Reposted by Michael BoivinProf Peter Hotez MD PhD DSc(hon) @peterhotezmdphd.bsky.social · 13/04/2025No need to wait until September: We’ve identified the causes of autism and even some of the environmental chemicals interacting with autism genes involved early fetal neurodevelopment during pregnancy 782789844
Michael Boivin @commpharm.bsky.social · 15/04/2025New Acute Migraine Management Guidelines: - Triptans combined with NSAIDs (e.g., sumatriptan + naproxen) offer the highest net benefit - Triptan + acetaminophen is also beneficial. - Monotherapies are effective, but less so than combination therapy. www.acpjournals.org/doi/10.7326/... 010
Michael Boivin @commpharm.bsky.social · 13/04/2025Great review from JAMA on Iron deficiency in Adults. Great topic with very little CHE on the topic. jamanetwork.com/journals/jam...jamanetwork.comIron Deficiency in AdultsThis narrative review examines the screening, diagnosis, and treatment of adults with absolute iron deficiency without anemia and iron-deficiency anemia. 130
Reposted by Michael BoivinDr Martha Gulati @drmarthagulati.bsky.social · 03/04/2025#CardiacRehab #ESCPrev2025 #CVprev Smoking Cessation key component but how do we do it correctly? Study used Motivational Intervention had better cessation rates 🆚 control group ✨ NNT=4 ✨ ⬇️ ASCVD events Such an important study of what we can do in CR! @escardio.bsky.social 0128
Reposted by Michael BoivinEric Topol @erictopol.bsky.social · 13/02/2025How do GLP-1 drugs affect cognitive and mental health disorders? A comprehensive review www.nature.com/articles/s44... 1320343
Michael Boivin @commpharm.bsky.social · 04/02/2025New Liver disease review on MetALD. Nice review if you are interested in metabolic and alcohol-related liver disease MetALD: Clinical aspects, pathophysiology and treatment - JHEP Reports www.jhep-reports.eu/article/S258...jhep-reports.euMetALD: Clinical aspects, pathophysiology and treatmentMetabolic dysfunction-associated steatotic liver disease (MASLD) and alcohol-related liver disease (ALD) are the most prevalent causes of chronic liver disease worldwide. Both conditions have many pat... 010
Michael Boivin @commpharm.bsky.social · 03/02/2025Assessment and management of frailty in individuals living with dementia: expert recommendations for clinical practice - The Lancet Healthy Longevity www.thelancet.com/journals/lan... #frailty #dementiathelancet.comAssessment and management of frailty in individuals living with dementia: expert recommendations for clinical practiceFrailty complicates the care of individuals with dementia, increasing their vulnerability to adverse outcomes. This Personal View presents expert recommendations for managing frailty in individuals wi... 000
Michael Boivin @commpharm.bsky.social · 31/01/2025Psoriatic Arthritis and comorbidity management - Quick review of expert care of patients with PsA. academic.oup.com/rheumatology...academic.oup.comEnhancing current guidance for psoriatic arthritis and its comorbidities: recommendations from an expert consensus panelAbstractObjectives. The existing guidelines for PsA cover many aspects of management. Some gaps remain relating to routine practice application. An expert 000
Michael Boivin @commpharm.bsky.social · 31/01/2025New Rheumatology guideline on Sjogren Disease - Wicked condition for affected patients, for my specialty colleagues, worth a quick read. academic.oup.com/rheumatology... 000
Michael Boivin @commpharm.bsky.social · 28/01/2025MASLD pharmacotherapy review - If you are interested in learning more about the new treatments for MASLD, MASH and fibrosis, there is a great review at: www.nature.com/articles/s41... #MASLD, #NAFLD, #MASHnature.comNew advances in novel pharmacotherapeutic candidates for the treatment of metabolic dysfunction-associated steatohepatitis (MASH) between 2022 and 2024 - Acta Pharmacologica SinicaActa Pharmacologica Sinica - New advances in novel pharmacotherapeutic candidates for the treatment of metabolic dysfunction-associated steatohepatitis (MASH) between 2022 and 2024 000
Reposted by Michael BoivinDr Martha Gulati @drmarthagulati.bsky.social · 15/01/2025Redefining obesity. It is time. 📏BMI is NOT a direct measure of fat 📏BMI does NOT establish the distribution of fat 📏BMI cannot determine with excess fat is a health problem @thelancet.bsky.social Lancet Commission 📎 www.thelancet.com/commissions/... 13114
Michael Boivin @commpharm.bsky.social · 07/01/2025New diabetes in pregnancy study of oral antihyperglycemic agents vs. insulin. Insulin is still king when looking at large for gestational age measurement. jamanetwork.com/journals/jam...jamanetwork.comOral Glucose-Lowering Agents vs Insulin for Gestational DiabetesThis randomized clinical trial assesses whether treatment with oral metformin with added glyburide, if needed, is noninferior to insulin for prevention of large-for-gestational-age infants among pregn... 010
Michael Boivin @commpharm.bsky.social · 06/01/2025Physical activity and weight loss - Common question at this time of year. Moderate weight loss for aerobic exercise. Key findings: - Each 30-minute increase in weekly aerobic exercise leads to measurable reductions in weight, waist circumference, and body fat. jamanetwork.com/journals/jam... 010
Michael Boivin @commpharm.bsky.social · 02/01/2025 COPD Non-Pharm Recommendations - Nice review of infection prevention, nutrition, physical activity and smoking cessation. Commonly missed with these patients. hashtag#COPD journals.lww.com/ijom/fulltex...journals.lww.comChronic Obstructive Pulmonary Disease: Lifestyle Impact : International Journal of Preventive Medicineronic obstructive pulmonary disease (COPD) combines chronic bronchitis (airway inflammation) and emphysema (air sac destruction) caused by prolonged exposure to irritants, and poor lifestyle choices l... 010
Michael Boivin @commpharm.bsky.social · 30/12/2024New Alzheimer's Disease Guideline - 19 recommendations for clinicians. Includes recommendations for primary care clinicians as well. #Alzheimer's #guideline alz-journals.onlinelibrary.wiley.com/doi/10.1002/...alz-journals.onlinelibrary.wiley.comThe Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD‐ADRD): Executi...US clinical practice guidelines for the diagnostic evaluation of cognitive impairment due to Alzheimer's disease (AD) or a related dementia (ADRD) are two decades old. This evidence-based guideline ..... 000
Reposted by Michael BoivinJAMA @jama.com · 30/12/2024While immunocompromised individuals had a heterogeneous antibody response to RSV vaccines, those who received the adjuvanted RSVPreF3-AS01 vaccine showed better neutralization. ja.ma/4iVzJzy 0239
Michael Boivin @commpharm.bsky.social · 30/12/2024E-cigarettes are likely safer than combustible tobacco, but not safe. Increasing evidence of harm. This article reviews the CVD risk with e-cigarettes. #smokingCessation #tobacco www.wjgnet.com/1949-8462/fu...wjgnet.comE-cigarettes and arterial health: A review of the link between vaping and atherosclerosis progressionE-cigarettes and arterial health: A review of the link between vaping and atherosclerosis progression 000
Michael Boivin @commpharm.bsky.social · 28/12/2024E-cigarettes and oral health - Although safer than combustible tobacco, there are risks with e-cigarette use. Increased periodontal disease, dental caries, oral mucosal lesions and teeth staining. #e-cigarettes doi.org/10.3390/dj12...doi.orgThe Impact of E-Cigarettes on Oral Health—A Narrative ReviewBackground/Objectives: Electronic cigarettes (e-cigarettes) are commonly used by former smokers as an alternative product to conventional cigarettes and also by young adults and adolescents to deliver... 000
Michael Boivin @commpharm.bsky.social · 28/12/2024 Managing GLP-1 RA GI-related adverse effects - Common question, new review. Some new tips for your patients. #diabetes, #obesity, #GLP-1RA www.dovepress.com/dietary-reco... 031
Michael Boivin @commpharm.bsky.social · 28/12/2024Pediatric influenza vaccine effectiveness Study - We know that 6 months to 5 years is a high-risk group of influenza-related complications. The vaccine reduced the risk of ED visits, noncritical and critical influenza by about 50%. Really supports use in this group. jamanetwork.com/journals/jam... 000
Michael Boivin @commpharm.bsky.social · 19/12/2024New Long COVID Data - MMWR published today that 1 in 5 Adults experiencing long COVID had major limitations on their ability to perform daily functions. In this survey 6.4% of US adults were reporting they had long COVID when surveyed. www.cdc.gov/mmwr/volumes...cdc.govNotes from the Field: Long COVID and Significant Long...This report describes adults with Long COVID and reported limitations performing daily activities. 031
Michael Boivin @commpharm.bsky.social · 18/12/2024Dysplipidemia manage - "Lower is better for longer and the earlier the better" rdcu.be/d33UT 000
Michael Boivin @commpharm.bsky.social · 18/12/2024The Role of Primary Care in Achieving Life’s Essential 8: A Scientific Statement From the American Heart Association www.ahajournals.org/doi/10.1161/...ahajournals.orgThe Role of Primary Care in Achieving Life’s Essential 8: A Scientific Statement From the American Heart Association | Circulation: Cardiovascular Quality and OutcomesTo reduce morbidity and mortality rates of cardiovascular disease, an urgent need exists to improve cardiovascular health among US adults. In 2022, the American Heart Association issued Life’s Essenti... 010
Reposted by Michael BoivinShematologist, MD @shematologist.medsky.social · 07/12/2024Just a reminder that iron deficiency is incredibly common jamanetwork.com/journals/jam... And reference intervals are garbage. Join us at 2pm today #ASH24 in SDCC room 11 #ChoosingFairly to learn how you can work to change that!jamanetwork.comPrevalence of Iron Deficiency and Iron-Deficiency Anemia in US Females Aged 12-21 Years, 2003-2020This study examines prevalence of iron deficiency among females aged 12 to 21 years to inform future screening strategies for iron deficiency and iron-deficiency anemia. 711916
Reposted by Michael BoivinJAMA @jama.com · 29/11/2024Genital herpes is a common sexually transmitted infection caused by herpes simplex virus (HSV). This JAMA Patient Page describes genital herpes and its symptoms, diagnosis, treatment, and prevention measures. ja.ma/498JfLi 093
Reposted by Michael BoivinSTITCHES Medicine - the Best of Medical Research @medicine.stitches.today · 28/11/2024Mpox is a self-limited viral infection primarily spread through skin contact, but poses significant risks for the immunocompromised. by Titanji BK, Hazra A and Zucker J in JAMA #MedSky 📖 read the article: jamanetwork.comMpox Clinical Presentation, Diagnostic Approaches, and Treatment StrategiesThis review examines the epidemiology, transmission, clinical presentation, assessment and diagnosis, prognosis, management and treatment, and prevention of mpox. 0113
Michael Boivin @commpharm.bsky.social · 27/11/2024Smoking decreases vaccine immune response - As if we need another reason to quit, smokers have a 48% higher risk of diminished immune response to vaccines (especially COVID-19 and Hep B) www.mdpi.com/2076-393X/12...mdpi.comDoes Tobacco Smoking Affect Vaccine-Induced Immune Response? A Systematic Review and Meta-AnalysisBackground. Causing approximately 8 million deaths each year, tobacco smoking represents a significant public health concern. Evidence shows that smoking significantly impairs antibody production and ... 000
Michael Boivin @commpharm.bsky.social · 27/11/2024New review of Iron Status during pregnancy: They recommend screening during pregnancy www.sciencedirect.com/science/arti...sciencedirect.comLongitudinal evaluation of iron status during pregnancy: a prospective cohort study in a high-resource settingIron deficiency affects a large proportion of pregnant women worldwide, with potentially serious consequences for perinatal and infant outcomes, but w… 000
Michael Boivin @commpharm.bsky.social · 26/11/2024Alcohol use when using antiobesity medications - almost 50% of participants reduced alcohol. jamanetwork.com/journals/jam...jamanetwork.comAlcohol Use and Antiobesity Medication TreatmentThis cohort study examines the association of antiobesity medication use and alcohol use among participants enrolled in a weigh loss program. 000
Michael Boivin @commpharm.bsky.social · 26/11/2024New International Scabies Guidelines - Topic that is rarely discussed. Detailed review. onlinelibrary.wiley.com/doi/10.1111/...onlinelibrary.wiley.comClinical practice guidelines for the diagnosis and treatment of scabiesScabies, caused by the Sarcoptes scabiei var hominis mite burrowing into the skin, is a highly contagious disease characterized by intense nocturnal itching. Its global impact is considerable, affect.... 000
Reposted by Michael BoivinKyle Swanson, MD, FAANS, FCNS @kiswanson.medsky.network · 26/11/2024Man I'm tired of people acting as if Ozempic and GLP-1 medications are just for "vanity" or being used because people don't understand nutrition/exercise 4482
Reposted by Michael BoivinMegan Ranney MD MPH @meganranney.bsky.social · 24/11/2024Beautiful 🛟🧪🩺 719148
Reposted by Michael BoivinEric Topol @erictopol.bsky.social · 23/11/2024How well do vaccines protect vs #LongCovid, a systematic review during the Omicron era? —about 20% reduced by primary series (vs no vaccination), and —another 20% reduction by boosters vs primary series www.medrxiv.org/content/10.1... 29652178
Michael Boivin @commpharm.bsky.social · 23/11/2024Quick review of XEC variant. Worth a quick read: jamanetwork.com/journals/jam...jamanetwork.com 000
Reposted by Michael BoivinEdgar V. Lerma 🇵🇭 @edgarvlermamd.medsky.network · 16/11/2024Albuminuria, an established biomarker of the progression of CKD, is also recognized as a biomarker for the risk of CVD (ca. 2024) #Nephpearls #NephSky #Cardiorenal 👉🏼 pubmed.ncbi.nlm.nih.gov/38214258/ 1208
Reposted by Michael BoivinEdgar V. Lerma 🇵🇭 @edgarvlermamd.medsky.network · 17/11/2024Transition from an estimated glomerular filtration rate (eGFR)-based to a risk-based approach to CKD care from KDIGO #Nephpearls #NephSky 👉 kdigo.org/guidelines/c... 💻 kidneyfailurerisk.com 2145
Michael Boivin @commpharm.bsky.social · 22/11/2024 New Innovative review of Glucagon-based Therapies for Obesity Management - Current and future therapies for the management of obesity academic.oup.com/jes/article/... 000
Michael Boivin @commpharm.bsky.social · 22/11/2024New Asthma Exacerbation prevention and management review article for Primary Care - International expert review www.nature.com/articles/s41...nature.comBest practice advice for asthma exacerbation prevention and management in primary care: an international expert consensus - npj Primary Care Respiratory Medicinenpj Primary Care Respiratory Medicine - Best practice advice for asthma exacerbation prevention and management in primary care: an international expert consensus 000
Reposted by Michael BoivinHannah Ritchie @hannahritchie.bsky.social · 21/11/2024300,000 women die from cervical cancer every year. But this is a cancer we can effectively eliminate with the HPV vaccine. This is something very few people know about. Article from my colleague @scientificdiscovery.dev: ourworldindata.org/hpv-vaccinat... 11473151
Reposted by Michael BoivinDr Martha Gulati @drmarthagulati.bsky.social · 18/11/2024#AHA24 NUDGE FLU #fluvaccine 💉flu vax underused in AMI 💉study looked at impact of a letter nudge to improve flu vax rates in Denmark 🇩🇰 💉2.1 Million randomized 💉Nudge resulted in modest improvement of vax rates 💉sentence including CV sentence ⤴️ vax uptake 2108
Reposted by Michael BoivinJAMA @jama.com · 17/11/2024FINEARTS-HF trial in JAMA Cardiology: Finerenone was effective in reducing the risk of CV death and heart failure events even in patients with mildly reduced or preserved ejection fraction who experienced elevated potassium levels. #AHA24 ja.ma/4euKMwg 0118
Michael Boivin @commpharm.bsky.social · 17/11/2024New Canadian Diabetes Pharmacotherapy Guidelines in Type 2 diabetes. Updated for 2024. www.canadianjournalofdiabetes.com/article/S149... 030
Reposted by Michael BoivinDr Martha Gulati @drmarthagulati.bsky.social · 16/11/2024Dr. Guang Ning presents on the effect of intensive BP lowering in Diabetes #AHA24 #BPROAD study 🫀intensive 🆚 UC: <120 🆚 <140 SBP🎯 🫀12,821 patients enrolled 🫀45% 💃🏻 mean age 63 💥21% reduction in CV events in intensive tx ! SAE same 📎 www.nejm.org/doi/full/10.... 096
Reposted by Michael BoivinDr Martha Gulati @drmarthagulati.bsky.social · 16/11/2024#LBCT #SUMMIT trial #AHA24 💥 Treatment with tirzepatide led to ⤵️risk of a composite of death from cardiovascular 🫀 causes or worsening heart failure 🆚 placebo and improved health status in patients with HFpEF+obesity 📎 @NEJM www.nejm.org/doi/full/10.... 23822
Reposted by Michael BoivinDr Martha Gulati @drmarthagulati.bsky.social · 16/11/2024@TheLancet session at #AHA24 starting now! #obesity 🫀Malnutrition was a problem but now obesity is taking over worldwide with few exceptions 🫀Severe obesity has also ⤴️ 🫀BMI doesn’t reflect obesity as well as waist-to-height ratio 🫀⤴️ diabetes follows obesity 03820
Reposted by Michael BoivinEric Topol @erictopol.bsky.social · 16/11/2024Another GLP-1 drug success. Tirzepatide in heart failure with preserved ejection fraction (HFpEF) with longer term follow-up than 2 previous trials with semaglutide nejm.org/doi/full/10.... in people with BMI >30; no data yet for HFpEF in people without obesitynejm.orgTirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity | NEJMObesity increases the risk of heart failure with preserved ejection fraction. Tirzepatide, a long-acting agonist of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor... 324238