The endosomal Na+ /H+ exchanger HsNHE6 regulates organellar pH and is implicated in neurological disease. Here the authors determine its cryo-EM structure and show a kinetic preference for K+ over Na+...

MAASTY, a methacrylic acid–styrene copolymer, enables high-resolution structural determination of human membrane proteins in native nanodiscs, efficiently solubilizing diverse membrane proteins and pr...

It's almost time for this year's Late Late Toy Show and to celebrate we have rounded up our favourite moments from over the decades. See if you agree!

Studies on protein–protein interactions using proteins containing d- or l-amino acids show that stereoselectivity of binding varies with the degree of disorder within the complex.

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