNA Consortium (ABC). This initiative provides a complete characterization of the 2080 DNA hexamers embedded in 190 carefully selected 20-mer duplexes, each simulated in replicate for at least 10 microseconds in explicit solvent. The consortium generates 0.25 petabytes of data, capturing millisecond-scale ensembles at the oligomer level and dynamics up to 10−1 seconds at the base-pair level. Analysis yields a comprehensive description of sequence-dependent DNA properties, including rare events such as backbone transitions, reversible base-pair changes, and partial unfolding. Processing these atomistic ensembles reveals a hidden physical code of DNA, helping explain rules of genome composition and evolution beyond coding regions. This community effort delivers unprecedented, validated FAIR data to support coarse-grained and AI models of DNA at cel

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Two deaths have been identified ​as part of a cyclosporiasis outbreak affecting Michigan, ‌the state's health department said on Monday.Both individuals had significant underlying health conditions th...

Abolishing DHS and reorganizing its components can save billions annually and alleviate the mounting pressure on civil liberties that we have experienced under everexpanding homeland security bureaucr...

General Hospital paid tribute to Anthony Geary at the end of the episode that aired on Friday, January 3. The touching memorial is the first of many that the ABC soap plans to remember the late actor. “Tony was a master craftsman,” Nancy Lee Grahn says in the tribute video. “He was a deep thinker, curious, generous, and delightfully naughty — that was my favorite part about him.”