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CortésLab

@corteslab.bsky.social

153 followers 178 following 11 posts

We study DNA topology, the action of topoisomerses and DNA break repair to understand genome organization, dynamics and stability @cniostopcancer.bsky.social repairome.bioinfo.cnio.es

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CortésLab @corteslab.bsky.social · 09/10/2025

Looking forward to reading that!

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Reposted by CortésLab

ramsdenlab.bsky.social @ramsdenlab.bsky.social · 08/10/2025

Also: Research positions in the Ramsden lab. Post doctoral position - 5 years funding available. Cross-country collaborative, working closely with the groups of Gupta, Rothenberg, Wood, and Doublie. Some example pubs from the last two post docs: PMIDs 37968395,35927262, 2963245, 30213916, 26240371

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CortésLab @corteslab.bsky.social · 06/10/2025

In this screen the system is blind to HR. Repeating with an homologous template is in the pipeline. Muchas gracias! 😘

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CortésLab @corteslab.bsky.social · 06/10/2025

Thanks a lot Benjamin. Glad you like it!

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CortésLab @corteslab.bsky.social · 06/10/2025

Thanks Iván! I also hope so 😀

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CortésLab @corteslab.bsky.social · 06/10/2025

Thanks so much, Juanma! Excited to discuss the paper in a couple of weeks at the Social DNAing Webinar Series. Grateful for the invitation!

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CortésLab @corteslab.bsky.social · 06/10/2025

Thanks Emilio!

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CortésLab @corteslab.bsky.social · 06/10/2025

Thanks Nuria! Hope it's a useful resource for the cancer genomics field

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CortésLab @corteslab.bsky.social · 04/10/2025

Check out our web tool to see interactive networks of DSB repair genes, browse your gene of interest for its contribution to DSB repair profiles and analyze functional relationships based on similarities in repair patterns Enjoy!!! repairome.bioinfo.cnio.es

repairome.bioinfo.cnio.es

REPAIRome

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CortésLab @corteslab.bsky.social · 04/10/2025

Congratulations to all the people involved, also in Ana Losada's @rfleiro.bsky.social @gmaci.bsky.social labs @cniostopcancer.bsky.social Specially leading authors Ernesto López de Alba @israelsalguero.bsky.social Daniel Giménez Llorente Very proud of you!!!

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CortésLab @corteslab.bsky.social · 04/10/2025

We provide: - A catalog of how more than 18K genes affect DSB repair sequence outcomes induced by CRISPR-Cas9 - Examples of how it can be used at different levels, from identifying novel factors and functional relationships, to explaining mutational signatures in cancer

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CortésLab @corteslab.bsky.social · 04/10/2025

Kickstarting our Bluesky🦋 account with great news! Our REPAIRome study finally out today in @science.org www.science.org/doi/10.1126/...

science.org

A comprehensive genetic catalog of human double-strand break repair

The analysis of DNA sequence outcomes provides molecular insights into double-strand break (DSB) repair mechanisms. Using parallel in-pool profiling of Cas9-induced insertions and deletions (indels) w...

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