The Francis Crick Institute @crick.ac.uk · 6hThis research, which involved developing a replica bone model, was carried out by Stefania di Blasio and Tatiana Rizou in the Tumour-Host Interaction Lab, led by Ilaria Malanchi, and built upon previous work from Laurie Gay. 010
The Francis Crick Institute @crick.ac.uk · 6hResearchers at the Crick have shown that a surge in immune cell production in response to an indirect injury or infection can reactivate dormant cancer cells inside the bone, potentially leading to relapse. www.crick.ac.uk/news/2026-10-01_inf…crick.ac.ukInflammation can wake up dormant cancer cellsResearch shows that ‘sleeping’ cancer cells hidden in the bone can be reactivated by a surge in immune cell production, offering scientists fresh insights into cancer relapse. 361
The Francis Crick Institute @crick.ac.uk · 7hOur Doctoral Clinical Fellows programme is open to clinicians: www.crick.ac.uk/careers-and-...crick.ac.ukDoctoral clinical fellowsThe Crick’s PhD training programme for clinicians. 010
The Francis Crick Institute @crick.ac.uk · 7hThe Future Leaders in Biomedical Sciences Scholarships are open to candidates of Black or mixed Black heritage: www.crick.ac.uk/careers-and-...crick.ac.ukFuture Leaders in Biomedical Sciences ScholarshipsOpen to candidates of Black or mixed Black heritage only. 143
The Francis Crick Institute @crick.ac.uk · 7hThe Crick PhD programme is open to all: www.crick.ac.uk/careers-stud...crick.ac.ukPhD student recruitmentPhD recruitment is now open until 3 November. 110
The Francis Crick Institute @crick.ac.uk · 7hPhD recruitment is now open at the Crick, and we're looking for people to join a community of researchers tackling big scientific questions in the heart of London. Apply by 3 November: www.crick.ac.uk/careers-and-... Find out more about the three routes into our 2027 PhD programme in this thread ⬇️crick.ac.ukPhD studentsOur PhD programme attracts the brightest scientific minds and is an opportunity for talented people to embark on their career in biomedical research. 142
The Francis Crick Institute @crick.ac.uk · 30/09/2026γδ T cells don’t fit neatly into the immune system’s traditional categories. Crick and King’s researchers found that these cells use adaptive immune receptors to drive rapid, innate-like responses to tissue stress, inflammation, and cancer. www.crick.ac.uk/news/2026-09...crick.ac.ukImmune cells defy textbook classificationsResearchers at the Francis Crick Institute, King’s College London and Complutense University of Madrid have shown that γδ T cells use adaptive immune receptors to drive rapid, innate-like responses to... 071
The Francis Crick Institute @crick.ac.uk · 29/09/2026We're looking for undergraduate students at UK universities who are interested in scientific research to join one of our labs or facilities for 12 months as part of our sandwich student programme. Apply by 6 October: www.crick.ac.uk/careers-and-study/s…crick.ac.ukSandwich studentsSandwich students join one of the Crick’s research groups or science technology platforms for 12 months to work on a research project. 058
The Francis Crick Institute @crick.ac.uk · 29/09/2026Our AI for Biological Discovery online seminar series continues with “Communities of AI agents for scientific discoveries” by James Zou, Stanford University, on 7 October at 15:00 BST. Register now for the webinar: www.eventbrite.co.uk/e/ai-in-biol...eventbrite.co.ukAI in Biology Seminar | Professor James ZouA new AI for Biological Discovery Seminar Series, presented by the Francis Crick Institute. 164
The Francis Crick Institute @crick.ac.uk · 28/09/2026Applications are open for our new AI/ML clinical fellowships, combining formal MSc-level training in AI and machine learning with PhD or postdoctoral research at the Crick. Find out more about the programme and apply by 11 November: bit.ly/4hxmAgncrick.ac.ukAI/ML clinical fellowsOur clinical training pathway integrating AI and machine learning with discovery research. 055
The Francis Crick Institute @crick.ac.uk · 28/09/2026“I think what motivates me to work on TB is that I always wanted to work on something relevant and important for humans.” Watch @maxgg.bsky.social discuss his journey to developing new methods to visualise TB and antibiotics inside cells. youtu.be/wzGqJszqh-syoutu.beWhy can bacteria live inside us for decades? - Max Gutierrez - LifeworksYouTube video by The Francis Crick Institute 083
The Francis Crick Institute @crick.ac.uk · 28/09/2026Researchers have identified a response to a rhinovirus infection in which airway cells physically remove infected neighbours from the tissue. The process helps protect the airway, but it might also help the virus spread. Read the full story: www.crick.ac.uk/news/2026-09...crick.ac.ukFirst defence: how airways remove infected cellsThe immune system kicks into gear to fight back against viruses, bacteria or other threats. But an ancient process is likely defending us even earlier. 150
The Francis Crick Institute @crick.ac.uk · 24/09/2026Our Chief AI Scientist, Mihaela van der Schaar, contributed to a @cellpress.bsky.social feature on AI in biomedical research, joining seven other researchers to discuss the opportunities and challenges ahead. Real the full article: www.cell.com/cell/fulltex... 042
The Francis Crick Institute @crick.ac.uk · 24/09/2026Zooming out on cancer: how it rewires our biology, from tissues to organs and whole-body systems. Researchers Caroline Hill, Ilaria Malanchi and @adrover.bsky.social are helping to unravel this vast complexity, opening up new opportunities to tackle the disease. www.crick.ac.uk/news/2026-08...crick.ac.ukCancer: the bigger pictureBold ideas and cross-disciplinary science are revealing how cancer rewires cells, tissues and whole-body systems. 0105
The Francis Crick Institute @crick.ac.uk · 24/09/2026Our next Medicine at the Crick event on 19 November explores 'not-so-acute' infections: viruses and bacteria that can persist in the body long after infection. Book online and in-person tickets ➡️ www.eventbrite.co.uk/e/medicine-a... 123
The Francis Crick Institute @crick.ac.uk · 23/09/2026Discover the latest issue of The Crick magazine, featuring stories on cancer, antimicrobial resistance, life after a Nobel Prize, liver health, heat and the human body, and more from across the Crick. Read now: www.crick.ac.uk/news-and-features/t… 085
The Francis Crick Institute @crick.ac.uk · 15/09/2026“The scientific endeavour is a global endeavour, and crossing both geographical boundaries and scientific boundaries is key to success.” Our Director Edith Heard joined The Life Scientific today, discussing her global career in research. Listen on BBC Sounds: www.bbc.co.uk/sounds/play/...bbc.co.ukThe Life Scientific - Edith Heard on unravelling the mystery of X-chromosome inactivation - BBC SoundsEpigeneticist Edith Heard on decoding the details of how X chromosomes are expressed. 020
The Francis Crick Institute @crick.ac.uk · 11/09/2026Gaining a better understanding of this mechanism, which was recently published in a collaborative study led by @sangerinstitute.bsky.social and published in @science.org, could help develop therapies with fewer negative side effects in the future. 000
The Francis Crick Institute @crick.ac.uk · 11/09/2026Group Leader @foadrouhani.bsky.social is working with his team to try and figure out why children who receive platinum-based chemotherapy have a higher number of DNA changes in their liver cells that may increase the risk of developing cancer. bit.ly/3UIbYDC bit.lyProtecting the liver from the long-term effects of cancer treatmentLife-saving chemotherapy treatment can have a hidden impact on the liver later in life, so researchers are investigating how to protect healthy tissues. 270
The Francis Crick Institute @crick.ac.uk · 09/09/2026We’re excited to announce five new group leaders will join the Crick in the coming months. Welcome to Katya Osipova, @joshuabull.bsky.social, @vchandra.bsky.social, @sami-c.bsky.social and James Cranley, whose specialties range from artificial intelligence to cell biology. bit.ly/3SPC6vJ bit.lyFive new group leaders to launch ambitious research programmes at the CrickThe Francis Crick Institute has announced the researchers selected to establish new labs at the institute, following an international recruitment round that attracted a record number of applications. 0345
The Francis Crick Institute @crick.ac.uk · 08/09/2026Our Director and CEO Edith Heard recently spoke to Nature Reviews Drug Discovery about the benefits of taking an un-siloed approach to discovery research and her vision for harnessing interdisciplinary science and AI to tackle major challenges in human health. go.nature.com/4yws7dXnature.comUn-siloed biomedical opportunitiesEdith Heard, CEO of the Francis Crick Institute, discusses the need to break down biomedical boundaries. 061
The Francis Crick Institute @crick.ac.uk · 07/09/2026Early bird tickets are available until 15 October for Stemness, Regeneration and Immunity: from development to therapy. This two-day symposium will explore the biological intersections that shape development, tissue repair, immunity and next-generation therapies. bit.ly/4r6JfVaeventbrite.co.ukStemness, Regeneration and Immunity: from development to therapyExploring the biological intersections that shape development, tissue repair, immunity and next-generation therapies. 031
The Francis Crick Institute @crick.ac.uk · 28/08/2026Free tickets are now available to our Translational Research Symposium on Monday 16 November. The event will showcase our own translational programmes and connect scientists with industry, investor professionals and ecosystem developers. bit.ly/46unl4seventbrite.co.ukCrick Translational Research SymposiumSave the date for the second edition of the Crick Translational Research Symposium! 000
The Francis Crick Institute @crick.ac.uk · 24/08/2026Join us for our first online AI for Biological Discovery Seminar, where our Chief AI Scientist Mihaela van der Schaar will host Caroline Uhler to discuss her research at the intersection of machine learning, statistics and genomics. Learn more and book your free ticket: bit.ly/4xAvNLLbit.lyAI in Biology Seminar | Professor Caroline UhlerA new AI for Biological Discovery Seminar Series, presented by the Francis Crick Institute. 0118
The Francis Crick Institute @crick.ac.uk · 21/08/2026This research was carried out by Lorenza Iolanda Tsansizi and Sophie Guan from the Antimicrobial Defence Lab, led by Veni Papayannopoulos, in a collaboration with the DNA Recombination and Repair Lab, led by Steve West. 000
The Francis Crick Institute @crick.ac.uk · 21/08/2026Researchers at the Crick have discovered how cells build neutrophil extracellular traps, or NETs, which help our immune cells capture larger pathogens such as parasites and fungi to protect us from infection. bit.ly/4wyOWvXbit.lyBack of the ‘NET’: how DNA web structures keep inflammation confinedNet-like structures made of DNA and antimicrobial proteins protect the body from infection by trapping and containing large pathogens. New findings published in the journal Science show that a DNA rep... 1168
The Francis Crick Institute @crick.ac.uk · 18/08/2026The project is led by @racheledgar.bsky.social, who runs a lab on infectious disease at @imperialcollegeldn.bsky.social and the Crick, and @anikasinga.bsky.social, a consultant virologist and researcher in adult infectious disease at Imperial, in collaboration with @pirbrightinst.bsky.social. 000
The Francis Crick Institute @crick.ac.uk · 18/08/2026Supported by a grant from @theflulab.bsky.social, researchers are investigating whether we can reduce the spread of respiratory viruses by inactivating them while they are still airborne. www.crick.ac.uk/news/2026-08-18_spr… crick.ac.ukSpray to stop the flu virus in its tracksRespiratory viruses causing conditions like Covid-19 and flu are hard to control as they spread easily through the air. A new project between the Crick, Imperial and the Pirbright Institute asks if we... 142
The Francis Crick Institute @crick.ac.uk · 12/08/2026Join Group Leader @nmoris.bsky.social as she explains how her lab is unlocking new insights into how embryos form by studying developmental models. youtu.be/A6EnwCKM3W8youtu.beHow Do We Study How Embryos Grow? – with Naomi MorisYouTube video by The Francis Crick Institute 030
The Francis Crick Institute @crick.ac.uk · 11/08/2026“I believe my findings are just the tip of a bigger iceberg.” Read more about the work from Alessandro, a postdoc in our Organ Development and Physiology Lab led by @irenemiguel-aliaga.bsky.social, who studied changes in the female intestine during and after reproduction: bit.ly/4bElX2u 0121
The Francis Crick Institute @crick.ac.uk · 06/08/2026Researchers at the Crick and @kingscollegelondon.bsky.social have deepened our understanding of how evolution often fine-tunes existing molecular mechanisms, such as the cell membrane, and how that can lead to extraordinary diversity between species. bit.ly/4wdeSgFbit.lyHow evolution fine tunes molecular mechanisms to create and maintain membrane diversity between speciesMost cells share the same fundamental molecular machinery, but evolution has produced extraordinary diversity in form and function across species by subtly adjusting how that machinery behaves. 061
The Francis Crick Institute @crick.ac.uk · 03/08/2026“I didn’t think we could cure this condition, but I now do.” In a profile interview, Veronica Kinsler reflects on one amazing evening of scientific discovery that opened up the possibility of a cure for congenital melanocytic naevi (CMN). Watch the full interview: youtu.be/Gqtm6G587SQ 051
The Francis Crick Institute @crick.ac.uk · 29/07/2026This research was carried out by Tom Calcraft from the Structural Biology of Cells and Viruses Lab, led by Peter Rosenthal, and Miguel Hernandez Gonzales from the Cellular Signalling and Cytoskeletal Function Lab, led by @drmichaelway.bsky.social. 041
The Francis Crick Institute @crick.ac.uk · 29/07/2026Scientists at the Crick have identified three crucial proteins that make up the ‘portal complex’ in the vaccinia poxvirus. The finding could lead to new ways of treating other poxviruses like mpox which have similar portal complexes. bit.ly/45vMhbi bit.lyTuning into the channel helping poxviruses replicateUncovering the structure of the poxvirus ‘portal complex’, a channel used by the virus to release its genetic material into infected cells, could help develop new antiviral treatments. 122
The Francis Crick Institute @crick.ac.uk · 28/07/2026Our clinical director Charlie Swanton spoke to James Gallagher on Inside Health this morning about his team's work investigating the biological processes that link inflammation and lung cancer. Catch up on BBC Sounds from 5:35 www.bbc.co.uk/sounds/play/m002zggrbbc.co.ukInside Health - Is inflammation behind all chronic disease? - BBC SoundsHow understanding inflammation could transform treatments from cancer to Alzheimer’s. 041
The Francis Crick Institute @crick.ac.uk · 24/07/2026Following his death from lymphoma, Edward Speed left his body to PEACE, a study revealing the hidden impacts of cancer treatment, including how DNA in healthy tissue might change. Read more about Edward’s story and the @cancerresearchuk.org-funded PEACE study: bit.ly/4x0KKplcrick.ac.ukA legacy written in DNADistinctive patterns of DNA mutations in otherwise healthy tissue could help scientists understand the lasting effects of both cancer and the treatments used to beat it. 020
The Francis Crick Institute @crick.ac.uk · 17/07/2026Last week we held our annual Bring Your Culture to Work Day. The Crick community came together to share and celebrate each others’ cultures through food, clothes, art, music and activities - from fan making to Salsa dancing. 072
The Francis Crick Institute @crick.ac.uk · 16/07/2026Our new free exhibition, We Go Way Back, opens today. Stop by and learn how revolutionary ancient DNA research reveals the deep connections that link us all. We’re open Wednesday – Saturday with late opening on Wednesday evenings. bit.ly/4frAkZ4 0132
Reposted by The Francis Crick InstituteSense about Science @senseaboutsci.bsky.social · 08/06/2026Do you or someone you know work tirelessly to stand up for science? Then enter your nominations now for the 2026 John Maddox Prize, supported by @royalsociety.org Enter or nominate 👇 johnmaddoxprize.awardstage.com#!/p0johnmaddoxprize.awardstage.comThe John Maddox Prize - AwardStage 267
The Francis Crick Institute @crick.ac.uk · 14/07/2026Find out more about this new research from @zenahadjivasiliou.bsky.social's lab at the Crick and @ucl.ac.uk 050
The Francis Crick Institute @crick.ac.uk · 13/07/2026Join us on 2 November for the 29th Molecular Haemopoiesis Conference, an annual UK-European meeting on blood cell development, stem cells, gene regulation & leukemia, with keynote speaker @cmullighan.bsky.social Book your virtual or in-person tickets now: bit.ly/4gAC1FGbit.lyMolecular Haemopoiesis 29Molecular Haemopoiesis is an annual UK-European meeting on blood cell development, stem cells, gene regulation & leukemia. 023
The Francis Crick Institute @crick.ac.uk · 08/07/2026Nearly 40 Crick scientists, staff, friends and family were part of the 35,000 people who marched in this year’s London Pride. Thanks to everyone who joined us to celebrate everything that Pride represents, and to remind people of the day-to-day challenges that still exist in LGBTQIA+ communities. 0110
The Francis Crick Institute @crick.ac.uk · 06/07/2026Myricx Bio, a cancer therapy spinout based on research carried out at the Crick and @imperialcollegeldn.bsky.social, has reached an agreement to be acquired by @novartis.bsky.social. www.crick.ac.uk/news/2026-07...crick.ac.ukCrick and Imperial spinout agrees to be acquired by NovartisMyricx Bio, a cancer therapy spinout based on research carried out at the Francis Crick Institute and Imperial College London, has reached an agreement to be acquired by Novartis. 071
The Francis Crick Institute @crick.ac.uk · 03/07/2026The work was a collaboration between @zenahadjivasiliou.bsky.social's team at the Crick, with Harry Booth carrying out modelling work, and Aleksandar Vještica’s team at @unil.bsky.social, with Celso Martins driving the experiments. 010
The Francis Crick Institute @crick.ac.uk · 03/07/2026Scientists have combined theory and experiments to show that genetic differences in seemingly identical yeast sex cells evolved due to competing demands during the asexual and sexual phases of their life cycle. bit.ly/3Tf7Utybit.lyThe evolutionary pressure behind sexual asymmetryA major transition in evolution is the shift from asexual to sexual reproduction in early organisms. But why would a yeast cell, which usually reproduces asexually, choose to mate with a very differen... 170
The Francis Crick Institute @crick.ac.uk · 02/07/2026Group leader @pippa-matt.bsky.social and her team, the HBV Elimination Lab, are working with an international team of research groups to better understand the impact of scaling up hepatitis B treatment on African populations. bit.ly/4weLN4S 021
The Francis Crick Institute @crick.ac.uk · 01/07/2026This research was led by @ssegurabayona.bsky.social with corresponding author Simon Boulton @boultonlab.bsky.social. 000
The Francis Crick Institute @crick.ac.uk · 01/07/2026Often mutated in cancer, the ATRX gene helps cells copy their DNA without damage. Crick scientists have uncovered new functions for this gene that might leave ATRX-deficient cancer cells vulnerable to potential treatments. bit.ly/4v7HTcWcrick.ac.ukLoss of DNA protector gene exposes vulnerabilities in cancerous cellsOften mutated in cancer, the ATRX gene helps cells copy their DNA without damage. Crick scientists have uncovered new functions that leave ATRX-deficient cancer cells vulnerable. 183
The Francis Crick Institute @crick.ac.uk · 30/06/2026Congratulations to @pontus-skoglund.bsky.social on being elected as a member of @embo.org. Read more about Pontus and his lab’s work using ancient DNA to redefine how scientists understand human evolution, disease, and migration. bit.ly/3QNZrggcrick.ac.ukPontus Skoglund elected to EMBO MembershipPontus Skoglund has been elected to the prestigious membership of the European Molecular Biology Organization (EMBO), an honour that recognises outstanding achievements in the life sciences. 0111
The Francis Crick Institute @crick.ac.uk · 24/06/2026Crick researchers have found specific immune responses in the lungs that could provide clues as to why some people develop active tuberculosis (TB), while others keep it in check. This research was led by Will Branchett with corresponding author Anne O’Garra. www.crick.ac.uk/news/2026-06...crick.ac.ukThe early immune clues that determine who develops TBAn early view of the immune response to bacteria in the lungs provides clues as to why some people keep TB in check, while others develop disease, suggesting new ways to intervene earlier and stop TB. 060